• Biomedical Science Letters
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• v.18 no.1
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• pp.79-82
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• 2012

Acinetobacter infections are of great concern in clinical settings because of multi-drug resistance (MDR) and high mortality of the infected patients. The MDR Acinetobacter baumannii has emerged as a significant infectious agent in hospitals worldwide. The purpose of this study was to determine for molecular characterization of MDR A. baumannii clinical isolates obtained from the Wonju Christian Hospital in Gangwon province of Korea. A total of seventy nonduplicate A. baumannii isolates were collected from the Wonju Christian Hospital in Korea from March to April in 2011. All of the MDR A. baumannii isolates were encoded by $bla_{OXA-23-like}$ gene and all isolates with the $bla_{OXA-23-like}$ gene had the upstream element ISAba1 to promote increased gene expression and subsequent resistance to carbapenem. 16S rRNA methylase gene (armA) was detected in 44 clinical isolates which were resistant to amikacin, and phosphotransferase genes encoding aac(3)-Ia and aac(6')-Ib were the most prevalent. A combination of 16S rRNA methylase and aminoglycoside-modifying enzyme genes (armA, aac(3)-Ia, aac(6')-Ib, and aph(3')-Ia) were found in 31 isolates. The sequencing results for the quinolone resistance-determining region (QRDR) of gyrA and parC revealed the presence of Ser (TCA) 83 Leu (TTA) and Ser (TCG) 80 Leu (TTG) substitutions in the respective enzymes for all MDR. Molecular typing for MDR A. baumannii could be helpful in confirming the identification of a common source or cross-contamination. This is an important step in enabling epidemiological tracing of these strains.

• Journal of Ginseng Research
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• v.32 no.2
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• pp.107-113
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• 2008

In this study, we have investigated the effect of panaxatriol (PT) on phosphoinositides (PIS) breakdown and $Ca^{2+}$-elevation in thrombin-induced platelet aggregation. Thrombin (5U/ml), a potent platelet agonist which activates phospholipase $C_{\beta}$ via protease activated receptor (PAR), hydrolyzed PIS in platelet membrane. The phosphatidylinositol 4, 5-bisphosphate $(PIP_2)$ was hydrolyzed after 10 sec of the thrombin-stimulation, and both the phosphatidylinositol 4-monophosphate (PIP) and phosphatidylinositol (PI) were brokendown after 30 sec of the thrombin-stimulation. However, PT inhibited the thrombin-stimulated hydrolysis of $PIP_2$, PIP, and PI. On the other hand, thrombin increased the level of phosphatidic acid (PA) which is phosphorylated from diacylglycerol (DG) generated by PIS-hydrolysis. However, Pr inhibited the thrombin-increased PA level non-significantly. Thrombin increased cytosolic free $Ca^{2+}([Ca^{2+}])_i$) up to 72% as compared with control $(30.8{\pm}0.9 nM)$ in intact platelet. However, PT (100 ${\mu}g/ml$) inhibited the thrombin-elevated $[Ca^{2+}]_i$ to 100%. These results suggest that PT may have a beneficial effect on platelet aggregation-mediated thrombotic disease by inhibiting thrombin-induced platelet aggregation via suppression of the $[Ca^{2+}]_i$ level and PIS breakdown.

• The Journal of the Acoustical Society of Korea
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• v.21 no.4
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• pp.380-386
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• 2002

Conventional post-processing as like confidence measure (CM) proposed by Rahim calculates phones' CM using the likelihood between phoneme model and anti-model, and then word's CM is obtained by averaging phone-level CMs[1]. In conventional method, CMs of some specific keywords are tory low and they are usually rejected. The reason is that statistics of phone-level CMs are not consistent. In other words, phone-level CMs have different probability density functions (pdf) for each phone, especially sri-phone. To overcome this problem, in this paper, we propose normalized confidence measure. Our approach is to transform CM pdf of each tri-phone to the same pdf under the assumption that CM pdfs are Gaussian. For evaluating our method we use common keyword spotting system. In that system context-dependent HMM models are used for modeling keyword utterance and contort-independent HMM models are applied to non-keyword utterance. The experiment results show that the proposed NCM reduced FAR (false alarm rate) from 0.44 to 0.33 FA/KW/HR (false alarm/keyword/hour) when MDR is about 8%. It achieves 25% improvement of FAR.

• Journal of Korean Society for Atmospheric Environment
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• v.32 no.2
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• pp.216-232
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• 2016

In present, the Seoul City is undergoing traffic congestion problems caused by rapid urbanization and population growth. Thus the City government has reorganized the mass transportation system since 2004 and the subway has become a very important means for public transit. Since the subway system is typically a closed environment, the indoor air quality issues have often raised by the public. Especially since a huge amount of PM (particulate matter) is emitted from ground tunnels passing through the subway train, it is now necessary to assess the characteristics and behaviors of fine PM inside the tunnel. In this study, the concentration patterns of $PM_1$, $PM_{2.5}$, and $PM_{10}$ in the Seoul subway line-2 were analyzed by real-time measurement during winter (Jan 13, 2015) and summer (Aug 7, 2015). The line-2 consisting of 51 stations is the most busy circular line in Seoul having the railway of 60.2 km length. The the one-day average $PM_{10}$ concentrations were $148{\mu}g/m^3$ in winter and $66.3{\mu}g/m^3$ in summer and $PM_{2.5}$ concentrations were $118{\mu}g/m^3$ and $58.5{\mu}g/m^3$, respectively. The $PM_{2.5}/PM_{10}$ ratio in the underground tunnel was lower than the outdoor ratio and also the ratio in summer is higher than in winter. Further the study examined structural types of underground subsections to explain the patterns of elevated PM concentrations in the line-2. The subsections showing high PM concentration have longer track, shorter curvature radius, and farther from the outdoor stations. We also estimated the outdoor PM concentrations near each station by a spatial statistical analysis using the $PM_{10}$ data obtained from the 40 Seoul Monitoring Sites, and further we calculated $PM_{2.5}/PM_{10}$ and $PM_1/PM_{10}$ mass ratios near the outdoor subway stations by using our observed outdoor $PM_1$, $PM_{2.5}$, and $PM_{10}$ data. Finally, we could develop pollution maps for outdoor $PM_1$ and $PM_{2.5}$ near the line-2 by using the kriging method in spatial analysis. This methodology may help to utilize existing $PM_{10}$ database when managing and control fine particle problems in Korea.

• Journal of Korean Philosophical Society
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• v.117
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• pp.355-372
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• 2011

G. Deleuze a $exerc{\acute{e}}$ sa philosophie $cin{\acute{e}}mathographique$ dans ses œuvres essentielles $Cin{\acute{e}}ma$ 1: l'Image-Mouvement(Minuit:1983) et $Cin{\acute{e}}ma$ 2: l'Image-Temps(Minuit:1985) qui n'indiquent pas l'histoire $cin{\acute{e}}mathographique$ mais la taxinomie, et par $cons{\acute{e}}quent$, de l'image et du code. Cette ${\acute{e}}tude$ consiste donc $\grave{a}$ rendre compte la de l'image que G. Deleuze touche dans cette $d{\acute{e}}finition$ et $\grave{a}$ $v{\acute{e}}rifier$ quelles images peuvent ${\hat{e}}tre$ $cat{\acute{e}}goris{\acute{e}}es$: comment. Nous distinguons l'image-mouvement et l'image-temps qui sont les $cat{\acute{e}}gories$ essentielles chez $Cin{\acute{e}}ma$. C'est surtout sur ce point que nous insistons. Dans ce cas, nous discutons aussi de la question des spectateurs du film qui conduit. Cette question permet susciter de la $mani{\grave{e}}re$ $d^{\prime}{\hat{e}}tre$ des spectateurs entre le film qui est $compos{\acute{e}}$ de l'image-mouvement dont G. Deleuze decrit comme 'classique' et le film qui est $trait{\acute{e}}$ de l'lmage-temps dont il $d{\acute{e}}finit$ comme 'moderne': quelle variation. Dans ce point $d^{\prime}{\acute{e}}tude$, G. Deuleuze ecrit cette question $mentionn{\acute{e}}e$ $\grave{a}$ travers son oeuvre $Cin{\acute{e}}ma$($\grave{a}$ voir ch.7, Volume2).

• Journal of Korean Philosophical Society
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• v.126
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• pp.191-212
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• 2013

Cet article consiste ${\grave{a}}$ critiquer $l'{\acute{e}}conomie$ libidinale, $subordonn{\acute{e}}e$ ${\grave{a}}$ l'ordre phallique qui coupe les flux libidinaux. La notion lacanienne du $d{\acute{e}}sir$ qui est $focalis{\acute{e}}e$ sur le manque, ne pourrait prendre en compte la dimension $cr{\acute{e}}ative$ et productive du $d{\acute{e}}sir$ qui est $li{\acute{e}}e$ ${\grave{a}}$ la perspective deleuzienne et guattarienne du $d{\acute{e}}sir$. La $possibilit{\acute{e}}$ de la $d{\acute{e}}rive$ et de la $d{\acute{e}}stratification$ des flux libidinaux pourrait se mener vers la notion du "homo surplus", laquelle est la notion $in{\acute{e}}dite$ que j'ai $cr{\acute{e}}e$. Le surplus est ce qui $d{\acute{e}}passe$ la logique phallogocentrique par son $immensurabilit{\acute{e}}$ et sa surabondance. Dans cette perspective, la critique virulente de la notion du plaisir $cantonn{\acute{e}}$ dans la partie $g{\acute{e}}nitale$, $s^{\prime}op{\grave{e}}re$ avec l'analyse de la jouissance qui est non phallique; Cette jouissance non phallique est $li{\acute{e}}e$ ${\grave{a}}$ l'agencement non $lin{\acute{e}}aire$ et multiple des pratiques sexuelles $in{\acute{e}}dites$ et radicales.

• The Journal of Korean Society for School & Community Health Education
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• v.18 no.3
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• pp.69-82
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• 2017

Objectives: This study was conducted to investigate the relationship between general characteristics and oral health behavior, oral health knowledge, and oral health literacy for adult workers. Methods: This study chose some adult workers located D City by convenience sampling method, and accepted those who understood the purpose of the study and agreed with a survey as subjects. The final study subjects were 297 except 24 with unsound questionnaires among a total of 321 questionnaires. The contents of a survey were demographic characteristics, oral health behavior, oral health knowledge, and oral literacy, and the survey was done by a self-administered questionnaire. Results: In the verbal oral health literacy distribution based on REALM standard of the subjects, a scale of 7-8, 45-60 points by score was the highest with 62.0%. In average monthly household income and oral health knowledge level of general characteristics, oral health literacy was statistically significant, and was statistically significant according to oral health literacy, monthly income of house hold, and marital status as well, and was statistically significant in oral health knowledge and oral health literacy level according to oral health behavior and in the oral health knowledge level depending on a regular checkup. And In experience existence and nonexistence of oral health education and understanding and misunderstanding of dentistry and dental health education, and main body of the decision of dental treatment, verbal oral health literacy of oral health knowledge and oral health literacy was significant. It can be seen that based on correlation among general characteristics, oral health knowledge level, verbal oral health literacy, and functional oral health literacy, there is a correlation among gender and education level, age and average monthly income, and age and marital status. Conclusions: This study presented the need for oral health literacy along with the oral health knowledge of oral health behavior affecting adult workers' oral health, and tried to establish the connection among them. Accordingly, it is thought that an improvement plan of oral health literacy for the prevention and promotion of adult workers' dental disease in the future.

• Journal of Korean Society of Forest Science
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• v.110 no.4
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• pp.543-553
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• 2021

This research focused on the investigation of isoprene and terpene emissions from 30 major urban tree species. We conducted sampling using a specific dynamic enclosure system between August and September 2020. Seedlings less than three years old were enclosed in a chamber consisting of a 400 L transparent Tedlar bag. The air-flows from the chamber's outlet were sampled using Tenax-filled sorbent tubes in the presence of standard conditions (temperature: 30℃, PAR: 1,000 μmol/m²/sec). A thermal desorption GC/MS system was used to analyze 38 BVOC compounds (isoprene, monoterpene, sesquiterpene, oxygenated monoterpene, and sesquiterpene). Isoprene emitters included Phyllostachys bambusoides, Quercus serrata, Daphniphyllum macropodum, and Buxus Koreana. Monoterpene emitters included Pinus rigida, Acer pictum subsp. mono, Larix kaempfer, Magnolia denudata, Metasequoia glyptostroboides, Pinus koraiensis, Pinus densiflora, and Abies holophylla. The monoterpene emission profiles were dominated by α-pinene, myrcene, limonene, β-pinen, and sabinene, while caryophyllene and farnesene were the prominent sesquiterpenes. Predominant oxygenated monoterpene compounds were also discovered as pulegone, borneol, menthol, eucalyptol, and nerol, while caryophyllene oxide were the prominent oxygenated sesquiterpenes. Sesquiterpenes and oxygenated sesquiterpenes had relatively lower contributions for all species.

• Cross-Cultural Studies
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• v.52
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• pp.79-110
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• 2018

This purpose of this study was to address the issue of forgiving unforgivable crimes, inevitably raised in Paul Ricoeur's thoughts. He explores the possibility of righteous historical representation of tragic events in Western history. Being aware of injustices of amnesty indiscriminately extended by the government, he studied the process through in which a genuine pardon should unfold before granting amnesty. He believes that this process called the "odyssey of forgiveness" presupposes the process of "imputability," in which the perpetrator should acknowledge his/her wrongdoing as his/her act and take reasonable responsibilities for it in a modest position. However, such acknowledgement of wrongdoing cannot be any reason for the victim to necessarily grant forgiveness to the perpetrator. According to him, forgiveness is a gift and the power of love enabled by a complete forgiver only. The initiative of forgiveness is attributable to the forgiver only. To never relinquish tension between love and justice in the forgiving process, he devises a way of planning an equation of forgiveness in a vertical scheme. Finally, he explains the process of requesting and granting forgiveness in a form of a righteous historical representation against the oblivion of past tragic events. He contends that this event of forgiveness promises a new life and a new era to all seeking and granting forgiveness, and that write a righteous history in eschatological hope.

• Journal of Korean Philosophical Society
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• v.116
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• pp.257-280
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• 2010

I try to formalize the system of modal logic and interpret it in view of constructivism through this study. As to the meaning of a sentence, as we saw, Frege endorsed extensions in view of the fact that they are enough to provide for a compositional account for truth, in particular that (1) the assignment of extensions to expressions is compositional ; (2) the assignment of extensions to sentences coincides with the assignment of truth values. But nobody would be willing to admit that a truth value is what a sentence means and that consequently all true sentences are synonymous. So, if what we are after is meaning in the intuitive sense, then extensions would not do. This consideration has later become the point of departure of modal and intensional semantics. So, it is clear that the language of modal logic do not allow for an extensional interpretation. ${\square}$ is syntactically on a par with ${\vdash}$, hence within the extensional framework it would have to denote a unary truth function. This means that if modal logic is to be interpreted, we need a semantics which is not extensional. The first attempt to build a feasible intensional semantics was presented by Saul Kripke. He came to the conclusion that we must let sentences denote not truth values, but rather subsets of a given set. He called elements of the underlying set possible world. Hence each sentence is taken to denote the set of those possible world in which it is true. This lets us explicate necessity as 'truth in every possible world' and possibility as 'truth in at least one possible world'. But it is clear that the system of modal logic is not only an enlargement of propositional logic, as long as the former contains the new symbols, but that it is of an other nature. In fact, the modal logic is intensional, in that the operators do not determine the functions of truth any more. But this new element is not given a priori, but a posteriori from construction by logicist.