• 한국한의학연구원논문집
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• 제12권3호통권18호
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• pp.101-115
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• 2006

The purpose of this study was to introduce the differential standard of the types of Angelicae Pubescentis Radix. We established the classificatory standard according to the external and internal morphology and the physicochemistrical pattern for the four types of Aucklandiae Radix. The results follow: 1. At the external shape, Angelica pubescens f. biserrata has rising lenticel and dark brown surface, Its section is light gray and its xylem is yellow gray. Aralia continentalis has big stem mark in upper portion, its section has no dense tissue with yellow gray. Heracleum hemsleyanum has dark brown surface and little lenticel, its cortical layer is white yellow and xylem is isabella and powdered. 2. At the internal shape, Angelica pubescens f. biserrata has phloem with half of the root and rare vessel. Aralia continentalis has phloem with two-thirds of the root and it has broad cutting and putting vessel that formed 1-2 row. Heracleum hemsleyanum also has phloem with half of the root and wide scattered latex tube and many large vessel. 3. At the TLC pattern, Heracleum hemsleyanum has remarkable dark spot at $R_{f}$ 0.23 on the sulphuric acid color pattern test, but others have faint. 4. At the HPLC pattern, all samples have generally patterns. But Angelica pubescens f. biserrata shows diminutive continentalic acid content and the peak at Rt 20.278min comes out on Heracleum hemsleyanum, but do not come out on Aralia continentalis and Angelica pubescens f. biserrata. Heracleum hemsleyanum has remarkable peak at Rt 20.278min, but shows no peak at Rt 29.023min unlike Aralia continentalis or Angelica pubescens f. biserrata. Also Aralia continentalis and Angelica pubescens f. biserrata show one remarkable peak at Rt 29.023, but Heracleum hemsleyanum do not show. Consequently, Aralia continentalis and Angelica pubescens f. biserrata are comparable whit continentalic acid content and Heracleum hemsleyanum is comparable with the peak at Rt 20.273 and Rt 29.023. So it is thought that content of continentalic acid and the peaks at Rt 20.278 and Rt 29.023 can apply to differentiate a species from other. It is considered the results of this study will be furnished the basis to succeeding studies and it is needed to extensive comparative study for the same genus-degree of relatedness.

• 대한한방부인과학회지
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• 제24권4호
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• pp.194-204
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• 2011

Purpose: Many infertile women are receiving in vitro fertilization-embryo transfer (IVF-ET). But side effects occur after IVF-ET and pregnancy rate is still low. So this study is to report the effect of herbal medicine on a woman receiving IVF-ET and herbal medicine's low risk on a pregnant woman. Methods: The patient was underwent artificial insemination five times and IVF-ET three times. In this study, the patient steadily took a herbal medicine before IVF-ET to birth. Results: The side effects of IVF-ET and the miscarriage symptoms ware decreased. And by taking a herbal medicine during IVF-ET, the patient was pregnant and gave birth when she was 33 weeks pregnant by cesarian section. Conclusions: This case study shows that herbal medicine is effective for reducing side effects of IVF-ET and increasing pregnancy rate. And in this case the patient gave birth to healthy babies, althogh steadily taking herbal medicine during pregnancy.

• 혜화의학회지
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• 제5권2호
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• pp.513-522
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• 1997

Clinical studies were done on 94 patients with the General Pain after Childbirth(GPC). which were treated in Dept. of Oriental Gynecology. Oriental Medical Hospital. Dae Jeon University from July 1st 1995 to June 30th 1996. 1. The total incidence of GPC was about 13.2% of the 1162patients. 2. In age distribution of GPC. after twenty years old was the most in 40.4%. the next ration was thirty years old. forty years old. early twenty years old. 3. In inducing factor. overlook was the most in 29.8%. the next ration was delivery itself. difficult delivery. cesarean section in 26.6%. 4. In therapeutic response. excellence was the most in 38.3%. the next ration was improvement. good. non improvement. 5. In onset. within ten days of postpartum was the most in 35%. the next ration was from 11 to 30 days. from 91 to 180 days. during the period of pregnancy. from 61 to 90 days. from 180 to 360 days. 6. Remedical value of abortion was relatively emedical value of difficult delivery. Cesarean section was bad. 7. In delivery times. abortion times and pregnant times did not concern therapeutic response. 8. In therapeutic period. from 11 to 30 days was the most in 46.8%. 9. In delivery seasons. Feburary was the most in 15.9%. and there were many occurrence of GPC in the winter season. 10. Past history did not concern GPC. 11. In prescriptions. Bohuh Tang Kamibang(B) was the most in 33%.

• 대한한의정보학회지
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• 제18권1호
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• pp.64-77
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• 2012

Donguibogam, Korea's cultural heritage and traditional Oriental medicine book listed in the World Heritage three years ago, is indeed great in its importance and value. Korea's posterity has sought treatment methods through the medical book and their researches on that book have continued. However, it is rare to make the concrete analysis on the medicines for prescriptions recorded in the book. In this study, we reviewed "Ears" in the Section "Bodily Appearance" among the five chapters of Donguibogam, and analyzed the 55 types of prescriptions for ear diseases, the medical characteristics, tastes, prime classification of medical herbs, and acupunctural effects, and the dosage forms depending on prescriptions. For insect-entering ear diseases and 20 kinds of a single-medicine prescription also, the treatments are presented in the book, but we presented the texts only and excluded them in the analysis. We also excluded overlapping prescriptions and adding and reducing prescriptions of the 55 prescriptions, and thus classified the left 42 proscriptions by dosage form. As a result: 1. With respect to medical characteristics, the medicine with warm characteristics reached 9 types(40.9%), the highest rate, followed by the medicine with cold characteristics 8 types (36.4%). 2. Concerning medical tastes, the medicine with bitter taste included 12 types (54.5%), the medicine with sour taste 10 types (45.5%), and the medicine with sweet taste 7 types (31.8%). It was unusual that of the 22 medicines used for multipurpose, no medicine with the taste was found. 3. For the acupunctural effects, the medicine with acupuncture effects for spleen medirian reached 12 types in total (54.5%). On the contrary, the medicine with the effects for pericardium meridian reached only one (4.5%) among the total of 22 medicines. 4. In the dosage form of 42 prescriptions, powder medicine was 15 types (35.7%), and decoction medicine was 14 (33.3%). Powder, dedoction, and pill medicines accounted for 90.4% of the total medicine type. It was found that in particular, for ear diseases powder medicine was used more frequently than decoction medicine.

• 대한한의학원전학회지
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• 제27권3호
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• pp.47-66
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• 2014

Objectives : Evaluating water and its comparisons to Yin(陰) and Yang(陽). In this section, we will look into this matter from Dongeuibogam(東醫寶鑑) and introduce an oriental perspective on the subject of water(水部). Methods : Translating Eumchanboksikjeon(飮饌服食牋) from Junsangpaljeon(遵生八牋). An in depth study of related contents and comparing to the water section(水部) of Dongeuibogam(東醫寶鑑) Results : According to the section of Varieties of Teas and Water(茶泉類) in The Discussion of Springs(論泉水), Goryum(高濂) divided water into five different types in Eumchanboksikjeon(飮饌服食牋) of Junsangpaljeon(遵生八牋). These different types are Water that runs between rocks, Clear and cold water, Sweet and fragrant water, Spiritual water and Well water. Dongeuibogam(東醫寶鑑) also analyzed 28 different types of water out the 33 its list. The idea is that one must use water differently according its origins, where it originated, when and what season to maximize the usage of the water because the energy of water would be different. Conclusions : By evaluating water, we have learned that water picks up energy and changes according to its surrounding environments. The different types of water used changes the medicinal ingredients and it affects the human body differently. One must keep in mind, the cycles of water, its energy and how it helps us live a healthier life.

• 사상체질의학회지
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• 제20권2호
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• pp.164-170
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• 2008

1. Objectives This is a case of refractory ascites due to hepatocellular carcinoma treated with Sasang Constitutional Medication. Refractory ascites, which did not respond to diuretics, was improved with Jeoryeongchajeonja-tang. 2. Methods We recorded the patient's abdominal circumference, body weight and urine output daily. We also investigated the TTKG(transtubular potassium gradient) values 3 times during the treatment course. 3. Results the TTKG value of the patient was siginificantly decreased. TTKG values before administration of Jeotyeongchajeonja-tang were 8.41, 10.82, respectively and 4.25 after administration of Jeotyeongchajeonja-tang. 4. Conclusions We guess that Jeoryeongchajeonja-tang functions as an aldosterone antagonist or increases spironolactone activity through interaction between Jeotyeongchajeonja-tang and spironolactone. But the mechanism of Jeotyeongchajeonja-tang is not clear, so we need more clinical study of refractory ascites improved with Jeotyeongchajeonja-tang and biological study of interaction between Jeotyeongchajeonja-tang and spironolactone.

• 대한한방체열의학회지
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• 제6권1호
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• pp.49-55
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• 2008

Purpose: During Postpartum period many women complain multiple pain, cold hypersensitivity, hot flush, sweating and so on. We call the postpartum disease as San Hu Pung. We studied characters of DITI Characters of women suffering from Postpartum disease. Methods: We studied 55 patients visiting OOhospital from February 2006 to November 2007. The subjects were categorized in two groups, symptom group(37) and no symptom group(18). We measured the temperatures of abdomen(CV17, CV12, CV4), upper and lower limb(PC8, LU4, LR3, ST32) and back(GB21, BL18, BL53). We studied the difference of DITI between two groups by Student T-test using SPSS for windows (version 12.0). Results: The general characteristics such as age, days of postpartum, primiparity, cesarean section, partum season, breast-feeding of two groups were not different statistically. Temperatures of abdomen(CV17, CV12, CV4) and back(GB21, BL18, BL53) of two groups were not different statistically. Temperatures of Lt. PC8 and both LR3 of symptom group were statistically higher than no symptom group. The difference between Lt. PC8 and LU4, both LR3 and ST32 of symptom group were statistically higher than no symptom group. Conclusion: The results suggest that women suffering from Postpartum disease shows high temperature on hand and foot. It seems that postpartum disease patients tend to have blood deficiency. DITI can be useful to diagnose San Hu Pung. The more studies to diagnose San Hu Pung would be needed.

• 한국한의학연구원논문집
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• 제16권2호
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• pp.143-157
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• 2010

Objectives : The objective of this study was to access the effect of Artemisiae capillaris herba Extracts on the organogenetic reproductive toxicity of New Zealand White rabbits when administered by oral gavage. Methods : Gestational New Zealand White rabbits were dosed from 6 days of gestation to 18 days of gestation. It was conducted in accordance with the recommendations of the KFDA Guideline for Detection of Toxicity to Reproduction for Medicinal Products. In addition, serum AST, ALT, LDH and ALP levels were detected with their necropsy and histopathological observation Results: No significant changes of body weights, gains and food consumption were demonstrated in all dosed groups compared to those of vehicle control group except for 2,000mg/kg-dosing group, which showed significantly increase of body weight compared to that of vehicle control group. Normal gross findings were demonstrated in all tested groups. No significant changes of number of corpora lutea, implantation, implantation rate, number of fetal death, loss rate of post-implantation, number of live youngs at C-section, survival rate of post-implantation, number of male live youngs at C-section, number of female live youngs, sex ratio of live young, external anomalies of live youngs and body weight of live youngs were demonstrated in all dosed groups compared to those of vehicle control group. Although some visceral variations such as thymic reminant in the neck, dilation of renal pelvis, dilated ureter and malpositioned left common carotid artery, no significant changes were demonstrated in all dosed groups compared to that of vehicle control group. Some malformations and variation were demonstrated with retardations. However, no significant changes were demonstrated in all dosed groups compared to that of vehicle control group. In addition, similar ossification numbers were detected in sternebrae, metacarpals, metatarsals, phalanges, cervical vertebrae, and sacral and caudal vertebrae. No Artemisiae capillaris herba Extracts treatment-related changes of serum AST, ALT, LDH and ALP levels were demonstrated in all dosed levels in this study. Conclusions : We could conclude that oral administration of Artemisiae capillaris herba Extracts hasn't an influence on the organogenetic reproductive toxicity.

• 동의신경정신과학회지
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• 제22권2호
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• pp.177-198
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• 2011

Objectives : By analyzing and comparing indications, components and their doses of herb medicines, which were recorded in insomnia chapters of medical books, we examined historical changes and made clear documentary ground of medications. Methods : 1. 10 books which were noted in insomnia part of "The Eastern Medical Textbook of neuropsychiatry" and 13 books were mentioned in same part of "Uibujeonrok" were selected as reference. 2. We searched article database such as KISS, riss4U and journals issued by the Korean society of oriental neuropsychiatry. Finally, 39 books which were noted in 3 literature reviews, were chose as reference. 3. In reference books, we collected the herb medicines in chapters related to insomnia. 4. In case of no section associated with insomnia in books, we found prescriptions related to insomnia in whole chapters. 5. If the chief virtue of medication was not primarily for insomnia, we excluded applied or added herb medicines. 6. We classified prescriptions into small groups which had same name, and then rearranged them in chronological order. Results and Conclusions : 1. Banha-tang(banxiatang) of "Hwangjenaegyeong Youngchu" was the first-recorded prescription used for insomnia. 2. The chapter of insomnia appeared in "Chunkeumyobang" at first. 3. Ondam-tang(Wendantang) was most cited prescription in medical books. It was recorded totally 19 books from "Chunkeumyobang" to "Hyeoljeungron". 4. We suspects indications, components, dosage of medication of insomnia in Donguibogam were revised according to author's clinical experience and circumstances.

• 동의생리병리학회지
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• 제18권6호
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• pp.1777-1783
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• 2004

This study was conducted to determine the effects Wonjiseokchangpo-san on brain damage in transient focal cerebral ischemia. Rats were used for testing in the following three models: Morris Water Maze, Eight-Arm Radial Maze, and Histochemistry. In the Morris Water Maze Model, the Wonjiseokchangpo-san group showed significant decrease in the 3rd and 6th training session compared with the ischemia group. A retention test, in the Morris Water Maze Model, was performed on the 7th day without the escape platform. The Wonjiseokchangpo-san group showed significant increase compared to the ischemia group. In the Eight-Arm radial Maze model, the Wonjiseokchangpo-san group showed significant decrease in the error rate compared to the ischemia group. In the density of hippocampal CA1 cell of the cresyl violet-stained section, the Wonjiseokahangpo-san group showed significant increase compared to the ischemia group. These results suggest that Wonjiseokchangpo-san may have a significant protective effect on brain damage and cognitive dysfunction in transient focal cerebral ischemia.