• Bulletin of the Korean Chemical Society
• /
• v.33 no.11
• /
• pp.3565-3570
• /
• 2012

Until now, few groups reported the antifreeze activity of cyclic glycopeptides; however, the tedious synthetic procedure is not amenable to study the intensive structure activity relationship. A series of N-linked cyclic glycopeptoids and glycopeptide have been prepared to evaluate antifreeze activity as a function of peptide backbone cyclization and methyl stereochemical effect on the rigid Thr position. This study has combined the cyclization protocol with solid phase peptide synthesis and obtained significant quantities of homogeneous cyclic glycopeptide and glycopeptoids. Analysis of antifreeze activity revealed that our cyclic peptide demonstrated RI activity while cyclic glycopeptoids showed no RI activity. These results suggest that the subtle changes in conformation and Thr orientation dramatically influence RI activity of N-linked glycopeptoids.

• Korean Journal of Social Welfare
• /
• v.44
• /
• pp.346-374
• /
• 2001

The purpose of this study is to investigate the relationship between suicidal ideation among Korean adolescents and factors such as family conflict, cohesion, organization of family activities, expressiveness, independence, achievement orientation, depression, stress, and support of friends and teachers, according to the individual student's parental type. The study sample consisted of 1908 high school students in the 11th grade from the city of Inchon. The results showed that in both males and females, suicidal ideation was greater in students from single-parent families than two natural-parent families and greater in step-parent families than in single-parent families. As an exploratory study, the analysis of factors influencing suicidal ideation according to parental type showed that the study model accounted for 33.6% for students from two natural-parent families, 42.8% for students from single-parent families and 84.5% for students from step-parent families, of the variance in suicidal ideation. This indicates that the study model is more appropriate for application to students from single-parent and step-parent families. In addition, the study shows that the factors of influence and the way these factors make an influence tended to differ according to parental type. This indicates that in terms of predicting suicidal ideation, it is more effective to study students according to parental type than as a whole. It also indicates that it is ineffective to take the same approach in dealing with suicidal ideation for students with different parental types.

• Bulletin of the Korean Chemical Society
• /
• v.26 no.6
• /
• pp.952-958
• /
• 2005

Angiotensin-converting enzyme (ACE) is known to be primarily responsible for hypertension. Threedimensional quantitative structure-activity relationship (3D-QSAR) models have been constructed using the comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) for a series of 28 ACE inhibitors. The availability of ACE crystal structure (1UZF) provided the plausible biological orientation of inhibitors to ACE active site (C-domain). Alignment for CoMFA obtained by docking ligands to 1UZF protein using FlexX program showed better statistical model as compared to superposition of corresponding atoms. The statistical parameters indicate reasonable models for both CoMFA ($q^2$ = 0.530, $r^2$ = 0.998) and CoMSIA ($q^2$ = 0.518, $r^2$ = 0.990). The 3D-QSAR analyses provide valuable information for the design of ACE inhibitors with potent activity towards C-domain of ACE. The group substitutions involving the phenyl ring and carbon chain at the propionyl and sulfonyl moieties of captopril are essential for better activity against ACE.

• The korean journal of orthodontics
• /
• v.18 no.1 s.25
• /
• pp.65-78
• /
• 1988

The development of good arch form, the orientation of the dentition with relation to the craniofacial skeleton and the establishment of correct relationship of axial inclination of upper and lower teeth are required in normal occlusion, but different teeth present different degrees of axial inclination. The purpose of this study was to investigate the axial inclination of upper and lower teeth by analyzing $45^{\circ}$ oblique and $90^{\circ}$ cephalometric roentgenograms of 35 Korean males and 34 females with normal occlusion. The obtained results were as follows: 1. Mean and standard deviation of mesiodistal axial inclination of upper and lower teeth related to palatal plane and occlusal plane were obtained. 2. Mesiodistal axial inclination of upper first premolar was nearly perpendicular to palatal plane, and the axis of lower first premolar was nearly perpendicular to occlusal plane. 3. There was no difference in the mesiodistal axial inclination of anteriorly positioned teeth between the three groups: third molar eruption into good alignment (Group 1), third molar impaction or partial eruption (Group 2), third molar agenesis (Group 3). 4. There were low correlationships only between the axial inclination of central incisor and the mesiodistal axial inclination of canine and first premolar, but no correlationships between central incisor and posterior teeth behind first premolar.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.26 no.6
• /
• pp.611-616
• /
• 2008

When extracting geo-referenced 3D data from cameras mounted on Mobile Mapping Systems, one of important properties for accuracy of extracted data is the alignment of the relative translation(lever-arm) and rotation(bore-sight) between the coordinate systems of Inertial Measurement Unit(IMU)/Ground Positioning System(GPS) and cameras. Since the conventional method calculates absolute camera orientation using ground control points (GCP), the alignment is determined in one Coordinated System (GPS Coordinated System). It basically require GCP. We proposed a mathematical model for the alignment using the initially uncoupled data of cameras and IMU/GPS without GCPs.

• Human Ecology Research
• /
• v.56 no.3
• /
• pp.301-315
• /
• 2018

This study explores the critical reflection process experienced by home economics preservice teachers during practicum. Data were collected in a critical analysis of class, practicum review, and journals written by sixteen preservice teachers. Text material were composed of 188 transcripts on A4 paper and 36 page of mini-notes. The collected data were analyzed by a thematic coding method in qualitative research and proceeded in the order of three steps of transference, coding, and subject discovery. The emerging themes were: 1) Observing class 2) Practicing class 3) Growth of class practice 4) Reflecting class. First, the observing class was an exploration process through the viewing of daily classes that involved the process of recognizing the classroom situation and various classroom contexts. Second, the practicing class was to strengthen the consideration of the class to form a relationship that could lead to learning in educational situations. Third, the growth of class practice was intended to recognize the orientation of the subject matter with pedagogical content knowledge. Four, the reflecting class was the process of experiencing practice with a continuous understanding of the class, class reflection, and changing the perspective from the current status. There is a part where critical reflection is difficult to be promoted deeply during 4 weeks; however, there was a possibility of a reflection practice that could promote achievement through the experience of a practicing class.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2001.11a
• /
• pp.463-466
• /
• 2001

In recent year, Ferroelectric BLT($Bi_{4-x}$La$_{x}$Ti$_3$O$_{12}$) is a promising candidate materials. This study was Practiced to make good conditions of BLT targets. In this study, calcination and sintering temperature were kept at 75$0^{\circ}C$, 110$0^{\circ}C$ for 2 hour respectively. the density obtained 7.612, 7.98, 7.877 g/㎤ as La$_2$O$_3$ contents were 0.0mol%, 0.25mo1%, 0.5mol%. Especially, the lanthanum content of 0.5 mol% measured C-axis (117) preferred orientation more than the others targets in the XRD. In $\varepsilon$$_{r}$-f relationship using by HP 4194 A impedance analyzer, the 0.5 mol% observed above 200 relative dielectric constant. but the dissipation factor was higher than others targets at 100Hz~13MHz range. SEM photograph with the content of La$_2$O$_3$ was observed like rod and plate types.types.s.

• 연구논문집
• /
• s.31
• /
• pp.113-125
• /
• 2001

Silicon addition in titanium alloys generally results in solid solution hardening by silicon itself and precipitation hardening by titanium silicides. The morphology and distribution of the titanium silicides depend upon the alloy chemistry or the heat treatment condition, and play an important role in improving the mechanical properties of the alloys. In this study, the morphology and crystallographic characteristics of the titanium silicides in the Ti-Fe-Si alloy system were studied. Three types of silicides were found in the alloys; (1) interconnected chain-like silicides at grain boundary, (2) coarse silicides over im, (3) fine silicides smaller than 0.2m. Ti3Si was dominant in cast + HIP condition while Ti5Si3 was dominant in as-cast state. It is recognized that $Ti_5Si_3$$\rightarrow$$Ti_3Si$ transition occurred by the peritectoid reaction and it may be promoted by the pressure during HIP. However, in the case of the fine silicides, $Ti_3Si$ and $Ti_5Si_3$ were found simultaneously even after HIP. Such a fine silicide was found to have a crystallographic orientation relationship with matrix.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.8 no.3
• /
• pp.727-732
• /
• 2004

In this paper, we introduce a new approach for real-time 3D face pose discrimination based on active IR illumination from a monocular view of the camera. Under the IR illumination, the pupils appear bright. We develop algorithms for efficient and robust detection and tracking pupils in real time. Based on the geometric distortions of pupils under different face orientations, an eigen eye feature space is built based on training data that captures the relationship between 3D face orientation and the geometric features of the pupils. The 3D face pose for an input query image is subsequently classified using the eigen eye feature space. From the experiment, we obtained the range of results of discrimination from the subjects which close to the camera are from 94,67％, minimum from 100％, maximum.

• Transactions on Electrical and Electronic Materials
• /
• v.13 no.1
• /
• pp.19-22
• /
• 2012

Transformation behavior of rapidly solidified Ti-47.3Ni (at%) alloy ribbons and thermal stability of the R phase in the ribbons were investigated by means of differential scanning calorimetry (DSC), X-ray diffraction, and transmission electron microscopy. Rapidly solidified Ti-47.3Ni alloy ribbons showed the two-stage B2-R-B19' martensitic transformation behavior. The B2-R transformation in the ribbons was observed even after annealing at 1,223 K, which was attributed to the fact that a specific orientation relationship between $Ti_2Ni$ and matrix in the ribbons is maintained after annealing at 1,223 K. The DSC peak temperature of the B2-R transformation ($T_R^*$) decreased with raising annealing temperature, which was attributed to the increased volume fraction of $Ti_2Ni$, thus causing an increased Ni content in the matrix.