• Archives of Pharmacal Research
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• v.2 no.2
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• pp.145-151
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• 1979

The carpophores of three Korean mushrooms, Coriolus versicolor, Pleurotus ostreatus and Lentinus edodes were respectively extracted with hot water and the extracts were dialyzed through Visking tube. They were found to exert an antitumor activity against sarcoma-180 implanted in mice. Especially, the inhibition ratio of the extract of Coriolus versicolor (100 mg/ Kg.i.p) was almost 100% . But all the extracts did not affect the growth of leukemia L517Y cells in vitro. Therefore these facts indicate that the extracts appear to stimulate cell-mediated immunity.

• Research in Community and Public Health Nursing
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• v.12 no.3
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• pp.828-837
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• 2001

Purpose: This study was aimed to identify the difference of the self-efficacy and the health promoting behaviors between obese and normal-weight middle school students. Method: Data were collected from a convenient sample of 360 middle school students (180 normal-weight students and 180 obese students) in Pusan from November 22nd to December 20th. 2000. based on self-report questionnaires. The following instruments were used in the study after being reconstructed by the researcher with the consultation of experts and the literature review: General Self Efficacy Scale(Sherer et al.. 1982). and Health Promoting Lifestyle Profile (Walker. Sechrist & Pender. 1987). The data were analyzed with descriptive statistics, chi-square test. and t-test and Pearson's correlation coefficient. Results: 1. There were significant differences in father's obesity (p=.014) mother's obesity (p= .007), sibling's obesity (p=.00l), and school record (p=.001) between obese and normal-weight students. 2. There were statistically significant differences in the score of self-efficacy between the obese and normal-weight students (p=.0001) 3. There were statistically significant differences in health promoting behavior (p= .000) and in six sub-i terns: personal relationship (p =.000), exercise (p=.001), responsibility for health (p=.003), stress management (p = .015), self-actualization (p =.043) between the obese and normal weight students. 4. There were very statistically significant negative correlations between obesity and the self-efficacy (r=-.19. p<.001), health promoting behavior (r=-.18. p<.001), specifically personal relationship(r=-.20. p<.001), stress management (r=-.12. p<.05), responsibility for health (r=-.15. p<.01), and self-actualization (r=-.14. p<.01). Conclusion: According to the above results it is concluded that self-efficacy and health promoting behavior influence the obesity of middle school students. Therefore I recommend adding programs that can lead to improve self-efficacy and health promoting behavior to the obesity prevention programs for middle school students.

• Korean Journal of Food Science and Technology
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• v.45 no.2
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• pp.180-190
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• 2013

The purpose of this study was to determine the optimal amount of 2 ingredients, i.e., black barley flour ($X_1$), and olive oil ($X_2$), for the production of white pan bread from black barley flour. The experiment was designed according to the central composite design of response surface methodology, which showed 10 experimental points, including 2 replicates for black barley flour and olive oil. Significant differences were found in the results of the physical and mechanical properties analysis of each sample, including weight (p<0.05), volume (p<0.01), specific loaf volume (p<0.01), color L (p<0.01), color a (p<0.001), color b (p<0.05), hardness (p<0.001), springiness (p<0.01), cohesiveness (p<0.01), gumminess (p<0.001) and chewiness (p<0.05). Significant differences in the sensory measurements were observed in color (p<0.01), appearance (p<0.01), texture (p<0.05), taste (p<0.05) and overall quality (p<0.05). The optimum formulation, which was calculated using the numerical and graphical methods, was determined to be 18.00% black barley flour and 1.80% olive oil.

• The Korean Journal of Food And Nutrition
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• v.8 no.4
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• pp.301-306
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• 1995

This study was carried out to find out rice quality of Chucheongbyeo cultivated on Gyeonggj and other province. Rice type, color difference, amylograph of milled rice and texturograph of cooked rice were not significant between two cultivated region. And fat, protein, Mg and Ca in milled rice were not significant but p, K and Na were significantly different at l% the level between them as 2, 210~2, 420ppwt 1, 304~1, 538ppm and 212~236ppm in Gyeonggi province cultivated rice, and 2, 130~2, 180ppm, 1, 133~1, 180ppm and 197~217ppm in other province, respectively. Also amylose content, alkali distribution and gel consistency were not significant between them.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2002.11a
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• pp.180-180
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• 2002

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.180-180
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• 1994

Farnesyl protein transferase는 Ras precursor의 C-terminal에 있는 cystein residue에 farnesyl group을 결합시키는 효소다. 이 효소를 bovine testis에서 30-50% ammonium sulfate fractionation, DEAE-sephacel ion exchange, Sephacryl s-300 gel filtration, hexapeptide(KKCVIM) affinity chromatography를 통해 30000배로 분리하였다. 분리된 효소는 gel filtration시 약 100kDa으로, SDS-polyacrylamide 전기영동시 50kDa의 인접한 두 bands로 나타났고 이것은 $\alpha$, $\beta$ subunits으로 생각되었다. $\alpha$ subunit을 encoding하는 RAM2 유전자를 site directed mutagenesis로 145번의 histidine을 aspartate로, 140번의 aspartate를 asparagine 으로 바꾸었더니 optimal pH와 $K_{m}$ 값이 변했다. Diethyl pyrocarbonate로 histidine residues를 chemical modification시켰을때 효소의 활성이 저하되었다. 145번 histidine이 aspartate로 바뀐 돌연변이효소에서 비교적 느리게 활성이 저하되므로 145번 histidine이 이 효소의 active site에 있을것으로 추측된다.

• Korean Journal of Food Science and Technology
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• v.10 no.2
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• pp.258-262
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• 1978

Proximate composition, minerals and fatty acid in dried chicory root (moisture content 7.0%) are analyzed and subsequent results are as follows: Crude protein, crude fat, crude fiber, total sugar and ash content in chicory root are 8.6%, 1.6 %, 6.9%, 58.5% and 4.2%, respectively. Mineral content of Ca, P, Fe, Mg and Si in the root are 1,560, 180, 10,600 and 180 mg%, respectively. Other minerals such as K, Na, Al, Zn, Ag, Cu and Ti are also determined. Unsaturated fatty acid content in total fat of the root is 65.4%, Particularly high in linoleic acid. Uridine-5'-diphospho-glucose, as sole nucleotide-sugar in the root, was detected.

• Archives of Pharmacal Research
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• v.8 no.1
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• pp.42-44
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• 1985

Polysaccharides were isolated with alkaline extraction method from twelve pharmaceutical plants, which have been used against the various tumors in the oriental herb medicine, and examined for their antitumor activities. When the polysaccharides were administered i. p. at the dose of 10mg/kg/day for ten consecutive days to the male ICR mice, which had been implanted with $1{\times}10^{6}$ cells of sarcoma 180 twentyfour hours before the first injection of polysaccharides, those from Forsythia Corea, Curcuma, Zedoaria, Albizzia Julibrissin, Prunuts Persica, Foeniculum Vlugare and Daphne Pseudogenkwa showed inhibition ratios of 88.0%, 61.1%m 73.0%, 72.8% 55.1% and 71.7%. The significant prolongation of life span was observed only in the case of Forsythia Corea (18.1%). Other six polysaccharide fractions from Olibanum, Lonicera Japonica, Rheum Coreanum, Scirpus Maritimus, Gleditchia Officinalis and Brassica Juncea showed negligible inhibition ratios.

• Korean Journal of Optics and Photonics
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• v.9 no.2
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• pp.117-122
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• 1998

We modeled the dynamic switching behavior of a bistable twisted-nematic liquid crystal cell by employing the Berreman's backflow model. Although viscosity paramenters of the liquid crystal material are not known, numerically calculated optical switching characteristics shows good agreement with experimental results. With this model we also have shown that bistable switching can be observed in a $180^{\circ}$ twisted cell only when two alignment layers are rubbed in the opposite direction.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.180-180
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• 2002

The potential allergenicity of the transgene products in genetically modified organisms (GMOs), has been an important issue. As a part of the risk assessment of GMOs, we investigated the physicochemical stability and the immunogenicity of food allergens to determine their allergenicity.(omitted)