• Title/Summary/Keyword: P34

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Lymphangiogenic and Angiogenic Microvessel Density in Chinese Patients with Gastric Carcinoma: Correlation with Clinicopathologic Parameters and Prognosis

  • Cao, Fang;Hu, Yong-Wei;Li, Ping;Liu, Ying;Wang, Kuo;Ma, Lei;Li, Peng-Fei;Ni, Can-Rong;Ding, Hou-Zhong
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4549-4552
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    • 2013
  • The incidence of gastric cancer worldwide, and in particular in developing countries, has shown a marked increase. Poor prognosis of gastric cancer patients occurs due to the rapid metastasis of the disease via the lymphatic and blood vessels. The aim of this study was to investigate the expression and the clinical significance of D2-40 and CD34 in human gastric cancer. D2-40 and CD34 expression wasdetected in 1,072 cases of Chinese patients with gastric carcinoma using immunohistochemistry. The lymphatic vessel density (LVD) and microvessel density (MVD) were calculated and analyzed and the correlation with the clinicopathological factors and prognosis was determined. The LVD and MVD of the gastric cancer cases were significantly higher compared to those of normal tissues (P < 0.05). The expression of D2-40-LVD and CD34-MVD in the malignancies were positively related to the age, tumor size, invasion depth, lymphatic metastasis and pathological tumor-node-metastasis (pTNM) (P < 0.05); However, no statistically significant difference was identified between them with the patient gender (P > 0.05). Up-regulation of D2-40 and CD34 expression was significantly correlated with the poor survival rate in univariate and multivariate analyses. The LVD marked by D2-40 and the MVD marked by CD34 were positively correlated to the clinicopathological factors of the malignancies and may play important role in the development and progression of gastric cancer.

Influential factors of Health-related Quality of Life of Women Merchants at Traditional Markets (전통시장 여성상인의 건강관련 삶의 질에 미치는 영향요인)

  • Bae, Young Sil
    • Journal of Korean Public Health Nursing
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    • v.34 no.3
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    • pp.355-367
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    • 2020
  • Purpose: This study aims to identify factors influencing the health-related quality of life among women merchants at traditional markets. Methods: Participants in this cross-sectional descriptive study included 121 women merchants. Data were collected from May 01 to June 30, 2019 using the patient health questionnaire-9 (PHQ-9), psychosocial well-being index-short form (PWI-SF), subjective health status, and HRQoL. Selected data were analyzed using descriptive statistics, Pearson's correlation coefficient, and stepwise multiple regression by applying the SPSS/WIN program 22.0. Results: The HRQoL was significantly different by age (F=5.87, p=.001), education (F=2.98, p=.022), working period (F=4.70, p=.004), exercise (t=2.20, p=.030), chronic disease (t=-2.57, p=.011), BMI (F=5.04, p=.008), depression (F=4.70, p=.004), stress (F=7.82, p<.001), and subjective health status (F=7.91, p=.001). Factors influencing the HRQoL for women merchants included BMI (β=-.35, p<.001), subjective health status (β=.33, p<.001), and stress (β=-.18, p=.021). The explanation power of this regression model was 29.8% (F=5.51, p<.021). Conclusion: BMI, subjective health status, and stress affect the HRQoL of the subjects evaluated. Therefore, there is a need for health management programs that may decrease stress, control the BMI, and improve the subjective health status of women merchants at traditional markets.

A Convergence Study on the Effect of Self-directed Practice based Peer-tutoring on Performance, Confidence and Self-efficacy of Core Nursing Skills in Nursing Students (동료 교수학습 기반 자율실습이 핵심기본간호술 숙련도, 수행자신감 및 자아효능감에 미치는 효과에 관한 융합연구)

  • Koo, Heesun
    • Journal of the Korea Convergence Society
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    • v.10 no.12
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    • pp.453-463
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    • 2019
  • The purpose of study was the non-equivalent control group pretest-posttest design to test the effect of self-directed nursing practice based peer-tutoring of same sophomore, on the level of confidence, performance and self-efficacy of core nursing skills in nursing students. The subjects were 68 nursing students in K City from May 1th to June 12th in 2019. The participants were shared into the peer tutoring practice group (experimental group, n=34) and the lecturer guided practice group (control group, n=34). The results of study, the experimental group scored significantly higher on the foley catheterization performance (t=11.60, p<.001), confidence (t=4.123, p<.001) and wearing protection equipment performance (t=5.91, p<.001), confidence (t=4.24, p<.001) and enema performance (t=2.82, p=.008), confidence (t=2.09, p=.044) and self-efficacy (t=4.52, p<.001) than control group. Therefore, the results justified that self-directed nursing practice based peer-tutoring could be effective in improving the performance, confidence and self-efficacy of core nursing skills in nursing students. Based on this, I suggest the study that examines the effects of peer-tutoring by applying it to various majors.

Convergence Factors Affecting Aggression of College Students in a City -Focusing on Life Stresses- (일개 도시 대학생의 공격성에 영향을 미치는 융합적 요인 -생활스트레스 중심으로-)

  • Ha, Tae Hi
    • Journal of Digital Convergence
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    • v.17 no.5
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    • pp.319-326
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    • 2019
  • This study was examined the influences of life stress on the aggression of college students. For this purpose 262 college students in Daegu completed the related study. Data were collected from September 5 to September 7, 2017. Collected data were analyzed using IBM SPSS 25.0. The major findings were as follow; 1) The life stress of the subject was the highest in study problem. 2) There were significant differences in aggression according to gender(t=4.43, p<.001) and major(F=13.66, p<.001). 3) The aggression was positively correlated with interpersonal problem(r=.49, p<.001), study problem(r=.34, p<.001), economic problem(r=.34, p<.001), future problem(r=.35, p<.001) and value problem(r=.31, p<.001). 4) The factors affecting to aggression were interpersonal problem, science and engineering, and study problem, and these factors accounted for 30% of aggression. Through this study, it was possible to grasp the degree of life stress and the influencing factors of aggression of college students. And the significance of this study is to suggest the direction of program for the management of aggression of college students.

Experimental Study of Lonicerae Caulis and Bee-venom Acupuncture on the Rheumatic Pathologic Model Induced by Adjuvant in Rats (인동등과 봉독약침이 Adjuvant 투여로 유발된 류마토이드 병태모델에 미치는 실험적 연구)

  • Bae, Myung-Hyun;Yeam, Seung-Ryong;Kim, Jin-Hee;Kwon, Young-Dal
    • Journal of Korean Medicine Rehabilitation
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    • v.25 no.1
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    • pp.17-26
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    • 2015
  • Objectives This study was carried out to investigate the experimental effects of Lonicerae Caulis and Bee-venom Acupuncture in Yanglingquan (陽陵泉, GB34) that have clinical efficacy in the Rheumatoid Arthritis. Methods Materials of present study are Lonicerae Caulis Extracts (LCE), Bee-Venom Acupuncture (BVP), Sprague-dawley rats (250 g or so, ♂), and various kinds of needing experimental studies. We measured several experimental items of the rats with the arthritis induced by Freund's complete adjuvant (0.2 ml/kg), such as body weight, rate of paw edema, analgesic effect by hot plate method, WBC, TNF-${\alpha}$ cytokine and IL-10 cytokine. Rats were divided into four groups; Normal group that was treated with normal saline 1.0 ml (o.p) and $15{\mu}l/kg$ (GB34) to normal rats, Control group that was treated with normal saline 1.0 ml (o.p) and $15{\mu}l/kg$ (GB34) to pathologic model rats induced by Freund's complete adjuvant 0.2 ml/kg, Experimental group A that was treated with LCE 1.0 ml (o.p) and normal saline $15{\mu}l/kg$ (GB34) to pathologic model rats induced by Freund's complete adjuvant 0.2 ml/kg and Experimental group B that was treated with LCE 1.0 ml (o.p) and BVP $15{\mu}l/kg$ (GB34) to pathologic model rats induced by Freund's complete adjuvant 0.2 ml/kg, and the experiment took over after 28 days. The results were analysed using SPSS for windows 12.0. Results Experimental group A showed the increase in body weight, paw licking times and IL-10 cytokine compared to Control group. Also it was decreased in rate of paw edema, WBC, and TNF-${\alpha}$ cytokine compared with Control group. Experimental group B showed the increase in body weight, paw licking times, and IL-10 cytokine compared to Control group, and showed the decrease in rate of paw edema, WBC and TNF-${\alpha}$ cytokine compared to Control group. Especially TNF-${\alpha}$ cytokine and rate of paw edema were accepted statistical significance compared with Control group. Conclusions It is suggested that Lonicerae Caulis (o.p) and Bee-venom Acupuncture (GB34) can be used in the treatment of rheumatoid arthritis.