Abstract
Objectives : This study has aimed to monitor microbial detection on pill types of herbal medicine which are circulating in markets including Oriental Medical Clinics(O.M.C.s) and Pharmacy in Korea. Methods : 10 different samples of O.M.Cs and 10 different samples of Pharmacy were investigated by culture method and non-culture method based on the 9th edition of microbial examination released by Korea Food & Drug Administration. Results : The total microbial count among each 10 samples were detected within the limit suggested by WHO. 2 samples of O.M.C.s and 1 samples of Pharmacy exceeded WHO's limit in fungi count. No samples exceeded WHO's limit in bacteria count. Most bacteria founded in samples were the phylum of Firmicutes and Proteobacteria which are common in soil by non-culture method. Conclusion : Further study should be followed to set up proper microbial limit of herbal materials including pill types.
1. 서울, 경기소재 한의원에서 환약 10종과 경기소재 약국1곳에서 판매되는 한방환약 10종, 총 20종의 환약에 대해 미생물검출연구를 하였다. 2. 총세균수는 한의원환약, 약국환약에서 모두 WHO기준(1.0${\times}$107) 이내로 검출되었다. 3. 총진균수는 한의원환약, 약국환약의 각각 2종류, 1개제품에서 WHO기준(1.0${\times}$104)을 초과 하였다. 4. 배양 비의존적 방법을 이용하여 환약에 분포하는 Bacteria를 동정한 결과, 대부분의 박테리아는 토양에 존재하는 Firmicutes문, Proteobacteria문의 두 종류에 속하였다. 5. 환약의 안전성을 제고하기 위해, 생산, 가공, 유통, 보관 등 각 단계에서의 추가적인 미생물검출연구가 필요하다.
