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http://dx.doi.org/10.7776/ASK.2009.28.7.661

Estimation of Structural Properties from the Measurements of Phase Velocity and Attenuation Coefficient in Trabecular Bone  

Lee, Kang-Il (강원대학교 물리학과)
Publication Information
The Journal of the Acoustical Society of Korea / v.28, no.7, 2009 , pp. 661-667 More about this Journal
Abstract
Trabecular-bone-mimicking phantoms consisting of parallel-nylon-wire arrays were used to investigate correlations of phase velocity and attenuation coefficient with structural properties in trabecular bone. Trabecular separation (Tb.Sp) of the 7 trabecular-bone-mimicking phantoms ranged from 300 to $900\;{\mu}m$ and volume fraction (VF) from 1.6% to 8.7%. Phase velocity and attenuation coefficient of the phantoms were measured by using a through-transmission method in water, with a matched pair of broadband unfocused transducers with a diameter of 12.7 mm and a center frequency of 1 MHz. Phase velocity and attenuation coefficient at 1 MHz decreased almost linearly with increasing Tb. Sp and increased almost linearly with increasing VF. The simple and multiple linear regression models with phase velocity and attenuation coefficient as independent vanables and Tb.Sp and VF as dependent variables demonstrated that the coefficients of determination for the prediction of VF were higher than those for the prediction of Tb.Sp. The results obtained in the trabecular-bone-mimicking phantoms consisting of parallel-nylon-wire arrays were consistent with those in human trabecular bone suggesting that the structural properties can be estimated from the measurements of phase velocity and attenuation coefficient in trabecular bone.
Keywords
Osteoporosis; Trabecular bone; Bone mineral density; Bone microarchitecture Ultrasound; Phase velocity; Attenuation coefficient;
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