• Knowledge Management Research
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• v.16 no.4
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• pp.1-16
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• 2015

This paper aims to explore the small and medium sized enterprises'(SMEs') technological innovation through an open innovative strategy. Researchers have identified open innovation as external search 'breadth' and 'depth'. Although an open innovation strategy is well known as an effective way for SMEs' innovation, this stream of research examines differences between pursuing breadth of external knowledge and depth of external knowledge for SEMs' innovation. The sample comprises a total of 1106 SMEs included in the Korean Innovation Survey, and logistic regression analysis and odds ratio comparison were used to evaluate the relationship between external knowledge search and innovation outcomes. The results show that both 'breadth' and 'depth' positively affect the SMEs' innovation. When SMEs are simultaneously pursuing external searching for breadth and depth, however, a negative result on innovation outcome followed because of the lack of their internal resources and capacities. Despite these contributions, we have certain limitations that can be regarded as means of future research. Even though breadth and depth are adopted to measure the way of how a firm sources the external knowledge, companies may place the different weight on each source of knowledge. And also, it is difficult to understand how the knowledge gained through external search contributes to a firm's incremental and radical innovation, respectively.

• Clinical and Experimental Reproductive Medicine
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• v.39 no.4
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• pp.182-186
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• 2012

Objective: Many studies have demonstrated that hydrosalpinx has a detrimental effect on the outcome of IVF. Treating hydrosalpinges prior to the IVF procedure in women with hydrosalpinges is thought to improve the likelihood of successful IVF outcome. Vaginal ultrasound-guided aspiration of hydrosalpinx fluid (HSF) with injection of the sclerosing agent in situ might be simpler than invasive procedures like salpingectomy. Therefore, we carried out a retrospective study on the effects of ultrasound-guided HSF aspiration and injection of the sclerosing agent of ultrasonically diagnosed hydrosalpinx on IVF outcome. Methods: In our retrospective study, 97 tubal factor infertile female patients that underwent IVF treatment between January 2005 and December 2012 at the Reproductive Medicine Center of CHA Hospital were divided into two study groups. Fifty-six patients underwent interventional ultrasound sclerotherapy (group 1), and the remaining 41 patients received laparoscopic salpingectomy (group 2) before IVF. We compared the IVF outcomes of the two groups. Results: The results showed that ultrasound-guided HSF aspiration and sclerotherapy have IVF outcomes comparable to laparoscopic salpingectomy. Conclusion: Interventional ultrasound guided sclerotherapy before IVF is an effective and less invasive prophylactic intervention alternative to salpingectomy with hydrosalpinx.

• Asian Oncology Nursing
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• v.12 no.3
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• pp.195-203
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• 2012

Purpose: To summarize and review the methodological quality of the evidence from trials examining the effectiveness of physical exercise in patients undergoing allogeneic hematopoietic stem cell transplantation (Allo-HSCT). Methods: Six randomized clinical trials (RCTs) were identified, reviewed for substantive results, and assessed for methodological quality. Results: Six trials met all methodological criteria on the modified Jadad score above 3 out of 5 points. Failure to blind the outcome assessor, and failure to describe the method of blinding of outcome assessor appropriately were the most prevalent methodological shortcomings. Various exercise modalities have been applied, differing in content, frequency, intensity, and duration. Positive results have been observed in part for a diverse set of outcomes, including physical and psychological performance. Conclusion: The trials reviewed in this study were of moderate methodological quality. They suggest that exercise in patients undergoing Allo-HSCT may be safe and feasible, and in part patients benefit from increased physical performance both during and after transplantation. Future RCTs should use larger samples, appropriate comparison groups, and a standard of outcome measures, and examine what kind of exercise intervention (aerobic vs. resistance vs. combined) is the most effective for Allo-HSCT patients. It would be necessary to define contraindication for exercise to guarantee its safety.

• Research in Community and Public Health Nursing
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• v.18 no.3
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• pp.363-372
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• 2007

Purpose: This study is to examine the effects of the drinking-reduction program that utilizes transtheoretical model and leisure ability model on the problem drinking behavior, alcohol outcome expectancy, and abstinence self-efficacy of. problem drinkers at workplaces. Method: The subjects consisted of 54 male problem drinkers who scored over 12 points in the AUDIT-K with 23 persons in the experimental group and 31 persons in the control group. The research results were analyzed using the SAS program with Chi-square test, t-test, repeated ANOVA, and post-hoc comparison. Results: 1) The experimental group showed a significantly lower score in problem drinking behavior than the control group. 2) The experimental group showed a significantly lower score in alcohol outcome expectancy than the control group. 3) The experimental group showed a significantly higher score in abstinence self-efficacy than the control group. Conclusion: These results demonstrate that the drinking-reduction program effectively reduces the drinking behavior of problem drinkers at workplaces, reduces alcohol outcome expectancy, and enhances abstinence self-efficacy. Accordingly, it is considered that a drinking-reduction program can be a useful nursing intervention method for problem drinkers at workplaces to reduce drinking and improve the quality of life.

• Journal of Power Electronics
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• v.10 no.6
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• pp.604-610
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• 2010

Experiments in electrical engineering should mirror the key components of successful research and development: Understand the basic theory needed, test the resulting concepts by simulation and verify these, finally, in the experiment. For optimal learning outcome continuous monitoring of the progress of each individual student is necessary, immediately repeating those subjects which have not been learned successfully. Classically, this is the task of the teacher. In case of remote-controlled experiments this monitoring process and the repetition of subjects should be automated for optimal learning outcome. This paper describes a remote-controlled experiment combining theory, simulation and the experiment itself with an automated monitoring process. Only the evaluation of the experimental results and their comparison to the simulation results has to be checked by a teacher. This paper describes the details of the educational structure for a remote-controlled experiment introducing active filtering of harmonics. For better understanding the content of the learning material (theory and simulation) as well as the results of the experiment and the underlying booking system are shortly presented.

• Parasites, Hosts and Diseases
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• v.51 no.1
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• pp.69-74
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• 2013

Leishmania tropica is one of the causative agents of leishmaniasis in humans. Routes of infection have been reported to be an important variable for some species of Leishmania parasites. The role of this variable is not clear for L. tropica infection. The aim of this study was to explore the effects of route of L. tropica infection on the disease outcome and immunologic parameters in BALB/c mice. Two routes were used; subcutaneous in the footpad and intradermal in the ear. Mice were challenged by Leishmani major, after establishment of the L. tropica infection, to evaluate the level of protective immunity. Immune responses were assayed at week 1 and week 4 after challenge. The subcutaneous route in the footpad in comparison to the intradermal route in the ear induced significantly more protective immunity against L. major challenge, including higher delayed-type hypersensitivity responses, more rapid lesion resolution, lower parasite loads, and lower levels of IL-10. Our data showed that the route of infection in BALB/c model of L. tropica infection is an important variable and should be considered in developing an appropriate experimental model for L. tropica infections.

• Journal of muscle and joint health
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• v.25 no.3
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• pp.205-217
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• 2018

Purpose: The purpose of this review was to analyze the characteristics and effectiveness of online-based intervention for infertile women. Methods: We established the PICO (Participant-Intervention-Comparison-Outcome) strategy and conducted a systematic review of 7 literatures retrieved from 3 electronic databases of Ovid-Medline, Ovid-Embase, and the Cochrane Library. Two investigators independently extracted the data and assessed the quality of included studies using Cochrane risk of bias. Results: The pregnancy outcome showed that higher total risk scores (TRS) about lifestyle behavior was significantly associated with lower chance of pregnancy (aHR 0.79, 95% CI 0.72~0.85). Stress was significantly decreased in experimental groups receiving online-based interventions (p<.05). Depression score was significantly lower in groups receiving additional interventions besides on-line interventions than those who used online-based intervention only. The other outcomes, including anxiety, self-efficacy, helpfulness of intervention, perceived social support, and knowledge scores were not significantly different within and between groups in overall. Characteristics of the interventions were heterogeneous. Conclusion: There is evidence that online-based intervention in infertile women enhances the pregnancy and reduces stress levels.

• Journal of Gastric Cancer
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• v.16 no.4
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• pp.254-259
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• 2016

Purpose: Owing to increased life expectancy, the number of elderly patients with gastric cancer has increased. This study aimed to identify the outcomes of gastric cancer patients aged 80 years or older through comparison of their clinicopathological characteristics, surgical outcomes, and oncologic outcomes. Materials and Methods: Between January 2006 and December 2013, the records of 478 patients who underwent surgery for gastric cancer were retrospectively evaluated. Patients were divided into two groups: patients <80 years old (n=446) and patients ${\geq}80$ years old (n=32). Results: There were no significant differences in sex, body mass index, length of hospital stay, duration of surgery, depth of invasion, nodal metastasis, histologic type, or tumor size between the two groups. However, significant differences were found for the American Society of Anesthesiologist score and the serum albumin level between the two groups. Postoperative morbidity, mortality, disease-free survival, and recurrence rate did not differ between curatively resected patients in the two groups. Conclusions: In elderly patients with gastric cancer, active treatment including radical gastrectomy is necessary.

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.38-39
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• 2003

To evaluate the clinical characteristics and outcome of the patients with disseminated pilocytic astrocytoma compared to non-disseminated disease and to discuss treatment options for disseminated disease. We Identified patients with disseminated pilocytic astrocytoma from our Tumor Registry over 21 years of period and reviewed medical records and neuroimages to determine location of the tumor, pattern of dissemination, clinical characteristics, treatment, and outcome. 24 controls without dissemination, matched for age at diagnosis, tumor histology, and primary location were selected from the same registry and case/control comparison was done using Kaplan-Meier survival analysis.

• Journal of Engineering Education Research
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• v.15 no.6
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• pp.98-102
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• 2012

This paper diagnose subjects and measures the learning ability of students based on the goal of developing an assessment tool for education productivity based on multi-aspect evaluation conducted by ICEE at Honam University. Furthermore, develop an assessment tool for education productivity that provides a motive to bring detailed improvements in teaching methods through the diagnosis. In addition, a method for compensating the issues and improving the quality of subject is suggested to develop learning ability of students through applying the assessment tool. An integrated operated system of CQI is desired to be built along with quality improvement of education through measuring academic quality by studying the methods for enhancing academic and learning ability achievement from analysis of the curriculum provided in the "ABEEK program". Through this study the current state of education productivity is presented through analyzing the difference between students who participated in the "ABEEK program" and who did not participate, and operating a comparison between the student's comprehension on their majors and liberal arts by the multi-aspect evaluation that has been conducted for 2 years.