• Advances in Traditional Medicine
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• v.5 no.2
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• pp.100-109
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• 2005

In South America, natural products with unknown drug effects are used as folk remedies and for preventive medicine. Among South American natural products, we directed our attention to Propolis, which have been known as medicinal plants, and examined the mechanisms by which these substances affect antioxidant activity, anti-tumor activity and immunoresponse. When the antioxidant activities of Propolis were examined by the DPPH and Rhoudan iron methods, since Propolis contains high levels of flavonoids, it is thought that flavonoids may be responsible for the antioxidant activity in this study. In the examination of immunoenhancement activity, we measured lymphocyte versus polymorphonuclear leukocyte ratios (L/P activity). The number of lymphocytes was significantly increased in groups treated with Proplolis. Specifically, slightly high levels of $IFN-{\gamma}$ were measured in mice bearing the S-180 carcinoma, after administration of Propolis. This strongly suggests that cellular immunity is especially activated by treatment with Propolis, because production of $IFN-{\alpha}$ is limited to the T cells and NK cells stimulated by mitogen and sensitized antigen. $TNF-{\alpha}$ shows a different extent and mechanism of action depending on the target cells. When $TNF-{\alpha}$ was measured in mice bearing the S-180 carcinoma, mice treated with Propolis showed slightly higher $TNF-{\alpha}$ levels as compared to the control group. This suggests that activated macrophages produce $TNF-{\alpha}$ in mice treated with Prapolis, since activated macrophages and lymphocytes are the source of most $TNF-{\alpha}$. When anti-tumor action was examined using two kinds of sarcoma (Ehrlich solid carcinoma and Sarcoma-180 carcinoma), tumor-suppressive ratios after treatment with Propolis was 29.1%. When Sarcoma-180 solid carcinoma was used, tumor-suppressive ratios were 62%. Thus, Propolis showed strong anti-tumor activity against two kinds of solid carcinoma. Taken altogether, this strongly suggests that Propolis enhances original functions of macrophages and NK cells, and as a result, secondarily enhances the immune reaction and suppresses tumor growth.

• Korean Journal of Acupuncture
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• v.21 no.3
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• pp.21-38
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• 2004

Objectives : Moxibustion has been become very useful tool to prevent and treat various diseases with acupuncture in oriental medicine. Expecially, moxibustion combining the heat stimulation and chemical stimulation of Artemisiae Argyi has a non-invasive characteristics comparing to the other therapeutic tools. However, because the moxibustion makes the patient's skin be burn by the combustible feature of moxibustion, most of people have been scared of being scald. Methods : In this study, we have developed new non-combustible moxibustion tools in collaboration with company (Hana Medical, co. and ICURE, co.) and tested the efficacy through effects of moxibustion of Cheon-chu $(ST_{25})$ on the abdominal thermography of health subject. The non-combustible moxibustion has main characteristics of controlled heating to inhibit being scald and heat stimulation lasting over 1 hrs. Also, to induce the chemical stimulation, the bottom contacting with skin was coated by the extract of artemisiae argyi. The volunteers who participating in this study had taken rest for 20 - 30 mins in room temperature $(23-25^{\circ}C)$ before the examination and informed them what to prohibit smoking, drinking and administration of drug for the previous day The thermography of abdomen including a below part of the chest was taken using Infra-Red Imaging System (IR 2000, MEDI-CORE Co., Korea) by time interval of 15 minutes. Results : The results showed that moxibustion of Cheon-chu $(ST_{25})$ had more potencies of changes on all the ROIs of abdominal thermography than those of control group. Also, it was observed that the quantities of thermal changes following moxibustion of Cheon-chu $(ST_{25})$ been increased significantly comparing that of control group at all the ROIs (region of interest). Observed the thermography classified by ROI, however, moxibustion of Cheon-chu $(ST_{25})$ could modulate ipsilateral specific areas concerning to the abdominal pathway of Stomach Meridian. Conclusion : These results suggest that new non-combustible moxibusion has some similarity as like as the conventional moxibustion and moxibustion of Cheon-chu $(ST_{25})$ may modulate thermal changes of abdominal areas.

• Journal of Sasang Constitutional Medicine
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• v.10 no.2
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• pp.181-220
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• 1998

1. PURPOSE This is a quantitative analysis of Sasang Constitution by measuring human body except face. This study is carried out for the purpose of searching out the theory of Sa-cho and the morphologic theory of Sasang Constitution. 2. METHOD (1) SUBJECTS Subjects are 338 person came to Dept. of Sasang Constitutional Medicine (KyungHee Oriental Medical Center) and Oriental Medicine and Western Medicine Cooperative Health Examination Center (KyungHee Medical Center) from October 1997 to Jauary 1998. The mean age is $41.7{\pm}12.39$. (2) CLASSIFICATION OF SASANG CONSTITUTION QSCCII(Questionnaire for the Sasang Constitution Classification) is used for the Classification of Sasang Constitution. The distributions of Sasang Constitution Classification are Soeumin 83, Soyangin 98, and Taeumin 157. (3) MEASURING INSTRUMENT & ITEMS Length, Breadth, Circomferece, and Skinfold thickness of each body segment are measured by Martin's measuring instrument and Skinfold Caliper. Measured items of this study is based on Lohman's methods and is added new items. (4) DATA ANALYSIS The Volume, Weight, Rate, and Index of each group are calculated by using measuring items. The difference of each group is analyzed by SPSS 7.0 for Win. 3. RESULT (1) THE MORPHOLOGIC CHARACTERISTIC of TAEUMIN First of all, the Taeumin has a emormous morphology. His trunk is huge but head-neck and limbs is small. The volume and weight of head-neck is smaller than other body segments but the volume and weight of upper-abdomen is bigger than ones. (2) THE MORPHOLOGIC CHARACTERISTIC of SOEUMIN The Soeumin has a small morphology. His head-neck rate is bigger than Taeumin's but his trunk rate is smaller than Taeumin's. And his lower limbs rate is bigger than other constitution but it's not a significant difference. His neck is thinest and longgest than others. His chest is thin and narrow. His lower-abdomen rate is bigger than other constitution but it's difference is not significant. (3) THE MORPHOLOGIC CHARACTERISTIC of SOYANGIN Soyangin has a middle size at head-neck and chest part. But the rate of upper limb is higer than other constitution. And the rate of lower-abdomen part is lower than other constitution. but that's not significant.

• Journal of Society of Preventive Korean Medicine
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• v.5 no.1
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• pp.10-30
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• 2001

Oriental medicine needs to be armed with theories on health-improvement concept under it and basic data matching its views, in order to participate in the health-improvement service in industrial work places. The Orient medicine health-improvement program defines factors that determine individuals' lifestyle, and provides information and technologies for workers to practice in life. To that end, this research compares and analyzes health-improvement concept and health care, defines relations between individuals' health state and their lifestyle as the basic data needed to perform health-improvement business for workers. 1. The subjects employed for this research is categorized into; by gender, males 52.1% and females 47.9% with no big difference between them; and by age, 20s, 6.1%, 30s. 33.9%, 40s, 34.1%, and 50s, 24.8% with 30-50 accounting for most of it. By marriage status, unmarried represents 7.1%, and married 79.1% with most of them married; by revenue, under one million won represents 3.0%, 1-2 million won 26.4%, 2-2.49 million won 11.2%, above 2.5 million won 11.2%, and 1-2.5 million won a majority. By living location, owned houses represents 65.4%, rented houses 14.7%, monthly-rented 9.5%; and by education, elementary and middle school represent 16.9%, high school and its dropouts 22.6%, and junior college and higher 51.6%, with high school and higher occupying most of the group. 2. By job, office workers and managerial workers represent 12.3%, part-timers 21.0%, manual workers 11.4%, jobless 0.6%, professionals 35.6%, service 0.6%, housewives 8.4%, and equipment/machinery operation/assemblers 10.1%. Of this, jobless and part-timers, totaling three, are dropped from this research. By years worked, 0-3.9 years represents 9.7%, 4-7.9 years 6.7%, 8-14.9 years 18.4%, above 15 years 28.7%, and no respondents 36.5%. 3. The degree of the subjects practicing life-improvement lifestyle, on a scale of 1 to 4, is an average of 2.69, personal relations 3.04, self-realization 2.92, stress management 2.76, nutritional state 2.73, responsibility for health 2.47, and athletic activities 2.18, with personal relations earning the highest points and athletic activities the lowest. As for factors influencing health-improvement lifestyle, there is no significant difference between gender, age, and marriage status. Meanwhile, there is significant difference between revenue, dwelling pattern, education level, etc. That is, higher income-bracket, owned houses, rented houses, monthly-rented houses, and higher-educated, in this order, show higher average in health-enhancement lifestyle. By job, housewives, manual workers, office workers, professionals, equipment/ machinery operation/ assemblers, and part-timers, in this order show higher points, while there is no difference with significance by years worked. 4. Factors that affect health-improvement lifestyle are shown below. Self-realization is influenced by age, marriage status, type of dwellings, and level of education; responsibility for health by type of dwellings; athletic activities by gender and age; nutrition by age, marriage status and type of dwellings; personal relations by marriage status; and stress management by type of dwellings. 5. Areas with high points by job show this: in self-realization, office workers, manual workers, housewives, professionals, equipment/ machinery operation/ assemblers, in this order, show difference with significance; in the area of responsibility for health, manual workers, housewives, equipment/ machinery operation/ assemblers, professionals, office workers and part-timers, in this order, do. In athletic activities, manual workers, housewives, office workers, professionals, equipment/ machinery operation/ assemblers, and part-timers, in this order, show difference with significance; in nutrition, housewives, office workers, manual workers, professionals, equipment/ machinery operation/ assemblers, and part-timers, in this order do; and in stress, housewives, office workers, manual workers, professionals, equipment/ machinery operation/ assemblers, part-timers, in this order do. By years worked, more years showed higher points in the area of responsibility for health and nutrition; in the area of athletic activities, above 15 years, 4-8 years, below 4 years and 8-14 years, in this order, show higher points; and no difference shows in realization, personal relation, and stress area. 6. To look at correlation between overall and divisional health-improvement practice degree, this researcher has analyzed it using Person's correlation coefficient. Self-realization, responsibility for health, athletic activities, nutrition, support for personal relations, and stress management show significant correlation with the sub-divisions, while all health-improvement lifestyle shows significant correlation with the six sub-divisions.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.6
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• pp.1493-1499
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• 2003

This study was examined for effects of acupuncture of Chok-Samni(ST36) on the facial thermography in health subjects, The volunteers who participating in this study had taken rest for 15 mins in room temperature (19-21 ℃) before the examination and informed them what to prohibit smoking, drinking and administration of drug for the previous day, The thermography of face was taken using Digital Infrared Thermographic Imaging (D.I.T.I. : Dorex, DTI-16UT1, U.S.A.) by time interval of 35 minutes at 15 min before and 20 min after acupuncture stimulation. Thermal temperature of Yangbaek(GB14), Myon-koryo(ST3) and Chichang(ST4) was measured and compared, The results showed that acupuncture of Chok-Samni(ST36) decreased the Absolute difference of temperature between Myon-koryo(ST3) and Chichang(ST4) (p<0,05, Data were represented mean±S,E.M.(n=33)), But, acupuncture of Chok-Samni(ST36) particularly decreased the absolute difference of temperature between Yangbaek(GB14) and Chichang(ST4) and particularly decreased the absolute difference of temperature between Vangbaek(GB14) and Myon-koryo(ST3) (p<0,05, Data were represented mean±S,E.M.(n=33)). Also, it was observed that acupuncture of Chok-Samni(ST36) decreased variety of the color tone of thermographic contour line and decreased thermal distribution. The results showed that acupuncture of Chok-5amni(ST36) significantly decreased the absolute difference of temperature of partial facial surface. Hereafter, study about if acupuncture of Chok-Samni(ST36) significantly decrease the absolute difference of temperature of all the areas of facial surface is requested. Also, continued study of effects of acupuncture of other meridian on the facial thermography is requested.

• Journal of Korean Medicine Rehabilitation
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• v.24 no.4
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• pp.61-70
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• 2014

Objectives The purpose of this study was to investigate the characteristics in obesity classification group of college students having health checkup by analyzing their BMI and blood test and determine the association between factors contributing to obesity and obesity according to BMI. Methods A group of 2992 test subjects took their medical examination and their body composition, height, weight, blood pressure were measured and blood test was done. With these results we diagnosed obesity, and analysed relationship between obesity and cholesterol, triglyceride, LDL (low density lipoprotein)-cholesterol, HDL (high density lipoprotein)-cholesterol, liver function, renal function and blood pressure. Results 1. Overweight individuals showed high total cholesterol, LDL-cholesterol, triglyceride, GOT (glutamic oxalacetic transaminase), GPT (glutamic pyruvate transaminase), Urea-nitrogen, Creatinine and low HDL-cholesterol. 2. BMI showed a significant association with other factors. BMI has a negative correlation with sex and HDL-cholesterol. BMI had positive correlations with other factors. 3. There was no relation between BMI and sex. Those six factors, liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar were related to BMI. Conclusions There was a significant relation between college students' BMI and their liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar. The diseases related to liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar were clearly associated with obesity.

• Journal of Society of Preventive Korean Medicine
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• v.15 no.3
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• pp.153-162
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• 2011

Objectives : This study has aimed to monitor microbial detection on pill types of herbal medicine which are circulating in markets including Oriental Medical Clinics(O.M.C.s) and Pharmacy in Korea. Methods : 10 different samples of O.M.Cs and 10 different samples of Pharmacy were investigated by culture method and non-culture method based on the 9th edition of microbial examination released by Korea Food & Drug Administration. Results : The total microbial count among each 10 samples were detected within the limit suggested by WHO. 2 samples of O.M.C.s and 1 samples of Pharmacy exceeded WHO's limit in fungi count. No samples exceeded WHO's limit in bacteria count. Most bacteria founded in samples were the phylum of Firmicutes and Proteobacteria which are common in soil by non-culture method. Conclusion : Further study should be followed to set up proper microbial limit of herbal materials including pill types.

• The Journal of Internal Korean Medicine
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• v.23 no.1
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• pp.25-31
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• 2002

Objectives : To prevent stroke, it is very important to reduce risk factors which might cause stroke. However, previous studies that having investigated coffee consumption associated with stroke reported various results. In addition, there were only a few studies based on the Korean population. Therefore, we studied the association of coffee consumption and the possibility of getting stroke among Koreans. Methods : A case-control study was carried out on 207 cases(stroke patients) and 207 controls(non-stroke patients) in a hospital. Information on characteristics, health habits, dietary habits and coffee consumption were obtained through direct interview by using an organized questionnaire; WHR(Waist-Hip Ratio) was determined through physical examination. The coffee consumption was classified by the average frequency of intake, such as less than 1 cup/day, 2-3 cups/day, more than 5 cups/day). Possible confounding effects of age, sex, smoking and alcohol drinking were controlled by multiple logistically regressive analysis. Results : After adjusting age and sex, coffee consumption significantly increased risk factors of stroke(${\leq}$1 cup/day OR=1.018, 95% CI=0.631-1.644; 2-3 cup/day OR=1.782, 95%CI=1.032-3.079;${\geq}$5 cup/day OR=1.210, 95% CI=0.588-2.490). When other factors were controlled, the risk factors of stroke were associated with alcohol drinking, whereas no significant association was observed with coffee consumption. Conclusion : Coffee consumption is not a major risk factor of causing stroke in this study. Prospective and cohort study on the association between coffee consumption and the possibility of getting strokes among the Korean population will be needed in the future.

• Journal of Society of Preventive Korean Medicine
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• v.23 no.3
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• pp.21-30
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• 2019

Objective : The study aimed to report the results of workplace-based Korean Medicine cohort, The cohort collected the health information including physical measurements, questionnaires, and biomarkers. Method : This study was conducted on 200 faculty members of two hospitals and two universities in 2017 through 2018. The study analyzed physical measurement, cold-heat questionnaire, body compositions and pulse characteristics. Result : The heat-cold score, waist circumference, visceral fat area, and body water were different according to the Sasang constitution, in order of Taeum > Soyang > Soeum. The pulse energy difference was shown only in women. Conclusion : There were differences in body composition such as heat point, waist circumference, internal fat area and body water content by constitution, and also difference by body mass in total energy in pulse examination. It is believed that there were significant relation between physical, physical and energy metabolic aspects through Sasang constitution.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.6 no.4
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• pp.610-615
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• 2002

Being a medium to help understand the status of the whole body including the Five Vital Organs and the Six Viscera such as the heart, the mac is considered to represent the elasticity of the blood vessel and the condition of the bloodstream in the Oriental medicine. A doctor makes a subjective judgment on a patient's conditions based on the information derived from the diagnosis and the medical examination of the mac wave. Thus he or she needs objective records and make a decision based on them in order to prevent misdiagnosis. This paper set out to suggest the ways to detect the particular parameters of the mac wave with the methods to visualize the mac wave interpretation to detect basic documents(causes) of health status judgment in three-dimension and with the simulation.