• 제목/요약/키워드: Origins

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1H NMR-based metabolomic study of Cornus officinalis from different geographical origin

  • Jung, Young-Ae;Jung, Young-Sang;Hwang, Geum-Sook
    • Journal of the Korean Magnetic Resonance Society
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    • v.15 no.2
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    • pp.90-103
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    • 2011
  • Cornus officinalis (Cornaceae) is primarily grown in Asian countries. The pericarp of C. officinalis (Corni Fructus) is a well-known traditional medicine with tonic, analgesic, and diuretic properties. We analyzed methanolic extracts of Corni Fructus (grown in Korea and China) by $^1H$ NMR spectroscopy. Metabolite profiling was performed to characterize the metabolic difference between different Corni Fructus origins (Korea or China). Principal components analysis revealed significant separation between Comus Fructus from different origins. The metabolites responsible for differences were identified using loading plots, coefficients plots, and variable influence on projection followed by t-tests. As a result, 16 metabolites were identified and quantified; tyrosine, acetate, sucrose, and malate differed the most between origins. These data suggest that NMR-based metabolomics can be used to identify differences between Corni Fructus samples obtained from different regions.

Termination Sites of fleplication Are Anchored to the Nuclear Matrix during S Phase in Mouse LPI-1 Cells (생쥐 LP1-1 세포에서 S phase 동안 nuclear matrix에 고정되어 있는 복제 끝점)

  • 이형호;이갑열
    • The Korean Journal of Zoology
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    • v.37 no.3
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    • pp.318-323
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    • 1994
  • The association of replication origins/termini with nuclear matrix during S phase was investigated by DNase digestion of halo structures in synchronized mouse LPI-1 cells. The binding of parental DNA to nuclear matrix was constant throughout S phase. When nuclear matrix was isolated from the cells pulse-labeled with 3H-thvmidine at various stases of S phase, total 3H-labels associated with nuclear matrix were specifically higher at So, Sa and Ss stages than other stases of S phase, suggesting that the newly synthesized DNAs at those stages are not excluded out of nuclear matrix. Similar patterns were obsenred from the pulse-chase experiments, in which cells were pulse-labeled at each stage of S phase and further incubated for 1 hr. These results suggest that the replication origins and termini are fixed at the nuclear matrix, and that the nuclear matrix binding fractions of DNA at 3C-pause may contain a large population of replication origins and termination sites.

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Metabolic Discrimination of Safflower Petals of Various Origins Using 1H NMR Spectroscopy and Multivariate Statistical Analysis

  • Whang, Wan-Kyun;Lee, Min-Won;Choi, Hyung-Kyoon
    • Bulletin of the Korean Chemical Society
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    • v.28 no.4
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    • pp.557-560
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    • 2007
  • The metabolic discrimination of safflowers from various geographical origins was performed using 1H nuclear magnetic resonance (NMR) spectroscopy followed by principal components analysis. With a combination of these techniques, safflower samples from different origins could be discriminated using the first two principal components (PC) of the 1H NMR spectra of the 50% methanol fractions. PC1 and PC2 accounted cumulatively for 91.3% of the variation in all variables. The major peaks in the 1H NMR spectra that contributed to the discrimination were assigned to fatty acid (terminal CH3), lactic acid, acetic acid, choline derivatives, glycine, and safflower yellow derivatives. In this study, we suggest that various types of safflower can be discriminated using PCA and 1H NMR spectra.

Dynamic Behavior Analysis of an Eccentric Rotor with Unbalanced Magnetic Forces in BLDC Motors (BLDC 전동기의 전자기적 불평형력을 고려한 편심 회전자의 동적 거동 해석)

  • Kim, Tae-Jong;Hwang, Sang-Mun;Park, No-Gil
    • The Transactions of the Korean Institute of Electrical Engineers B
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    • v.48 no.11
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    • pp.604-610
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    • 1999
  • Vibration of a rotor-bearing system driven by an electric motor is a coupled phenomenon between mechanical characteristics and magnetic origins through the air-gap. With the advent of new high-energy magnets together with high precision motor applications, magnetic sources of vibration are becoming more serious. This paper investigates the transient whirl responses of a rotor system with purely mechanical origins and compares it with that of magnetically coupled origins. A perturbation method is applied to model the magnetic field associated with rotor eccentricity. Electromagnetic forces are obtained by the Maxwell stress method, which utilizes the analytical expression of radial flux density distribution. The FEM was applied to a rotor-motor system to illustrate magnetically coupled effects in rotor dynamics. Results show that magnetically coupled sources significantly affect the vibration of the rotor-motor system.

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Domestic Research Trends on Fluorescent Dissolved Organic Matter in Marine Environment (해양 환경의 형광용존유기물에 관한 국내 연구 동향)

  • Kim, Jeonghyun
    • Ocean and Polar Research
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    • v.43 no.4
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    • pp.353-363
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    • 2021
  • Fluorescent dissolved organic matter (FDOM) is referred to organic matter which absorbs efficiently solar radiation energy and fluorescence in the water column. The component and molecular structure of marine organic matter can be changed depending on the various substances and origins of organic matter, and then the organic matter has unique fluorescent properties. As the cutting-edge analytical techniques of optical measurement continuously developing from last few decades, a study on FDOM has been applied as a biogeochemical tracer to quantify the organic matter concentration and to investigate the behaviors and origins of organic matter. Especially, the marine environment around the Korean Peninsula is an ideal research area to study FDOM because of various oceanographic characteristics and the origins of organic matter. This study describes the general properties of FDOM and introduces the cycling and behaviors of marine organic matter based on the domestic research studies.

Common pitfall of plastic surgeon for diagnosing cutaneous odontogenic sinus

  • Chang, Lan Sook
    • Archives of Craniofacial Surgery
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    • v.19 no.4
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    • pp.291-295
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    • 2018
  • Dental origins are a common cause of facial cutaneous sinus tracts. However, it can be easily overlooked or misdiagnosed if not suspected by a surgeon who is not familiar with dental origins. Cutaneous odontogenic sinuses are typically nodulocystic lesions with discharge and are most frequently located on the chin or jaw. This article presents two cases of unusual cutaneous odontogenic sinus presentations, as deep dimpling at the middle of the cheek. The patients were undergone surgical excision of sinus tract and dimpling immediate before and after treatment of causal teeth and the lesions resolved without recurrence. Surgeons should consider dental origins of facial dimpling lesions with discharge and provide appropriate treatment.

Star-Gas Misalignment in Galaxies: II. Origins Found from the Horizon-AGN Simulation

  • Khim, Donghyeon J.;Yi, Sukyoung K.
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.1
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    • pp.29.1-29.1
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    • 2021
  • There have been many studies aiming to reveal the origins of the star-gas misalignment found in galaxies, but there still is a lack of understanding of the contribution from each formation channel candidate. We explore the properties, origins, and lifetimes of the star-gas misalignment using Horizon-AGN, a large-volume cosmological simulation. First, the misalignment fraction shows a strong anti-correlation with the kinematic morphology (V/sigma) and the cold gas fraction of the galaxy. This result is consistent with the result of integral field spectroscopy observations. Second, we have identified four main formation channels of misalignment and quantified their level of contribution: mergers (35%), interaction with nearby galaxies (23%), interaction with dense environments or their central galaxies (21%), and secular evolution including smooth accretion from neighboring filaments (21%). Third, the decay timescale of the misalignment is strongly linked with the kinematic morphology of the galaxy: early-type galaxies (2.28 Gyr) tend to have a longer misalignment lifetime than LTGs (0.49 Gyr). We also found that the morphology and cold gas fraction are both and independently anti-correlated with the misalignment lifetime.

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Discrimination of Cultivars and Cultivation Origins from the Sepals of Dry Persimmon Using FT-IR Spectroscopy Combined with Multivariate Analysis (FT-IR 스펙트럼 데이터의 다변량 통계분석을 이용한 곶감의 원산지 및 품종 식별)

  • Hur, Suel Hye;Kim, Suk Weon;Min, Byung Whan
    • Korean Journal of Food Science and Technology
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    • v.47 no.1
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    • pp.20-26
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    • 2015
  • This study aimed to establish a rapid system for discriminating the cultivation origins and cultivars of dry persimmons, using metabolite fingerprinting by Fourier transform infrared (FT-IR) spectroscopy combined with multivariate analysis. Whole-cell extracts from the sepals of four Korean cultivars and two different Chinese dry persimmons were subjected to FT-IR spectroscopy. Principle component analysis (PCA) and partial least squares discriminant analysis (PLS-DA) of the FT-IR spectral data successfully discriminated six dry persimmons into two groups depending on their cultivation origins. Principal component loading values showed that the 1750-1420 and $1190-950cm^{-1}$ regions of the FT-IR spectra were significantly important for the discrimination of cultivation origins. The accuracy of prediction of the cultivation origins and cultivars by PLS regression was 100% (p<0.01) and 85.9% (p<0.05), respectively. These results clearly show that metabolic fingerprinting of FT-IR spectra can be applied for rapid discrimination of the cultivation origins and cultivars of commercial dry persimmons.

Review on Original Plane of Oriental Medicines Used in Korea (국내 유통 한약재의 기원식물에 관한 고찰)

  • 김관수;김호철
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.48
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    • pp.79-95
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    • 2003
  • To clarify the botanical origins of oriental medicines which have been argued or confused for plant origins, species of original plants were investigated through the textural research for oriental medicines and the comparison of Chinese, Korean, Japanese and North Korean Pharmacopoeia. Twenty oriental medicines were studied; Angelicae Gigantis Radix, Rhei Rhizoma, Atractylodis Rhizoma Alba, Aconiti Lateralis Radix Preparata, Acanthopanacis Cortex, Osterici Radix, Cnidii Rhizoma, Saposhnikovae Radix, Magnoliae Cortex, Paeoniae Radix, Liriopis Tuber, Zanthoxyli Fructus, Achyranthis Radix, Sinomeni Caulis et Rhizoma, Polygonati Rhizoma, Cinnamomi Cortex, Visci Herba et Loranthi Ramulus, Fritillariae Thunbergii Bulbus, Pogostemonis Herba, and Curcumae Longae Radix.

The Origins of Fall Incidents in Construction Sites Classified by Locations and Trades of Concern (건설공사 추락재해의 발생장소별.피재자별 분석)

  • 이규진
    • Journal of the Korean Society of Safety
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    • v.16 no.2
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    • pp.85-90
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    • 2001
  • In construction industries, the problem areas in safety are different to those of manufacturing. For instance, construction safety efforts must strongly emphasize fall prevention, whereas caught-in/ between incidents and electrical shocks are common in manufacturing. This paper reports an analysis of fall incidents that lead to fatalities in 1999 and in 2000. It also provides a safety plan for fall prevention by analyzing the origins of fall incidents by their trades and locations of concern. The findings of this study are expected to contribute toward reducing fall incidents in construction industry.

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