• YAKHAK HOEJI
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• v.40 no.5
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• pp.582-590
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• 1996

For the research of antifungal active constituents from natural products, 226 plants were extracted with ether and methanol, separately, and screened antifungal activity against Candida albicans and Penicillium avellaneum cells. The results demonstrated that 30 samlpes showed antifungal activity in ether or methanol extracts and 17 samples in ether extracts and 20 samples in methanol extracts against C. albicans. Against P. avellaneum, 19 samlpes showed antifungal activity in ether or methanol extracts and 17 samples in ether extracts and 11 samples in methanol extracts, respectively. The antifungal activity of natural products against C. albicans were showed more sensitive than P. avellaneum, and the polarity of the solvent was not specific in antifungal activity.

• Language and Information
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• v.2 no.2
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• pp.155-183
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• 1998

The purpose of this paper is to explore the syntactic criteria for determining a secondary predicates as a predicate modifier or a conjunction, and to formalize the semantic aspects of the [-ke] structure as a predicate in Korean. Syntactically, the [-ke] structure is considered to be a secondary predicate when the shared arguments appear in both the [-ke] structure and the main verb structure. On the other hand, if they do not appear in both structures, the [-ke] structure is considered to be a connective element. Semantically the [-ke] structure has numerous aspects such as depictives, resultatives, objectivity, and emphasis. The depictives of the secondary predicate can be formalize as $p{\wedge}q$ where p represents a propositional expression of the secondary predicate and q is a propositional expression of the main verb. Resultatives have the logical form $q{\rightarrow}{\Box}p$, because the consequence has to always be true. However, objectivity has the logical form $q{\rightarrow}{\diamondsuit}p$, because the consequence can be either true or false. Emphasis is represented as $q{\rightarrow}p{\uparrow}$ because the secondary predicate represents the polarity of the event.

• BMB Reports
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• v.48 no.6
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• pp.360-366
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• 2015

Colorectal cancer (CRC), the third most common cancer worldwide, also has the highest rate of cancer-related morbidity and mortality. WNT signaling is initiated by binding of WNT to various receptors, including frizzleds (FZDs), and plays a critical role in CRC and other tumor development by regulating proliferation, differentiation, migration, apoptosis, and polarity. Among the members of the FZD family, FZD6 is broadly expressed in various tissues, and its overexpression has been reported in several cancers, suggesting an important role in cancer development. In this study, we investigated the expression of FZD6 in patients with CRC and found it to be increased in tumors, as compared to paired adjacent non-tumor tissues. Additionally, we found that FZD6 expression was negatively regulated by miR199a5p in CRC cells. These results suggest that overexpression of FZD6, mediated by reduced expression of miR-199a-5p, may play an important role in the development of CRC. [BMB Reports 2015; 48(6): 360-366]

• Journal of the Korean Geophysical Society
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• v.3 no.4
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• pp.245-250
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• 2000

By using amplitude ratios (SV/P, SH/P, SV/SH) and P and S wave polarities, we obtained fault plane solutions of the June 26, 1997 Kyong-ju earthquake. The solutions show $150{\pm}4^{\circ}$ in strike, $63{\pm}6^{\circ}$ in dip and $65{\pm}7^{\circ}$ in rake, or $18{\pm}12^{\circ}$ in strike, $26{\pm}3^{\circ}$ in dip and $120{\pm}5^{\circ}$ in rake. This result implies the stress field trending ENE-WSW, which is remarkably consistent with the previous results obtained from the moment tensor inversion, and from the composite fault plane solution for the events occurred around the Yangsan fault area.

• Journal of Korean Society of Environmental Engineers
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• v.35 no.12
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• pp.897-905
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• 2013

In this study, sorption coefficients (${\log}K_{OC}$, n) for the binding of phenanthrene (PHE) to soil humins, insoluble fraction of soil humc substances (HS), were determined and relationship between the sorption coefficients and structural characteristics of the soil humins were investigated. The soil humins used in the present study were isolated from 7 different soils including 5 domestic soils, an IHSS standard and a peat soil, and characterized by elemental analysis and CPMAS $^{13}C$ NMR method. $^{13}C$ NMR spectral features indicate that the soil humins are mainly made up of aliphatic carbons (57.1~72.3% in total carbon) with high alkyl-C moiety, and the alkyl-C contents ($C_{Al-H,C}$, %) was in order of granite soil Hu (26~42%) > volcanic ash soil, HL Hu (23.9%) > Peat Hu (14.0%). The results of correlation study show that a positive relationship ($r^2$ = 0.77, p < 0.05) between organic carbon normalized-sorption coefficients ($K_{OC}$, mL/g) and alkyl-C contents($C_{Al-H,C}$, %), while negative relationship ($r^2$ = (-)0.74, p < 0.05) between Freundlich sorption parameter (n) and H,C-substituted aromatic carbon contents ($C_{Ar-H,C}$, %). The magnitude of $K_{OC}$ values are also negatively well correlated with polarity index (e.g., PI, N + O)/C) ($r^2$ = (-)0.74, p < 0.1). These results suggest that the binding capacity (e.g., $K_{OC}$) for PHE is increased in soil humin molecules having high contents of alkyl-C or lower polarity, and nonlinear sorption for PHE increased as the H,C-substituted aromatic carbon contents ($C_{Ar-H,C}$, %) in the soil humins increased. The PHE sorption characteristics on soil humins are discussed based on the dual reactive mode of sorption model.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.14 no.1
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• pp.22-29
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• 2000

This paper deals with the dielectric characteristics of $SF_6$ gas gap stressed by $\pm$1.2/44[$mutextrm{s}$] non-oscillating impulse and $\pm$0.4[$mutextrm{s}$]/1.14[MHz] oscillating impulse voltages in the presence of a needle-shape metallic particle in gas-insulated switchgear(GIS). Breakdown voltage-time (V-t) and breakdown voltage-gas pressure (V-p) characteristics were investigated and discussed. The experiments were carried out under highly inhomogeneous field geometry with a needle protrusion whose length and radius are 10[mm] and 0.5[mm], respectively. The gas pressure ranges from 0.1 to 0.5[㎫]. As a result, it was found that the electrical breakdown for both the positive and negative polarity develops with steplike pulses in leader mechanism, When subjected to the positive oscillating impulse voltage, the minimum breakdown voltages appeared in all the gas pressure ranges and the V-t curves have a pronounced upturning at short times to breakdown and give a little dependence of the gas pressure. On the other hand, in the case of the negative polarity the dependence of the V-t and V-p characteristics on the wave shape of the applied voltages is known to be appreciable.

• 한국생물공학회:학술대회논문집
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• 2000.04a
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• pp.470-473
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• 2000

Since the biosynthetic production of indigo and indirubin normally reflects a difficult process including the toxicity of indole to microorganisms, only several bacterial strains have been exploited to produce indigo and indirubin from indole or its derivatives. P. savastanoi BCNU 106, which was a gram negative bacterium, was isolated and tolerant to 10% (v/v) toluene. The indole tolerance level of P. savastanoi BCNU 106 was as high as 160 mg/ml when toluene or p-xylene was added to the medium to 20% by volume. P. savastanoi BCNU 106 grown in a two-phase culture system containing indole(100 mg/ml) and P-xylene (0.2 ml/ml) produced P-xylene-soluble pigments, blue indigo and purple indirubin. Of the conditious tried, the production of indigo and indirubin was found only when P. savastanoi BCNU 106 was grown in the two-phase system overlaid with the organic solvents with appropriate polarity. This study may illustrate that the isolated extremophile P. savastanoi could be used in the microbial conversion process of the industrial potentials.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.66 no.3
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• pp.99-104
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• 2017

The three-phase four-wire power distribution system can be used to supply power to single-phase and three-phase loads at the same time. There are linear loads and nonlinear loads as single-phase loads connected to each phase. The nonlinear load generates a harmonic current during the power energy conversion process. In particular, the single-phase nonlinear load has a higher proportion of generation of the third harmonic current than the harmonics of the other orders. In a three-phase four-wire system, the third harmonic current flows through the neutral wire to the power supply side, affecting the power supply side and the line. Furthermore, the magnitude of the current flowing in the neutral line can be higher than the current flowing in the individual phase. If the neutral current is higher than the phase current, the breaker may be blocked. Therefore, it is necessary to reduce the amount of current flowing in the neutral line by harmonics. There is a method of zigzag connecting a single phase transformer by a method of reducing 3 harmonic current. In this study, the method of reducing the magnitude of the three harmonic currents flowing through the zigzag wire by comparing the polarity and the negative polarity characteristics of the single phase transformer was compared through measurement and simulation.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.24 no.8
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• pp.126-132
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• 2010

This paper presents dielectric characteristics of $N_2$ gas under impulse voltages in a quasi-uniform electric field gap. The experiments were carried out at the test gap applied by the 1.2/50[${\mu}s$] lightning impulse voltage, 180/2500[${\mu}s$] switching impulse voltage, 500[ns]/1[MHz] very fast transient overvoltage(VFTO). The gap separation of sphere-to-plane electrodes was 14[mm] and the electric field utilization factor was about 71.2[%]. The gas pressure ranges from 0.2 to 0.6[MPa]. As a result, the electrical breakdowns are occurred by streamer discharge. Breakdown voltages are linearly increased with the gas pressure and the highest breakdown voltage is appeared under the VFTOs having fast rising time. Breakdown voltages under the positive impulse voltages were higher than those under the negative ones, and also the time to breakdown in the positive polarity is longer than that in the negative polarity.

• Journal of Pharmaceutical Investigation
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• v.34 no.6
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• pp.491-497
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• 2004

We investigated some important factors which affect the transdermal flux of ketoprofen, a nonsteroidal anti-inflammatory agent, as a first step to provide some basic knowledge for the development of a iontophoretic transdermal patch system. Factors such as current density, polarity, buffer (HEPES) and electrolyte concentration and pH were studied using hairless mouse skin. The effect of poly(L-lysin), which is known to affect the electro-osmotic flow through skin, on flux was also studied. Passive flux was about $20\;{\mu}g/cm^2hr$ at pH 4.0, but was negligible at pH 7.4 where all ketoprofen molecules dissolved are ionized (ketoprofen pKa=5.94). At pH 4.0, application of anodal current increased the flux further above the passive level, however anodal flux at pH 7.4 was much smaller than passive flux at pH 4.0. The application of cathodal current at pH 4.0 increased the average flux to $30-40\;{\mu}g/cm^2hr$, depending on the current density applied. At pH 7.4, cathodal flux was only about $5\;{\mu}g/cm^2hr$. Decrease in buffer and electrolyte concentration increased this cathodal flux about 10 fold. However decrease in HEPES buffer concentration 100 fold did not affect the flux. Anodal flux of acetaminophen was much larger than cathodal flux, indicating that electroosmotic flow can be playing an important role in the flux. Poly(L-lysin) increased the cathodal flux at pH 7.4. These results provide some important insights into the mechanism of transdermal flux of ketoprofen and the role of electroosmotic flow.