• 제어로봇시스템학회:학술대회논문집
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• 1990.10b
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• pp.1387-1392
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• 1990

In this paper, an iterative learning control algorithm for unknown linear discrete systems is proposed by employing a parameter estimator together with an inverse system model. Regardless of initial error and inherent parameter uncertainty, a good tracking control performance is obtained using the proposed learning control algorithm characterized by recursive operations. A sufficient condition for convergency is provided to show the effectiveness of the proposed algorithm. To investigate the performance of the algorithm a series of simulations and experiments were performed for the tracking control of a servo motor.

• 제어로봇시스템학회:학술대회논문집
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• 1991.10b
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• pp.1557-1563
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• 1991

Vendors and consultants struggle to draw attention to their proven experience in discrete CIM in order to convince process manufacturers to adopt CIM technology. The analogy works very well at the periphery where an invoice is an invoice, but disintegrates at the core where modeling of the manufacturing "process" is required. Until recently, it has not been possible to completely and rigorously model entire process plants in real-time, and this missing core element has been called the "CIM GAP" With the recent introduction of the concurrent resolution $^{sm}$ kernel, the CIM GAP now is being closed in the process industries.ntroduction of the concurrent resolution $^{sm}$ kernel, the CIM GAP now is being closed in the process industries.

• Journal of Microbiology and Biotechnology
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• v.22 no.1
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• pp.13-24
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• 2012

The genetic diversity of plant growth-promoting rhizobacterial (PGPR) fluorescent pseudomonads associated with the sugarcane (Saccharum officinarum L.) rhizosphere was analyzed. Selected isolates were screened for plant growthpromoting properties including production of indole acetic acid, phosphate solubilization, denitrification ability, and production of antifungal metabolites. Furthermore, 16S rDNA sequence analysis was performed to identify and differentiate these isolates. Based on 16S rDNA sequence similarity, the isolates were designated as Pseudomonas plecoglossicida, P. fluorescens, P. libaniensis, and P. aeruginosa. Differentiation of isolates belonging to the same group was achieved through different genomic DNA fingerprinting techniques, including randomly amplified polymorphic DNA (RAPD), amplified ribosomal DNA restriction analysis (ARDRA), repetitive extragenic palindromic (REP), enterobacterial repetitive intergenic consensus (ERIC), and bacterial repetitive BOX elements (BOX) analyses. The genetic diversity observed among the isolates and rep-PCR-generated fingerprinting patterns revealed that PGPR fluorescent pseudomonads are associated with the rhizosphere of sugarcane and that P. plecoglossicida is a dominant species. The knowledge obtained herein regarding the genetic and functional diversity of fluorescent pseudomonads associated with the sugarcane rhizosphere is useful for understanding their ecological role and potential utilization in sustainable agriculture.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.353-365
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• 2019

The purpose of this research is to guide the development of the program for the Directive Individual Sand Box Play for the improvement of the self-esteem of children of the dissolved multicultural families. For quantitative analysis data, the scores from before and after the program were compared. The SPSS 18.0 Package was used for statistical analysis. For the qualitative analysis, the linguistic changes in B children during the session were collected and analyzed using the self-expression scale. The research period lasted for around 3 months from February 2017 to May 2017, for a total of 12 sessions which included individual activities, 1 session of group activities, and 1 night and 2 days of family camp activities featuring a total of 6 children. The main results of this research include quantitatively through the program of the Directive Individual Sand Box Play in relation to the social self-esteem capability at z=-2,200 on the level of p<.05, the significant difference was shown. Qualitatively, positive expression increased as sessions proceeded and negative expression reduced regarding the linguistic expressions by session of children B. This means that the method of the Directive Individual Sand Box which presents the topic and in addition, the process of visiting the house of a child which is the most secure environment had shown the effectiveness that increases the improvement of the self-esteem of the children of the dissolved multi-cultural families. According to the diverse special characteristics of clients, a preliminary basic framework for the mobile individual sand box program through the directive approach method will be prepared.

• Food Science of Animal Resources
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• v.43 no.2
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• pp.359-373
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• 2023

This study examined the α-glucosidase inhibitory, and apoptosis- and anti-muscular-related factors of goat meat extracts from forelegs, hind legs, loin, and ribs. The goat meat extracts were evaluated for their α-glucosidase inhibitory activity. The gene and protein expression levels of Bcl-2-associated X (bax), p53, and p21 were examined by reverse transcription polymerase chain reaction (RT-PCR) and immunoblotting in AGS and HT-29 cells. The expression levels of Atrogin-1 and MHC1b were examined by RT-PCR in C2C12 myoblasts, and the expression levels of Atrogin-1, muscle atrophy F-box (MAFbx), muscle RING-finger protein-1 (MuRF-1), and myosin heavy chain-7 were investigated by immunoblotting. α-Glucosidase inhibitory activity was higher in ethanol extract than in hydrous and hot water extracts. BAX and p53 expression levels were higher (p<0.05) in AGS cells treated with goat meat extract than those of cells treated with no goat meat extract. In HT-29 cells, the protein expression levels of BAX, p53, and p21 were higher (p<0.05) in the cells treated with goat meat extract than those of cells not treated with goat meat extract. In dexamethasone-treated C2C12 cells, goat meat extract treatment lower (p<0.05) the expression of Atrogin-1 and lower (p<0.05) the expression of MAFbx and MuRF-1. The results of the present study indicate that goat meat extracts have α-glucosidase inhibitory activity in vitro. In addition, apoptosis was induced in AGS cells and HT-29 cells treated with goat meat extract, and anti-muscular atrophy activity was also observed in C2C12 cells treated with goat meat extract.

• Preventive Nutrition and Food Science
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• v.1 no.2
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• pp.262-268
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• 1996

In Korea, the health authorities and food industry emphasize the need of sanitary food production, which in mainly resulted from the recent growing of consumer's interest in the safety of food. For the reason, development of a new alternative technology to chemicals, currently used for decontamination and disinfestation, has become and urgent task in the domestic and worldwide food industry. Furthermore, the improvement of quality and manufacturing process of processed food is a requisite for winning the competition in export fields. Irradiation technology being practically applicable in the food industry has been well established on the basis of more than 40 years of R&D work in the fields of the increasing availability of food-stuffs, sanitary food production and quarantine treatment in the food trade. The wholesomeness of irradiation foods has been officially approved in 38 countries, of which 30 countries are commercially utilizing food irradiation technology. The first commercial irradiator in Korea(18.5PBq:500k{TEX}$Ci^{60}${/TEX} Co, max. cap; 4MCi) was established at Yeoju-gur, Kyung Ki-do with the technical assistance of Korea Atomic Energy Research Institute in June 1987. As of 1996, thirteen irradiated food groups (over 25 items)have been domestically approved for human consumption and an industrial irradiation facility is also available. However, the domestically approved for human consumption and an industrial irradiation facility is also available. However, the promotion of consumer acceptance to toward ir-radiated foods is considered as a confronted subject to be studied for a commercial utilization.

• Biotechnology and Bioprocess Engineering:BBE
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• v.10 no.3
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• pp.218-224
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• 2005

Surface modification of glutaraldehyde fixed bovine pericardium (GFBP) was success­fully carried out with hyaluronic acid (HA) derivatives. At first, HA was chemically modified with adipic dihydrazide (ADH) to introduce hydrazide functional group into the carboxyl group of HA backbone. Then, GFBP was surface modified by grafting HA-ADH to the free aldehyde groups on the tissue and the subsequent HA-ADH hydrogel coating. HA-ADH hydrogels could be prepared through selective crosslinking at low pH between hydrazide groups of HA-ADH and crosslinkers containing succinimmidyl moieties with minimized protein denaturation. When HA­ADH hydrogels were prepared at low pH of 4.8 in the presence of erythropoietin (EPO) as a model protein, EPO release was continued up to $85\%$ of total amount of loaded EPO for 4 days. To the contrary, only $30\%$ of EPO was released from HA-ADH hydrogels prepared at pH=7.4, which might be due to the denaturation of EPO during the crosslinking reaction. Because the carboxyl groups on the glucuronic acid residues are recognition sites for HA degradation by hyaluronidase, the HA-ADH hydrogels degraded more slowly than HA hydrogels prepared by the crosslinking reaction of divinyl sulfone with hydroxyl groups of HA. Following a two-week subcutaneous implantation in osteopontin-null mice, clinically significant levels of calcification were observed for the positive controls without any surface modification. However, the calcification of surface modified GFBP with HA-ADH and HA-ADH hydrogels was drastically reduced by more than $85\%$ of the positive controls. The anti-calcification effect of HA surface modification was also confirmed by microscopic analysis of explanted tissue after staining with Alizarin Red S for calcium, which followed the trend as observed with calcium quantification.

• Journal of the Korean Society of Tobacco Science
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• v.13 no.1
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• pp.69-73
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• 1991

Varietal response to cool temperature(18$^{\circ}C$) and short (8hr.)-day treatment were investigated under controlled conditions of Phytotron in the Suwon Agronomy Experiment Station. Five flue-cured and one burley tobacco varieties (Nicotiana tabacum L.) were used, and the length of treatment ranging from 8 to 32 days at 3-day intervals and also includes continuous treatment up to the plants were flowered. The days to flower decreased significantly than the no treatment when the length of treatment was 11 to 14 days for the varieties NC82, Br.21 and NC22NF, and 17 to 26 days for SPG-28, Mc.944 and TC499, respectively. And also the number of leaves decreased significantly than the no treatment when the length of treatment was 8 days for NC22NF, 11days for NC82 and Br.21, 14 days for Mc.944, and 17 days for SPG-28 and TC499, respectively. The maximum decreasing ratio of the leaf number by the cool temperature and short-day treatment were 47.7 to 58.5% for NC82, Br.21 and NC22NF, and 38.9% for Mc.944, 33.4% for SPG-28 and 29.0% for TC499, respectively.

• Advances in aircraft and spacecraft science
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• v.4 no.5
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• pp.529-541
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• 2017

Landing phase is one of the crucial and most important phases during robotic aerospace explorations. It concerns the impact of the landing module of a spacecraft on a celestial body. Risks and uncertainties of landing are mainly due to the morphology of the surface, the possible presence of rocks and other obstacles or subsidence. The present work quotes results of a computational analysis direct to investigate the stability during the landing phase of a lander on Phobos, a Mars Moon. The present study makes use of available software tools for the simulation analyses and results processing. Due to the nature of the system under consideration (i.e., large displacements and interaction between several systems), multibody simulations were performed to analyze the lander's behavior after the impact with the celestial body. The landing scenario was chosen as a result of a DOE (Design of Experiments) analysis in terms of lander velocity and position, or ground slope. In order to verify the reliability of the present multibody methodology for this particular aerospace issue, two different software tools were employed in order to emphasize two different ways to simulate the crash-box, a particular component of the system used to cushion the impact. The results show the most important frames of the simulations so as to provide a general idea about how lander behaves in its descent and some trends of the main characteristics of the system. In conclusion, the success of the approach is demonstrated by highlighting that the results (crash-box shortening trend and lander's kinetic energy) are comparable between the two tools and that the stability is ensured.

• Journal of Life Science
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• v.19 no.6
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• pp.705-710
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• 2009

Sodium butyrate (NaBt), a naturally occurring short chain fatty acid derived from carbohydrate metabolism in the gut, is known to exhibit strong anti-cancer potentials in various human cancer cells; however, its action mechanism is poorly understood. In the present study, we demonstrated that NaBt up-regulates levels of E-cadherin, a key cell adhesion molecule implicated as a tumor suppressor, in a cell type-specific manner. Although levels of p21, a potential activator for E-cadherin expression, were also up-regulated by treatment with NaBt in several types of cells, it does not seem to be associated with the activation of E-cadherin in the NaBt-treated cells. Instead, the data from promoter analysis suggest that NaBt up-regulates expression of E-cadherin at the transcription level by enhancing its promoter strength via a CCAAT-box. The elevated E-cadherin in the presence of NaBt was primarily localized at the cell-cell contacts, converting Hep3B cells into a more differentiated form.