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http://dx.doi.org/10.9708/jksci.2020.25.05.147

The Difference in Bone metabolism markers and Adipocytokine according to the applying Modern Dance with Osteopenia elderly women  

Kim, Chan-Yang (School of Kinesiologic Medical Science, Dankook University)
Lee, Jin-Wook (Dept of Exercise Prescription Rehabilitation, Dankook University)
Abstract
The purpose of this study is to propose an effective exercise for the prevention of osteoporosis by analyzing changes in bone metabolism markers and adipocytokines according to the application of modern dance. The objects were selected between t-score -1.0 to -2.5 and subjects were random assigned to the modern dance group(n=10) and control group(n=10). Modern dance was held three times a week for 60min, for 12weeks. For data analysis, two-way repeated measures ANOVA was analyzed using SPSS. As a result of the study, both osteocalcin(p<.01) and T-score(p<.05) were significantly increased in the modern dance group. Adiponectin(p<.05) was increased significantly and Both TNF-α (p<.05) and IL-6(p<.05) were significantly decreased in the modern dance group. As a result, modern dance is considered to be an effective strategy to prevent osteoporosis, and it is expected to have a positive effect on metabolism and function improvement in elderly women with osteopenia.
Keywords
Modern dance; Ostocalcin; Adiponectin; $TNF-{\alpha}$; IL-6; Adipocytokine;
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1 S. Barene, P. Krustrup, O. L. Brekke, and A. Holtermann, "Soccer and Zumba as health-promoting activities among female hospital employees: a 40-weeks cluster randomised intervention study," Journal of sports sciences, Vol. 32, No. 16, pp. 1539-1549, April 2014. DOI: 10.1080/02640414.2014.906043   DOI
2 P. D. Delmas, D. E. B. R. A. Stenner, H. W. Wahner, K. G. Mann, and B. L. Riggs, "Increase in serum bone gamma-carboxyglutamic acid protein with aging in women. Implications for the mechanism of age-related bone loss," The Journal of clinical investigation, Vol. 71, No. 5, pp. 1316-1321, May 1983. DOI: 10.1172/jci110882   DOI
3 M. M. Saunders, A. F. Taylor, C. Du, Z. Zhou, V. D. Pellegrini Jr, and H. J. Donahue, "Mechanical stimulation effects on functional end effectors in osteoblastic MG-63 cells," Journal of biomechanics, Vol. 39, No. 8, pp. 1419-1427, June 2005. DOI: 10.1016/j.jbiomech.2005.04.011   DOI
4 Y. Koutedakis, A. Stavropoulos-Kalinoglou, and G. Metsios, "The significance of muscular strength in dance," Journal of dance medicine & science, Vol. 9, No. 1, pp. 29-34, November 2005. https://www.researchgate.net/profile/Yiannis_Koutedakis/publication/32117167_The_Significance_of_Muscular_Strength_in_Dance/links/571baa6d08aee3ddc569dfe8.pdf
5 M. G. S. Amorim, M. D. de Oliveira, D. S. Soares, L. da Silva Borges, A. Dermargos, and E. Hatanaka, "Effects of exergaming on cardiovascular risk factors and adipokine levels in women," The Journal of Physiological Sciences, Vol. 68, No. 5, pp. 671-678, September 2018. DOI: 10.1007/s12576-017-0581-5   DOI
6 Y. Zhang, P. Zhou, and J. W. Kimondo, "Adiponectin and osteocalcin: relation to insulin sensitivity," Biochemistry and Cell Biology, Vol. 90, No. 5, pp. 613-620, October 2012. DOI: 10.1139/o2012-022   DOI
7 D. Naot, M. Watson, K. E. Callon, D. Tuari, D. S. Musson, A. J. Choi, ... and G. D. Gamble, "Reduced bone density and cortical bone indices in female adiponectin-knockout mice," Endocrinology, Vol. 157, No. 9, pp. 3550-3561, September 2016. DOI: 10.1210/en.2016-1059   DOI
8 M. Ferron, E. Hinoi, G. Karsenty, and P. Ducy, "Osteocalcin differentially regulates ${\beta}$ cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice," Proceedings of the National Academy of Sciences, Vol. 105, No. 13, pp. 5266-5270, April 2008. DOI: 10.1073/pnas.0711119105   DOI
9 E. A. Greco, D. Francomano, R. Fornari, C. Marocco, C. Lubrano, V. Papa, ... and A. Aversa, "Negative association between trunk fat, insulin resistance and skeleton in obese women," World journal of diabetes, Vol. 4, No. 2, pp. 31, April 2013. DOI: 10.4239/wjd.v4.i2.31   DOI
10 H. J. Kim, "New understanding of glucocorticoid action in bone cells," BMB reports, Vol. 43, No. 8 pp. 524-529, August 2010. DOI: 10.5483/bmbrep.2010.43.8.524   DOI
11 L. E. Polgreen, D. R. Jacobs Jr, B. M. Nathan, J. Steinberger, A. Moran, and A. R. Sinaiko, "Association of osteocalcin with obesity, insulin resistance, and cardiovascular risk factors in young adults," Obesity, Vol. 20, No. 11, pp. 2194-2201, November 2012. DOI: 10.1038/oby.2012.108   DOI
12 J. Wei, T. Hanna, N. Suda, G. Karsenty, and P. Ducy, "Osteocalcin promotes ${\beta}$-cell proliferation during development and adulthood through Gprc6a," Diabetes, Vol. 63, No. 3, pp. 1021-1031, March 2014. DOI: 10.2337/db13-0887   DOI
13 M. L. Zoch, T. L. Clemens, and R. Riddle, "New insights into the biology of osteocalcin," Bone, Vol. 82, pp. 42-49, January 2016. DOI: 10.1016/j.bone.2015.05.046   DOI
14 K. Baek, "An overview of the endocrine functions of osteocalcin," International Journal of Oral Biology, Vol. 44, No. 4, pp. 125-129, August 2019. DOI : https://doi.org/10.11620/IJOB.2019.44.4.125   DOI
15 J. H. Kang, "Association of Serum Osteocalcin with Metabolic Syndrome in Korean Adult Women," Korean J Health Promot, Vol. 17, No. 3, pp. 145-151, September 2017. DOI : 10.15384/kjhp.2017.17.3.145   DOI
16 G. Fantuzzi, "Adiponectin in inflammatory and immune-mediated diseases," Cytokine, Vol. 64, No. 1, pp. 1-10, July 2013. DOI: 10.1016/j.cyto.2013.06.317   DOI
17 K. Oshima, A. Nampei, M. Matsuda, M. Iwaki, A. Fukuhara, J. Hashimoto, ... and I. Shimomura, "Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast," Biochemical and biophysical research communications, Vol. 331, No. 2, pp. 520-526, June 2005. DOI: 10.1016/j.bbrc.2005.03.210   DOI
18 D. Suksom, Y. Phanpheng, S. Soogarun, and S. Sapwarobol, "Step aerobic combined with resistance training improves cutaneous microvascular reactivity in overweight women," The Journal of sports medicine and physical fitness, Vol. 55, No. 12, pp. 1547-1554, December 2015. PMID: 25303169
19 E. C. Murphy, L. Carson, W. Neal, C. Baylis, D. Donley, and R. Yeater, "Effects of an exercise intervention using Dance Dance Revolution on endothelial function and other risk factors in overweight children," International Journal of Pediatric Obesity, Vol. 4, No. 4, pp. 205-214, February 2009. DOI: 10.3109/17477160902846187   DOI
20 D. K. Oh, T. Ciaraldi, and R. R. Henry, "Adiponectin in health and disease," Diabetes, obesity and metabolism, Vol. 9, No. 3, pp. 282-289, May 2007. DOI: 10.1111/j.1463-1326.2006.00610.x   DOI
21 S. Khosla, "Minireview: The opg/rankl/rank system," Endocrinology, Vol. 142, No. 12, pp. 5050-5055, December 2001. DOI: 10.1210/endo.142.12.8536   DOI
22 J. Vendrell, M. Broch, N. Vilarrasa, A. Molina, J. M. Gomez, C. Gutierrez, ... and C. Richart, "Resistin, adiponectin, ghrelin, leptin, and proinflammatory cytokines: relationships in obesity," Obesity research, Vol. 12, No. 6, pp. 962-971, June 2004. DOI: 10.1038/oby.2004.118   DOI
23 J. Pfeilschifter, R. Koditz, M. Pfohl, and H. Schatz, "Changes in proinflammatory cytokine activity after menopause," Endocrine reviews, Vol. 23, No. 1, pp. 90-119. February 2002. DOI: 10.1210/edrv.23.1.0456   DOI
24 T. E. Van Dyke, and C. N. Serhan, "Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases," Journal of dental research, Vol. 82, No. 2, pp. 82-90, February 2003. DOI: 10.1177/154405910308200202   DOI
25 G. R. Mundy, "Osteoporosis and inflammation," Nutrition reviews, 65(suppl_3), S147-S151, December 2007. DOI: 10.1111/j.1753-4887.2007.tb00353.x   DOI
26 A. Patti, L. Gennari, D. Merlotti, F. Dotta, and R. Nuti, "Endocrine actions of osteocalcin," International journal of endocrinology, April 2013. DOI: 10.1155/2013/846480
27 I. Kanazawa, "Osteocalcin as a hormone regulating glucose metabolism," World journal of diabetes, Vol. 6, No. 18, pp. 1345, December 2015. DOI: 10.4239/wjd.v6.i18.1345   DOI
28 T. Kadowaki, and T. Yamauchi, "Adiponectin and adiponectin receptors," Endocr Rev Vol. 26, pp.439-451, May 2005. DOI: 10.1210/er.2005-0005   DOI
29 C. M. Steppan, D. T. Crawford, K. L. Chidsey-Frink, H, Ke, and A. G. Swick, "Leptin is a potent stimulator of bone growth in ob/ob mice," Regulatory peptides, Vol. 92, No.1-3, pp. 73-78, August 2000. DOI: 10.1016/s0167-0115(00)00152-x   DOI
30 H. Tilg, and A. Moschen, "Inflammatory mechanisms in the regulation of insulin resistance," Mol Med Vol. 14, No. 3-4, pp. 222-231, March-Amril 2008. DOI: 10.2119/2007-00119.Tilg   DOI
31 P. Magni, E. Dozio, E. Galliera, M. Ruscica, and M. M. Corsi, "Molecular aspects of adipokine-bone interactions," Current molecular medicine, Vol. 10, No. 6, pp. 522-532, August 2010. DOI: 10.2174/1566524011009060522   DOI
32 World Health Organization, "WHO Scientific Group on Prevention, Management of Osteoporosis, & World Health Organization," Prevention and management of osteoporosis: report of a WHO scientific group, No. 921, 2003.
33 G. A. Borg, "Psychophysical bases of perceived exertion," Medicine & Science in Sports & Exercise. Vol. 14, No. 5, pp. 377-381, 1982. https://doi.org/10.1249/00005768-198205000-00012
34 S. Ertek, and A. Cicero, "Impact of physical activity on inflammation: effects on cardiovascular disease risk and other inflammatory conditions," Archives of medical science: AMS, Vol. 8, No. 5, pp. 794-804, November 2012. DOI: 10.5114/aoms.2012.31614
35 L. Borges, M. E. Passos, M. B. Silva, V. C. Santos, C. M. Momesso, T. C. Pithon-Curi, ... and E. Hatanaka, "Dance Training Improves Cytokine Secretion and Viability of Neutrophils in Diabetic Patients," Mediators of Inflammation, November 2019. DOI: 10.1155/2019/2924818
36 P. A. Domene, H. J. Moir, E. Pummell, A. Knox, and C. Easton, "The health-enhancing efficacy of Zumba(R) fitness: An 8-week randomised controlled study," Journal of sports sciences, Vol. 34, No. 15, pp. 1396-1404, August 2016. DOI: 10.1080/02640414.2015.1112022   DOI
37 H. Aleman, J. Esparza, F. A. Ramirez, H. Astiazaran, and H. Payette, "Longitudinal evidence on the association between interleukin-6 and C-reactive protein with the loss of total appendicular skeletal muscle in free-living older men and women," Age and ageing, Vol. 40, No. 4, pp. 469-475, July 2011. DOI: 10.1093/ageing/afr040   DOI
38 M. A. Nimmo, M. Leggate, J. L. Viana, and J. A. King, "The effect of physical activity on mediators of inflammation," Diabetes, Obesity and Metabolism, Vol. 15(s3), pp. 51-60, September 2013. DOI: 10.1111/dom.12156   DOI
39 R. Belardinelli, F. Lacalaprice, C. Ventrella, L. Volpe, and E. Faccenda, "Waltz dancing in patients with chronic heart failure: new form of exercise training," Circulation: Heart Failure, Vol. 1, No. 2, pp. 107-114, July 2008. DOI: 10.1161/CIRCHEARTFAILURE.108.765727   DOI
40 M. G. Lee, K. S. Park, D. U. Kim, S. M. Choi, and H. J. Kim, "Effects of high-intensity exercise training on body composition, abdominal fat loss, and cardiorespiratory fitness in middle-aged Korean females," Applied Physiology, Nutrition, and Metabolism, Vol. 37, No. 6, pp. 1019-1027, December 2012. DOI: 10.1139/h2012-084   DOI
41 B. Dawson-Hughes, A. N. A. Tosteson, L. 3. Melton, S. Baim, M. J. Favus, S. Khosla, and R. L. Lindsay, "Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA," Osteoporosis International, Vol. 19, No. 4, pp. 449-458, April 2008. DOI: 10.1007/s00198-008-0559-5   DOI
42 G. J. Baek, and J. Y. Ha, "Effects of Line Dance and Walking on Cardiovascular Risk Factors in Obese Older Women," Global Health Nurs, Vol. 10, No.1, pp. 4-13, January 2020. DOI: 10.35144/ghn.2020.10.1.4
43 C. S. In, M. K. Lee. and J. S. Kim, "Effects of motion beat training during dance sport on cardiorespiratory functions, metabolic risk factors and energy regulation hormones in middle-aged women," The Korean Journal of Physical Education, Vol. 55, No. 1, pp. 701-713, January 2016.
44 J. E. Oh, "The effects of Participation in dance sport on health related fitness and bone mineral density in the elderly woman". unpublished a master's thesis, Korea National Sport University. February 2011
45 K. S. Park, J. I. Yoo, H. Y. Kim, S. Jang, Y. Park, and Y. C. Ha, "Education and exercise program improves osteoporosis knowledge and changes calcium and vitamin D dietary intake in community dwelling elderly," BMC public health, Vol. 17, No. 1, pp. 966, December 2017. DOI: 10.1186/s12889-017-4966-4   DOI
46 Statistics Korea, "Future population special estimate. Seoul: Statistics," Retrieved March 5, 2018. http://kostat.go.kr/portal/korea/kor_nw/1/1/index.board
47 B,\. Ettinger, D. M. Black, B. Dawson-Hughes, A. R. Pressman, and L. J. Melton, "Updated fracture incidence rates for the US version of FRAX(R)," Osteoporosis international, Vol. 21, No. 1, pp. 25-33, January 2010. DOI: 10.1007/s00198-009-1032-9   DOI
48 J. A. Kanis, H. Johansson, A. Oden, B. Dawson-Hughes, L. J. Melton, and E. V. McCloskey, "The effects of a FRAX(R) revision for the USA," Osteoporosis international, Vol. 21, No. 1, pp. 35, January 2010. DOI: 10.1007/s00198-009-1033-8   DOI
49 H. K. Kamel, and C. J. Z. Vamc, "FALLS 'GUIDELINES AND OSTEOPOROSIS ASSESSMENT," Journal of the American Geriatrics Society, Vol. 50, No. 6, pp. 1167-1168, June 2002. DOI: 10.1046/j.1532-5415.2002.502831.x   DOI
50 N. Apostolopoulos, G. S. Metsios, A. D. Flouris, Y. Koutedakis, and M. A. Wyon, "The relevance of stretch intensity and position-a systematic review," Frontiers in psychology, Vol. 6, 1128. August 2015. DOI: 10.3389/fpsyg.2015.01128   DOI
51 M. G. Sweet, J. M. Sweet, M. P. JereMiah, and S. S. Galazka, S. S. "Diagnosis and treatment of osteoporosis," American family physician, Vol. 79, No. 3, pp. 193-200, February 2009. https://www.aafp.org/afp/2009/0201/p193.html
52 K. C. Jo, "Theory and facts of dance sports II" seoul, HangKyoung, 2000.
53 A. D. Kriketos, T. A. Sharp, H. M. Seagle, J. C. Peters, and J. O. Hill, "Effect for aerobic fitness on fat oxidation and body fatness," Medicine & Sciencein, Sports & Exercise, Vol. 32, No. 4, pp. 805-811, September 2000. DOI: 10.1159/000357338   DOI
54 L. A. Talbot, C. J. Metter, and J. I. Fleg, "Leisure-time physical activities and their relationship to cardiorespiratory fitness in healthy men and woman 19-95 years old," Medicine in Sports & Exercise, Vol. 32, No. 2, pp. 417-425, February 2000. DOI: 10.1097/00005768-200002000-00024   DOI
55 N. A. Sims, and C. Vrahnas, "Regulation of cortical and trabecular bone mass by communication between osteoblasts, osteocytes and osteoclasts," Archives of biochemistry and biophysics, Vol. 1, No. 561, pp. 22-28, November 2014. DOI: 10.1016/j.abb.2014.05.015
56 S. E. Kim, and S. H. Yang, "The Effect of 12-Week Dance Sports of Body Composition, Daily Living Fitness, Blood Lipid in the Old Age Elderly Women," The Korean Journal of Sport, Vol. 15, No. 2, pp. 645-654, June 2017. http://lps3.www.earticle.net.libproxy.dankook.ac.kr/Article/A304209
57 H. S. Roh, "The Effect of Dance sports on Osteosarcopenic obesity index, Body composition in post menopause obesity," Official Journal of Korean Society of Dance Science, Vol. 35, No. 4, pp. 173-182, October 2018 DOI : 10.21539/ksds.2018.35.4.173
58 W. A. Peck, "Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis," Am J Med, Vol. 94, No. 6, pp. 646-650, Jun 1993. DOI: 10.1016/0002-9343(93)90218-e   DOI
59 A. Klibanski, L. Adams-Campbell, T. L. Bassford, S. N. Blair, S. D. Boden, K. Dickersin, ... and S. R. Johnson, "Osteoporosis prevention, diagnosis, and therapy," Journal of the American Medical Association, Vol. 285, No. 6, pp. 785-795, February 2001. DOI: 10.1001/jama.285.6.785   DOI
60 M. C. Walsh, N. Kim, Y. Kadono, J. Rho, S. Y. Lee, J. Lorenzo, and Y. Choi, "Osteoimmunology: interplay between the immune system and bone metabolism," Annu. Rev. Immunol., Vol. 24, pp. 33-63, October 2005. DOI: 10.1146/annurev.immunol.24.021605.090646   DOI
61 T. Katsumata, T. Nakamura, H. Ohnishi, and T. Sakurama, "Intermittent cyclical etidronate treatment maintains the mass, structure and the mechanical property of bone in ovariectomized rats," Journal of Bone and Mineral Research, Vol. 10, No. 6, pp. 921-931, June 1995. DOI: 10.1002/jbmr.5650100613   DOI
62 T. E. Howe, B. Shea, L. J. Dawson, F. Downie, A. Murray, C. Ross, ... and G. Creed, "Exercise for preventing and treating osteoporosis in postmenopausal women," Cochrane database of systematic reviews, No. 7, July 2011. DOI: 10.1002/14651858.CD000333.pub2
63 J. Farr, J. Rowsey, B. Eckhardt, B. Thicke, D. Fraser, T. Tchkonia, J. Kirkland, D. Monroe, and S. Khosla, "Independent roles of estrogen deficiency and cellular senescence in the pathogenesis of Osteoporosis: Evidence in young adult mice and older humans" Journal of Bone and Mineral Research, Vol. 34, No. 8, pp. 1407-1418, Jun 2019. DOI: 10.1002/jbmr.3729   DOI
64 J. Li. X. Chen, L. Lu. and X. Yu, "The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis," Cytokine & Growth Factor Reviews, Vol. 52, pp. 88-98, February 2020. DOI: 10.1016/j.cytogfr.2020.02.003   DOI
65 H. H. Lee, M. A. Han, J. Park, "Association between Metabolic Syndrome and Osteoporosis in Korean Adults Aged Over 50 Years Old Using the Korea National Health and Nutrition Examination Survey 2016-2017," J Health Info Stat, Vol. 44, No. 3, pp. 245-252, July 2019. DOI: https://doi.org/10.21032/jhis.2019.44.3.245   DOI
66 D. V. Novack, and S. L. Teitelbaum, "The osteoclast: friend or foe?," Annu. Rev. Pathol. Mech. Dis, Vol. 3, pp. 457-484, October 2007. DOI:10.1146/annurev.pathmechdis.3.121806.151431
67 M. Rahim, F. K. Ooi, and W. Z. W. A. Hamid, "Changes of bone metabolism markers and muscular performance with combined aerobic dance exercise and honey supplementation in adult women," Sport Exerc Med Open J, Vol. 1, No. 6, pp. 186-197. April 2016. DOI: 10.17140/SEMOJ-1-129   DOI
68 J. Rittweger, "Can exercise prevent osteoporosis?," Journal of Musculoskeletal and Neuronal Interactions, Vol. 6, No. 2, pp. 162-166, April-June 2006. http://www.ismni.org/jmni/pdf/24/11RITTWEGER.pdf
69 F. A. Schulte, D. Ruffoni, F. M. Lambers, D. Christen, D. J. Webster, G. Kuhn, and R. Müller, "Local mechanical stimuli regulate bone formation and resorption in mice at the tissue level," PloS one, Vol. 8, No. 4, e62172, April 2013. DOI: 10.1371/journal.pone.0062172   DOI
70 J. Rodrigues-Krause, J. B. Farinha, T. R. Ramis, R. C. O. Macedo, F. P. Boeno, G. C. dos Santos, ... and R. S. Pinto, "Effects of dancing compared to walking on cardiovascular risk and functional capacity of older women: A randomized controlled trial," Experimental gerontology, Vol. 114, pp. 67-77, December 2018. DOI: 10.1016/j.exger.2018.10.015   DOI
71 J. Qin, X. Rong, G. Zhu, and Y. Jiang, "The Effects of Square Dancing on Bone Mineral Density and Bone Turnover Markers in Patients with Postmenopausal Osteoporosis," Journal of Mechanics in Medicine and Biology, Vol. 18, No. 8, pp. 18400279(8page), November 2018. DOI: 10.1142/S0219519418400274
72 J. Qin, X. Rong, G. Zhu, and Y. Jiang, "The Effects of Square Dancing on Bone Mineral Density and Bone Turnover Markers in Patients with Postmenopausal Osteoporosis," Journal of Mechanics in Medicine and Biology, Vol. 18, No. 8, pp. 8, November 2018. DOI: 10.1142/S0219519418400274
73 X. Han, S. Gong, N. Li, X. Wang, P. Liu, Y. Xu, X. He, W. Jiang, and S. Si, "A novel small molecule which increases Osteoprotegerin expression and protects against ovariectomyrelated bone loss in rats," Frontiers in Pharmacology, Vol. 10, pp. 103, March 2019. DOI: 10.3389/fphar.2019.00103   DOI
74 S. O. Skouby, J. Gram, L. E. Andersen, J. Sidelmann, K. R. Petersen, and J. Jespersen, "Hormone replacement therapy: estrogen and progestin effects on plasma C-reactive protein concentrations," American journal of obstetrics and gynecology, Vol. 186, No. 5, pp. 969-977, May 2002. DOI: 10.1067/mob.2002.122414   DOI
75 A. N. A. Wadiah, F. K. Ooi, C. K. Chen, and W. D. W. Nudri, "Effects of chocolate malt drink consumption combined with aerobic dance exercise on blood bone metabolism markers, antioxidant enzymes and aerobic capacity in young females," Sport Exerc Med Open J, Vol. 1, No. 3, pp. 71-80, July 2015. DOI: 10.17140/SEMOJ-1-111   DOI
76 K. J. Friesen, R. Rozenek, K. Clippinger, K. Gunter, A. C. Russo, and S. E. Sklar, "Bone mineral density and body composition of collegiate modern dancers," Journal of Dance Medicine & Science, Vol. 15, No. 1, pp. 31-36, March 2011.
77 H. Y. Wu, T. H. Tsao, C. H. Hsu, J. H Tu, and C. B. Yang, "The effects of low-impact dance on knee torque and lower extremity mobility in middle-aged and older women," Journal of Nursing Research, Vol. 19, No. 4, pp. 267-274. December 2011. DOI: 10.1097/JNR.0b013e318236cfb2   DOI
78 N. Ahn, and K. Kim, "Effects of 12-week exercise training on osteocalcin, high-sensitivity C-reactive protein concentrations, and insulin resistance in elderly females with osteoporosis," Journal of physical therapy science, Vol. 28, No. 8, pp. 2227-2231, August 2016. DOI: 10.1589/jpts.28.2227   DOI
79 K. Akesson, P. H. Vergnaud, P. D. Delmas, and K. J. Obrant, "Serum osteocalcin increases during fracture healing in elderly women with hip fracture," Bone, Vol. 16, No. 4, pp. 427-430, April 1995.   DOI
80 E. A. Greco, A. Lenzi, and S. Migliaccio, "The obesity of bone" Therapeutic advances in endocrinology and metabolism, Vol. 6 No. 6, pp. 273-286, June 2011. DOI: 10.1177/2042018815611004.   DOI
81 C. J. Rosen, and A. Klibanski, "Bone, fat, and body composition: evolving concepts in the pathogenesis of osteoporosis," The American journal of medicine, Vol. 122, No. 5, pp. 409-414, May 2009. DOI: 10.1016/j.amjmed.2008.11.027   DOI
82 J. J. Cao, "Effects of obesity on bone metabolism," Journal of orthopaedic surgery and research, Vol. 6, No. 1, pp. 30, June 2011. https://link.springer.com/article/10.1186/1749-799X-6-30   DOI
83 J. E. Compston, J. Flahive, D. W. Hosmer, N. B. Watts, E. S. Siris, S. Silverman, ... and J. W. Nieves, "Relationship of weight, height, and body mass index with fracture risk at different sites in postmenopausal women: the Global Longitudinal study of Osteoporosis in Women (GLOW)," Journal of Bone and Mineral Research, Vol. 29, No. 2, pp. 487-493, February 2014. DOI: 10.1002/jbmr.2051   DOI
84 E. A. Greco, R. Fornari, F. Rossi, V. Santiemma, G. Prossomariti, C. Annoscia, ... and G. Spera, "Is obesity protective for osteoporosis? Evaluation of bone mineral density in individuals with high body mass index," International journal of clinical practice, Vol. 64, No. 6, pp. 817-820, May 2010. DOI: 10.1111/j.1742-1241.2009.02301.x   DOI