• 제목/요약/키워드: Outcomes Measurement

검색결과 287건 처리시간 0.051초

Leukocytospermia 환자에서의 IVF와 ICSI의 결과 비교 (Comparision of Conventional IVF and ICSI for Leukocytospermia)

  • 권윤정;김지수;강희규;손인표;최규완;이승재;박종민
    • Clinical and Experimental Reproductive Medicine
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    • 제25권3호
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    • pp.245-249
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    • 1998
  • White blood cells (WBCs) are present in most human ejaculates, but abnormally high concentration of seminal leukocytes may reflect an underlying pathological condition. The World Health Organization (WHO) has defined leukocytospermia as status of more than $10^6$ WBC/mL of semen. The purpose of this study was firstly, to compare the outcomes between conventional IVF and ICSI in leukocytospermia, and secondly, to investigate whether ICSI may be an alternative treatment for patients with leukocytospermia. Total 121 cycles of conventional IVF and ICSI candidates underwent IVF cycles at PL Infertility Clinic. Semen Parameters including concentration, motility, morphology of spermatozoa and concentration of leukocytes were assessed from the raw ejaculates. There was no difference in sperm concentration, motility and morphology. The rates of fertilization and good embryo development from ICSI were significantly higher than those from conventional IVF in leukocytospermia (63.9% & 48.6%, respectively for ICSI group and 33.4% & 24.1%, respectively for IVF group, p<0.001). The pregnancy rate after ICSI was also higher than that from conventional IVF (34.3% vs 21.6%, p<0.05). These results indicate that the presence of seminal leukocytes ($>1\times10^6$ WBC/mL of semen) is adversely related with fertilization, embryo development and pregnancy rate. Therefore the measurement of seminal leukocytes in routine semen analysis appears to be of prognostic value with regard to male fertilizing potential. In conclusion, it is suggested that ICSI is an alternative choice of treatment for patients with leukocytospermia.

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Serum biomarkers for predicting pregnancy outcome in women undergoing IVF: human chorionic gonadotropin, progesterone, and inhibin A level at 11 days post-ET

  • Kim, Jee-Hyun;Shin, Mi-Sun;Yi, Gwang;Jee, Byung-Chul;Lee, Jung-Ryeol;Suh, Chang-Suk;Kim, Seok-Hyun
    • Clinical and Experimental Reproductive Medicine
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    • 제39권1호
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    • pp.28-32
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    • 2012
  • Objective: This study was performed to assess the prognostic value of serum hCG, progesterone, and inhibin A levels measured at 11 days post-ET for predicting pregnancy outcome in women participating in IVF. Methods: Between May 2005 and April 2008, sera were obtained from 70 infertile women who underwent IVF-ET at 11 days post-ET and stored. HCG, progesterone, and inhibin A levels were measured by commercial enzyme-linked immunosorbent assay kits. The predictive accuracy of hCG, progesterone, and inhibin A levels for establishment of intrauterine pregnancy and ongoing pregnancy was calculated by receiver-operating characteristic curve analysis. Results: For the prediction of intrauterine and ongoing pregnancy, serum hCG was better than progesterone and inhibin A. The predictive performance of progesterone and inhibin A was similar. The serum progesterone and inhibin A levels were significantly correlated each other (r=0.915, p=0.010). Conclusion: A single measurement of the serum hCG level is sufficient to predict pregnancy outcome in IVF-ET patients.

프로브 자전거 센서자료를 이용한 자전거 주행안전성 및 이동성 통합평가기법 개발 (A Methodology for Evaluating Cycling Safety and Mobility using Probe Bicycle Sensor Data)

  • 주신혜;오철
    • 대한교통학회지
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    • 제30권3호
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    • pp.43-55
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    • 2012
  • 자전거는 비동력 무탄소 교통수단으로써 지속가능한 녹색교통수단으로 각광받고 있으며 자전거이용활성화를 위해서는 빠르고 쾌적하며, 안전한 자전거 주행환경을 제공하여 자전거가 가지고 있는 제약을 극복하여 보다 중요한 교통수단으로서의 기능을 할 수 있도록 해야한다. 따라서 본 연구에서는 자전거 모니터링의 일환으로 주행환경 평가시나리오 및 관성센서 및 자전거 속도계가 장착된 프로브자전거를 활용한 자전거 주행환경 평가기법을 제시하였다. 또한 제시된 평가기법은 신뢰성 분석기법인 FTA(Fault Tree Analysis)이론을 적용하여 자전거 주행안전성(CSI)과 주행이동성(속도)을 동시에 평가할 수 있는 통합평가지표를 제시함으로써 실효성이 높을 것으로 판단된다. 본 연구의 결과는 GPS와 관성센서가 통합된 자전거 전용단말기를 개발하여 공공자전거 시스템의 구성요소로 발전시킨다면 보다 지능적인 자전거 교통 모니터링이 가능할 것으로 기대된다.

Acupuncture for Subacute and Chronic Post-thoracotomy Pain in Patients with Traumatic Multiple Rib Fractures: A Study Protocol for a Randomised-controlled, Two-arm, Parallel Design, Pilot Trial

  • Kim, Kun Hyung;Cho, Hyun Min;Lee, Chan Kyu;Seok, JunePill;Kim, Seon Hee;Kim, Jung-Eun;Shin, Yu Kyung;Kim, Min Kyung
    • Journal of Acupuncture Research
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    • 제35권2호
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    • pp.95-100
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    • 2018
  • Background: The aim of this study is to assess the feasibility of acupuncture treatment for the management of subacute and chronic post-thoracotomy pain in patients with traumatic multiple rib fractures. Methods: A total of 30 participants who have undergone thoracotomy after traumatic multiple rib fractures will be recruited. Participants will be invited and equally randomised into acupuncture plus usual care and usual care alone groups. A computer-generated random number sequence will be used and concealed using opaque, sealed, sequentially numbered envelopes. Twelve sessions of manual and electrical acupuncture performed by Korean medicine doctors will be provided over a span of 3 months to participants allocated to the acupuncture group. Participants in the usual care group will continue pain medication, exercise and physical therapy as required. Study feasibility will be measured based on the proportion of patients who complete the measurement of pain at 12 or 24 weeks after baseline. The clinical outcomes will include; the average pain intensity over the recent week at rest, movement and cough, quality of life, patient's global assessment of recovery, respiratory function measured by the pulmonary function test and use of pain medication at 4, 8, 12 and 24 weeks after enrolment. Adverse events will be recorded for all participants. Written informed consent will be obtained from all participants. The local ethics committee has approved the study. This pilot trial will inform further studies investigating the potential role of acupuncture for subacute and chronic post-thoracotomy pain in patients with traumatic multiple rib fractures.

Acupuncture Treatment of Adhesive Capsulitis of the Shoulder: A Randomized Controlled Pilot Trial

  • Kim, Jung-Eun;Kim, Sung-Phil;Kim, Ae-Ran;Park, Hyo-Ju;Kwon, Ojin;Jung, So-Young;Cho, Jung-Hyo;Kim, Joo-Hee;Choi, Sun-Mi
    • Journal of Acupuncture Research
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    • 제35권3호
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    • pp.120-128
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    • 2018
  • Background: Adhesive capsulitis (AC) is a common condition that includes shoulder pain and limited movement. Despite more than 100 years of AC treatment, the most efficacious treatment remains unclear. The aim of this study was to evaluate the feasibility of a randomized controlled trial (RCT) using acupuncture for AC. Methods: Thirty participants with AC were randomly assigned to acupuncture (A) or sham acupuncture (SA) groups. The participants received 15 acupuncture sessions over 6 weeks, and follow-up occurred for an additional 4 weeks thereafter. The primary clinical outcome was the numeric rating scale (NRS) for shoulder pain 6 weeks from the baseline. Secondary outcomes included range of motion (ROM) in the shoulder, the shoulder pain and disability index (SPADI), the EuroQol-5 dimensions (EQ-5D), the Pittsburgh sleep quality index (PSQI), and the patient global impression of change (PGIC). Results: Thirty participants were enrolled out of 37 screened individuals. Recruitment was conducted between August 2014 until May 2015. A total of 28 participants (93%) completed the 6-week intervention, and 26 participants (87%) completed the study. NRS, ROM, SPADI, EQ-5D, PSQI, and PGIC scores improved in both the experimental group and the sham group after 6 weeks, but the difference between the groups was not statistically significant. Adverse events were reported by 12 participants, although these events were not associated with acupuncture. Conclusion: A future RCT for AC may be feasible with some modifications to the recruitment plan and the secondary outcome measurement methods.

A Comparative Study on Virtual Try-on Systems using Body Measurement Input

  • Lim, Ho-Sun;Istook, Cynthia
    • The International Journal of Costume Culture
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    • 제13권2호
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    • pp.118-129
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    • 2010
  • Digital technology introduced into the clothing and fashion industry is evolving to digital virtual fashions and consumer-centered mass-customized production systems. Today the application of such 3D virtual try-on systems is being expanded gradually in the clothing industry. This study purposed to make virtual avatars and virtual garments using OptiTex and V-stitcher virtual software and compared the appearance of the virtual garments put on the virtual avatars. For this, we created virtual avatars and virtual garments using body measurements obtained from jive subjects of top jive body shapes, respectively, using $[TC]^2$ body scanner. According to the results of comparing the outcomes of the two different virtual software systems, virtual avatar II of V-Stitcher tended to have a more round and lifted hip and the waist line at a higher position. In addition, the body curves and shapes of a virtual avatar affect the appearance of virtual garments. This study applied the same body measurements to virtual avatars and the same pattern to virtual garments, but when different kinds of virtual software were used, the virtual avatars and virtual garments showed different appearance and fit. This result may mean that when customers buy apparel products using different kinds of virtual try-on systems, their evaluation of appearance can vary depending on the virtual try-on system. Therefore, research needs to be made actively for the development and use of linkage programs that can reflect actual body measurements between virtual software systems and 3D body scanning systems.

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연구참여자에 의한 주택실내 휘발성 유기화합물 농도의 측정 (Measurement of Residential Volatile Organic Compound Exposure Through A Participant-Based Method)

  • 황윤형;이기영;김서진;홍윤철;전종관;조수헌
    • 한국환경보건학회지
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    • 제37권5호
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    • pp.369-375
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    • 2011
  • Objectives: Exposure to hazardous chemicals during pregnancy may result incritical reproductive health outcomes. Indoor residential levels are significant component of personal exposure. The collection of residential exposure data has been hampered by the cost and participant burden of health studies of indoor air pollution. This study utilized a participant-based approach to collect volatile organic compounds concentration from homes. Methods: Four hundred thirteen women were recruited from three major hospitals in Seoul and Gyeongi Provence and 411 agreed to participate. A passive sampler (OVM 3500, 3M, USA) with instructions were given to the participants, as well as a questionnaire. They were asked to deploy the sampler in their homes for three to five days and return them viapre-stamped envelope. Results: Three hundred forty six participants returned the sampler. Among the returned samplers, three hundred samplers satisfied our monitoring quality criteria. The success rate of the monitoring method was 73%. The geometric mean of TVOC level was 429(2) ${\mu}g/m^3$. The TVOC guideline of 500 ${\mu}g/m^3$ was exceeded in 38% of the houses. The residential VOC levels were significantly associated with remodeling of the house. Conclusions: The results suggested that a participant-based sampling approach may be a feasible and costeffective alternative to exposure assessment involving home visits by a field technician.

임상가를 위한 특집 4 - CBCT 검사법의 정도관리 및 선량 (Radiation Doses and Quality Assurance in Cone Beam CT(CBCT))

  • 최용석;김규태;황의환
    • 대한치과의사협회지
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    • 제52권3호
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    • pp.153-163
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    • 2014
  • 3-dimensional information for anatomic stucture plays a role as integral part in clinical aspect of dental practice. CBCT(cone beam computed tomography) has been accepted as useful diagnostic tool offering Volume data and images for evaluating teeth and jaws in lower radiation dose than conventional CT. CBCT equipment is essential for the quality assurance of it to ensure continued satisfactory performance and result of adequate images. Dental practitioner and oral and maxillofacial radiologist should have a responsibility and critical thinking to deliver this technology to patients in a responsible way, so that diaganostic value is maximised and radiation doses kept as low as resonably achievable. CBCT imaging modality should be used only after a review of the patient's health and imaging history and the completion of a thorough clinical examination. Clinical guidelines are systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances Dental practitioners should prescribe CBCT imaging only when they expect that the diagnostic yield will benefit patient care, enhance patient safety or improve clinical outcomes significantly. Knowledge of patient dose is essential for clinicians who are making the decision regarding the justification of the exposure. There are some limitation in the measurement of patient dose in CBCT for the approval and adaptation of conventinal methodolgy in CT. It is also important to ensure that doses are optimised and in line with any national and international guidelines. The higher radiation doses of CBCT compared with conventional radiography, mean that high standards must be maintained. The Quality Assurance(QA) programme should entail surveys and checks that are performed according to a regular timetable. QA programme should be maintained by staff to ensure adherence to the programme and to raise its importance among staff.

과학교사에 의해 조성되는 심리적 학습환경이 학생들의 과학 성취도에 미치는 효과 (The Effects of the Psychological Learning Environment by Science Teachers on Students' Science Achievement)

  • 이재천;김범기
    • 한국과학교육학회지
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    • 제19권2호
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    • pp.315-328
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    • 1999
  • 과학 및 과학교과에 대한 학생들의 정의적 인식이 어떻게 하면 긍정적인 방향으로 행동변화를 가져올 수 있는가?에 연구의 목적을 가지고서, 과학수업 과정에서 교사에 의한 학습환경의 분위기나 풍토를 조성하는 심리적 측면이 학생들의 성취도에 미치는 영향을 조사하였다. 1년간 동일한 교사로부터 과학수업을 받은 중 고등학교 2, 3학년학생들이 가지고 있는 교사인식을 바탕으로 심리적 학습환경을 측정하고, 이 환경인식에 따른 과학불안 인식, 과학에 대한 태도, 과학 탐구능력, 과학성취도와의 관계 및 효과를 조사하였다. 이를 토대로 밝혀진 결과는 심리적 학습 환경은 학생들의 정의적 인식 성향과 인지적 학습결과에 직 간접적인 효과를 주며, 유의한 정적 상관을 보였다. 즉, 교사가 조성하는 수업태도, 인성특성, 학습분위기, 수업행동, 지원적 행동 등은 학생들의 과학에 대한 정의적인 행동특성을 변화시킬 수 있는 수업의 사태로써 유의하게 작용할 수 있으며, 과학 성취에도 의미있게 작용한다는 점을 시사해주고 있다.

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Feasibility Study of Patient Specific Quality Assurance Using Transit Dosimetry Based on Measurement with an Electronic Portal Imaging Device

  • Baek, Tae Seong;Chung, Eun Ji;Son, Jaeman;Yoon, Myonggeun
    • 한국의학물리학회지:의학물리
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    • 제28권2호
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    • pp.54-60
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    • 2017
  • This study was designed to measure transit dose with an electronic portal imaging device (EPID) in eight patients treated with intensity modulated radiotherapy (IMRT), and to verify the accuracy of dose delivery to patients. The calculated dose map of the treatment planning system (TPS) was compared with the EPID based dose measured on the same plane with a gamma index method. The plan for each patient was verified prior to treatment with a diode array (MapCHECK) and portal dose image prediction (PDIP). To simulate possible patient positioning errors during treatment, outcomes were evaluated after an anthropomorphic phantom was displaced 5 and 10 mm in various directions. Based on 3%/3 mm criteria, the $mean{\pm}SD$ passing rates of MapCHECK, PDIP (pre-treatment QA) for 47 IMRT were $99.8{\pm}0.1%$, $99.0{\pm}0.7%$, and, respectively. Besides, passing rates using transit dosimetry was $90.0{\pm}1.5%$ for the same condition. Setup errors of 5 and 10 mm reduced the mean passing rates by 1.3% and 3.0% (inferior to superior), 2.2% and 4.3% (superior to inferior), 5.9% and 10.9% (left to right), and 8.9% and 16.3% (right to left), respectively. These findings suggest that the transit dose-based IMRT verification method using EPID, in which the transit dose from patients is compared with the dose map calculated from the TPS, may be useful in verifying various errors including setup and/or patient positioning error, inhomogeneity and target motions.