• Journal of Korean Society on Water Environment
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• v.29 no.4
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• pp.523-530
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• 2013

This study has been carried out to clarify the characteristics of discharge and pollutant loading according to flow conditions at jiseok stream watershed (JSW). A flow rate and pollutant load in the study watershed were estimated by equation of stage-discharge and discharge-loads rating curve. By using the methods above, I've evaluated the water quality (WQ) of the JSW if it is satisfied with the standard target. I've collected the data of BOD and T-P from the JSW every 8 days for the duration of 12 months. And then, I've schematized the data upon the load duration curve and the results showed me that the WQ of JSW was satisfied with the standard target. I've also collected the same data every each day for the duration of 12 months from JSW and have schematized the data again. And the results showed that it also was satisfied with the standard target. To be concluded, I've determined that point pollution sources of JSW gives more significant impacts to the WQ than non-point pollution sources of JSW and hence, as time goes, point pollution sources will keep depriciating the WQ of JSW. Therefore, further efforts will be required to JSW to maintain the WQ.

• Journal of the Korean Geotechnical Society
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• v.27 no.12
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• pp.97-106
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• 2011

To analyze the lateral load-deflection behavior of steel-concrete composite drilled shafts, a series of lateral pile load tests were performed. The test results were compared with the results from various analytical methods for lateral pile behaviors using the coefficients of subgrade reaction ($k_h$) estimated by pressuremeter test (PMT) and standard penetration test (SPT). As a result, it was found that the analytical methods using the $k_h$ estimated by SPT N value were not suitable for evaluating the pile head lateral load-deflections of the piles within the allowable deflection. However, the methods using the $k_h$ calculated from PMT were able to represent the initial lateral behavior at the head of the piles fairly well. Also, the method by the pressuremeter curve, which was applied directly to the p-y curve of the piles, offered a reasonable lateral behavior estimation by applying the correction factor to the pile materials.

• Geotechnical Engineering
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• v.12 no.6
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• pp.5-20
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• 1996

This paper presents results from a series of model tests on laterally loaded single piles with both free-head and free-tip conditions. Model tests, using a centrifuge apparatus (middie size, Mark II in 7.1.7.) were carried out in sand based on the variation of different gravity acceleration and flexural stiffness of the pile and relative density of the soil. The aims of this study are to estimate the effect of gravity acceleratioil, flexordis stiffness, and relative density on the behavior of the pile embedded in Toyoura sand and to evaluate the applicability of a family of the p-y curves which was presented by several reseachers(Mur chison & O'Neill, neese et n., scott, Det worske veritas, nondner). The Program is deviloped by using p-y curves, and it can be used for the calculation of the displacement distri bution, bending moment distribution, and soil reaction distribution. By comparing meas ured responses with predicted one it is shown that the results of the p-y curve equation presented by Murchison & O'Neill and Kondner agreed with the general trend observed by the centrifuge tests much better than the numerical solutions predicted by the other sets of p -y curves.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.513-517
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• 2015

Background: Growing evidence suggests that the members of the ubiquitin-proteasome system (UPS) are important for tumorigenesis. HERC4, one component, is a recently identified ubiqutin ligase. However, the expression level and function role of HERC4 in lung cancer remain unknown. Our objective was to investigate any correlation between HERC4 and development of lung cancer and its clinical significance. Materials and Methods: To determine HERC4 expression in lung cancer, an immunohistochemistry analysis of a tissue microarray containing samples of 10 lung normal tissues, 15 pulmonary neuroendocrine carcinomas, 45 squamous epithelial cancers and 50 adenocarcinomas was conducted. Receiver operating characteristic (ROC) curve analysis was applied to obtain a cut-off point of 52.5%, above which the expression of HERC4 was regarded as "positive". Results: On the basis of ROC curve analysis, positive expression of HERC4 was detected in 0/10 (0.0%) of lung normal tissues, in 4/15 (26.7%) of pulmonary neuroendocrine carcinomas, in 13/45 (28.9%) of squamous epithelial cancers and in 19/50 (38.0%) of adenocarcinomas. It showed that lung tumors expressed more HERC4 protein than adjacent normal tissues (${\chi}^2$=4.675, p=0.031). Furthermore, HERC4 positive expression had positive correlation with pT status (${\chi}^2$=44.894, p=0.000), pN status (${\chi}^2$=43.628, p=0.000), histological grade (${\chi}^2$=7.083, p=0.029) and clinical stage (${\chi}^2$=72.484, p=0.000), but not age (${\chi}^2$=0.910, p=0.340). Conclusions: Our analysis suggested that HERC4 is likely to be a diagnostic biomarker for lung cancer.

• Asian-Australasian Journal of Animal Sciences
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• v.22 no.4
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• pp.492-499
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• 2009

A Silkie Bantam embryo fibroblast line (named SBF59 line) was successfully established by using direct explant culture and cryopreservation techniques. Cell morphology, viability, dynamic growth and contamination were tested and the karyotype and levels of isoenzymes of lactic dehydrogenase and malic dehydrogenase were analyzed. Four kinds of fluorescent protein extrogenes, including $pEGFP-N_3$, $pECFP-N_1$, $pEYFP-N_1$ and $pDsRed1-N_1$ were transfected into the cells. The results showed that the cells were healthy and possessed a fibrous structure without a change in morphology. The average viability of the cells was 96% before freezing and 90.5% after thawing. The growth curve appeared as typical "S" shape and the cell growth passed through a detention phase, a logarithmic phase and a platform phase; the estimated population doubling time (PDT) was 38.5 h; assays for the presence of bacteria, fungi, viruses and mycoplasmas were negative; the cell line showed no cross contamination when assessed by isoenzyme analysis; the chromosome number was 2n = 78 on more than 88% of occasions; four kinds of fluorescent protein extro-genes appeared to be expressed effectively with a high transfection efficiency between 18.3% and 42.3%. The cell line met the required quality control standard. It not only preserves the genetic resources of the important Silkie Bantam at the cellular level but also provides valuable materials for genomic, post-genomic, somatic cell cloning research and other applications.

• Journal of Korean Academy of Nursing
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• v.38 no.2
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• pp.321-331
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• 2008

Purpose: To examine the relationship between body fat percentage (BFP) and N-K cell activity (NKCA) in Korean breast and rectal cancer patients just after diagnosis. Methods: With 35 subjects enrolled between November 2002 and May 2003, Bioelectrical Impedance Analysis was used to estimate BFP. FACS Analysis was used to measure N-K cell activity. The relationships between BFP and NKCA were identified by using curve estimation, simple regression, and multiple regression, Results: The mean BFPs of the subjects and all the sub-groups were higher than acceptable BFPs. Both the mean NKCAs of male and female subjects were lower than that of healthy women. NKCA was explained by BFP with a 14.9% variance in the total subjects (p<.05). There were significant negative relationships between BFP and NKCA after controlling age, type of cancer, and stage of cancer while no significant relationship was found after controlling for gender. The relationships between BFP and NKCA in the sub-groups of female, breast cancer, and stage I, and II were significant. The relationships between male, rectal cancer, and the stage III, and VI sub-groups were not identified, but they revealed a mild to moderate steep in curve estimation. Conclusion: Weight reduction could prevent the risk and advancement of breast and rectal cancer in Koreans.

• Journal of the Korean Mathematical Society
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• v.45 no.5
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• pp.1443-1482
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• 2008

In this paper we define a Myller configuration in a Finsler space and use some special configurations to obtain results about Finsler subspaces. Let $F^{n}$ = (M,F) be a Finsler space, with M a real, differentiable manifold of dimension n. Using the pull back bundle $({\pi}^{*}TM,\tilde{\pi},\widetilde{TM})$ of the tangent bundle $(TM,{\pi},M)$ by the mapping $\tilde{\pi}={\pi}/TM$ and the Cartan Finsler connection of a Finsler space, we obtain an orthonormal frame of sections of ${\pi}^{*}TM$ along a regular curve in $\widetilde{TM}$ and a system of invariants, geometrically associated to the Myller configuration. The fundamental equations are written in a very simple form and we prove a fundamental theorem. Important lines in a Finsler subspace are defined like special lines in a Myller configuration, geometrically associated to the subspace: auto parallels, lines of curvature, asymptotes. Torse forming vector fields with respect to the Cartan Finsler connection are characterized by means of the invariants of the Frenet frame of a versor field along a curve, and the new notion of torse forming vector fields in the sense of Myller is introduced. The particular cases of concurrence and parallelism in the sense of Myller are completely studied, for vector fields from the distribution $T^m$ of the Myller configuration and also from the normal distribution $T^p$.

• Electrical & Electronic Materials
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• v.7 no.2
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• pp.107-116
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• 1994

In the manufacturing of VLSI circuits, variations of device characteristics due to the slight differences in process parameters drastically aggravate the performances of fabricated devices. Therefore, it is very important to establish optimal process conditions in order to minimize deviations of device characteristics. In this paper, we used one-dimensional process simulator, SUPREM-II, and two dimensional device simulator, MINIMOS 4.0 in order to extract optimal process parameter which can minimize changes of the device characteristics caused by process parameter variation in the case of short channel nMOSFET and pMOSFET device. From this simulation, we have derived the dependence relations between process parameters and device characteristics. Here, we have suggested a method to extract process parameters from design trend curve(DTC) obtained by these dependence relations. And we have discussed short channel effects and device limitations by scaling down MOSFET dimensions.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.585-588
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• 2005

The dissolution characteristic of metal shows the different tendency according to the applied electrical potential, the kind of electrolyte and pH value, etc. In the micro electrochemical machining (ECM), unfavorable oxide/passive layer formation and overall corrosion of electrodes must be prevented. The anodic polarization curve of nickel has distinct three dissolution regions, i.e. two active regions and the transpassive dissolution region. In this paper, the stable electrode potentials of workpiece and tool were determined in sulfuric acid and hydrochloric acid solution, respectively. In each solution, different machining property was shown and possible electrochemical reactions were discussed. On the basis of this experiment, the methodology to obtain the proper electrode potential was suggested.

• Computers and Concrete
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• v.33 no.3
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• pp.265-273
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• 2024

Predicting fracture properties requires an understanding of structural failure behaviour in relation to specimen type, dimension, and notch length. Facture properties are evaluated using various testing methods, wedge splitting test being one of them. The wedge splitting test was numerically modelled three dimensionally using the finite element method on self compacting concrete specimens with varied specimen and notch depths in the current work. The load - Crack mouth opening displacement curves and the angle of rotation with respect to notch opening till failure are used to assess the fracture properties. Furthermore, based on the simulation results, failure curve was built to forecast the fracture behaviour of self-compacting concrete. The fracture failure curve revealed that the failure was quasi-brittle in character, conforming to non-linear elastic properties for all specimen depth and notch depth combinations.