• Title/Summary/Keyword: P-loop

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Modified Fontan Procedure for Single or Dominant Right Ventricle (우세우심실 또는 우단심실증에서의 변형 Fontan 수술)

  • 백완기
    • Journal of Chest Surgery
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    • v.24 no.3
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    • pp.310-321
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    • 1991
  • Between April 1986 and September 1990, 34 patients with a single or dominant right ventricle underwent modified Fontan procedure for definite palliation in Seoul National University Children`s Hospital. Their age at operation ranged from 8 months to 14 years [Mean 5.5 years]. The ventricular chamber was solitary and of indeterminate trabecular pattern in 6 patients. 28 patients had posteriorly located rudimentary chamber, all of which were trabecular pouches having no communication with outlet septum. The patterns of atrioventricular connection were common inlet[9], double inlet [11], left atrioventricular valve atresia [12] and right atrioventricular valve atresia with L-loop [2]. Pulmonary outflow tracts were atretic in 7 patients and stenotic in 26 patients. Major associated anomalies included anomalous systemic venous drainage [15], dextrocardia [12] and total anomalous pulmonary venous connection[3]. Shunt operations were previously performed in 13 patients and pulmonary artery banding and atrial septectomy in 1 patients. Surgery included intraatrial baffling in 26 patients, bidirectional cavopulmonary shunt in 13 patients, atrioventricular valve obliteration in 3 patients and atrioventricular valve replacement in 3 patients. Central venous pressure measured postoperatively at intensive care unit ranged from 18cm H2O to 28cm H2O [mean 23.2cm H2O]. Hospital mortality was 35.3% [12/34], all died out of low output syndrome. Suspected causes of low output syndrome include ventricular dysfunction [8], hypoplastic or tortuous pulmonary artery [2] and elevated pulmonary vascular resistance [2]. 19 patients had 31 major complications including low output syndrome [18], arrhythmia [4], acute renal failure [3] and respiratory failure [3]. Mortality rate was significantly higher in the groups receiving intraatrial baffling and AV valve replacement respectively [p<0.05]. 20 patients were followed up postoperatively with the mean follow-up period 15.0$\pm$11.6 months. There were no late death and follow-up catheterization was performed in 10 patients. Mean right atrial pressure was 15.4$\pm$6.8mmHg and ventricular contraction was reasonable in all but one case. Thus, Fontan principle can be applied successfully to all the patients with complex cardiac anomaly of single ventricle variety and better results can be anticipated with judicious selection of patient and improvement of postoperative care.

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철분강화 유제품 제조 및 생이용성 평가연구

  • 김윤지
    • Proceedings of the Korean Journal of Food and Nutrition Conference
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    • 2000.05a
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    • pp.9-11
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    • 2000
  • 국민의 영양상태가 크게 향상되어왔고 일부에서는 영양과잉과 운동부족으로 인한 비만에 대한 우려가 고조되고 있지만 최근에도 유아나 성장기 어린이들의 철분부족상태에 대한 문제점이 제기되고 있다. 외국에서는 철분 필요량이 높은 성장기 어린이나 유아들에게 영양학적 품질을 개선한 철분강화제품을 공급하기 위하여 이에 대한 연구가 오래 전부터 진행되어왔으나 여러 실험자에 의하여 행해진 실험조건, 사용된 철분염의 종류가 달라서 정확한 비교평가를 하기에는 미흡하다고 사료된다. 여러 가지 식품에서 특히 우유는 영양학적으로 완전식품이라고 하지만 철분은 거의 함유하고 있지 않아서 효과적으로 철분을 강화할 수 있는 기술은 국민영양개선 효과면에서 매우 유용하다고 사료된다. 본 연구에서는 식품첨가물로서 사용되고 있는 철분염 11종을 우유에 100 ppm수준으로 첨가하고 4$^{\circ}C$에서 저장하면서 pH, 지방산패도, 색도변화를 평가하여 우유에 사용하기 적합한 철분염을 1차적으로 선정하였다. 품질평가 결과를 종합하여 분석할 때 ferric citrate, ferric ammonium citrate, ferrous lactate가 철분강화우유 제조에 적합한 것으로 평가하였다. 또한 지금까지 철분강화식품에 일반적으로 자주 사용하고 있는 ferrous sulfate는 우유에 적합하지 않은 것으로 나타났으나 비교치로 사용하기 위하여 다음 실험에 사용하였다. 이상에서 screening된 철분염을 첨가한 우유를 HTST, LTLT으로 각각 살균하고 저장하면서 품질을 평가한 결과 HTST법이 LTLT법보다 PH, 지방산패도, 색도변화에서 나쁜 것으로 평가되었고, 철분염 종류에 따른 차이는 LTLT, HTST법에서 ferrous lactate가 우수한 것으로 나타났다. 본 연구에서 사용된 철분염 가운데에서는 ferrous lactate, ferric citrate가 유제품에 사용하기에 적합한 것으로 나타났다. 생이용성을 평가하기 위하여 우유에서 low molecular weight components(ILC)를 분리하고 철분과 복합체를 형성시킨 다음, 철분 결핍된 쥐의 소장에서 loop을 형성시켜 ILC-철분 복합체를 injection하여 철분 흡수도를 조사하였다. Ferrous lactate 100ppm에서 약 25.6%흡수되었고 ferric citrate 100ppm은 24.7%, ferrous sulfate는 19.7%흡수되었다. ILC를 첨가하지 않은 100ppm 철분염 용액은 ferrous sulfate를 제외하고는 흡수도가 감소되었다. 철분 결핍된 쥐에게 gavage 방법에 의하여 철분강화우유를 투여하였을 때 철분 25ppm 시료에서는 ferrous sulfate가 12.5%로 가장 높았고 ferrous lactate는 8.1%, ferric citrate는 6.5% 흡수되었다. 철분 100ppm수준에서는 흡수율이 낮아져 ferrous sulfate는 25ppm 시료보다 절반이하 수준이었다. Ferric citrate는 차이가 거의 없었으며 ferrous lactate는 70%수준이었다. 이상의 결과에서 철분강화우유에 사용하기 적합한 철분염은 ferrous lactate, ferric citrate였는데 특히 ferrous lactate는 제품의 이화학적 품질, 생이용성 측면 모두에서 가장 좋은 것으로 나타났다.

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Influence of lateral motion of cable stays on cable-stayed bridges

  • Wang, P.H.;Liu, M.Y.;Huang, Y.T.;Lin, L.C.
    • Structural Engineering and Mechanics
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    • v.34 no.6
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    • pp.719-738
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    • 2010
  • The aim of this paper concerns with the nonlinear analysis of cable-stayed bridges including the vibration effect of cable stays. Two models for the cable stay system are built up in the study. One is the OECS (one element cable system) model in which one single element per cable stay is used and the other is MECS (multi-elements cable system) model, where multi-elements per cable stay are used. A finite element computation procedure has been set up for the nonlinear analysis of such kind of structures. For shape finding of the cable-stayed bridge with MECS model, an efficient computation procedure is presented by using the two-loop iteration method (equilibrium iteration and shape iteration) with help of the catenary function method to discretize each single cable stay. After the convergent initial shape of the bridge is found, further analysis can then be performed. The structural behaviors of cable-stayed bridges influenced by the cable lateral motion will be examined here detailedly, such as the static deflection, the natural frequencies and modes, and the dynamic responses induced by seismic loading. The results show that the MECS model offers the real shape of cable stays in the initial shape, and all the natural frequencies and modes of the bridge including global modes and local modes. The global mode of the bridge consists of coupled girder, tower and cable stays motion and is a coupled mode, while the local mode exhibits only the motion of cable stays and is uncoupled with girder and tower. The OECS model can only offers global mode of tower and girder without any motion of cable stays, because each cable stay is represented by a single straight cable (or truss) element. In the nonlinear seismic analysis, only the MECS model can offer the lateral displacement response of cable stays and the axial force variation in cable stays. The responses of towers and girders of the bridge determined by both OECS- and MECS-models have no great difference.

An Analytic Study On the Mutual Relation between Method(1) and (2) of ZIEGLER-NICHOLS Control Parameter Tuning (지글러-니콜스 제어파라미터 조정법(1),(2)의 상호 연관성에 대한 해석적 연구)

  • 강인철;최순만;최재성
    • Proceedings of the Korean Society of Marine Engineers Conference
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    • 2001.11a
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    • pp.112-119
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    • 2001
  • Parameter tuning methods by Ziegler-Nickels for control systems are generally classified into Z-N(1) and Z-N(2). The purpose of this paper is to describe what relations exist between methods of Z-N(1) and Z-N(2), or how Z-N(1) method can be originated from Z-N(2) method by analyzing one loop control system of P or PI controller and time delay process. The formulas of Z-N(1) consist of process parameters, L(time delay), $K_m$(gain) and $T_m$(time constant), but Z-N(2) method is based only on the ultimate gain $K_u$ and the ultimate period $T_u$ acquired normally by practical trial without any parameters of Z-N(1). In this paper, for the first step to seek mutual relations, the simple formulas of Z-N(2) are transformed into the formulas composed of the same parameters as Z-N(1) which is derived from the analysis of frequency characteristics. Then, the approximation of the actual ultimate frequency is proposed as important premise in the translation between Z-N(1) and (2). Such equalization and approximation brings a simple approximated formula which can explain how Z-N(1) is originated from the Z-N(2) in the form of formula. And a model system is adopted to compare the approximated formula to Z-N(1) and Z-N(2) methods, the results of which show the effectiveness of the proposals.

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Stomal Complications in Children (소아 장루의 합병증)

  • Park, Joong-Jai;Lee, Joo-Hong;Jung, Jong-Do;Choi, Young-Cheol;Chung, Woo-Shik;Jun, Si-Youl
    • Advances in pediatric surgery
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    • v.8 no.1
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    • pp.11-15
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    • 2002
  • This is a 20 year analysis of the problems associated with enterostomy formation, and closure. Forty-three stomas were established in 43 patients: 23 for anorectal malformations, 11 for Hirschsprung's diseases, 4 for necrotizing enterocolitis, 3 for multiple ileal atresias, 1 for volvulus neonatorum with perforation, and 1 for diaphragmatic hernia with colon perforation. Thirty boys and 13 girls were included (mean age 4.8 months). Stoma complications were encountered in 13 patients (30.2 %): stomal prolapse, stenosis, obstruction, paracolic hernia, retraction, dysfunction, and skin excoriation, Four patients (9.3 %) required stomal revision. Occurrence of complications was not related to age and primary disease, but sigmoid colostomy showed lower complication rate than transverse colostomy (20.0 % vs 42.9 %, p<0.05). There were five deaths but, only one (2.3 %) was directly related to the enterostomy complication. Twenty-one stomas were closed in our hospital and complications occurred in seven patients (33.3 %). The most common complication was wound sepsis in 5 children. In conclusion, because the significant morbidity of stomal formation still exists, refinements of the surgical technique seem to be required, Sigmoid loop colostomy is preferred whenever possible.

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Efficiency Optimization Control of IPMSM Drive using Multi AFLC (다중 AFLC를 이용한 IPMSM 드라이브의 효율 최적화 제어)

  • Choi, Jung-Sik;Ko, Jae-Sub;Chung, Dong-Hwa
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.59 no.3
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    • pp.279-287
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    • 2010
  • Interior permanent magnet synchronous motor(IPMSM) adjustable speed drives offer significant advantages over induction motor drives in a wide variety of industrial applications such as high power density, high efficiency, improved dynamic performance and reliability. This paper proposes efficiency optimization control of IPMSM drive using adaptive fuzzy learning controller(AFLC). In order to optimize the efficiency the loss minimization algorithm is developed based on motor model and operating condition. The d-axis armature current is utilized to minimize the losses of the IPMSM in a closed loop vector control environment. The design of the current based on adaptive fuzzy control using model reference and the estimation of the speed based on neural network using ANN controller. The controllable electrical loss which consists of the copper loss and the iron loss can be minimized by the optimal control of the armature current. The minimization of loss is possible to realize efficiency optimization control for the proposed IPMSM. The optimal current can be decided according to the operating speed and the load conditions. This paper considers the design and implementation of novel technique of high performance speed control for IPMSM using AFLC. Also, this paper proposes speed control of IPMSM using AFLC1, current control of AFLC2 and AFLC3, and estimation of speed using ANN controller. The proposed control algorithm is applied to IPMSM drive system controlled AFLC, the operating characteristics controlled by efficiency optimization control are examined in detail.

A Simulation Method of PID Tuning with Process Modeling in Operating Nuclear Power Plants (가동원전에서 공정모델링을 통한 PID 튜닝 시뮬레이션 방법)

  • Min, Moon-Gi;Jung, Chang-Gyu;Lee, Kwang-Hyun;Lee, Jae-Ki;Kim, Hee-Je
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.63 no.4
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    • pp.290-294
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    • 2014
  • PID(Proportional, Integral, Derivative) controller is the most popular process controllers in nuclear power plants. The optimized parameter setting of the process controller contributes to the stable operation and the efficiency of the operating nuclear power plants. PID parameter setting is tuned when new process control systems are installed or current process control systems are changed. When the nuclear plant is shut down, a lot of PID tuning methods such as the Trial and Error method, Ultimate Oscillation method operation, Ziegler-Nichols method, frequency method are used to tune the PID values. But inadequate PID parameter setting can be the cause of the unstable process of the operating nuclear power plant. Therefore the results of PID parameter setting should be simulated, optimized and finally verified. This paper introduces the simulation method of PID tuning to optimize the PID parameter setting and confirms them of the actual PID controller in the operating nuclear power plants. The simulation method provides the accurate process modeling and optimized PID parameter setting of the multi-loop control process in particular.

Temperature-responsive bioactive hydrogels based on a multifunctional recombinant elastin-like polymer

  • Santo, Vitor E.;Prieto, Susana;Testera, Ana M.;Arias, Francisco J.;Alonso, Matilde;Mano, Joao F.;Rodriguez-Cabello, Jose Carlos
    • Biomaterials and Biomechanics in Bioengineering
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    • v.2 no.1
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    • pp.47-59
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    • 2015
  • A bioactive and multifunctional elastin-like polymer (ELP) was produced by genetic engineering techniques to develop new artificial matrices with the ability to mimic the extracellular matrix (ECM). The basic composition of this ELP is a thermo- and pH-sensitive elastin pentapeptide which has been enriched with RGD-containing domains, the RGD loop of fibronectin, for recognition by integrin receptors on their sequence to promote efficient cell attachment. Hydrogels of this RGD-containing polymer were obtained by crosslinking with hexamethylene diisocyanate, a lysine-targeted crosslinker. These materials retain the "smart" nature and temperature-responsive character, and the desired mechanical behavior of the elastin-like polymer family. The influence of the degree of crosslinking on the morphology and properties of the matrices were tested by calorimetric techniques and scanning electron microscopy (SEM). Their mechanical behavior was studied by dynamical mechanical analysis (DMA). These results show the potential of these materials in biomedical applications, especially in the development of smart systems for tissue engineering.

The Design Status of the Irradiation Facility for Fuel Test (핵연료 시험용 노내조사시험설비의 설계 현황)

  • Park, Kook-Nam;Sim, Bong-Shick;Ahn, Sung-Ho;Yoo, Seong-Yeon
    • Proceedings of the SAREK Conference
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    • 2007.11a
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    • pp.310-315
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    • 2007
  • The FTL has been developed to be able to irradiate test fuels at the irradiation hole(IR1 hole) by considering its utility and user's irradiation requirements. FTL consists of In-Pile Test Section (IPS) and Out-of-Pile System (OPS). Test condition in IPS such as pressure, temperature and the water quality, can be controlled by OPS. For safety assurance IPS is designed to have dual stainless steel pressure vessel and OPS is composed of main cooling water system, emergency cooling water system, LMP(letdown, make-up, purification) system, etc. FTL Conceptual design was set up in 2001, basic design had completed including a design requirement, basic piping & instrument diagram (P&ID), and the detail design in 2004. In 2005, the development team carried out purchase and manufacture hardware and make a contract for construction work. FTL construction work began on August, 2006 and ended on March, 2007. After FTL development which is expected to be finished by 2008, FTL will be used for the irradiation test of the new PWR-type fuel and can maximize the usage of HANARO.

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A Self-Powered RFID Sensor Tag for Long-Term Temperature Monitoring in Substation

  • Chen, Zhongbin;Deng, Fangming;He, Yigang;Liang, Zhen;Fu, Zhihui;Zhang, Chaolong
    • Journal of Electrical Engineering and Technology
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    • v.13 no.1
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    • pp.501-512
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    • 2018
  • Radio frequency identification (RFID) sensor tag provides several advantages including battery-less operation and low cost, which are suitable for long-term monitoring. This paper presents a self-powered RFID temperature sensor tag for online temperature monitoring in substation. The proposed sensor tag is used to measure and process the temperature of high voltage equipments in substation, and then wireless deliver the data. The proposed temperature sensor employs a novel phased-locked loop (PLL)-based architecture and can convert the temperature sensor in frequency domain without a reference clock, which can significantly improve the temperature accuracy. A two-stage rectifier adopts a series of auxiliary floating rectifier to boost its gate voltage for higher power conversion efficiency. The sensor tag chip was fabricated in TSMC $0.18{\mu}m$ 1P6M CMOS process. The measurement results show that the proposed temperature sensor tag achieve a resolution of $0.15^{\circ}C$/LSB and a temperature error of $-0.6/0.7^{\circ}C$ within the range from $-30^{\circ}C$ to $70^{\circ}C$. The proposed sensor tag achieves maximum communication distance of 11.8 m.