• Title/Summary/Keyword: Osteopenia

Search Result 180, Processing Time 0.034 seconds

The Difference in Bone metabolism markers and Adipocytokine according to the applying Modern Dance with Osteopenia elderly women

  • Kim, Chan-Yang;Lee, Jin-Wook
    • Journal of the Korea Society of Computer and Information
    • /
    • v.25 no.5
    • /
    • pp.147-158
    • /
    • 2020
  • The purpose of this study is to propose an effective exercise for the prevention of osteoporosis by analyzing changes in bone metabolism markers and adipocytokines according to the application of modern dance. The objects were selected between t-score -1.0 to -2.5 and subjects were random assigned to the modern dance group(n=10) and control group(n=10). Modern dance was held three times a week for 60min, for 12weeks. For data analysis, two-way repeated measures ANOVA was analyzed using SPSS. As a result of the study, both osteocalcin(p<.01) and T-score(p<.05) were significantly increased in the modern dance group. Adiponectin(p<.05) was increased significantly and Both TNF-α (p<.05) and IL-6(p<.05) were significantly decreased in the modern dance group. As a result, modern dance is considered to be an effective strategy to prevent osteoporosis, and it is expected to have a positive effect on metabolism and function improvement in elderly women with osteopenia.

Comparative Study of Anti-osteoporotic Agents in Postmenopausal Women (골다공증 및 골감소증 치료제의 치료효과 비교연구)

  • Kim, Hee Sun;Sohn, Minji;Bang, Joon Seok;Sohn, Uy Dong
    • Korean Journal of Clinical Pharmacy
    • /
    • v.24 no.2
    • /
    • pp.98-105
    • /
    • 2014
  • Purpose: The aim of this study was to compare retrospectively the efficacy of anti-osteoporotic agents (RAL-Raloxifene 60 mg, ALD-weekly alendronate 70 mg, RSD-weekly risedronate 35 mg, AVD3-weekly alendronate 70 mg/vitamin $D_3$ 2800IU, IBD-quarterly IV ibandronate 3 mg/3 ml, ZLD-yearly IV zoledronate 5 mg/100 ml) in postmenopausal patients with osteoporosis or osteopenia. Method: This study retrospectively reviewed medical record and compared the lumbar spine BMD percentage changes of each medicine group one year later from the baseline. 209 patients (27, 50, 60, 30, 35, and 7 patients in RAL, ALD, RSD, AVD3, IBD, and ZLD groups, respectively) are within the inclusion criteria for the study. Results: From baseline to month 12, lumbar spine BMD increased significantly larger with bisphosphonate groups, compared to SERM (p < 0.05). In all bisphosphonate groups, the lumbar spine BMD were increased significantly from baseline. Of the bisphosphonates, the changes from baseline in BMD of IV bisphosphonates were more larger than those of oral bisphosphonates, and yearly, quarterly bisphosphonates yielded significantly greater BMD gains, compared with weekly bisphosphonate groups (p<0.05). In addition, patients receiving 70 mg weekly alendronate+vitamin D3 had greater gains in BMD than alendronate Single preparation (p<0.05). Conclusion: Bisphosphonates yielded significantly greater BMD gains than SERM. Of the bisphosphonates, the changes from baseline in BMD of yearly, quarterly IV bisphosphonates yielded significantly greater BMD gains, compared with weekly oral bisphosphonate groups. In addition, vitamin D3 plays an significant role in BMD gains.

Analysis of Bone Mineral Density, Biochemical Index and Nutrient Intakes of 30-70 Years Old Women -Based on 2011 KNHANES- (30~70대 여성의 골밀도, 생화학적 특성 및 영양소 섭취 분석 -2011년 국민건강영양조사를 중심으로-)

  • Koo, Jae Ok;Kim, Myung Sook
    • Korean Journal of Community Nutrition
    • /
    • v.19 no.4
    • /
    • pp.328-341
    • /
    • 2014
  • Objectives: This study was carried out to investigate bone mineral density (BMD), blood pressure, age and biochemical index and nutrient intakes, and to analyze the relationship between BMD, blood pressure, biochemical index, nutrient intakes of Korean women. Methods: The study subjects were 499 women with a age range of 30-79 years living in Seoul and Kyunggi area who participated in 2011 KNHANES. The study subjects were divided into 5 age groups : 30 years (145), 40 years (110), 50 years (102), 60 years (85) and 70 years (57), and 3 BMD groups: normal 258 (50.4%), osteopenia 163 (32.9%) and osteoporosis 78 (16.7%). Results: The average waist circumference, BMI and body fat increased with age, but fat free mass decreased with age. Average BMD and T-score was decreased from 0.84, $0.74g/cm^2$ in 30 years to 0.05, $-1.05g/cm^2$ in 70 years. The rates of osteopenia and osteoporosis increased significantly 22% in 30~40 years, 47% in 50 years and 56% in 60~70 years. Systolic blood pressure and cholesterol were significantly increased with age. The rates of hypertension was significantly increased 2.1% in 30 years, 30.4% in 50 years 89.5% in 70 years. Average nutrient intakes such as protein, calcium, iron, vitamin A and C were significantly decreased with age. There were significant negative correlations between age and calcium, systolic blood pressure, triglyceride. Conclusions: In this study, we found the risk of osteoporosis and hypertension were significantly increase with over 50 years age. Calcium and protein intake decreased with age. Therefore, in order to prevent osteoporosis and hypertension, adult women need to be educated regarding the importance of protein, calcium and other nutrients in their diet.

Relationship between the number of remaining teeth and bone health status among the elderly in Korea (한국 노인의 현존치아수와 골 건강상태와의 연관성)

  • Cho, Youn-Young
    • Journal of Korean society of Dental Hygiene
    • /
    • v.18 no.2
    • /
    • pp.205-215
    • /
    • 2018
  • Objectives: The purpose of the study is to investigate the relationship between the number of remaining teeth and bone health status among adults over 65 years old. Methods: The study subjects were 1,843 adults over 65 years old drawn from the Korea National Health and Nutrition Examination Survey (KNHANES) in 2008-2010. Oral health status included the number of remaining teeth, and prosthetic appliance status. Bone health statuses were assessed using dual-energy X-ray absorptiometry (DEXA). Bone health statuses were classified into normal (T-score ${\geq}-1.0$), osteopenia (-2.5 < T-score < -1.0), and osteoporosis (T-score ${\leq}-2.5$). Complex samples chi-square test was used to estimate the relationship between the number of remaining teeth and bone health status, and related factors included in the model were analyzed with the complex samples logistic regression analysis. Results: Using the multinomial logistic regression analytic method, the elderly having 20 or more remaining teeth and those having less than 20 remaining teeth with prosthesis were compared. The latter group had 1.89 times higher rate of being diagnosed as having osteoporosis. Conclusions: This study suggests that oral health is an important factor for geriatric osteoporosis. Therefore, in order to prevent fractures due to osteoporosis and osteoporosis in old age, it is necessary to be aware of the relationship between oral health and osteoporosis, and oral health should be considered when preparing preventive management strategies.

Nutritional Status and Related Factors of Residents Aged Over 50 in Longevity Areas - II, Effect of Dietary Factors on Bone Ultrasound Measurements in Aged Men - (고령인구 비율이 높은 지역 장년, 노년층의 건강.영양상태 및 이에 영향을 미치는 인자에 관한 연구 - II. 남자의 골밀도와 이에 영향을 미치는 식이요인분석 -)

  • Choe Jeong-Sook;Kwon Sung-Ok;Paik Hee-Young
    • Journal of Nutrition and Health
    • /
    • v.39 no.2
    • /
    • pp.171-183
    • /
    • 2006
  • This study was conducted to examine dietary factors affecting bone status in the rural aged men. Quantitative ultrasound measurements (QUS) of bone, that may reflect certain architectural aspects of bone, have been shown to be associated with bone mineral density and fracture. Information of diet and anthropometry was collected in 164 aged men. Dietary intake data were obtained by 24-hour recall method. Measurements of the speed of sound (SOS, m/s), at distal radius, mid-tibia, phalanx, were performed using Omnisense 7000S analyzer (Sunlight Ltd., Tel Aviv, Israel). T-scores for bone SOS measurements at distal radius, mid-tibia and phalanx were 0.60, 0.03 and -0.42 respectively. The prevalence of osteopenia by use of the WHO criteria was 17.7% at the mid-tibia and 25.3% of the subjects at the distal radius. Age were negative association with bone SOS at three sites. Osteopenia group of radius were significantly lower in total foods and vegetable intakes than normal group. After adjusted for age, vegetable intakes were significantly and positively related to bone SOS at the radius. The bone SOS of the tibia were significantly and positively related to vegetable protein, iron, folate and vegetable intakes, but negatively related to fat intakes. Multiple regression analysis showed that bone SOS of tibia was positively associated with folate intakes. Vegetable intakes were positively associated with the bone SOS at three sites. These results indicate that the consumption of vegetables, sources of folate, may have a effect on bone status of men.

Numerical Stress Analysis of bone plate System using 3-dimensional finite element method (3차원 유한 요소법을 이용한 골절판의 응력 해석)

  • Kim, Hyun-Su;Kwon, Young-Soo
    • Proceedings of the KOSOMBE Conference
    • /
    • v.1991 no.05
    • /
    • pp.74-78
    • /
    • 1991
  • Conventional compression bone fracture plates sometimes cause osteoporosis under the plate due to their high rigidity which in turn transfer physiological load mostly through the plates and screws. In order to prevent the osteopenia we have designed a system which have a viscoelastic washer between plate and screw head. The washer is made of a biocompatible ploymer (untra high molecular weight polyethylene, UHMWPE). Three-dimensional finite element meshes of the human femur with the conventional and new concept bone plate ere generated and the comparative stress analyses are performed with static half-stance loading condition. The results of analyses showed that could reduce the stress shielding effect compared with the conventional plate.

  • PDF

A Study on the Life Style and Bone Mineral Density of Women College Students by Body Mass Index (체질량지수에 따른 여대생의 생활습관과 골밀도에 대한 연구)

  • Kim Ju-Nam;Seo Ji-Hyung
    • Food Industry And Nutrition
    • /
    • v.9 no.2
    • /
    • pp.41-45
    • /
    • 2004
  • 대학생들의 신체상태와 생활습관 조사를 통해 이들의 상관관계를 비교·분석 한 결과, 정상체중군의 평균 신장과 체중은 각각 163.75 cm, 56.07 kg이었다. 조사대상자중 체중과다는 29.1%였고, 특히 과체중군과 비만군의 체지방율 및 복부비만도는 정상군과 유의적인 차이 가 인정되었다. 저체중군중 13.3%가 흡연경험 및 흡연중으로 답해 여대생의 흡연문제가 심각하였으며, 조사대상자중 81.8%가 운동을 거의 않거나 운동횟수가 불규칙한 것으로 나타났다. 저체중군을 제외 한 다른 모든 군에서 50% 이상이 '아침을 자주 거른다'고 하였으며, 과체중군과 비만군의 경우 응답자 전원이 가끔 혹은 자주 간식을 먹고 있다고 하였다 조사군의 1일 평균 칼슘섭취량은 400mg수준이었으며, 저체중군은 T값이 -1 이 하로 골감소(osteopenia)증상이 우려되었다.

  • PDF

The Precision Test Based on States of Bone Mineral Density (골밀도 상태에 따른 검사자의 재현성 평가)

  • Yoo, Jae-Sook;Kim, Eun-Hye;Kim, Ho-Seong;Shin, Sang-Ki;Cho, Si-Man
    • The Korean Journal of Nuclear Medicine Technology
    • /
    • v.13 no.1
    • /
    • pp.67-72
    • /
    • 2009
  • Purpose: ISCD (International Society for Clinical Densitometry) requests that users perform mandatory Precision test to raise their quality even though there is no recommendation about patient selection for the test. Thus, we investigated the effect on precision test by measuring reproducibility of 3 bone density groups (normal, osteopenia, osteoporosis). Materials and Methods: 4 users performed precision test with 420 patients (age: $57.8{\pm}9.02$) for BMD in Asan Medical Center (JAN-2008 ~ JUN-2008). In first group (A), 4 users selected 30 patient respectively regardless of bone density condition and measured 2 part (L-spine, femur) in twice. In second group (B), 4 users measured bone density of 10 patients respectively in the same manner of first group (A) users but dividing patient into 3 stages (normal, osteopenia, osteoporosis). In third group (C), 2 users measured 30 patients respectively in the same manner of first group (A) users considering bone density condition. We used GE Lunar Prodigy Advance (Encore. V11.4) and analyzed the result by comparing %CV to LSC using precision tool from ISCD. Check back was done using SPSS. Results: In group A, the %CV calculated by 4 users (a, b, c, d) were 1.16, 1.01, 1.19, 0.65 g/$cm^2$ in L-spine and 0.69, 0.58, 0.97, 0.47 g/$cm^2$ in femur. In group B, the %CV calculated by 4 users (a, b, c, d) were 1.01, 1.19, 0.83, 1.37 g/$cm^2$ in L-spine and 1.03, 0.54, 0.69, 0.58 g/$cm^2$ in femur. When comparing results (group A, B), we found no considerable differences. In group C, the user_1's %CV of normal, osteopenia and osteoporosis were 1.26, 0.94, 0.94 g/$cm^2$ in L-spine and 0.94, 0.79, 1.01 g/$cm^2$ in femur. And the user_2's %CV were 0.97, 0.83, 0.72 g/$cm^2$ L-spine and 0.65, 0.65, 1.05 g/$cm^2$ in femur. When analyzing the result, we figured out that the difference of reproducibility was almost not found but the differences of two users' several result values have effect on total reproducibility. Conclusions: Precision test is a important factor of bone density follow up. When Machine and user's reproducibility is getting better, it’s useful in clinics because of low range of deviation. Users have to check machine's reproducibility before the test and keep the same mind doing BMD test for patient. In precision test, the difference of measured value is usually found for ROI change caused by patient position. In case of osteoporosis patient, there is difficult to make initial ROI accurately more than normal and osteopenia patient due to lack of bone recognition even though ROI is made automatically by computer software. However, initial ROI is very important and users have to make coherent ROI because we use ROI Copy function in a follow up. In this study, we performed precision test considering bone density condition and found LSC value was stayed within 3%. There was no considerable difference. Thus, patient selection could be done regardless of bone density condition.

  • PDF

Osteoporosis in Chronic Obstructive Pulmonary Disease (만성폐쇄성폐질환에서의 골다공증에 관한 연구)

  • Kim, Seong-Ja;Lee, Young-Hyun
    • Tuberculosis and Respiratory Diseases
    • /
    • v.47 no.1
    • /
    • pp.90-96
    • /
    • 1999
  • Background : Osteoporosis has been reported in patients with chronic obstructive pulmonary disease, but this association is not well established. This study was undertaken to determine whether the prevalence of osteoporosis was increased in patients with chronic obstructive pulmonary disease and we examined the relationship of corticosteroid administration with osteoporosis. Method: Subjects were 23 patients with chronic obstructive pulmonary disease and 20 control patients. We reviewed hospital records and measured bone mineral density using dual-energy x-ray absorptiometry(Lunar. USA). Results: Mean bone mineral density(BMD) of spine in COPD group was $0.683{\pm}0.154 g/cm^2$ and $0.971{\pm}0.212g/cm^2$ in controls(p<0.01). But there was no significant difference in femoral neck BMD. There were seventeen cases of osteoporosis and six cases of osteopenia in COPD group and three patients of osteoporosis and one case of osteopenia in controls. But, there was no significant correlation between disease duration of COPD and spinal T score(r=-0.395, p>0.05). Ten patients were received corticosteroid in COPD group. Spinal T score in steroid receiving patients were $-3.82{\pm}0.94(SD)$ and $-2.82{\pm}0.97(SD)$ in not having steroid patients(p<0.01). Cumulative dose of corticosteroid was associated with spinal T score(r=-0.424, p<0.05) and duration of corticosteroid administration also associated with spinal T score(r=-0.457. p<0.05). Spinal BMD of patients not having corticosteroid in COPD group(n=13) were significantly lower than that of controls($0.71{\pm}0.13 g/cm^2$ and $0.97{\pm}0.21 g/cm^2$, p<0.01). Conclusion : Prevalence of osteoporosis is increased in patients with chronic obstructive pulmonary disease. Especially patients who are receiving corticosteroid have high risk of osteoporosis or osteopenia and need for preventive management.

  • PDF

Relationships of Changing Social Atmosphere, Lifestyle and Bone Mineral Density in College Students (대학생의 골밀도와 사회분위기 및 생활습관과의 관계)

  • Lee, In-Ja;Ko, Yo-Han;Kim, Chung-Kyung;Kim, Hee-Sol;Park, Da-Jeong;Yoon, Hyeo-Min;Jeong, Yu-Jin
    • Journal of radiological science and technology
    • /
    • v.36 no.4
    • /
    • pp.263-271
    • /
    • 2013
  • The decrease of bone mineral density gives rise to the outbreak of osteopenia and makes the possibility of a bone fracture. It makes health problems in society. It's very important to prevent osteopenia in advance. Also it's critical to prevent and take care of it in adolescent because it's the most developing period comparing to middle ages because that bone mineral density decreases. There are genetic, physical and enviromental factors that affect bone mineral density. Recently, a lifestyle and eating habits are also changing as the society atmosphere is gradually doing. This study have shown that 134 women and 75 men was chosen and responded to the survey of measuring bone mineral density and investigating a lifestyle. The measure of bone mineral density is to use Dual energy X-ray absorptiometry(DEXA) and check femoral neck and lumbar spine. Also questionaries was required to pre-made survey about their lifestyles. Analysis of data was done with SPSS program. Multiple regression analysis was used for the relation of bone mineral density, the heigths and BMI. The sample of Groups are checked for drinking, smoking or excercising about differences by t-test. The results of the experiments were; first, there is statistically significant differences in the comparisons between BMD and BMD. But there isn't any special correlation between drinking, smoking and BMD. Secondly, bone mineral density becomes low related to an intake of caffeine. Particularly, this is statically significant on women. Also there is statically significant correlation between femoral neck and quantity of motion for both men and women. Third, there is significant relation between eating habits and bone mineral density on women's lumbar spine. However, there is no significant relation between men's lumbar spine and women's one. Therefore, to prevent osteopenia, it's good to abstain from intaking caffeine within an hour after a meal. In addition, it's helpful to walk or run regularly and have a balanced meal.