• Journal of muscle and joint health
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• v.4 no.1
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• pp.26-47
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• 1997

The purpose of this study is to explore the treatment pattern of treatment of patients with arthritis. The grounded theory approach methodology was used in this study. The purposive sampling was conducted. 16 subjects who experienced RA, lived in middle sized city in Korea, and all women The results of this study were as follows : 1. The process of treatment was composed of the stage of symptom experience and the stage of sick role experience. The naming of the symptom was conducted in the stage of symptom experience through, the doctor shopping. The sick role experience was patterned by the choice of the treatment mode. 2. The treatment modes were roughly devided by western medicine and oriental or ethnic medicine. Several factors which affected the choice of the treatment mode were patient's economic state, educational level, religion, the acknowledgement of the cause of illness, duration of illness, lay referral system, the relationship of medical staff, and the acculturation of medical professionalism. The key component of the decision of the treatment was the level of the acculturation of medical professionalism. To enhance the acculturation of medical professionalism, we have to provide the information of cause and the prognosis of the disease to the patients and the variety of communication channel between medical staff and patients, and we should understand the medical culture according to the ages, gender, locations in Korea.

• The Journal of the Convergence on Culture Technology
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• v.7 no.1
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• pp.31-36
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• 2021

Stress is a common risk factor for health and is associated with the endocrine gland and immune system. Studies on the association between stress and biochemical factors have been conducted worldwide, but studies on the association have been rare in South Korea. Therefore, the aims of this study are to analyze the relationship of stress with demographic information and biochemical factors for domestic adults and derive risk factors for stress. For data analysis, stress and normal groups were analyzed using binary logistic regression. In both men and women, age and average daily sleep time during the weekday were highly associated with stress, and the depression score (Patient Health Questionnaire-9) was also highly related with stress. In women, white blood cell levels were highly associated with stress, and in men, red blood cell levels were highly related with stress. These findings will contribute to the prevention of stress and the national health in the future.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.167-169
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• 2021

There are only 14 public medical facilities available to residents regularly in the island area of Chungcheongnam-do, one health life support center, and one hospital ship, and these facilities and equipment cannot effectively respond to emergency patients such as severe trauma, cerebrovascular and cardiovascular diseases. The fastest means of transporting emergency patients is to use a doctor helicopter deployed at Dankook University Hospital (based in Cheonan). However, there is only one doctor helicopter deployed, and it cannot operate at night, and since it is in charge of all areas of Chungcheongnam-do, there is a limit to rapid transport in the event of a large number of patients. Therefore, we would like to review the necessity of "Chungnam-type Doctor UAM Development" to compensate for the problems of the urban aviation mobility (UAM) industry and the emergency patient transport system in islands, a field of the 4th industry.

• The KIPS Transactions:PartB
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• v.18B no.6
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• pp.389-396
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• 2011

There is getting worse to various liver diseases due to change in eating habits, stress, alcohol etc in modern society. Therefore, we proposed methodology to diagnose early for liver disease to study the influence on voice in liver diseases. To this end, we carried out experiment to apply parameter of voice analysis to collect each voice inpatients and patients by treatment of liver diseases patients. Particularly, we carried out experiment to apply element value of pronunciation and the third formant frequency bandwidths about velar sounds associated liver in oriental medicine, then to produce objective index resonance cavity and influence vocalization in liver diseases. In addition, we carried out to study about design of system to monitoring a liver function in u-Health environment based on result by experiment.

• Journal of Acupuncture Research
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• v.22 no.3
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• pp.37-51
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• 2005

Mast cell is a cell that functions mainly in our body with a respect to inflammation and allergic response. Bee venom has been progressed in a study as a model related to mechanism in alleviation of pain until now, but it is being progressed in a study relevant to immunocyte in anti-inflammation or anti-allergic response. The present study is aimed to present the basis related to a future study of gene, by researching the influence of melittin and MCD Peptide, which are major ingredients in Bee venom, upon the expression of gene in the mast cell strain. In this study, it dealt with melittin and MCD Peptide respectively, in the effective concentration after passing though the experiment of cytotoxicity by using human mast cell strain. Also, with the respect in the aspect of expression in gene that changes at this time, information was obtained through the technique of analyzing microarray. Through experimental statistics, when regarding a case that global M is significant in more than 1 or -1, in melittin, all 7 genes were accelerated, and 8 inhibited. In MCDP, 7 genes were accelerated and 17 genes inhibited. The function in the body to which these genes are related, was associated with the protein binding within a cell, the activation in the function of lymphocyte, the acceptor related to macrophage antigen. In cell nucleus, substance related to GABA A receptor, protein associated with cAMP reactive element, substance related to complement system No.8 and to B-cell, protein substance related to polycystic kidney disease, substance related to inflammation, and the protein substance of influencing coagulation of blood. Through these results of analysis, it could obtain more useful materials in clarifying the mechanism of action in melittin and MCD peptide, which are in charge of mainly medical action in the abdomen. Also, it is thought that an in-depth study on the influence of main ingredients in Bee venom, the wholly honey bee venom aqua upon anti-allergic response or anti-inflammation are further required.

• Korean Journal of Acupuncture
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• v.33 no.2
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• pp.67-74
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• 2016

Objectives : The Knee degenerative osteoarthritis patients are not satisfied with the conventional therapies of KDOA, which results in the use of alternative therapies. The miniscalpel acupuncture is effective in treating chronic soft tissue, releasing contractures. However, there is little scientific evidence supporting the use of miniscalpel acupuncture in knee degenerative osteoarthritis. This study was designed to obtain basic data for a further large-scale trial as well as provide information about the feasibility of miniscalpel acupuncture in knee degenerative osteoarthritis patients. Methods : We describe the protocol for a randomized controlled pilot clinical trial of 5 weeks duration. Twenty patients will be recruited and randomly allocated to two treatment groups: miniscalpel acupuncture treatment(experimental group); and acupuncture and electro-acupuncture treatment(control group). Miniscalpel acupuncture will be performed once with a 1-week interval for 3 weeks. Electro-acupuncture will be administered twice per week for a period of 3 weeks. The primary outcomes will be measured by visual analogue scale and range of motion. The secondary outcomes will be short-form McGill Pain Questionnaire and Western Ontario and McMaster Universities Osteoarthritis Index. Both primary and secondary outcomes will be measured at baseline and at 1, 2, 3 and 5 weeks(i.e. 2 weeks after treatment completion). Conclusions : This pilot study will provide a basic foundation for a future large-scale trial as well as information about the feasibility of miniscalpel acupuncture in knee degenerative osteoarthritis.

• Journal of the Institute of Electronics and Information Engineers
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• v.54 no.7
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• pp.115-124
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• 2017

The objective of study was to investigate the optimal echo phase for mouse brain enhancement scan using fast low angle shot (FLASH) sequence of 9.4T magnetic resonance imaging (MRI). For quantification based on this method, an MR phantom experiment and clinical research were done. The phantom experiment was conducted by fabricating three phantoms with different molar concentration of gadolinium to create changes in echo phase of 9.4T FLASH sequence used in mouse brain scans. In the phantom experiment, SSI was 25~27 [arbitrary units, a.u.] in each of 33 phases from $6{\pi}$ to $28{\pi}$, while RSP was 30~100 mmol. MPSI was 47~52 [a.u], while MPP, where MPSI is seen, was 0.8~9 mmol. EPMS was 80.8~108.0%, while ASIMP was formed between 21.1 and 31.8 [a.u]. In the clinical research, Finally, the occurrence rate of artifact that expressed -1 nd +1. The present study was able to quantify the degree of enhancement at FLASH sequence of 9.4T MRI, as well as identify the optimal echo phase during mouse brain enhancement scan.

• The KIPS Transactions:PartB
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• v.14B no.7
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• pp.503-512
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• 2007

An infant of a baby child who haven't communication skills through a language expresses their intention or baby condition as generally crying. Among these things, it is important to show a baby condition because their disease miss diagnosis time or remain to decide an exact diagnosis result too hard. For this, in this paper, we are going to develop system which decides where to be not good body point by analysing their face color and crying sound. Specifically, in this paper, we are going to act for baby heart diseases by doing feature extraction for their face region color and crying sound. To embody, we are going to present diagnosis method and compare analyze their crying sound a stand child, a different diseases child and a baby heart diseases child through each analyzed element. And also, we are going to extract matters to be attended to baby heart diseases through experiment and prepare objective index and an accuracy of baby heart diseases diagnosis result.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2019.05a
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• pp.533-536
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• 2019

Recombinant baculoviruses are widely used to express heterologous genes in cultured insect cells. Recombinant baculoviruses can serve as gene-transfer vectors for expression of recombinant proteins in a wide range of mammalian cell types. Baculovirus system has significant benefits in view of safety, large-scale, and high level of gene expression. In this study, baculoviral vectors which were reconstructed from pOPINEneo-3C-GFP vector, were recombined with cytomegalovirus (CMV) promoter, green fluorescent protein (GFP), and p53 with NcoI and XhoI. These recombinant vectors were infected with various cells and cell lines. The baculovirus vector thus developed was analyzed by comparing the metastasis and expression of the recombinant genes with conventional vectors. These results suggest that the baculovirus vector has higher efficiency in metastasis and expression than the control vector. This work was supported by a grant from Mid-Career Researcher Program(NRF-2016R1A2B4016552) through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT & Future Planning(MSIP).

• Journal of the Korea Institute of Information and Communication Engineering
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• v.5 no.1
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• pp.89-101
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• 2001

The conventional pattern-methods for discrimination of acupoint, meridian line which is the basic object of diagnosis and medical treatment in oriental medicine is discriminated the conduction point by the stimulation in body skin with DC. But, it is not sufficient to truth in discrimination ratio, coincident ratio, body effect, reproductivity. Therefore, this paper is extracting the optimal parameter of frequency and waveform in order to improve the conventional pattern, and proposing the SPAC(Single Power Alternative Current) stimulus pattern applying that. Also, this algorithm proposes to be able to discriminate with low pressure of the electrode by displaying in the level meter both the absolution and relation value of the skin current. It is able to decrease pain and body effect by electrode pressure and discriminate acupoint regardless of skin current in difficult discrimination spot. It is compared the performance of system applying the extracted optimal parameter and algorithm, and it is confirmed that there is difference in discrimination parameter of acupoint reacted to the individual and the meridian. It is compared that discrimination, coincident ratio of the traditional acupoints as the acupoint stimulation pattern. It is confirmed truth of optimal parameter and discrimination algorithm. Keyword: Meridian, Discrimination, Coincident, Body effect, Reproductivity, SPAC, Optimal parameter.