• Title/Summary/Keyword: P3a

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The Study on the Risk Predict Method and Government Funds Supporting for Small and Medium Enterprises (로짓분석을 통한 중소기업 정책자금 지원의 위험예측력에 대한 연구)

  • Choi, Chang-Yeoul;Ham, Hyung-Bum
    • Management & Information Systems Review
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    • v.28 no.3
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    • pp.1-23
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    • 2009
  • Prior bankruptcy studies have established that bankrupt firm's pre-filing financial ratios are different from those of healthy firms or of randomly selected going concerns. However, they may not be sufficiently different from the financial ratios of other firms in financial distress to allow the development of a ratio-based model that predicts bankruptcy with reasonable accuracy. As the result, in the multiple discriminant model, independent variables divided firms into bankrupt firms and healthy firms are retained earnings to total asset, receivable turnover, net income to sales, financial expenses, inventory turnover, owner's equity to total asset, cash flow to current liability, and current asset to current liability. Moreover four variables Retained earnings to total asset, net income to sales, total asset turnover, owner's equity to total asset indicate that these valuables classify bankrupt firms and distress firms. On the other hand, Owner's Equity to borrowed capital, Ordinary income to Net Sales, Operating Income to Total Asset, Total Asset Turnover and Inventory Turnover are selected to predict bankruptcy possibility in the Logistic regression model.

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Effect of Fluoridated 10% Carbamide Peroxide on Enamel Surface Change and Whitening (불소를 첨가한 10% Carbamide Peroxide의 법랑질표면 변화와 미백효과)

  • Lee, Hye-Jin;Kim, Hyun-Dae;Kim, Min-Young;Kwon, Tae-Yub;Kim, Kyo-Han
    • Journal of dental hygiene science
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    • v.10 no.2
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    • pp.95-100
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    • 2010
  • The purposes of this study were to examine the effect of different fluoridated bleaching solution on the changes in physical and chemical characteristics of tooth. Forty-eight bovine incisors were divided into four groups to receive bleaching treatments, over a 14days period, as follows: no treatment; 10% carbamide peroxide (CP) bleaching; 10% CP containing 0.05% fluoride; and 10% CP containing 0.1% fluoride. All the specimens were highly polished and discolored with commercial COCK.Color and enamel changes were determined with colorimeter, microhardness tester, scanning electron microscope, atomic force microscopy. All the collected data were analyzed with one-way ANOVA. After the bleaching, bleached groups showed the color change(E*). Microhardness of 10% CP group decreased after tooth bleaching. But microhardness of containing fluoride bleached groups increased after tooth bleaching. Enamel surface of 10% CP bleached group showed any apparent morphology and roughness changes compared to the enamel which was stored in distilled water only. These results demonstrated that Fluoridated 10% Carbamide Peroxide have appreciable bleaching effect on bovine teeth and were not adversely affects enamel. Supporting influence of fluoride-containing bleaching solution on remineralization could be observed and further research must be carried out in various active environments to confirm these results clinically.

Distribution of Persistent Organic Pollutants (POPs) in Different Sizes of Particles in the Ambient Air of the Pyeongteak Area (평택지역 대기 중 먼지 입경별 잔류성유기오염물질 분포특성 연구)

  • Kim, Dong-Gi;Woo, Jung-Sik;Kim, Yong-Jun;Jung, Hye-Eun;Park, Ju-Eun;Cho, Duck-Hee;Moon, Hee-Chun;Oh, Jo-Gyo
    • Journal of Environmental Health Sciences
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    • v.46 no.2
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    • pp.192-203
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    • 2020
  • Objectives: The concentration distributions of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), dioxin-like polychlorinated biphenlys (dl-PCBs), and polycyclic aromatic hydrocarbons (PAHs) in fine particles were investigated to provide basic data on POP behavior and composition analysis. Methods: The concentrations of PCDD/Fs, dl-PCBs, and PAHs by particle size were evaluated for TSP, PM10, and PM2.5. Also, fine dust component analysis and factor analysis were performed to identify the source of PCDD/Fs. Results: The particle size distribution was found to account for 24.3% of >10 ㎛, 14.5% of 2.5-10 ㎛, and 61.2% of <2.5 ㎛. The average contributions of coarse particles (>2.5 ㎛) and fine particles (<2.5 ㎛) were PCDD/Fs 67%, dl-PCBs 66%, benzo (a) pyrene 83% and PAHs 84%, and the contributions of fine particles (<2.5 ㎛) were higher than coarse particles (>2.5 ㎛). However, the contributions of coarse particles increased in April to September with higher temperatures, while those of fine particles increased in February to March with lower temperatures. Conclusions: Low chlorinated (4Cl-5Cl) PCDD/Fs were more adsorbed compared to coarse particles due to the influence of pollutant migration from particulate to gas phase according to temperature rise, whereas high chlorinated (6Cl-8Cl) PCDD/Fs were more adsorbed compared to fine particles. PCDD/Fs sources were assessed to be major sources of emissions, such as incineration facilities and/or open burning.

Antioxidant Effect of HotWaterExtract of Muraenesox cinereus's Skin (갯장어껍질 열수 추출물의 항산화 효과)

  • Shin, Hyun-Jae;Kim, Yoon-Soo;Nam, Hyung-Gun;Na, Myung-Soon;Kim, Mi-Hye;Kang, Hyeong-Bong;Lee, Hee-Duck;Choi, Du-Bok;Choi, On-You;Cha, Wol-Suk
    • KSBB Journal
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    • v.26 no.1
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    • pp.27-32
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    • 2011
  • For the development of functional food and cosmetics using hot water extract of Muraenesox cinereus's skin, contents of vitamin, amino acid and element, and antioxidant activity were investigated. The results are shown as follows: among vitamins, A(0.21mg/100 g), C (78.12mg/100 g), $D_3$ (0.03 mg/100 g), E (1.97 mg/100 g) and Niacin (2.53mg/100 g) were detected, respectively.Mineral contents were an order of K > P > Na > Mg > Ca > Fe and Zn. Contents of total amino acids were an order of Pro > Gly > Arg > Glu > Phe > Ala. Especially, the sum of total amino acids was 27.17 mg/100 mL, which was about 4.0 fold higher than that of free amino acid. DPPH radical scavenging activity of hot water extract of M. cinereus's skin at 25 mg/mL was 63.5% and did not increase at above 50 mg/mL. Activities of antioxidant enzymes in the liver of ethanol-treated rats using hot water extract of M. cinereus's skin were investigated. Compared to control group, activities of ADH and GSH-px were decreased. In the case of CAT and SOD activity, they were increased. These results showed that the hot water extract of M. cinereus's skin can be applied to raw macterial for functional food and cosmetics.

Response of Ozone Sensitivity in Open-Pollinated Families of Pinus densiflora Seedlings (소나무 풍매차대묘(風媒次代苗)의 가계간(家系間) 오존에 대한 민감성(敏感性) 반응(反應))

  • Lee, Jae-Cheon;Oh, Chang-Young;Han, Sim-Hee;Kim, Jang-Su
    • Journal of Korean Society of Forest Science
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    • v.94 no.3 s.160
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    • pp.191-196
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    • 2005
  • This studies were conducted to compare ozone sensitivity among half-sib families of Japanese red pine (Pinus densiflora S. et Z.). 90 families were exposed in walk-in type chambers to charcoal-filtered air and 100 ppb ozone for 8 hours daily, 5 consecutive months. We surveyed the foliar injury, Relative DRC (diameter at root collar) growth and relative dry weight after fumigation. After 5 months of exposure, foliar injury ranged from 1.9% at tolerant group to 15.2% at sensitive group. Relative DRC growth rates showed increased 12% at tolerant group, but reduced 23% at sensitive group. Total dry weight increased 17% at tolerant group, otherwise reduced by 33% at sensitive group, relative to the control. The root biomass showed more sensitive than the other part biomass. On the basis of the results of these screening studies, families Kangwon 04, 16, 26, 27 and 73 were determined to be tolerant; Kangwon 40, 52, 83, Gyeonggi 01 and Gyeongbuk 20 to be sensitive to ozone. Considerable genetic variation in ozone responses occurred, as shown by differences in sensitivities among families and among groups. These results indicate that tolerant groups of P. densiflora exhibited a high degree of resistance to ozone pollution injury.

The Acupuncture Effect on Juvenile Smoking (청소년에 대한 금연침 효과)

  • Lim, Ho-Jea;Son, Chi-Hyoung;Lee, Won-Hui;Jang, Ha-Jeong;Seo, Joo-Hee;Jung, Kyung-Suk;Moon, Sung-Il
    • Journal of Acupuncture Research
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    • v.23 no.1
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    • pp.53-62
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    • 2006
  • Objectives : Because of the recent well-being syndrome, concerns about smoking cessation, as well as dietary improvement and exercise, are being increased. There are various methods for smoking cessation. Among them, recently acupuncture treatment is verified through diverse attempts. This research was conducted to examine the effects of acupuncture treatment especially on juvenile smoking cessation. Methods : From April 04 to Oct 04, this study had investigated 93 middle and high school students. 5 times of acupuncture treatment were given to each participant, and the survey was executed before and after each treatment. The acupuncture was treated to the ear alternately twice a week. The evaluation was taken before the treatment after the 1st treatment, and the 5th treatment with 6 questions of amount of daily smoking, desire to smoke, taste of smoking, subjective symptoms, smoking cessation proportion, Fagerstorm Tolerance Questionaire point. Results : Regarding amount of daily smoking, the significant tendency between before and after the treatment varied, but between the 1st and the 5th treatment, there was no difference. The 1st treatment had caused desire to smoke reduction in 46 students(49.5%), but the 5th treatment didn't have much effects on desire to smoke(43 persons; 46.2%). After treatment, 37.6% had no effect in taste of smoking, while the rest of them showed various reactions. Also, there were no difference of significant tendency between the 1st and 5th treatments. In respect to the amount of smoking, 70% of them achieved smoking cessation, or reduction in smoking, but about 25% of them showed no changes. Various subjective symptoms such as lethargy, decrease of appetite, headache were shown, and especially desire to smoke was shown pervasively. Regarding Fagerstorm Tolerance Questionaire point, the average of significant tendency in point after the treatment had decreased(3.1+-2.4 to 2.1+-2.1, p<0.0001). but for those students who had tried smoking cessation less than 5 times, Fagerstorm Tolerance Questionaire point had decreased significantly, but for the others who had tried smoking cessation more than 5times, there were no difference. Conclusion : In regard to 6 questions of amount of daily smoking, desire to smoke, taste of smoking, subjective symptoms, smoking cessation proportion, Fagerstorm Tolerance Questionaire point, various conclusion is drawn. These results suggest that acupuncture treatment on juvenile may have the tendency of smoking cessation.

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The Effect of Thermal Annealing and Growth of Cdln2S4 Single Crystal Thin Film by Hot Wall Epitaxy (Hot Wall Epitaxy(HWE)법에 의한 Cdln2S4 단결정 박막 성장과 열처리 효과)

  • 홍광준;이관교
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.15 no.11
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    • pp.923-932
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    • 2002
  • A stoichiometric mixture of evaporating materials for CdIn$\_$2/S$\_$4/ single crystal thin films was prepared from horizontal furnace. To obtain the single crystal thin films, CdIn$\_$2/S$\_$4/ mixed crystal was deposited on thoroughly etched semi-insulating GaAs(100) substrate by hot wall epitaxy(HWE) system. The source and substrate temperatures were 630 $\^{C}$ and 420 $\^{C}$, respectively. The crystalline structure of single crystal thin films was investigated by the photoluminescence and double crystal X-ray diffraction(DCXD). The carrier density and mobility of CdIn$\_$2/S$\_$4/ single crystal thin films measured from Hall effect by van der Pauw method are 9.01$\times$10$\^$16/ cm$\^$-3/ and 219 ㎠/V$.$s at 293 K, respectively. From the optical absorption measurement, the temperature dependence of energy band gap on CdIn$\_$2/S$\_$4/ single crystal thin films was found to be Eg(T) = 2.7116 eV - (7.74 $\times$ 10$\^$-4/ eV) T$\^$2//(T+434). After the as-grown CdIn$\_$2/S$\_$4/ single crystal thin films was annealed in Cd-, S-, and In-atmospheres, the origin of point defects of CdIn$\_$2/S$\_$4/ single crystal thin films has been investigated by the photoluminescence(PL) at 10 K. The native defects of V$\_$cd/, V$\_$s/, Cd$\_$int/ and S$\_$int/ obtained by PL measurements were classified as donors or accepters type. And we concluded that the heat-treatment in the S-atmosphere converted CdIn$\_$2/S$\_$4/ single crystal thin films to an optical p-type. Also, we confirmed that In in CdIn$\_$2/S$\_$4/GaAs did not from the native defects because In in CdIn$\_$2/S$\_$4/ single crystal thin films existed in the form of stable bonds.

Nitric Oxide on the MMP-2 expression by human gingival fibroblasts (치은섬유아세포의 MMP 발현에 대한 Nitric Oxide의 영향)

  • Shin, In-Sik;Yoon, Sang-Oh;Chung, Hyun-Ju;Koh, Jung-Tae
    • Journal of Periodontal and Implant Science
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    • v.33 no.2
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    • pp.277-288
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    • 2003
  • It has been suggested that increased number and activity of phagocytes in periodontitis lesion results in a high degree of reactive oxygen species (ROS) such as superoxide anion, hydrogen peroxide, nitric oxide and peroxynitrite. There are few reports on the relationship between ROS and MMPs expressions in gingival fibroblast. We studied to elucidate whether and how ROS, especially nitric oxide affects the MMP expression. Human gingival fibroblasts and HTl080 cells (human fibrosarcoma sell line as reference) were grown in DMEM supplemented with 10 mM HEPES, 50 mg/L gentamicin, and 10% heat inactivated fetal bovine serum with addition of various reactive oxygen species (ROS). Culture media conditioned by cells were examined by gelatin zymography. HT1080 cells expressed proMMP-2 and proMMP-9, but human gingival fibroblasts (HGF) produced only proMMP-2. Hydrogen peroxide upregulated MMP-9 expression in HT1080 cells, whereas in human gingival fibroblast SNP treatment showed marked increase in MMP-2 level compared to other ROS. These results suggest that the effects of ROS on MMPs expressions are cell-type specific. RT-PCR for MMP-2 and TIMP-2 m-RNA were performed using total RNA from cultured cells under the influence various kinase inhibitors. In HT1080 cells, treatment with FPTI III (Ras processing inhibitor) and LY294002 (PI3-kinase inhibitor) resulted in inhibition of MMP-2 and MMP-9 expressions, suggesting that Ras/P13-kinase pathway is important for MMPs expression in HT1080 cells. In gingival fibroblasts, treatment with FPTI III and PDTC (NF-kB inhibitor) showed marked decrease in MMP-2 regardless of the of SNP , suggesting that Ras/NF-kB could be the key pathway for NO-induced MMP-2 expression in gingival fibroblasts. This study showed that ROS, especially nitric oxide, could be the critical mediator of periodontal disease progression through control of MMP-2 expression in gingival fibroblasts possibly via Ras/NF-kB pathway.

Comparison of the prevalence of 4 periodontopathogens in supra-and subgingival plaque of young adults without periodontitis (치주질환이 없는 청년의 치은연상 및 치은연하 치면세균막에 존재하는 치주질환 관련 4종 세균의 분포 비교)

  • Jang, Hyun-Seon;Kim, Ji-Yeon;Kook, Joong-Ki;Yoo, So-Young;Kim, Hwa-Sook;Kim, Su-Gwan;Kim, Byung-Ock
    • Journal of Periodontal and Implant Science
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    • v.33 no.2
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    • pp.159-166
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    • 2003
  • The purpose of this study was to investigate and compare the frequence of 4 periodontal pathogens in the supra- and subgingival plaque in periodontally healthy subjects. Twenty adult individuals aged 22 to 28 years (mean age 23.65 years) participated in this study. All subjects had no pocket sites more than 3 mm deep, and the sites selected for sampling were all negative for bleeding. After drying and isolation of the sites with cotton rolls, supragingival plaque was sampled using sterile periodontal curette. Each plaque sample was placed in individual tubes containing 500 ml of 1X PBS. After removal of the supragingival sample and any remaining supragingival plaque, subgingival plaque samples were taken from the same sites using sterile curette and placed in similar individual tubes. Identification of 4 putative periodontal pathogens from the samples was performed by polymerase chain reaction based on 16S rDNA. Chi-square test was employed to identify significant explanatory variables for the presence of the 4 periodontal pathogens. The data show that Actinobacillus actinmycetemcomitans, Porphyromonanas gingivalis, Bacteroides forsythus, and Fusobacterium nucleatum occurred in 16.9%, 14.4%, 52.5%, and 80.6%, respectively. No significant differences were noted in the periodontal pathogens between supra- and subgingival plaques according to the kind of teeth. However, the incisors were at higher risk for harboring F. nucleatum (p <0.05). Conclusion: These results reveal that anaerobic periodontal pathogens can be detected in supragingival plaques. Supragingival plaque may function as a reservoir of peri-odotopathogens.

Cellular viability and genetic expression of human gingival fibroblasts to zirconia with enamel matrix derivative ($Emdogain^{(R)}$)

  • Kwon, Yong-Dae;Choi, Hyun-Jung;Lee, Heesu;Lee, Jung-Woo;Weber, Hans-Peter;Pae, Ahran
    • The Journal of Advanced Prosthodontics
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    • v.6 no.5
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    • pp.406-414
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    • 2014
  • PURPOSE. The objective of this study was to investigate the biologic effects of enamel matrix derivative (EMD) with different concentrations on cell viability and the genetic expression of human gingival fibroblasts (HGF) to zirconia surfaces. MATERIALS AND METHODS. Immortalized human gingival fibroblasts (HGF) were cultured (1) without EMD, (2) with EMD $25{\mu}g/mL$, and (3) with EMD $100{\mu}g/mL$ on zirconia discs. MTT assay was performed to evaluate the cell proliferation activity and SEM was carried out to examine the cellular morphology and attachment. The mRNA expression of collagen type I, osteopontin, fibronectin, and TGF-${\beta}1$ was evaluated with the real-time polymerase chain reaction (RT-PCR). RESULTS. From MTT assay, HGF showed more proliferation in EMD $25{\mu}g/mL$ group than control and EMD $100{\mu}g/mL$ group (P<.05). HGFs showed more flattened cellular morphology on the experimental groups than on the control group after 4h culture and more cellular attachments were observed on EMD $25{\mu}g/mL$ group and EMD $100{\mu}g/mL$ group after 24h culture. After 48h of culture, cellular attachment was similar in all groups. The mRNA expression of type I collagen increased in a concentration dependent manner. The genetic expression of osteopontin, fibronectin, and TGF-${\beta}1$ was increased at EMD $100{\mu}g/mL$. However, the mRNA expression of proteins associated with cellular attachment was decreased at EMD $25{\mu}g/mL$. CONCLUSION. Through this short term culture of HGF on zirconium discs, we conclude that EMD affects the proliferation, attachment, and cell morphology of HGF cells. Also, EMD stimulates production of extracellular matrix collagen, osteopontin, and TGF-${\beta}1$ in high concentration levels. CLINICAL RELEVANCE. With the use of EMD, protective barrier between attached gingiva and transmucosal zirconia abutment may be enhanced leading to final esthetic results with implants.