• Archives of Pharmacal Research
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• v.27 no.1
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• pp.31-34
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• 2004

The electrochemical behavior of doxorubicin hydrochloride was investigated by cyclic voltammetry (CV) and square wave voltammetry (SWV). From CV and SWV studies of doxorubicin hydrochloride in the acetate buffers of various pH values, it was found that protons were involved in the reduction of the antibiotic at the $H^+/e^$- ratio at one ( $\DeltaEp/pH =-53 ∼ -61 mV at 23^{\circ}C$), proposing the electrochemical reduction of the quinone moiety in its anthraquinone aglycone. Its electrochemical behavior was pseudo-reversible in the acetate buffer of pH 3.5 by exhibiting the well-defined single cathodic and anodic waves and the ratio of $lp^a/lp^c$ at approximately one over the scan rates of 10∼100 mV/s. Fast and sensitive SWV showing a single peak of doxorubicin has been applied for its quantitative analysis using an acetate buffer of pH 3.5. A linearity was obtained when the peak currents (lp) were plotted against concentrations of doxorubicin in the range of $5.0\times10^{-7} M∼1.0\times10^{-5}$M with a detection limit of $1.0\times10^{-7}$ M.

• Journal of the Korean Geophysical Society
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• v.3 no.3
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• pp.193-200
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• 2000

The attenuation characteristics($Q^{-1}$) are important factors representing the physical properties of the Earth interiors, and are essential for the quantitative prediction of strong ground-motion. Based on 156 earthquakes including 76 single-station record on the seismic station located Deok-jung Ri, southeastern Korea, we made the simultaneous measurement of P and S wave attenuation($Q_P^{-1}\;and\;Q_S^{-1}$) by means of extended coda-normalization method. Estimated $Q_P^{-1}\;and\;Q_S^{-1}$ decreased from $1{\times}10^{-2}\;and\;9{\times}10^{-3}$ at 1.5 Hz to $6{\times}10^{-4}\;and\;5{\times}10^{-4}$ at 24 Hz, respectively. This can be expressed by $Q_P^{-1}=0.01\;f^{-1.07}\;and\;Q_S^{-1}=0.01\;f^{-1.03}$ which indicate strong frequency dependence.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.31 no.3
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• pp.115-128
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• 2019

In this study, a probabilistic model for the estimation of yearly workable wave condition period for offshore operations is developed. In doing so, we first hindcast the significant wave heights and peak periods off the Ulsan every hour from 2003.1.1 to 2017.12.31 based on the meteorological data by JMA (Japan Meterological Agency) and NOAA (National Oceanic and Atmospheric Administration), and SWAN. Then, we proceed to derive the long term significant wave height distribution from the simulated time series using a least square method. It was shown that the agreements are more remarkable in the distribution in line with the Modified Glukhovskiy Distribution than in the three parameters Weibull distribution which has been preferred in the literature. In an effort to develop a more comprehensive probabilistic model for the estimation of yearly workable wave condition period for offshore operations, wave height distribution over the 15 years with individual waves occurring within the unit simulation period (1 hour) being fully taken into account is also derived based on the Borgman Convolution Integral. It is shown that the coefficients of the Modified Glukhovskiy distribution are $A_p=15.92$, $H_p=4.374m$, ${\kappa}_p=1.824$, and the yearly workable wave condition period for offshore work is estimated to be 319 days when a threshold wave height for offshore work is $H_S=1.5m$. In search of a way to validate the probabilistic model derived in this study, we also carry out the wave by wave analysis of the entire time series of numerically simulated significant wave heights over the 15 years to collect every duration periods of waves the height of which are surpassing the threshold height which has been reported to be $H_S=1.5m$ in the field practice in South Korea. It turns out that the average duration period is 45.5 days from 2003 to 2017, which is very close to 46 days from the probabilistic model derived in this study.

• Journal of Convergence for Information Technology
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• v.10 no.8
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• pp.203-212
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• 2020

The purpose of this study was to investigate the effects of cognitive rehabilitation programs using Virtual Reality(VR) content on the daily living abilities such as cognitive abilities, depression, and upper extremity functions of the elderly. The study group analyzed the effectiveness by separating the experimental group, which is the virtual reality cognitive rehabilitation application group, and the control group, the universal cognitive stimulation program application group. As a result of the study, the MMSE-K score improved by 13.0% in the experimental group and 2.3% in the control group. The improvement in each area of the experimental group was found to be 3.1% MBI, 7.1% MFT(Rt.), 3.5% MFT(Lt.), and 25.4% K-GDS. As a result of comparing the pre-post score change between each group, there was a significant difference between groups in daily living ability (p<.001) and MFT(Rt.)(p<.01). In addition, as a result of comparing the changes in absolute alpha waves to confirm the degree of depression through brain waves, there was no statistically significant difference. However, in the experimental group, it was confirmed that the average value increased to a positive value. This study is an experiment to verify the effectiveness of the cognitive rehabilitation program using virtual reality contents, and suggests a new intervention method to maintain and improve the daily life ability, cognitive function, depression and upper extremity function of the elderly.

• Journal of Ocean Engineering and Technology
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• v.33 no.1
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• pp.1-9
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• 2019

This paper considers a numerical assessment of the self-propulsion performance of a damaged ferry carrying cars in irregular waves. Computational fluid dynamics(CFD) simulations were performed to see whether the ferry complied with the Safe Return to Port (SRtP) regulations of Lloyd's register, which require that damaged passenger ships should be able to return to port with a speed of 6 knots (3.09 m/s) in Beaufort 8 sea conditions. Two situations were considered for the damaged conditions, i.e., 1) the portside propeller was blocked but the engine room was not flooded and 2) the portside propeller was blocked and one engine room was flooded. The self-propulsion results for the car ferry in intact condition and in the damaged conditions were assessed as follows. First, we validated that the portside propeller was blocked in calm water based on the available experimental results provided by KRISO. The active thrust of starboard propeller with the portside propeller blocked was calculated in Beaufort 8 sea conditions, and the results were compared with the experimental results provided by MARIN, and there was reasonable agreement. The thrust provided by the propeller and the brake horsepower (BHP) with one engine room flooded were compared with the values when the engine room was not flooded. The numerical results were compared with the maximum thrust of the propeller and the maximum brake horse power of the engine to determine whether the damaged car ferry could attain a speed of 6 knots(3.09 m/s).

• Journal of Information Technology Applications and Management
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• v.14 no.4
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• pp.43-59
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• 2007

The purpose of the study was to examine the effectiveness of Neuro Feedback training by observing the pre and post brainwave measurement results of about 50 (experimental group 25. comparative group 25) subjects who have shown psychological difficulties in studying. attention deficit, and personalities. The study took place at Neuro Feedback training Center B. in between the months of July 2006 and May 2007. The methodology involved in the study included the Coloring Analysis Program of the Brain Quotient Test. As the brain waves are adjusted by timeseries linear analysis. the brain function quotients can reflect the functional states of the brain. Through the test, three parameters relaxation, attention and concentration-were initially measured for one minute each and the lowest parameter out of the three was selected as the training mode or improvement target. The training took place two or three times a week. for about 40 to 60 minutes per session. Because the clients have come to the training center at different times. the researcher sampled the results of only those who had attended more than 30 training sessions. The tool used to measure the psychological reaction was POMS (Profile of Mood State). while the tool used to measure the emotional and attention-deficit characteristics was the Amen Clinic ADD Type questionnaire. Hypothesis testing included t-test. The result of the study showed the Theta: SMR ratio of (left)p = .013. (right) p = .019. The result also confirmed the differences of both ATQ(left) p = .011. (right)p = .030 and SQ(left) p = .017. (right) p = .022. The result confirmed of emotional p = .000. attention-deficit characteristics p = .000. The result of the study suggest Neuro Feedback technique's possibility in positively affecting the subjects' mental state and attention-deficit characteristics.

• Journal of the Korean Chemical Society
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• v.18 no.2
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• pp.110-116
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• 1974

Reduction of chromate ion at the Pt-electrode was investigated in neutral unbuffered solutions, in buffered solutions of pH between 8 and 10, and in strongly alkaline medium. In buffered solutions of pH between 8 and 10, the number of electrons transfered in the reduction of chromate ion increased progressively with increasing pH. When chromate ion was reduced in 0.2 N sodium hydroxide medium the following mechanism was suggested: $CrO_4^=+H_2O+2e{\rightarrow}CrO_3^=+2OH^-,\;CrO_3^=3H_2O+e{\rightarrow}Cr(OH)_3+3OH^-$ When tetramethylammonium hydroxide (pH=13.5) was used as the supporting electrolyte, a second wave indicated strong adsorption. In unbuffered solutions of 0.1 N potassium chloride the linear sweep voltammogram consists of three or four distinct waves depending on the initial voltage and the voltage sweep rates, but the first wave was difficult to explain as a diffusion controlled wave.

• Proceedings of the KSRS Conference
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• v.2
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• pp.973-976
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• 2006

The oscillations of the Caspian Sea level represent a result of mutually related hydrometeorological processes. The change in the tendency of the mean sea level variations that occurred in the middle 1970s, when the long-term level fall was replaced by its rapid and significant rise, represents an important indicator of the changes in the natural regime of the Caspian Sea. Therefore, sea level monitoring and long-term forecast of the sea level changes represent an extremely important task. The aim of this presentation is to show the experience of application of satellite altimetry methods to the investigation of seasonal and interannual variability of the sea level, wind speed and wave height, water dynamics, as well as of uplift of the Earth’s crust in different parts of the Caspian Sea and Kara-Bogaz-Gol Bay. Special attention is given to estimates of the Volga River runoff derived from satellite altimetry data. The work is based on the 1992-2005 TOPEX/Poseidon (T/P) and Jason-1 (J-1) data sets.

• Economic and Environmental Geology
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• v.21 no.1
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• pp.97-106
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• 1988

The purpose of this study is to collect basic data which are prerequisite for quantitative analysis of coal logging data. The study involves laboratory measurements of physical properties such as seismic velocities (P,S-waves), resitivity and density of domestic and imported foreign coals. The relationships between these properties were analyzed by using cross-plots. Correlation between the physical properties of coal and the results of chemical analysis (calorie, fixed carbon, ash, moisture, volatile matter and sulfur contents) was also studied to obtain ideas about coal quality analysis using logging data. Summarized results are as follows: 1. $V_P$ is exponentialy related to $V_S$. And the average value of $V_P$ is about l.8 times as large as $V_S$. 2. Since coal has very low density compared with surrounding sedimentary rocks, density logging is appeared to be the best method for identifying coal seams and evaluating their qualities. 3. For the case of domestic coals, the ash contents and calorie show a perfect inverse relationship. Since the density increases as increase of ash content with a well-defined functional form, the ash content of domestic coals can be estimated by density measurements. 4. Because of low ash content, low density and high resistivity, foreign coals and domestic lignites are easily distinguished from domestic coals.

• Journal of The Korean Astronomical Society
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• v.40 no.4
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• pp.179-182
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• 2007

Dynamical friction plays an important role in reducing angular momenta of objects in orbital motions. While astronomical objects usually follow curvilinear orbits, most previous studies focused on the linear-trajectory cases. Here, we present the gravitational wake due to, and dynamical friction on, a perturber moving on a circular orbit in a uniform gaseous medium using a semi-analytic method. The circular orbit causes the density wakes to bend along the orbit into asymmetric configurations, resulting in the drag forces in both opposite (azimuthal) and lateral (radial) directions to the perturber motion, although the latter does not contribute to the orbital decay much. For a subsonic perturber, the bending of a wake is only modest and the resulting drag force in the opposite direction is remarkably similar to the linear-trajectory counterpart. On the other hand, a supersonic perturber is able to overtake its own wake, possibly multiple times, creating a high-density trailing tail. Despite the dramatic changes in the wake morphologies, the azimuthal drag force is in surprisingly good agreement with the formulae of Ostriker for the linear-trajectory cases, provided $V_pt=2R_p,\;where\;V_p\;and\;R_p$ are the velocity and orbital radius of the perturber, respectively.