• Title/Summary/Keyword: P-D-C-A모델

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Effects of Water Temperature and Body Weight on Oxygen Consumption Rate of Black Rockfish, Sebastes schlegeli (조피볼락, Sebastes schlegeli의 산소 소비율에 미치는 수온과 체중의 영향)

  • Oh, Sung-Yong;Noh, Choong Hwan;Myoung, Jung-Goo;Jo, Jae-Yoon
    • Korean Journal of Ichthyology
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    • v.19 no.1
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    • pp.1-7
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    • 2007
  • The effect of water temperature (T) and body weight (W) on the oxygen consumption of the fasted black rockfish, Sebastes schlegeli was investigated to provide empirical data for the culture management and bioenergetic growth model of this species. The mean wet body weights of two fish groups used for the present experiment were $12.9{\pm}2.7g$ ($mean{\pm}SD$) and $351.1{\pm}9.2g$. The oxygen consumption rate (OCR) was measured under three water temperature regimes (15, 20 and $25^{\circ}C$) at an interval of 5 minutes for 24 hours using a continuous flow-through respirometer. In each treatment three replicates were set up and 45 fish in small size groups and 6 fish in large size groups were used. The OCRs increased with increasing water temperature in both size groups (p<0.001). Mean OCRs at 15, 20 and $25^{\circ}C$ were 414.2, 691.5 and $843.8mg\;O_2\;kg^{-1}h^{-1}$ in small size groups, and 182.0, 250.7 and $328.2mg\;O_2\;kg^{-1}h^{-1}$ in large size groups, respectively. The OCRs decreased with increasing body weights in three water temperature groups (p<0.001). The mass effect on metabolic rate can be expressed by the power of 0.69~0.75. The data are best described by the relationship: OCR=89.12+28.79T-1.17W. $Q_{10}$ values ranged 1.90~2.79 between 15 and $20^{\circ}C$, 1.49~1.71 between 20 and $25^{\circ}C$, and 1.80~2.03 over the full temperature range, respectively. The energy loss by metabolic cost increased with increasing water temperature and decreasing body weight (p<0.001). Mean energy loss rates by oxygen consumption at 15, 20 and $25^{\circ}C$ were 282.9, 472.3 and $576.3kJ\;kg^{-1}d^{-1}$ in small size groups and 124.3, 171.3 and $224.1kJ\;kg^{-1}d^{-1}$ in large size groups, respectively.

서초프로젝트A 오피스텔 현장의 SHOP DWG

  • Kim, Hyeon-Ung
    • 월간 기계설비
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    • no.11 s.184
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    • pp.57-71
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    • 2005
  • SHOP DWG의 현주소 어디까지 왔는가? 설계에서 제조에 이르는 전 과정을 컴퓨터로 제어하고 관리하는 기술. 캐드(CAD)와 캠(CAM)은 각각 computer-aided design,computer-aided manufacturing의 약칭으로 컴퓨터보조설계와 컴퓨터보조생산을 뜻한다. CAD는 설계도면을 한 장씩 수작업으로 제도하지 않고 설계 데이터베이스의 정보를 CRT(cathode ray tube)에서 화상을 보고 합성하면서 설계하므로 작업을 최적화 할 수 있다. CAD로 설계된 설계도의 내용은 CAM을 통해 NC(수치제어)공작기계에 정확한 작업동작을 지시하게 되며, 작업관리∙가공∙조립∙검사 등의 제조과정을 컴퓨터로 관리하여 작업속도와 제품의 정밀성을 높이게 된다. 최근에는 건축현장의 2D system이 보편화되어 있지만 건축현장의 핵심이라고 할 수 있는 기계설비의 기계실, 또는 조립화 공법 등에는 3차원 CAD∙CAM시스템이 개발되어 입체형상을 화면에 3차원으로 재현할 수 있고, 대상물의 표면적∙부피∙무게∙강도 등의 물리적 성질도 자동 계산하여 최적상태에서 현장의 시공에 적용할 수 있게 되었다. 1960년대 초 미국에서 자동차 모델∙엔진, 항공기 부품 등 의 설계에 수작업의 한계를 느껴 개발되었으며, 한국에서는 70년대 중반에 도입되어 운용되고 있다. 이에 따라 프로그램 회사들은 다양한 방법 등을 SHOP DWG에 적용하여 판매경쟁이 치열하다. (주)우진아이엔에스는 급속한 산업경제의 변화와 무한경쟁시대에 보다 나은 기술개발 투자에도 노력을 기울여, 2000년 11월 용인공장, 생산라인을 천안으로 이전, 확장 하여 배관 및 닥트의 CAD-CAM SYSTEM, P.F.P공법, 기계실3D, 블럭화배관, 닥트자동화 시스템, 설계, 용접공정을 공장화시켰으며, 신 개발품인 S.C.D(SEMI-CON DUCT)를 신설하여 모든 건축물에 맞는 필수적인 제품을 생산함으로써 선택의 폭을 넓히고, 현장 시공능력 효율을 높이고 있다. 이번 호에서는 (주)우진아이엔에스가 95년 설계팀을 발족하여 제로시스템의 3D공법을 공장 및 현장의 SHOP DWG에 적용해왔고 최근에는“서초 프로젝트A”현장에 SHOP DWG의 최대 결집체인 3D활용의 조립화 공법을 적용하여 초고층 오피스텔현장을 시공한 사례를 게재한다. 우진아이엔에스는 30여년의 기술 축척을 바탕으로 최고의 기술력과 풍부한 경험을 통해 아셈무역센타, 타워팰리스1차, 3차 및 목동트라팰리스, 분당트리폴리스, 수원삼성전자 R4, 등 국내굴지의 초고층빌딩 시공을 근거로 초고층의 기본설계를 이해하고 SHOP DWG을 통해서 기계설비공사의 향후 나아갈 지표를 제시하고 있다.

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Inhibition of Lymphatic Endothelial Growth Factor Receptor in a Murine Model of Oral Squamous Cell Carcinoma (구강 편평상피세포암 마우스 모델에서 림프관내피 성장인자 수용체의 억제)

  • Kye, Jun-Young;Park, Young-Wook
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.1
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    • pp.1-9
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    • 2011
  • Purpose: Tumor associated angiogenesis and/or lymphangiogenesis are known to be linked by VEGFR signaling pathways. These processes are regulated by several growth factors including VEGFR-2, VEGFR-3. E7080 is an orally active inhibitor of multiple tyrosine kinases including VEGFR-2, 3. Therefore, it was proposed that E7080 may inhibit angiogenesis and lymphangiogenesis. The aim of this study was to determine the effect of E7080 in a nude mouse model of OSCC. Methods: KB cells were xenografted into the submucosal tissue of the mouth floor of athymic mice. Seven days after the xenograft, the mice were randomized into 2 groups. E7080 were administered orally to the experimental group once per day. The mice were sacrificed 3 weeks after the treatment. The tumors were examined histopathologically. Immunohistochemical assays with anti- VEGF-C, VEGFR-2, VEGFR-3, phosphorylated VEGFR-2/3 (pVEGFR-2/3), and D2-40 antibodies were then performed. Results: The transplantation of human OSCC tumor cells into the mouth floor resulted in the formation of orthotopic tumors. The experimental (E7080 treatment) group showed a slowly increased tumor volume. Moreover, immunohistochemical staining demonstrated higher levels of VEGF-C, VEGFR-2, VEGFR-3, pVEGFR-2/3 and D2-40 expression in the control group than in the experimental group. Conclusion: These results suggest that E7080 may provide therapeutic benefits in OSCC.

Simplified Collapse Analysis of Ship Transverse Structures (선체 횡구조물의 단순화된 최종 강도 해석)

  • P.D.C.,Yang
    • Bulletin of the Society of Naval Architects of Korea
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    • v.26 no.4
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    • pp.57-66
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    • 1989
  • In this paper, a theory for the static analysis of large plastic deformations of 3-dimensional frames, aiming at application to the collapse analysis of ship structures, is presented. In the frame analysis formulation, effects of shear deformations are included. A plastic hinge is inserted into the field of a beam end, and post. failure deformation of the plastic hinge is characterized by finite rotations and extensions. In order to model deep web frames of ship's structures into a framed structures, collapse of thin-walled plate girders is investigated. The proposed analysis method is applied to several ship structural models in the references.

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Study on Optimal Design of Wind Turbine Blade Airfoil and Its Application (풍력발전기 블레이드의 에어포일 최적 설계 및 그 적용 연구)

  • Sun, Min-Young;Kim, Dong-Yong;Lim, Jae-Kyoo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.5
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    • pp.465-475
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    • 2012
  • This study was carried out with two goals. One was the development of a model of a wind turbine blade airfoil and the other was the application of this folding blade. In general, in large-sized (MW) wind turbines, damage is prevented because of the use of a pitch control system. On the other hand, pitch control is not performed in small wind turbines since equipment costs and maintenance costs are high, and therefore, the blade will cause serious damage. The wind turbine proposed in this study does not require maintenance, and the blades do not break during high winds because they are folded in accordance with changes in the wind speed. But generators are not cut-out, while maintaining a constant angle will continue to produce. The focus of this study, the wind turbine is continued by folding blade system in strong winds and gusts without stopping production.

Analysis of Heat Environment in Nursery Pig Behavior (자돈의 행동에 미치는 열환경 분석)

  • Sang, J.I.;Choi, H.L.;Jeon, J.H.;Jeon, B.S.;Kang, H.S.;Lee, E.S.;Park, K.H.
    • Journal of Animal Environmental Science
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    • v.15 no.2
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    • pp.131-138
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    • 2009
  • This study was conducted to find ways to control environment with the difference between body temperature and background temperature based on swine activity, and to apply to the environment control system of swine barns based on the findings. Following are the results. 1. Swine activity related to background temperature was achieved as color images and swine activity status was categorized into cold, comfortable, and hot periods with visualization system (thermal image system). 2. Thermal image system consisted of an infrared CCD camera, an image processing board - DIF (TH3100), an main computer (400Hz, 128M, 586 Pentium model) with C++ program installed. 3. Thermal image system categorizing temperatures into cold, comfortable, and hot was applicable to the environment control system of swine barns 4. Feed intake was higher in cold temperature, and finishing weight and weight gain per day in cold temperature were lower than others (p<0.05).

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Pomegranate Extract Improves Menopausal Syndrome in Ovariectomized Rats (난소 적출 동물모델에서 고흥산 석류 농축액의 갱년기 증상 개선 효과)

  • Wee, Ji-Hyang;Jung, Hyun Jung;Jung, Kyung Ok;Sung, Hea Mi;Shin, Yu-Rim;Park, Ju-Hyun;Seo, Hyeon-Young;Lim, Jung-Min;Chae, Han-Jeong;Lee, Ki Yung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.4
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    • pp.506-515
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    • 2015
  • In this study, the effect of Goheung pomegranate extract on postmenopausal syndrome was evaluated both in vitro and in vivo in ovariectomized Sprague-Dawly (SD) rats. Sixty female SD rats were divided into six groups: sham, sham operation and distilled water; OVX, ovariectomized and distilled water; PE1, ovariectomized and pomegranate concentrate (0.75 mL/twice/d); PE2, ovariectomized and pomegranate concentrate (1.5 mL/twice/d); PE3, ovariectomized and pomegranate concentrate (2.2 mL/twice/d); and CE, ovariectomized and commercial pomegranate concentrate (2.2 mL/twice/d). Percent bone volume (bone volume/tissue volume) and trabecular thickness (Tb.Th) improved in a dose-independent manner in PE1, 2, and 3. Especially, bone mineral density was significantly improved in PE3 (P<0.05) compared to OVX. Pomegranate extract reduced body weight and visceral fat mass. High density lipoprotein cholesterol (HDL-C) level slightly increased in a dose-independent manner in the experimental group. In addition, HDL-C/total cholesterol level of PE3 significantly increased (P<0.05) compared with OVX. These results show that pomegranate concentrate improved blood lipid levels and bone metabolism in ovariectomized rats. Therefore, Goheung pomegranate concentrates are expected to improve cardiovascular and bone-related diseases in menopausal women.

Discrete Wavelet Transform-based SOC Estimation using an Approximation Component of the DCVS for a Li-Ion Cell (이산 웨이블릿 변환(DWT)를 이용한 저주파 전압 성분 기반 리튬 이온 배터리 SOC 추정 방법)

  • Kim, J.H.;Chun, C.Y.;Cho, B.H.;Kim, W.J.;Park, J.P.
    • Proceedings of the KIPE Conference
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    • 2012.07a
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    • pp.244-245
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    • 2012
  • 본 논문에서는 이산 웨이블릿 변환(DWT;discrete wavelet transform)의 다해상도 분석(MRA;multi-resolution analysis)을 통해 분해된 배터리의 저주파 전압 성분(approximation;$A_n$) 기반 SOC(State-of-charge) 추정방법을 소개한다. 급격한 전압 변화의 특성을 나타내는 고주파 전압 성분(detail;$D_n$)이 제거되고 저주파 전압 성분만이 SOC 추정을 위해 사용된다. 이 경우 기존 확장 칼만필터(EKF;extended Kalman filter)에서 SOC 추정에러를 개선하기 위해 사용되었던 노이즈 모델의 생략이 가능하여 알고리즘의 복잡성이 개선된다. 개선된 확장 칼만필터 기반 SOC 추정 결과를 통해 제안된 방법을 검증하였다.

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Effect of Dietary Xanthophylls Supplementation on Pigmentation and Antioxidant Properties in the Egg Yolks (Xanthophylls의 급여가 계란 노른자의 착색 및 항산화성에 미치는 영향)

  • Min, B.J.;Lee, K.H.;Lee, S.K.
    • Journal of Animal Science and Technology
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    • v.45 no.5
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    • pp.847-856
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    • 2003
  • This study was carried out to investigate the effects of dietary xanthophylls supplementation on pigmentation and antioxidant properties in the egg yolk. ISA Brown laying hens aged 50 weeks were fed five kinds of xanthophyll combination such as control(neither natural nor artificial xanthophylls in feed), T1(Commercial diet containing natural xanthopylls in grain + Lutein 10ppm + Capsantin 10ppm), T2(T1 + Capsanthin 65ppm), T3(T1 + Canthaxanthin 65ppm), T4(T1 + Capsanthin 10ppm + Canthaxanthin 65ppm), and T5(T1 + Capsanthin 65ppm + Canthaxanthin 10ppm). The pH values of all egg yolks were not significantly different during storage or feeding periods. CIE L$^{*}$(lightness) values of T2 ~ T5 egg yolks were lower than those of control and T1. Conversely, the CIE a$^{*}$(redness) value of T2 ~ T5 egg yolks showed significantly higher(P<0.05). Egg yolk from chicks fed xanthophylls increased CIE b$^{*}$ values. The CIE b$^{*}$(yellowness) values of T2 ~ T5 egg yolks were higher than control and T1 during storage at 37$^{\circ}C$ for 48 hours respectively. In the antioxidation experiment, dietary xanthophylls supplementation affected lipid antioxidation of egg yolk during storage. The TBARS(O.D.) of egg yolks from chicks fed xanthophylls were lower than that of control during incubation at 37$^{\circ}C$ for 10 hours. In conclusion, dietary xanthophylls supplementation influence to color difference and retardation of lipid oxidation in egg yolk.

Molecular Basis of Organospecific Carcinogensis by Chemical Carcinogens-Study with Breast Cancer Specific Carcinogens: DMBA as an Indirect-Acting carcinogen and NMU as a Direct-Acting cancinogen. (화학적 발암원의 조직 특이성 암유발기전 - DMBA와 NMU의 선택적 유암 발생기전을 중심으로 )

  • 박종영;김승원;박상철
    • Environmental Mutagens and Carcinogens
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    • v.9 no.1
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    • pp.1-12
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    • 1989
  • To study the selective organospecific carcinogenesis by the specific chemical carcinogens, the breast cancer induction model by oral administration of 7, 12-dimethylbenzanthracene (DMBA) or by intravenous injection of N-methylni-trosourea (NMU) on female rats was analyzed. In the present experiment, we compared the effexts of ages on the chemical mammary carcinogenesis by studying the metabolic system of the carcinogenic activation, detoxification or DNA damage and repair. The breast tumor incidence was significantly higher in the young rats of 50 days old than in those of one year old rats. As an index of organospecific DNA damage or repair, the in vivo covalent binding index(CBI) of the specific organs by the specific chemical carcinogens was monitored. And for the analysis of carcinogenic activation, the quantity of cytochrome P450`s was determined with the respective type-specific monoclonal antibody, while the detoxication capacity was deduced by the activity monitoring of glutathione S-transferase (GST) and peroxidase. The skin tissues of the mammary region had the highest CBI with both of DMBA and NMU at 50 days of age. And there were contrasting differences in the contents of carcinogenic activation and detoxication system: that is, the content of T.C.D.D.-inducible cytochrome P450 was high, while the activities of GST and peroxidase was low in the mammary skin tissues at tumor prevalent age. These results led us to conclude that the molecular organospecific carcinogenesis, as illustrated with mammary carcinoge-nesis by DMBA and NMU, is operated probably through the differential capacity of the target tissues in the high carcinogenic activation, low detoxication and the low DNA repair function.

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