• Title/Summary/Keyword: OsGI

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Effect of Stent Placement on Survival in Patients with Malignant Portal Vein Stenosis: A Propensity Score-Matched Study

  • Dong Jae Shim;Jong Woo Kim;Doyoung Kim;Gi-Young Ko;Dong Il Gwon;Ji Hoon Shin;Yun-Jung Yang
    • Korean Journal of Radiology
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    • v.23 no.1
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    • pp.68-76
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    • 2022
  • Objective: Percutaneous portal vein (PV) stent placement can be an effective treatment for symptoms associated with portal hypertension. This study aimed to evaluate the effect of PV stenting on the overall survival (OS) in patients with malignant PV stenosis. Materials and Methods: Two groups of patients with malignant PV stenosis were compared in this retrospective study involving two institutions. A total of 197 patients who underwent PV stenting between November 2016 and August 2019 were established as the stent group, whereas 29 patients with PV stenosis who were treated conservatively between July 2013 and October 2016 constituted the no-stent group. OS was compared between the two groups before and after propensity score matching (PSM). Risk factors associated with OS were evaluated using the Cox proportional hazards model. Procedure-associated adverse events were also evaluated. Results: The stent group finally included 100 patients (median age, 65 [interquartile range, 58-71] years; 64 male). The no-stent group included 22 patients (69 [61-75] years, 13 male). Stent placement was successful in 95% of attempted cases, and the 1- and 2-year stent occlusion-free survival rate was 56% (95% confidence interval, 45%-69%) and 44% (32%-60%), respectively. The median stent occlusion-free survival time was 176 (interquartile range, 70-440) days. OS was significantly longer in the stent group than in the no-stent group (median 294 vs. 87 days, p < 0.001 before PSM, p = 0.011 after PSM). The 1- and 3-year OS rates before PSM were 40% and 11%, respectively, in the stent group. The 1-year OS rate after PSM was 32% and 5% in the stent and no-stent groups, respectively. Anemia requiring transfusion (n = 2) and acute thrombosis necessitating re-stenting (n = 1) occurred in three patients in the stent group within 1 week. Conclusion: Percutaneous placement of a PV stent may be effective in improving OS in patients with malignant PV stenosis.

The characteristics of fungal-mycelium-based composite materials using spent mushroom substrates of Flammulina velutipes (팽이버섯 수확후배지를 이용한 곰팡이 균사체 기반 복합소재의 특성)

  • Gi-Hong An;Du-Ho Choi;Jae-Gu Han;Kang-Hyo Lee
    • Journal of Mushroom
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    • v.21 no.3
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    • pp.185-189
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    • 2023
  • This study was conducted to develop a renewable and sustainable bio-material to replace polystyrene (EPS) in fungal-mycelium-based composite using agricultural by-products. Four mushrooms (Ganoderma lucidum, Fomitella fraxinea, Phellinus linteus, and Schizophyllum commune) were cultured in an oak sawdust plus rice bran substrate to select the mushroom with the best growth. The mycelia of G. lucidum showed the best growth. To investigate the optimal mixing ratio with spent mushroom substrate (SM) and oak sawdust (OS), samples were prepared by mixing SM and OS at ratios of 50%:50%, 60%:40%, and 80%:20% (w/w). Each substrate was then inoculated with G. lucidum. G. lucidum showed the best mycelial growth of 140.0 mm in the substrate with SM and OS mixed at a 60%:40% ratio. It was also found that the substrate with SM and OS mixed at a 60%:40% ratio had the best handling properties. The compressive strength of mycelial materials inoculated with G. lucidum was in the range of 300-302 kgf mm-1, and the materials were four times stronger than polystyrene materials. These results indicate that substrates comprising spent mushroom substrate mixed with oak sawdust can be successfully upcycled to mycelium-based composite materials using G. lucidum. This represents a sustainable approach.

스마트폰 신종 Phishing의 피해사례 및 대응방안 분석

  • Yang, Jun-Keun;Ha, Gi-Ung;Kim, Hak-Beom
    • Review of KIISC
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    • v.23 no.4
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    • pp.73-81
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    • 2013
  • 최근 정보통신기술 분야의 최대 관심사는 스마트폰 분야이다. 이러한 흐름에 발맞추어 스마트폰에 관련된 다양한 기술이 점진적으로 발달하였고, 누구나 쉽게 스마트폰을 이용하여 증권 거래 및 인터넷 검색, 인터넷 뱅킹 등의 다양한 서비스를 이용하고 있다. 이렇게 우리 생활에 점차 밀접한 관계를 맺음에 따라 그와 관련된 신종 Phishing들이 등장하게 되어 피해가 속출하고 있다. 본 논문에서는 스마트폰 신종 Phishing이 쉽게 발생할 수 있는 개방형 OS 환경의 특징과 스마트폰 환경에 새롭게 등장한 Smishing의 정의와 피해사례, 그리고 QRishing의 정의를 기술한다. 또한, 신종 Phishing의 피해사례와 그에 대한 대응방안에 대해 기술한다.

Implementation of a XHTML Browser for Palm PDA (Palm PDA 용 XHTML 브라우저 구현)

  • Cho, Gi-Sung;Cho, Seung-Ho;Cho, Bum-Joon
    • Proceedings of the Korea Information Processing Society Conference
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    • 2002.11b
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    • pp.1269-1272
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    • 2002
  • 현재 세계적인 이동통신 업체들은 대부분 XHTML Basic 을 수용하여 새로운 브라우저들은 WAP 프로토콜을 배제하고 TCP/IP 기반의 통신을 지원하는 경향을 나타내고 있다. 본 논문에서는 이러한 기술 추세를 반영하여 WAP 2.0 을 지원하는 PalmOS 용 XHTML 브라우저를 개발하였다. 본 브라우저의 특성은 이식성을 높이면서 휴대용 단말기의 자원 제약을 극복하기 위하여 이미지 변환 프락시를 활용하는 방식을 채택한 점이다.

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Development of an Open Sandwich Fluoroimmunoassay Based on FRET (FRET에 기반한 Open Sandwich Fluoroimmunoassay)

  • Wei, Quande;Lee, Moon-Kwon;Seong, Gi-Hun;Choo, Jae-Bum;Lee, Eun-Kyu
    • KSBB Journal
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    • v.22 no.6
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    • pp.426-432
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    • 2007
  • We have developed a sensitive, one-step, homogeneous open sandwich fluoroimmunoassay (OsFIA) based on fluorescence resonance energy transfer (FRET) and luminescent semiconductor quantum dots (QDs). In this FRET assay, estrogen receptor-$\beta$ (ER-$\beta$) antigen was incubated with QD-labeled anti-ER-$\beta$ monoclonal antibody and AF (Alexa Fluoro)-labeled anti-ER polyclonal antibody for 30 minutes, followed by FRET measurement. The dye separation distance was estimated to be between $80\sim90\;{\AA}$. The present method is rapid, simple and highly sensitive, and did not require the bound/free reagent separation steps and solid-phase carriers. A concentration as low as 0.05 nM (2.65 ng/ml) receptor was detected with linearity ($R^2$ > 0.990). In addition, the assay was performed with commercial antibodies. This assay provides a convenient alternative to conventional, laborious sandwich immunoassays.

Molecular Docking of Tetrahydrofuran-2-yl Analogues to Porcine Odorant Binding Proteins (pOBP & pPBP) and Binding Interactions (돼지 냄새물질 결합 단백질 (pOBP 및 pPBP)에 대한 Tetrahydrofuran-2-yl 유도체의 분자도킹과 결합 상호작용)

  • Cho, Yun-Gi;Park, Chang-Sik;Sung, Nack-Do
    • Reproductive and Developmental Biology
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    • v.34 no.1
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    • pp.7-13
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    • 2010
  • The binding affinity constants ($p(Od)_{50}$) and molecular docking scores (OS) between porcine odorant binding proteins pOBP (1HQP) and pPBP (1GM6) as receptor and a series of tetrahydrofuran-2-yl (A & B) analogues as substrate, and their interactions were discussed quantitatively using three-dimensional quantitative structure-activity relationship (30-QSAR) models. The statistical qualities of the optimized CoMF A models for pOBP were better than those of the CoMSIA models. The binding affinity constants and OS between substrate and receptor molecules were dependent upon steric and hydrophobic interaction. The DS constants of the substrates into the binding site of OBP (1HQP) were bigger than those of PBP (1GM6). The resulting contour maps produced by the optimized CoMFA model were used to identify the structural features relevant to the binding affinity in binding site of pOBP.

Implementation of temperature measurement system using Arduino and Android OS (아두이노와 안드로이드 OS를 이용한 온도측정 시스템 구현)

  • Kim, Sung Jin;Jeon, Seong;Choi, Jin Myung;Park, Jong Chan;Oh, Gi Hwan;Kim, Da Eun;Kim, Eun Seo
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2022.07a
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    • pp.281-284
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    • 2022
  • 코로나로 인해 대한민국의 모든 산업은 위축되었고, 모두가 힘든 시기를 보내고 있지만 그 중 캠핑산업은 예외이다. 코로나와 상관없이 야외에서 즐길 수 있는 캠핑장을 찾는 사람들은 꾸준히 늘어나고 있다. 이러한 캠핑에 있어서 가장 중요한 요소는 먹거리이다. 그 중 가장 대표적이고 잘 알려진 먹거리는 고기 요리이다. 본 논문은 캠핑족들의 편의를 제공해주기 위해 블루투스 통신을 통해 적정 고기 온도를 알려주는 서비스를 제공한다. 아두이노와 블루투스 서미스터 센서를 연결하여 안드로이드 스튜디오를 활용하여 애플리케이션을 개발하고, 블루투스로 통신을 통해 외부 장치 데이터 통신 구현을 통하여 실시간 온도 데이터를 확인할 수 있다. 또한 Firebase를 활용하여 레시피북을 제작해 접하지 못했던 육류 위주의 레시피를 제공하는 서비스도 제공한다.

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Report of 5 Clinical Cases of Visiting Korean Medicine Care for Community in 2020 (2020년 지역사회 한의학 방문돌봄사업 5례 임상증례 보고)

  • Dae Sung Jung;Jae Ryong Bae;Jae Heung Lee
    • Journal of Korean Medical Ki-Gong Academy
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    • v.21 no.1
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    • pp.22-42
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    • 2022
  • Objective : The researcher participated in the visiting treatment project organized by OO City in 2020 and showed the advantages of visiting Korean Medicine, so I would like to report it. Methods : A comprehensive Korean Medicine intervention method was performed for each symptom, and changes in basic physical strength were observed through vital signs, NRS, Single Leg Stance (SLS), and Chair Stand Test (CST) tests. Results : It can be seen that the NRS level, a pain scale for chronic pain, generally decreased at the last treatment compared to the beginning of treatment. Satisfaction with Project Information (PI) was relatively low at 3.20±1.30, but Ease of Participation (EoP), Intention to Participate Again (IPA), Expansion of Project (ExP), and Overall Satisfaction (OS) were high at 5.00±0.00. Conclusions : Summarizing the advantages of visiting Korean Medicine is that the treatment satisfaction for chronic pain is high, the patient's satisfaction is high, the treatment tool is easy to carry, and various visiting treatment services can be implemented.

Temozolomide Salvage Chemotherapy for Recurrent Anaplastic Oligodendroglioma and Oligo-Astrocytoma

  • Gwak, Ho-Shin;Yee, Gi Taek;Park, Chul-Kee;Kim, Jin Wook;Hong, Yong-Kil;Kang, Seok-Gu;Kim, Jeong Hoon;Seol, Ho Jun;Jung, Tae-Young;Chang, Jong Hee;Yoo, Heon;Hwang, Jeong-Hyun;Kim, Se-Hyuk;Park, Bong Jin;Hwang, Sun-Chul;Kim, Min Su;Kim, Seon-Hwan;Kim, Eun-Young;Kim, Ealmaan;Kim, Hae Yu;Ko, Young-Cho;Yun, Hwan Jung;Youn, Ji Hye;Kim, Juyoung;Lee, Byeongil;Lee, Seung Hoon
    • Journal of Korean Neurosurgical Society
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    • v.54 no.6
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    • pp.489-495
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    • 2013
  • Objective : To evaluate the efficacy of temozolomide (TMZ) chemotherapy for recurrent anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA). Methods : A multi-center retrospective trial enrolled seventy-two patients with histologically proven AO/AOA who underwent TMZ chemotherapy for their recurrent tumors from 2006 to 2010. TMZ was administered orally (150 to 200 $mg/m^2/day$) for 5 days per 28 days until unacceptable toxicity occurred or tumor progression was observed. Results : TMZ chemotherapy cycles administered was median 5.3 (range, 1-41). The objective response rate was 24% including 8 cases (11%) of complete response and another 23 patients (32%) were remained as stable disease. Severe side effects (${\geq}$grade 3) occurred only in 9 patients (13%). Progression-free survival (PFS) of all patients was a median 8.0 months (95% confidence interval, 6.0-10.0). The time to recurrence of a year or after was a favorable prognostic factor for PFS (p<0.05). Overall survival (OS) was apparently differed by the patient's histology, as AOA patients survived a median OS of 18.0 months while AO patients did not reach median OS at median follow-up of 11.5 months (range 2.7-65 months). Good performance status of Eastern Cooperative Oncology Group 0 and 1 showed prolonged OS (p<0.01). Conclusion : For recurrent AO/AOA after surgery followed by radiation therapy, TMZ could be recommended as a salvage therapy at the estimated efficacy equal to procarbazine, lomustine, and vincristine (PCV) chemotherapy at first relapse. For patients previously treated with PCV, TMZ is a favorable therapeutic option as 2nd line salvage chemotherapy with an acceptable toxicity rate.