• Title/Summary/Keyword: Overcome Factors

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Arthroscopic Reconstruction of Bony Defect in Shoulder Instability (골 결손을 동반한 견관절 불안정성의 관절경적 재건술)

  • Kim, Yang-Soo;Ok, Ji-Hoon
    • Clinics in Shoulder and Elbow
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    • v.14 no.1
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    • pp.117-124
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    • 2011
  • Purpose: We reviewed arthroscopic reconstruction among the several treatment options for anterior shoulder instability with a bony Bankart lesion. Materials and Methods: Although open Bankart repair has long been considered the optimal surgical management of anterior shoulder instability, advancements in arthroscopic techniques have led to a recent shift to arthroscopic Bankart repair. However, for cases of a glenoid bony defect, several authors have reported various methods to accurately measure the amount of bony defect. Results: The arthroscopic technique of bony Bankart reconstruction continues to evolve and various methods have followed. To overcome the limitations of single fixation of a Bankart lesion, arthroscopic dual fixation (2 point fixation) has recently been tried to anatomically repair and restore the rigid fixation of a bony fragment. The concept of performing the Bristow-Latarjet transfer procedure under arthroscopy has also recently emerged. However, a large series of cases and long term follow up are required to prove the better results. Conclusion: To obtain a successful outcome for patients with anterior instability with a glenoid bony defect, it is imperative that the surgeon be aware of the accurate status of the bony defect and the intraoperative, postoperative factors associated with the proper treatment of this unstable pathology.

Development of Industrial Transgenic Plants Using Antioxidant Enzyme Genes (항산화효소 유전자를 이용한 산업용 형질전환식물체 개발)

  • Lee, Haeng-Soon;Kim, Kee-Yeun;Kwon, Suk-Yoon;Kwak, Sang-Soo
    • Journal of Plant Biotechnology
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    • v.29 no.2
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    • pp.69-77
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    • 2002
  • Oxidative stress derived from reactive oxygen species (ROS) is one of the major damaging factors in plants exposed to environmental stress. In order to develop the platform technology to solve the global food and environmental problems in the 21st century, we focus on the understanding of the antioxidative mechanism in plant cells, the development of oxidative stress-inducible antioxidant genes, and the development of transgenic plants with enhanced tolerance to stress. In this report, we describe our recent results on industrial transgenic plants by the gene manipulation of antioxidant enzymes. Transgenic tobacco plants expressing both superoxide dismutase (SOD) and ascorbate peroxidase (APX) in chloroplasts were developed and were evaluated their protection effects against stresses, suggesting that simultaneous overexpression of both SOD and APX in chloroplasts has synergistic effects to overcome the oxidative stress under unfavorable environments. Transgenic tobacco plants expressing a human dehydroascorbate reductase gene in chloroplasts were showed the protection against the oxidative stress in plants. Transgenic cucumber plants expressing high level of SOD in fruits were successfully generated to use the functional cosmetic purpose as a plant bioreactor. In addition, we developed a strong oxidative stress-inducible peroxidase promoter, SWPA2 from sweetpotato (lpomoea batatas). We anticipate that SWPA2 promoter will be biotechnologically useful for the development of transgenic plants with enhanced tolerance to environmental stress and particularly transgenic cell lines engineered to produce key pharmaceutical proteins.

Simulation and Evaluation of ECT Signals From MRPC Probe in Combo Calibration Standard Tube Using Electromagnetic Numerical Analysis (전자기 수치 해석을 이용한 Combo 표준 보정 시험편의 MRPC Probe 와전류 신호 모사 및 평가)

  • Yoo, Joo-Young;Song, Sung-Jin;Jung, Hee-Jun;Kong, Young-Bae
    • Journal of the Korean Society for Nondestructive Testing
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    • v.26 no.2
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    • pp.90-98
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    • 2006
  • Signals captured from a Combo calibration standard tube paly a crucial role in the evaluation of motorized rotating pancake coil (MRPC) probe signals from steam generator (SG) tubes in nuclear power plants (NPPs). Therefore, the Combo tube signals should be consistent and accurate. However, MRPC probe signals are very easily affected by various factors around the tubes so that they can be distorted in their amplitudes and phase angles which are the values specifically used in the evaluation. To overcome this problem, in this study, we explored possibility of simulation to be used as a practical calibration tool far the evaluation of real field signals. For this purpose, we investigated the characteristics of a MRPC probe and a Combo tube. And then using commercial software (VIC-3D) we simulated a set of calibration signals and compared to the experimental signals. From this comparison, we verified the accuracy of the simulated signals. Finally, we evaluated two defects using the simulated Combo tube signals, and the results were compared with those obtained using the actual field calibration signals.

Development of Radionuclide Inventory Declaration Methods Using Scaling Factors for the Korean NPPs - Scope and Activity Determination Method - (국내 원전 대상의 척도인자를 활용한 핵종재고량 규명 방법의 개발 - 범위 및 방사능 결정 방법-)

  • Hwang, Ki-ha;Lee, Sang-chul;Kang, Sang-hee;Lee, Kun-Jai;Jeong, Chan-woo;Ahn, Sang-myeon;Kim, Tae-wook;Kim, Kyoung-doek;Herr, Young-hoi
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.2 no.1
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    • pp.77-85
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    • 2004
  • Regulations and guidelines for radioactive waste disposal require detailed information about the characteristics of radioactive waste drums prior to transport to the disposal sites. However, estimation of radionuclide concentrations in the drummed radioactive waste is difficult and unreliable. In order to overcome this difficulty, scaling factor (SF) method has been used to assess the activities of radionuclides, which could not be directly analyzed. A radioactive waste assay system has been operated at Korean nuclear power plant (KORI site) since 1996 and consolidated SF concept has played a dominant role in the determination of radionuclide concentrations. However, SFs are somewhat dispersive and limited in KORI site. Therefore establishment of the assay system using more improved SFs is planned and progressed. In this paper, the scope of research is briefly introduced. For the selection of more reliable activity determination method, the accuracy of predicted SF values for each activity determination method is compared. From the comparison of each activity determination method, it is recommended that SF determination method should be changed from the arithmetic mean to the geometrical mean for more reliable estimation of radionuclide activity. Arithmetic mean method and geometric mean method are compared based on the data set in KORI system. And, this change of SF determination method will prevent an inordinate over-estimation of radionuclide inventory in radwaste drum.

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Scenario Planning based on Collective Intelligence Using Wiki (위키를 활용한 집단지성 기반의 시나리오 플래닝)

  • Han, Jongmin;Yim, Hyun;Lee, Jae-Shin
    • Journal of Technology Innovation
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    • v.20 no.2
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    • pp.29-48
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    • 2012
  • As the complexity and uncertainty of social and economic systems increase, the strategic foresight that actively and effectively responds to the environmental changes becomes important. A wide range of future forecasting methods are available for strategic foresight. Selecting one of the methods depends on several factors such as availability of time and financial resources and the objectives of the exercise. Although trend extrapolation analysis has been used for many years, scenario planning is being widely used by government and corporate as a tool for strategic decision making in recent years. Generally, scenario planning is carried out through workshop, in which experts with diverse backgrounds exchange information, views, and insights and integrate the diverse viewpoints. However, only a small number of experts can participate in a workshop and citizen opinion is not easily transformed into the policy for the scenario exercise due to the limitation of budget and short duration of a project. It is also much harder to develop creative ideas in the workshop because of the limited time and space. In this study, a new scenario process combining scenario workshop and wiki is proposed to overcome the limitation of scenario workshop. This combined approach can be more productive than using scenario workshop alone when developing new ideas. In this study, we applied the combined approach to develop scenarios for the strategic foresight of future media and present suggestions for improving the process.

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Frequency Analysis Using Bootstrap Method and SIR Algorithm for Prevention of Natural Disasters (풍수해 대응을 위한 Bootstrap방법과 SIR알고리즘 빈도해석 적용)

  • Kim, Yonsoo;Kim, Taegyun;Kim, Hung Soo;Noh, Huisung;Jang, Daewon
    • Journal of Wetlands Research
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    • v.20 no.2
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    • pp.105-115
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    • 2018
  • The frequency analysis of hydrometeorological data is one of the most important factors in response to natural disaster damage, and design standards for a disaster prevention facilities. In case of frequency analysis of hydrometeorological data, it assumes that observation data have statistical stationarity, and a parametric method considering the parameter of probability distribution is applied. For a parametric method, it is necessary to sufficiently collect reliable data; however, snowfall observations are needed to compensate for insufficient data in Korea, because of reducing the number of days for snowfall observations and mean maximum daily snowfall depth due to climate change. In this study, we conducted the frequency analysis for snowfall using the Bootstrap method and SIR algorithm which are the resampling methods that can overcome the problems of insufficient data. For the 58 meteorological stations distributed evenly in Korea, the probability of snowfall depth was estimated by non-parametric frequency analysis using the maximum daily snowfall depth data. The results of frequency based snowfall depth show that most stations representing the rate of change were found to be consistent in both parametric and non-parametric frequency analysis. According to the results, observed data and Bootstrap method showed a difference of -19.2% to 3.9%, and the Bootstrap method and SIR(Sampling Importance Resampling) algorithm showed a difference of -7.7 to 137.8%. This study shows that the resampling methods can do the frequency analysis of the snowfall depth that has insufficient observed samples, which can be applied to interpretation of other natural disasters such as summer typhoons with seasonal characteristics.

Corrosion Stability of Iron Artifacts after Treating with Water Treatment (수처리제를 사용한 철제유물의 부식 안정성 연구)

  • Jeong, Ji Hae
    • Journal of Conservation Science
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    • v.33 no.5
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    • pp.381-390
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    • 2017
  • Desalination is the main focus of the stabilization of iron artifacts. However, drawbacks such as re-corrosion are noted due to the uncertainty in the elimination of the corrosive factors and artifacts. Several studies have been carried out on the effects of corrosion inhibitors to overcome these shortcomings. In this study, the effects of type 3 water treatment on corrosion inhibitors were investigated. Surfaces of samples that contained film corrosion inhibitors on their surfaces were analyzed. The results revealed that the surface rust was removed from the sample of type 1 No. 2 that was mainly composed of phosphate. The average weight reduction rates of re-corrosion samples were 0.58, 0.03, and 0.07% for type 1 No. 2, type 2 No. 2, and type 3 No. 2 respectively. The changes in the $Cl^-$ ion, a corrosive agent were found to be 28.60, -4.08, and -1.94 ppm for type 1 No. 2, type 2 No. 2, and type 3 No. 2 respectively. The water-treated films were analyzed by X-ray photoelectron spectroscopy (XPS). It was found that type 2 No. 2 had less Fe the basis metal, than that in type 3 No. 2 indicating much better film. Moreover, Si content was higher in type 2 No. 2, based on the silicate content, than in type 3 No. 2. They are speculated to be the reason or the formation of a better film. Type 1 No. 2, which is mainly composed of phosphate, would be inappropriate as a metal artifact conservation treatment. It was determined that type 2 No. 2 and type 3 No. 2 water treatments, which are mainly composed of silicate, provided excellent corrosion inhibiting effects. Corrosion inhibitors could be used as emergency treatment agents during the excavation of iron artifacts.

The Potential Therapeutic Effects of Endothelial Progenitor Cells in Ischemic Cardiovascular Disease (허혈성 심혈관 질환의 치료제로서 혈관내피전구세포(EPC)의 가능성에 대한 고찰)

  • Kim, Da Yeon;Kim, Bo Min;Kim, So Jung;Choi, Jin Hee;Kwon, Sang-Mo
    • Journal of Life Science
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    • v.30 no.7
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    • pp.651-659
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    • 2020
  • Cardiovascular disease is one of the leading causes of death across the world, and gold-standard treatments such as percutaneous coronary intervention and artery bypass grafting have various limitations including myocardial damage and subsequent maladaptive cardiac remodeling. To overcome this, stem-cell therapies are emerging as a promising strategy for cardiovascular regeneration. Endothelial progenitor cells (EPCs) have high potential to proliferate and differentiate into endothelial cells for vascularization and tissue regeneration, and several clinical trials have explored EPC function in tissue repair in relation to clinical safety and improving cardiac function. Consequently, EPC has been suggested as a feasible stem-cell therapy. However, autologous EPC transplantation in cardiovascular disease patients is restricted by risk factors such as age, smoking status, and hypertension that lead to reduced bioactivity in the EPCs. New approaches for improving EPC function and stem-cell efficacy have therefore been suggested, including cell priming, organoid culture systems, and enhancing transplantation efficiency through 3D bioprinting methods. In this review, we provide a comprehensive understanding of EPC characteristics, therapeutic approaches, and the current state of clinical research into EPCs as stem-cell therapy for cardiovascular disease.

Experimental Study on Improvement of Pipe-rack Joint (Pipe-rack접합부 개선방법에 관한 실험적 연구)

  • Lee, Jong-Kun
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.22 no.4
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    • pp.1-9
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    • 2018
  • The development of new technology and process in industrial Plant which builds integrated structures, facilities and systems. Has become a key element for strengthening its competitiveness. Although domestic industrial Plant has demonstrated excellence in technology with a persistent increase in order quantity and orders received, the technology gap between countries has narrowed due to global construction trend. Therefore, it is necessary to develop new technology that could help overcome constraints and limitations of the current one to follow the trend in the age of unlimited competition. This study has focused on assembly technology of Pipe-rack joint connection in an effort to strengthen technological competitiveness in industrial Plant. Through an analysis of earlier studies on Pipe-rack and a coMParative analysis of strengths and weaknesses of current assembly technology of it, a new design plan has been made to improve it efficiently. In doing this, standards for design factors of both structural and performance features have been drawn, and value of stress, strain, moment and rotation has been calculated using finite element analysis. As a result, installation technology of modular type Pipe-rack, which has not been developed in Korea and is differentiated from the current one, has been developed. It is considered that the technology reduces work time and saves cost due to simplified joint connection of steel structure, unlike the current one. Moreover, since it is installed without a welding process in the field, industrial accidents would be reduced, which is likely to have economic competitiveness and satisfy.

The Electrochemical Studies of Non-enzymatic Glucose Sensor on the Nickel Nanoparticle-deposited ITO Electrode (ITO 전극 위에 고정된 니켈 나노 입자를 이용한 무효소 혈당센서에 관한 전기화학적인 연구)

  • Oh, In-Don;Kim, Samantha;Choi, Young-Bong
    • Journal of the Korean Electrochemical Society
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    • v.17 no.3
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    • pp.164-171
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    • 2014
  • A highly sensitive and selective non-enzymatic glucose sensor has gained great attention because of simple signal transformation, low-cost, easily handling, and confirming the blood glucose as the representative technology. Until now, glucose sensor has been developed by the immobilization of glucose oxidase (GOx) on the surface of electrodes. However although GOx is quite stable compared with other enzymes, the enzyme-based biosensors are still impacted by various environment factors such as temperature, pH value, humidity, and toxic chemicals. Non-enzymatic sensor for direct detecting glucose is an attractive alternative device to overcome the above drawbacks of enzymatic sensor. Many efforts have been tried for the development of non-enzymatic sensors using various transition metals (Pt, Au, Cu, Ni, etc.), metal alloys (Pt-Pb, Pt-Au, Ni-Pd, etc.), metal oxides, carbon nanotubes and graphene. In this paper, we show that Ni-based nano-particles (NiNPs) exhibit remarkably catalyzing capability for glucose originating from the redox couple of $Ni(OH)_2/NiOOH$ on the surface of ITO electrode in alkaline medium. But, these non-enzymatic sensors are nonselective toward oxidizable species such as ascorbic acid the physiological fluid. So, the anionic polymer was coated on NiNPs electrode preventing the interferences. The oxidation of glucose was highly catalyzed by NiNPs. The catalytically anodic currents were linearly increased in proportion to the glucose concentration over the 0~6.15 mM range at 650 mV versus Ag/AgCl.