Journal of Sasang Constitutional Medicine (사상체질의학회지)

The Society Of Sasang Constitutional Medicine (사상체질의학회)
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A Case of Refractory Ascites Due To Hepatocellular Carcinoma Treated with Sasang Constitutional Medicine

간세포암에 동반된 난치성 복수를 호전시킨 소양인 환자 치험1례

  • Jung, Yee-Hong (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Kyunghee Univ.) ;
  • Kim, Eun-Hee (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Kyunghee Univ.) ;
  • Seo, Young-Kwang (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Kyunghee Univ.) ;
  • Choi, Won-Cheol (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Kyunghee Univ.) ;
  • Lee, Soo-Kyung (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Kyunghee Univ.) ;
  • Eo, Wan-Kyu (Section of Hematology/Medical Oncology, Dept. of Internal Medicine, Mu integrative Cancer Center Kyunghee University East-West Neo Medical Center)
  • 정의홍 (경희대학교 한의과대학 사상체질과) ;
  • 김은희 (경희대학교 한의과대학 사상체질과) ;
  • 서영광 (경희대학교 한의과대학 사상체질과) ;
  • 최원철 (경희대학교 한의과대학 사상체질과) ;
  • 이수경 (경희대학교 한의과대학 사상체질과) ;
  • 어완규 (경희대학교 동서신의학병원 M . u통합암센터 혈액종양내과)
  • Published : 2008.08.30
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Abstract

1. Objectives This is a case of refractory ascites due to hepatocellular carcinoma treated with Sasang Constitutional Medication. Refractory ascites, which did not respond to diuretics, was improved with Jeoryeongchajeonja-tang. 2. Methods We recorded the patient's abdominal circumference, body weight and urine output daily. We also investigated the TTKG(transtubular potassium gradient) values 3 times during the treatment course. 3. Results the TTKG value of the patient was siginificantly decreased. TTKG values before administration of Jeotyeongchajeonja-tang were 8.41, 10.82, respectively and 4.25 after administration of Jeotyeongchajeonja-tang. 4. Conclusions We guess that Jeoryeongchajeonja-tang functions as an aldosterone antagonist or increases spironolactone activity through interaction between Jeotyeongchajeonja-tang and spironolactone. But the mechanism of Jeotyeongchajeonja-tang is not clear, so we need more clinical study of refractory ascites improved with Jeotyeongchajeonja-tang and biological study of interaction between Jeotyeongchajeonja-tang and spironolactone.

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