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Consistency of Responses to Affective Stimuli Across Individuals using Intersubject Representational Similarity Analysis based on Behavioral and Physiological Data (참가자 간 표상 유사성 분석을 이용한 정서 자극 반응 일치성 비교: 행동 및 생리 데이터를 기반으로)

  • Junhyuk Jang;Hyeonjung Kim;Jongwan Kim
    • Science of Emotion and Sensibility
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    • v.26 no.3
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    • pp.3-14
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    • 2023
  • This study used intersubject representational similarity analysis (IS-RSA) to identify participant-response consistency patterns in previously published data. Additionally, analysis of variance (ANOVA) was utilized to detect any variations in the conditions of each experiment. In each experiment, a combination of ASMR stimulation, visual and auditory stimuli, and time-series emotional video stimulation was employed, and emotional ratings and physiological measurements were collected in accordance with the respective experimental conditions. Every pair of participants' measurements for each stimulus in each experiment was correlated using Pearson correlation coefficient as part of the IS-RSA. The results of study revealed a consistent response pattern among participants exposed to ASMR, visual, and auditory stimuli, in contrast to those exposed to time-series emotional video stimulation. Notably, the ASMR experiment demonstrated a high level of response consistency among participants in positive conditions. Furthermore, both auditory and visual experiments exhibited remarkable consistency in participants' responses, especially when subjected to high arousal levels and visual stimulation. The findings of this study confirm that IS-RSA serves as a valuable tool for summarizing and presenting multidimensional data information. Within the scope of this study, IS-RSA emerged as a reliable method for analyzing multidimensional data, effectively capturing and presenting comprehensive information pertaining to the participants.

A Short form of the Gray-Wheelwright Test (단축형 그레이-휠라이트 검사)

  • Ju-Kab Lee;Sung-Hyun Kim;Yong-Wook Shin
    • Sim-seong Yeon-gu
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    • v.33 no.1
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    • pp.61-80
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    • 2018
  • We investigated whether the 81 items of the Gray-Wheelwright test correctly measure the concept of Jung's typology and aimed to refine the test. Participants (n=431) completed the Gray-Wheelwright test, and the results were analyzed using factor analysis with the varimax rotation and the maximum likelihood extraction method. A pair of opposing attitudes, introversion/extroversion, or one of the two pairs of opposing functional types, thinking/feeling or intuition/sensation, was labeled to the extracted factor according to the majority type of the items in the factor. The minority items or items not included in any factors were excluded from making a short form of the Gray-Wheelwright test with 45 items. We used intraclass correlation (ICC) coefficient and Cronbach's alpha for the test-retest reliability and internal consistency of the test, respectively. The newly developed short form of the Gray-Wheelwright test measured the Jung's personality types well, which was comparable to the original one while reducing time and effort required for the testing.

Estimation of Structural Properties from the Measurements of Phase Velocity and Attenuation Coefficient in Trabecular Bone (해면질골에서 위상속도 및 감쇠계수 측정에 의한 구조적 특성 평가)

  • Lee, Kang-Il
    • The Journal of the Acoustical Society of Korea
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    • v.28 no.7
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    • pp.661-667
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    • 2009
  • Trabecular-bone-mimicking phantoms consisting of parallel-nylon-wire arrays were used to investigate correlations of phase velocity and attenuation coefficient with structural properties in trabecular bone. Trabecular separation (Tb.Sp) of the 7 trabecular-bone-mimicking phantoms ranged from 300 to $900\;{\mu}m$ and volume fraction (VF) from 1.6% to 8.7%. Phase velocity and attenuation coefficient of the phantoms were measured by using a through-transmission method in water, with a matched pair of broadband unfocused transducers with a diameter of 12.7 mm and a center frequency of 1 MHz. Phase velocity and attenuation coefficient at 1 MHz decreased almost linearly with increasing Tb. Sp and increased almost linearly with increasing VF. The simple and multiple linear regression models with phase velocity and attenuation coefficient as independent vanables and Tb.Sp and VF as dependent variables demonstrated that the coefficients of determination for the prediction of VF were higher than those for the prediction of Tb.Sp. The results obtained in the trabecular-bone-mimicking phantoms consisting of parallel-nylon-wire arrays were consistent with those in human trabecular bone suggesting that the structural properties can be estimated from the measurements of phase velocity and attenuation coefficient in trabecular bone.

A Study on the Standardization of Sample Preparation for Urine Sediment Microscopic Examination (요침사 현미경검사를 위한 표본제작의 표준화 연구)

  • Hyeok Jae LEE;Dae Heon KIM;Min-Hyeok LEE
    • Korean Journal of Clinical Laboratory Science
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    • v.56 no.2
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    • pp.135-146
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    • 2024
  • Urinalysis is a fundamental diagnostic test routinely performed in clinical laboratories. We evaluated two manual microscopy methods, including a novel protocol, against the standardized chamber method. A total of 402 specimens, comprising 201 positive each for red blood cells (RBCs) and white blood cells (WBCs) by the strip test and automated urine sediment analyzer, were selected for the analysis. The correlation coefficients between the standardized chamber method and the novel protocol RBC and WBC test were both r=0.98, indicating a high degree of correlation. The pair-wise agreement rates for the same grade between these two methods were 86.1% for RBCs and 88.6% for WBCs, with rates within one grade difference of both at 99.5%. In contrast, the agreement rates between the standardized chamber method and smaller or medium-sized laboratory methods were notably lower, with the same-grade rates at 11.9% for RBCs and 13.4% for WBCs, and within one grade difference at 67.2% and 74.1%, respectively. Additional analyses using the intraclass correlation coefficient and Bland-Altman plots confirmed that the novel protocol exhibited superior agreement compared to the other three manual microscopy methods tested. Therefore, we recommend the novel protocol as a standardized procedure for urine sediment preparation, given its high correlation and agreement with the standardized chamber method.

Feeding Habits of the Large Yellow Croaker, Larimichthys crocea in the Coastal Waters of Jeju Island, Korea (한국 제주 연안에 출현하는 부세(Larimichthys crocea)의 식성)

  • Do-Yeon Park;Do-Gyun Kim;Seong-Yong Moon;Jeong-Ho Park;Hee-Yong Kim;Gun Wook Baeck
    • Korean Journal of Ichthyology
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    • v.36 no.2
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    • pp.182-187
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    • 2024
  • Feeding habits of the large yellow croaker, Larimichthys crocea, was studied using 816 specimens collected by large pair-trawl fishery from June 2021 to May 2022 in the coastal waters of Jeju Island, Korea. The range of total length was 19.8~57.4 cm. Using the IRI, Pisces were mainly prey component constituted 57.5%. Euphausiacea and Macrura were important prey component constituted 23.2% and 18.7%, respectively. There was a significant difference in the change in diet composition by size group. As the L. crocea grew, the feeding rate of Euphausiacea decreased and the feeding rate of Pisces increased. There were also significant differences in the changes in diet composition by seasonal group. The most important prey species for L. crocea in the winter and spring were Pisces, in the summer it was Macrura, and in the fall it was Euphausiacea. As a result of analyzing the feeding relationship between size groups and season groups, L. crocea showed significant differences in the interaction between size groups and season groups.

Effects of Sodium/Glucose Cotransporter 2 (SGLT2) Inhibitors on Cardiac Imaging Parameters: A Systematic Review and Meta-analysis of Randomized Controlled Trials

  • Caitlin Fern Wee;Yao Hao Teo;Yao Neng Teo;Nicholas LX Syn;Ray Meng See;Shariel Leong;Alicia Swee Yan Yip;Zhi Xian Ong;Chi-Hang Lee;Mark Yan-Yee Chan;Kian-Keong Poh;Ching-Ching Ong;Lynette LS Teo;Devinder Singh;Benjamin YQ Tan;Leonard LL Yeo;William KF Kong;Tiong-Cheng Yeo;Raymond CC Wong;Ping Chai;Ching-Hui Sia
    • Journal of Cardiovascular Imaging
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    • v.30 no.3
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    • pp.153-168
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    • 2022
  • Recent studies have shown that sodium/glucose cotransporter 2 (SGLT2) inhibitors might exert favourable changes on cardiac parameters as observed on cardiovascular imaging. We conducted a systematic review and meta-analysis to determine the effects of SGLT2 inhibitors on cardiac imaging parameters. Four electronic databases (PubMed, Embase, Cochrane, Scopus) were searched for studies in which the effects of SGLT2 inhibitors on cardiac imaging parameters were examined. Studies in which a population was administered SGLT2 inhibitors and analysed by echocardiography and/or cardiac magnetic resonance (CMR) imaging were included. Random-effects pair-wise meta-analysis models were utilized to summarize the studies. A total of 11 randomized controlled trials was included with a combined cohort of 910 patients. Comparing patients receiving SGLT2 inhibitors with subjects receiving placebo, the mean change in CMR-measured left ventricular mass (LVM) was -3.87 g (95% confidence interval [CI], -7.77 to 0.04), that in left ventricular end-systolic volume (LVESV) was -5.96 mL (95% CI, -10.52 to -1.41) for combined LVESV outcomes, that in left atrial volume index (LAVi) was -1.78 mL/m2 (95% CI, -3.01 to -0.55) for combined LAVi outcomes, and that in echocardiography-measured E/e' was -0.73 (95% CI, -1.43 to -0.03). Between-group differences were not observed in LVM and LVESV after indexation. The only between-group difference that persisted was for LAVi. Treatment with SGLT2 inhibitors resulted in reduction in LAVi and E/e' on imaging, indicating they might have an effect on outcomes associated with LV diastolic function.

Antibody Functionalized UiO-66-(COOH)2 Amplified Surface Plasmon Resonance Analysis Method for fM Oxytocin (펨토몰 농도의 옥시토신 검출을 위한 항체 기능성 UiO-66-(COOH)2 증폭형 표면 플라즈몬 공명 분석법 개발)

  • Myungseob Lee;Ha-Young Nam;Su Yeon Park;Sung Hwa Jhung;Hye Jin Lee
    • Applied Chemistry for Engineering
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    • v.35 no.4
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    • pp.335-340
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    • 2024
  • In this paper, we synthesized organic and inorganic hybrid materials to introduce antibody functionality to UIO-66 and incorporated them into a surface plasmon resonance (SPR) assay to enhance the sensitivity of detecting small molecules such as oxytocin. A biological marker peptide called oxytocin may help in the diagnosis of heart failure, Alzheimer's disease, and cancer. To detect oxytocin at concentrations as low as a few femtomole (fM), we developed a surface sandwich assay utilizing a pair of oxytocin-specific antibodies for enhancing selectivity and one of metal organic frameworks [e.g., UiO-66-(COOH)2] possessing high porosity and surface-area as a signal amplifier. Initially, real-time SPR assays were used to confirm that each selected oxytocin-specific antibody binds strongly to oxytocin and to different binding sites on oxytocin. One of these antibodies (e.g., anti-OXT[OTI5G4]) was immobilized on the surface of a thin gold chip. Upon sequential injecting of oxytocin and the other antibody (e.g., anti-OXT[4G11]) conjugated to UiO-66-(COOH)2 onto the surface to form the surface sandwich complex of anti-OXT[OTI5G4]/oxytocin/UiO-66-(COOH)2-anti-OXT[4G11]), SPR changes, which varied with oxytocin concentration, were then measured in real time. The results demonstrated that sensitivity was amplified by over a million-fold compared to assays without UiO-66-(COOH)2, enabling oxytocin detection down to approximately 10 fM.

Molecular Identification and Morphological Description of Juvenile of the Previously Unrecorded Species Long-snout Tonguefish, Symphurus longirostris (Cynoglossidae) from the Southern Sea of Jeju Island, Korea (한국 제주도 남부 해역에서 출현한 참서대과(Cynoglossidae) 어류 1미기록종, Symphurus longirostris 치어의 분자동정 및 형태기재)

  • Yeon-Ju Seo;Jin-Koo Kim;Hyo-Jae Yu;Se Hun Myoung
    • Korean Journal of Ichthyology
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    • v.36 no.3
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    • pp.288-294
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    • 2024
  • A juvenile of long-snout tonguefish, Symphurus longirostris belonging to the family Cynoglossidae, was collected from the waters around Jeju Island, Korea in August 2023. Molecular analysis revealed that our juvenile specimen was identical to S. longirostris adult from Japan (Kimura-2-parameter distance, d=0.002) based on mitochondrial DNA 16S ribosomal RNA region sequences 475 base pairs, and differed from its congeneric S. orientalis (d=0.199). The juvenile of S. longirostris has the following morphological traits: obvious dermal spots on both sides of the bases of the dorsal and anal fins; and peritoneum bluish black on its dorsalmost aspect. The juvenile of S. longirostris is also distinguished from S. orientalis in that they do not have a patch of melanophores above the abdominal cavity on the ocular-side. This is the first record of S. longirostris in Korea, and we propose a new Korean name "Gin-ko-bo-seop-seo-dae" for this species.

Reproductive Ecology and Spawning Behavior of the Natural Monumental and Endangered Species, Cobitis choii (Pisces: Cobitidae) in Geumgang (River), Korea (천연기념물이며 멸종위기종인 미호종개 Cobitis choii (Pisces: Cobitidae)의 번식생태 및 산란행동)

  • Myeong-Hun Ko;Il-Ro Lee;In-Chul Bang
    • Korean Journal of Ichthyology
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    • v.36 no.3
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    • pp.209-219
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    • 2024
  • A survey was conducted in 2011 to investigate the reproductive ecology and spawning behavior of the natural monumental and endangered species, Cobitis choii. C. choii exhibits sexual dimorphism with the development of lamina circularis on the second pectoral fin ray in males at one year old, facilitating easy differentiation between males and females. A total of 1,288 females and 881 males were collected from January to December, resulting in a sex ratio of 1 : 0.68. The spawning season was estimated to be from late June to early July (spawning peak from late June, with water temperatures ranging from 22 to 25℃), coinciding with a sharp decrease in the condition index. Gonadal maturity was observed with maturity indices of 17.5±2.11% for females and 2.9±0.46% for males, with fecundity of 2,444±838 eggs and egg size of 0.75±0.05 mm. Spawning behavior was induced by hormone injection (Human Chorionic Gonadotropin, HCG) in laboratory conditions. Experimental results revealed that males and females paired in a 1 : 1 ratio before spawning. Males pressed the abdomen of females using their lamina circularis to induce spawning, followed by immediate fertilization. Spawning behavior was repeated 15 to 25 (average 20) times per pair of males and females, and 80 to 120 eggs were spawned per time, and the total amount of spawned eggs were 2,500±250 on average.

A Comparative Anatomical and Histological Study of the Olfactory Organ of Amphidromous and Land-locked Sweet Fish, Plecoglossus altivelis(Osmeriformes, Osmeridae), in Seomjingang River System, Korea (섬진강 수계에 출현하는 양측회유성과 육봉형 은어 Plecoglossus altivelis 후각기관의 해부 및 조직학적 구조 비교 연구)

  • Min Jeong Choi;Jong Young Park
    • Korean Journal of Ichthyology
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    • v.36 no.3
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    • pp.230-239
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    • 2024
  • This study was carried out the anatomical and histological investigation of the olfactory organ on a land-locked and an amphidromous Plecoglossus altivelis in Deokam-ri, Shinpyeong-myeon, Imsil-gun, Jeollabuk-do and Daeduk-ri, Gojeon-myeon, Hadong-gun, Gyeongsangnam-do, August, 2021, Korea. The external morphology of the two types of P. altivelis was indistinguishable, featuring a pair of the elliptical anterior nostrils, the semicircular posterior nostrils, and the nasal flaps on the snout. The olfactory organ consisted of 20 to 22 olfactory lamellae forming a rosette structure in the nasal chamber. The secondary folds appeared on the lamellae. The histological results were also uniform. The sensory epithelium was a continuous type, consisting of olfactory receptor neurons, supporting cells, basal cells, cilia, and an unidentified cell. The non-sensory epithelium found only in the terminal part of lamellae, consist of stratified epithelial cells, basal cells, and mucous cells. For the olfactory organ between a land-lock type and an amphidromous type, no difference was observed in external and histological structure between amphidromous and land-locked type. However, it is considered that P. altivelis has higher olfactory sensitivity than other anadromous fish due to more number of olfactory lamellae and the presence of the secondary folds.