• Natural Product Sciences
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• 제1권1호
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• pp.5-9
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• 1995

The metabolites of marine mollusk Mytilus edulis were isolated and characterized, revealing the presence of the rare free fatty acids and proteinogenic amino acids together with a non-proteinogenic free amino acid, taurine. The free fatty acids in this organism were particularly interesting for the presence of both unusual n-6 acid [20:4 (n-6)] and triple bond containing acid (2,5-octadecadiynoic acid). In addition to the proteinogenic amino acids commonly found in proteins, non-proteinogenic free amino acid taurine was isolated and the structure was determined by its physicochemical properties. Recently taurine has been given much interest in the molecular level because of diverse biological activities and the medicinal properties. Furthermore, the result of the analyses of analyses of free amino acids showed that glycine, glutamic acid, serine and alanine, which were considered to be related to the taste of this organism, are predominantly present.

• 한국물환경학회지
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• 제29권4호
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• pp.497-503
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• 2013

The morphological characteristics of granules, which were generated in lab-scale sequencing batch reactor (SBR) for simultaneous nitrogen and phosphorus removal with denitrifying phosphorus accumulating organism (dPAO) were identified. Granular sludge was fully developed in the anaerobic-anoxic (An-Ax) SBR after 180 days of SBR operation. The average diameter of granular sludge was 2.2 mm and rod-type organisms dominated in the granules. In addition, about 1.0 mm of white precipitate was observed in the core of the granule, and the material was confirmed that it is very similar to hydroxyapatite $(HAP;\;Ca_5(PO_4)_3(OH))$ by X-ray diffraction) analysis.

• 한국균학회지
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• 제13권4호
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• pp.263-265
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• 1985

한국에 발생하는 배나무 검은별 무늬병 병원균의 특성과 병원성을 조사한 결과 한국에서 분리된 검은별 무늬병균의 분생자의 길이와 폭은 평균 $14.6-6.4\;{\mu}m$이었으며 분생자경의 길이와 폭은 평균 $13.5-4.6\;{\mu}m$이었다. 병원성 경정은 Flemish Beauty, Beurre Delicious, Winter Nelis (서양배), 신고(일본배)에 인공상처 접종한 결과 신고의 잎에서만 전형적인 검은별 무늬병의 병징이 재현 되었다. 이상의 결과로 보아 한국에서 발생하고 있는 배 검은별 무늬병균은 V. nashicola에 가까운 것으로 판정 되었다.

• 한국임상약학회지
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• 제2권1호
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• pp.41-53
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• 1992

This study was designed to estimate the ability of squalene treated mice to eliminate systemically infected bacteria and fungi and to elucidate the mechanism. As a result of measuring the ability to remove systemically infected bacteria and fungi, The ability of mice to remove the organism was found to increase in squalene treated mice when compared with control mice. And also the ability of phagocytic cells to produce Reactive Oxygen Intermediate(R.O.I.) increased in squalene treated mice. When the NADPH oxidase activity that make R.O.I. produce was measured, the activity increased in squalene treated mice, too. Therefore the good clearance of live organism in squalene treated mice is likely to relate to phagocytic cell activation. The activation of phagocytic cells might be mediated via the increased production of R.O.I. due to the increase of NADPH oxidase activity.

• 한국미생물·생명공학회지
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• 제9권2호
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• pp.77-82
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• 1981

Candide tropicalis was selected for its ability to utilize spent waste generated by the alcohol distillery using tapioca starch as a raw material. Optimum pH and temperature on batch culture of the organism were 4.0 and 3$0^{\circ}C$. The growth of the organism was markedly increased when 0.2% of ammonium sulfate, 0.002% of potassium phosphate dibasic, add 0.04% of magnesium sulfate were supplemented to the filtrate. At these conditions, maximum specific growth rate and saturation constant were 1.0 hr$^{-1}$ and 4.4 g.1$^{-1}$ , respectively. At a dilution rate of 0.5hr$^{-1}$ , a productivity of 1.84 g.1$^{-1}$ . hr$^{-1}$ was obtained and about 70% of carbohydrate was assimilated. Protein content of dried cell was about 60%.

• Journal of Chest Surgery
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• 제25권3호
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• pp.271-275
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• 1992

One hundred forty patients with empyema thoracis were managed under the general anesthesia at the Seoul National University Hospital between 1980 and 1990. The patients, who were managed by thoracentesis or intercostal tube drainage alone, were excluded in this study. There were 92 males and 48 females, ranging from 8 to 80 years of age. Underlying pathologic lesions of empyema thoracis were primary bronchopulmonary infection [84%], postoperative empyema[11%], malignancy, paragonimiasis, spontaneous pneumothorax and so on. A single causal organism was isolated only in 17 patients[the most common being staphylococcus aureus, pseudomonas, & streptacoccus pneumoniae], multiple organism in 31, and no growth in 32. Surgical treatment modalities were decortication[75], pleuropneumonectomy[30], decortication with lobectomy[10], empyemectomy[9], open drainage[13], Clagett procedure [6], thoracoplasty with or without muscle transposition[9]. Hospital mortality were in 2 cases[1.4%], one empyema related and the other nonrelated. In this study, bacteriologic findings were nonspecific and often polymicrobial. We conclude that early thoracotomy can be lifesaving in the presence of a benign clinical course.

• 한국시스템다이내믹스연구
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• 제7권2호
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• pp.215-226
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• 2006

A conceptual system dynamics model is developed to represent the dynamic mechanism between the number of hepatitis B virus and the defense system of the body. The simulation results shows that the model behaves within the reasonable ranges. The developed conceptual model is a first attempt to quantify the dynamic mechanisms of the hepatitis B virus, where only feedback structures are considered without bio-organism data. The next step would be to incorporate the model with bio-organism theory and to carry out case studies to identify personal characteristics. Since the current model is a conceptual model where quantitative results are not based on the sound background, the usage is limited only within the qualitative basis. It could be a effective educational tool for the patients. It also shows what-to-do lists in order to be used for forecast purposes.

• 대한두경부종양학회지
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• 제26권2호
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• pp.225-227
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• 2010

Actinomycosis is an unusual granulomatous infection caused by gram-positive anaerobic bacteria called Actinomyces species(predominantly Actinomyces israelii), which is a common and normally nonpathogenic organism found in the nose and throat. The three major clinical presentations of actinomycosis include the cervico-facial(the most common, 55%), thoracic, and abdominopelvic region. Actinomycosis typically has a chronic, indolent course characterized by swelling and induration of the soft tissues and eventual spontaneous drainage through multiple sinus tracts. Actinomycosis is difficult to diagnose because of variable presentation mimicking neoplasm and fastidious nature of the organism in culture. We present a case of actinomycosis in the parotid tip area which was mistaken for a salivary tumor.

• Journal of Microbiology and Biotechnology
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• 제15권5호
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• pp.1146-1151
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• 2005

The yeast Candida albicans has a distinguishing feature, dimorphism, which is the ability to switch between two morphological forms: a budding yeast form and a multicellular invasive filamentous form. This ability has been postulated to contribute to the virulence of this organism. Previously, we reported that the yeast-to-hypha transition in this organism is suppressed by farnesoic acid, a morphogenic autoregulatory substance that accumulates in the medium as the cells proliferate. In this study, using a differential display reverse transcription polymerase chain reaction (DDRT-PCR) technique, we have identified several genes induced in C. albicans by farnesoic acid treatment. These observations indicate that farnesoic acid can alter the expressivity of multiple genes, including the DNA replication machinery and cell-cycle-control proteins.

• Journal of Microbiology and Biotechnology
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• 제17권6호
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• pp.1049-1053
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• 2007

Tannase production by Aureobasidium pullulans DBS66 was optimized. The organism produced maximum tannase in the presence of 1% tannic acid after 36 h. Maximum gallic acid accumulation was observed within 36 h and tannic acid in the fermented broth was completely degraded after 42 h of growth. Glucose had a stimulatory effect on tannase synthesis at 0.1% (w/v) concentration. The organism showed maximum tannase production with $(NH_4)_2HPO_4$ as nitrogen source. Shaking speed of 120 rpm and 50-ml broth volume have been found to be suitable for maximum tannase production.