• 제목/요약/키워드: Order of growth

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일당귀 n-hexane분획이 에탄올을 투여한 흰쥐의 항산화계 및 지질과산화에 미치는 영향 (Effects of n-Hexane Fraction of Angelica acutiloba on Antioxidative System and Lipid peroxidation in Ethanol-Induced Hepatotoxicity of rats)

  • 추명희;최현숙;서영남;이명렬
    • 한국식품저장유통학회지
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    • 제11권3호
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    • pp.364-372
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    • 2004
  • 일당귀의 n-hexane분획이 횐쥐에서 에탄올투여로 생성된oxygen free radical대사와 지질과산화작용에 미치는 영향을검토하기 위하여 실험동물을 정상군, 일당귀 n-hexane 분획70 mg/kg투여군, 알코올투여군(35$\%$ ethanol 10 mL/kg, b.w./day), 알코올(35$\%$ ethanol 10 mL/kg, b.w./day) 및 일당귀 n-hexane 분획 70 mg/kg 병합투여군과 알코올(35$\%$ ethanol 10mL/kg, b.w./day) 및 일당귀 n-hexane 분획 140 mL/kg 병합투여군의 5군으로 나누어 6주간 사육하여 체중증가율, 식이효율 및 혈청중 ALT, AST 측정과 간손상 억제효과를 검토하기 위하여 간조직중 유리기 생성계 효소인 XO활성, 유리기해독계 효소인 SOD, calaase 및 GSH-Px활성과 지질과산화물인 TBARS 및 GSH함량을 측정한 결과는 다음과 같다. 각 분획의 항산화력은 n-hexane, ethylacetate, chloroform,n-butanol 및 water 분획순으로, n-hexane 분획의 항산화력이가장 우수하였다. 6주간의 체중증가율과 식이효율은 알코올투여로 정상군에 비하여 유의적으로 저하되었으나 일당귀 n-hexane 분획투여로 정상군에 근접하게 상승되었고, 알코올투여로 상승된ALT 및 AST활성도 유의하게 저하되었다. 간 조직중 XO활성은 알코올투여로 정상군보다 상승되었으며 일당귀 n-hexane 분획 투여로 저하는 되었지만 유의성 있는 변화는 아니었다. 알코을 투여로 상승된 SOD활성은일당귀 n-hexane 분획 투여로 정상군에 비하여 유의하게 저하되었으나 catalase와 GSH-Px활성은 유의적인 변화를 나타내지 않았다. TBA 반응성 산물량은 정상군과 일당귀 n-hexane 분획 투여군간에 차이는 없었고 알코올투여로 정상군보다 많은 증가를 나타냈으나 일당귀 n-hexane 분획투여로 정상군에 근접하게 감소되었다. 알코올투여로 감소된 GSH 함량은 일당귀 n-hexane분획을 투여하여 용량의존적으로 증가되었다. 이상의 실험결과에서 일당귀의 항산화작용은 유리기 해독계 효소인 SOD활성억제와 비효소적 항산화작용을 나타내는GSH량을 증가시킴으로서 지질과산화물에 대한 방어력이 증강되어 나타난 결과로 판단되어지며, 또한 혈청중 ALT 및AST활성을 유의성있게 감소시키므로써 일당귀가 알코올성 간질환에서 손상된 간기능을 회복시킬 수 있을 것으로 추정되었다.

체외수정 생쥐 배아에서의 배아 줄기세포 확립 (Establishment of Mouse Embryonic Stem Cell-like Cells from In Vitro Fertilized Embryos)

  • 문신용;박용빈;김희선;오선경;천대우;서창석;최영민;김정구;이진용;김석현
    • Clinical and Experimental Reproductive Medicine
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    • 제29권1호
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    • pp.1-12
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    • 2002
  • Objective: In order to acquire the technique for the establishment of human embryonic stem cells (ESe) derived from the human frozen-thawed embryos produced in IVF-ET program, this study was performed to establish mouse ESC derived from the in vitro fertilized embryos. Materials and Methods: After Fl hybrid (C57BL female $\times$ CBA mael) female mice were superovulated with PMSG and hCG treatment, their oocytes were retrieved and inseminated, and the fertilized embryos were cultured for 96-120 hours until the expected stages of blastocysts were obtained. To isolate the inner cell mass (ICM), either the blastocysts were treated with immunosurgery, or the whole embryos were cultured for 4 days. Isolated ICMs were then cultured onto STO feeder cell layer, and the resultant ICM colonies were subcultured with trypsin-EDTA treatment. During the subculture process, ESC-like cell colonies were observed with phase contrast microscopy. To identify ESC in the subcultured ESC-like cell colonies, alkaline phosphatase activity and Oct-4 (octamer-binding transcription factor-4) expression were examined by immunohistochemistry and RT-PCR, respectively. To examine the spontaneous differentiation, ESC-like cell colonies were cultured without STO feeder cell layer and leukemia inhibitory factor (LIF). Results: Seven ESC-like cell lines were established from ICMs isolated from the in vitro fertilized embryos. According to the developmental stage, the growth of ICMs isolated from the expanded blastocysts was significantly better than that of ICMs isolated from the hatched blastocysts (80.3% vs. 58.7%, p<0.05). ESC-like cell colonies were only obtained from ICMs of expanded blastocysts. However, the ICMs isolated from the embryos treated with immunosurgery were poorly grown and frequently differentiated during the culture process. The established ESC-like cell colonies were positively stained with alkaline phosphatase and expressed Oct-4, and their morphology resembled that observed in the previously reported mouse ESC. In addition, following the extended in vitro culture process, they maintained their expression of cell surface markers characteristic of the pluripotent stem cells such as alkaline phosphatase and Oct-4. When cultured without STO feeder cell layer and LIF, they were spontaneously differentiated into the various types of cells. Conclusion: The findings of this study suggest that the establishment of mouse ESC can be successfully derived from the in vitro fertilized embryos. The established ESC-like cells expressed the cell surface markers characteristic of the pluripotent stem cells and spontaneously differentiated into the various types of cells.

소규모 기업에 있어서 지식소싱 전략이 기업성과에 미치는 영향 고찰 (An Examination of Knowledge Sourcing Strategies Effects on Corporate Performance in Small Enterprises)

  • 최병구
    • Asia pacific journal of information systems
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    • 제18권4호
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    • pp.57-81
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    • 2008
  • Knowledge is an essential strategic weapon for sustaining competitive advantage and is the key determinant for organizational growth. When knowledge is shared and disseminated throughout the organization, it increases an organization's value by providing the ability to respond to new and unusual situations. The growing importance of knowledge as a critical resource has forced executives to pay attention to their organizational knowledge. Organizations are increasingly undertaking knowledge management initiatives and making significant investments. Knowledge sourcing is considered as the first important step in effective knowledge management. Most firms continue to make an effort to realize the benefits of knowledge management by using various knowledge sources effectively. Appropriate knowledge sourcing strategies enable organizations to create, acquire, and access knowledge in a timely manner by reducing search and transfer costs, which result in better firm performance. In response, the knowledge management literature has devoted substantial attention to the analysis of knowledge sourcing strategies. Many studies have categorized knowledge sourcing strategies into intemal- and external-oriented. Internal-oriented sourcing strategy attempts to increase firm performance by integrating knowledge within the boundary of the firm. On the contrary, external-oriented strategy attempts to bring knowledge in from outside sources via either acquisition or imitation, and then to transfer that knowledge across to the organization. However, the extant literature on knowledge sourcing strategies focuses primarily on large organizations. Although many studies have clearly highlighted major differences between large and small firms and the need to adopt different strategies for different firm sizes, scant attention has been given to analyzing how knowledge sourcing strategies affect firm performance in small firms and what are the differences between small and large firms in the patterns of knowledge sourcing strategies adoption. This study attempts to advance the current literature by examining the impact of knowledge sourcing strategies on small firm performance from a holistic perspective. By drawing on knowledge based theory from organization science and complementarity theory from the economics literature, this paper is motivated by the following questions: (1) what are the adoption patterns of different knowledge sourcing strategies in small firms (i,e., what sourcing strategies should be adopted and which sourcing strategies work well together in small firms)?; and (2) what are the performance implications of these adoption patterns? In order to answer the questions, this study developed three hypotheses. First hypothesis based on knowledge based theory is that internal-oriented knowledge sourcing is positively associated with small firm performance. Second hypothesis developed on the basis of knowledge based theory is that external-oriented knowledge sourcing is positively associated with small firm performance. The third one based on complementarity theory is that pursuing both internal- and external-oriented knowledge sourcing simultaneously is negatively or less positively associated with small firm performance. As a sampling frame, 700 firms were identified from the Annual Corporation Report in Korea. Survey questionnaires were mailed to owners or executives who were most erudite about the firm s knowledge sourcing strategies and performance. A total of 188 companies replied, yielding a response rate of 26.8%. Due to incomplete data, 12 responses were eliminated, leaving 176 responses for the final analysis. Since all independent variables were measured using continuous variables, supermodularity function was used to test the hypotheses based on the cross partial derivative of payoff function. The results indicated no significant impact of internal-oriented sourcing strategies while positive impact of external-oriented sourcing strategy on small firm performance. This intriguing result could be explained on the basis of various resource and capital constraints of small firms. Small firms typically have restricted financial and human resources. They do not have enough assets to always develop knowledge internally. Another possible explanation is competency traps or core rigidities. Building up a knowledge base based on internal knowledge creates core competences, but at the same time, excessive internal focused knowledge exploration leads to behaviors blind to other knowledge. Interestingly, this study found that Internal- and external-oriented knowledge sourcing strategies had a substitutive relationship, which was inconsistent with previous studies that suggested complementary relationship between them. This result might be explained using organizational identification theory. Internal organizational members may perceive external knowledge as a threat, and tend to ignore knowledge from external sources because they prefer to maintain their own knowledge, legitimacy, and homogeneous attitudes. Therefore, integrating knowledge from internal and external sources might not be effective, resulting in failure of improvements of firm performance. Another possible explanation is small firms resource and capital constraints and lack of management expertise and absorptive capacity. Although the integration of different knowledge sources is critical, high levels of knowledge sourcing in many areas are quite expensive and so are often unrealistic for small enterprises. This study provides several implications for research as well as practice. First this study extends the existing knowledge by examining the substitutability (and complementarity) of knowledge sourcing strategies. Most prior studies have tended to investigate the independent effects of these strategies on performance without considering their combined impacts. Furthermore, this study tests complementarity based on the productivity approach that has been considered as a definitive test method for complementarity. Second, this study sheds new light on knowledge management research by identifying the relationship between knowledge sourcing strategies and small firm performance. Most current literature has insisted complementary relationship between knowledge sourcing strategies on the basis of data from large firms. Contrary to the conventional wisdom, this study identifies substitutive relationship between knowledge sourcing strategies using data from small firms. Third, implications for practice highlight that managers of small firms should focus on knowledge sourcing from external-oriented strategies. Moreover, adoption of both sourcing strategies simultaneousiy impedes small firm performance.

The Comparison of Basic Science Research Capacity of OECD Countries

  • Lim, Yang-Taek;Song, Choong-Han
    • 기술혁신연구
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    • 제11권1호
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    • pp.147-176
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    • 2003
  • This Paper Presents a new measurement technique to derive the level of BSRC (Basic Science and Research Capacity) index by use of the factor analysis which is extended with the assumption of the standard normal probability distribution of the selected explanatory variables. The new measurement method is used to forecast the gap of Korea's BSRC level compared with those of major OECD countries in terms of time lag and to make their international comparison during the time period of 1981∼1999, based on the assumption that the BSRC progress function of each country takes the form of the logistic curve. The US BSRC index is estimated to be 0.9878 in 1981, 0.9996 in 1990 and 0.99991 in 1999, taking the 1st place. The US BSRC level has been consistently the top among the 16 selected variables, followed by Japan, Germany, France and the United Kingdom, in order. Korea's BSRC is estimated to be 0.2293 in 1981, taking the lowest place among the 16 OECD countries. However, Korea's BSRC indices are estimated to have been increased to 0.3216 (in 1990) and 0.44652 (in 1999) respectively, taking 10th place. Meanwhile, Korea's BSRC level in 1999 (0.44652) is estimated to reach those of the US and Japan in 2233 and 2101, respectively. This means that Korea falls 234 years behind USA and 102 years behind Japan, respectively. Korea is also estimated to lag 34 years behind Germany, 16 years behind France and the UK, 15 years behind Sweden, 11 years behind Canada, 7 years behind Finland, and 5 years behind the Netherlands. For the period of 1981∼1999, the BSRC development speed of the US is estimated to be 0.29700. Its rank is the top among the selected OECD countries, followed by Japan (0.12800), Korea (0.04443), and Germany (0.04029). the US BSRC development speed (0.2970) is estimated to be 2.3 times higher than that of Japan (0.1280), and 6.7 times higher than that of Korea. German BSRC development speed (0.04029) is estimated to be fastest in Europe, but it is 7.4 times slower than that of the US. The estimated BSRC development speeds of Belgium, Finland, Italy, Denmark and the UK stand between 0.01 and 0.02, which are very slow. Particularly, the BSRC development speed of Spain is estimated to be minus 0.0065, staying at the almost same level of BSRC over time (1981 ∼ 1999). Since Korea shows BSRC development speed much slower than those of the US and Japan but relative]y faster than those of other countries, the gaps in BSRC level between Korea and the other countries may get considerably narrower or even Korea will surpass possibly several countries in BSRC level, as time goes by. Korea's BSRC level had taken 10th place till 1993. However, it is estimated to be 6th place in 2010 by catching up the UK, Sweden, Finland and Holland, and 4th place in 2020 by catching up France and Canada. The empirical results are consistent with OECD (2001a)'s computation that Korea had the highest R&D expenditures growth during 1991∼1999 among all OECD countries ; and the value-added of ICT industries in total business sectors value added is 12% in Korea, but only 8% in Japan. And OECD (2001b) observed that Korea, together with the US, Sweden, and Finland, are already the four most knowledge-based countries. Hence, the rank of the knowledge-based country was measured by investment in knowledge which is defined as public and private spending on higher education, expenditures on R&D and investment in software.

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무심천 수질 오염 실태와 그 방지책;I. 하계절의 수질 오염 분석 (Contamination of the Mushim-Cheon and its Countermeasures;I. Analysis of the Water Samples in Summer)

  • 이재구;경기성;김학남;오경석
    • 한국환경농학회지
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    • 제9권1호
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    • pp.23-37
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    • 1990
  • 무심천의 오염실태와 그 방지책을 강구하기 위하여 1989년 8월과 9월 2회에 걸쳐 채수한 수질을 분석하여 다음과 같은 결과를 얻었다. 1. 8, 9월의 주간 무심천 수온은 미생물과 조류의 생육에 지장이 없는 것으로 보이는25.8-$30.8^{\circ}C$로써 자정능력이 있는 것으로 판단되었다. 2. 동 기간중 무심천수의 pH는 St 14를 제외하고는 6.5-8.5 범위이었다. 3. St 18(분뇨처리장 배수구와 무심천의 합류지점)에서 9월에 DO가 0.7 ppm까지 내려가는 현상이 관찰되었다. 4. St 18에서 BOD가 최고 62.1 ppm으로써 분뇨 처리장 방류수의 BOD 허용치인 40 ppm 을 크게 초과하였다. 또한 SS도 8, 9월에 각각 200과 520ppm으로써 허용치인 70 ppm을 3-7배 초과 하였다. 5. St 18에서 9월중에 $NH_3-N$이 46.2 ppm이나 되는 것은 분뇨로 크게 오염되어 있음을 말해 준다. 6. 9월중 사직동 하수의 BOD 부하량은 약 0.306ton/day이었다. 7. 무심천 본류보다 무심천으로 유입되는 지천과 가정하수구 및 분뇨처리장 방류수에서 오염도가 훨씬 높았다. 8. St 12(사직동 하수)의 2시간별로 채수한 시료에서 오염물질의 부하량이 인근 주민의 생활주기와 밀접한 관계가 있음을 알 수 있었다. 9. 1979년 무심천 수질 분석 결과와 비교해 볼 때 영운동 취수장(St 9)에서는 큰 차이가 없었으나 사직동 하수(청주대교 밑, St 12)와 제2운천교(St 15)에서는 최근 10년 동안 수질이 더욱 악화되었음을 알 수 있다.

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밭에서 음식물류폐기물 활용 퇴비의 연용이 토양 및 작물에 미치는 영향 (The continuous application effect of the food waste composts on the cultivated upland soils and plants)

  • 권순익;소규호;홍승길;김건엽;성기석;박우균;김권래;이덕배;정광용
    • 유기물자원화
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    • 제17권3호
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    • pp.71-81
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    • 2009
  • 음식물류폐기물의 재활용은 환경오염 예방과 자원 순환이라는 목적을 가지고 활발하게 시도되고 있다. 본 연구는 음식물류폐기물을 활용한 퇴비의 안전한 농업적 활용 방안을 모색하고, 음식물류폐기물의 농업적 활용기준 설정을 위한 기초자료를 얻고자 수행하였다. 이를 위해서 음식물류폐기물 활용 퇴비의 장기간 연용이 작물 생육과 토양환경에 미치는 영향을 조사하였다. 시험에 사용된 재료는 질소, 인산, 칼리의 함량이 각각 $24g\;kg^{-1}$, $8g\;kg^{-1}$, $10.4g\;kg^{-1}$인 돈분퇴비와 질소, 인산, 칼리의 함량이 각각 $20g\;kg^{-1}$, $20.1g\;kg^{-1}$, $6.5g\;kg^{-1}$인 음식물류폐기물 활용 퇴비로써 $2{\times}2{\times}2m$ 크기의 라이시미터에 화학비료의 질소 시용량과 동일하게 시용한 후 상추, 배추, 고추 및 감자를 연속하여 재배 실험하였다. 음식물류폐기물 활용 퇴비를 시용한 시험구의 작물 생육은 무비구 보다는 양호하였으나 화학 비료구와 비교했을 때 작물에 따라 반응이 달랐다. 음식물류폐기물을 활용한 퇴비의 연속적인 시용은 토양의 이화학성에 대해서는 유기물, 질소 및 인산의 함량을 증가시켰고, 토양 물리성에 대해서는 통기성을 증가시켰다.

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K-REITs(부동산투자회사)의 투자 유형별 특성 분석 (A Study on the K-REITs of Characteristic Analysis by Investment Type)

  • 김상진;이명훈
    • 한국산학기술학회논문지
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    • 제17권11호
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    • pp.66-79
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    • 2016
  • 최근 리츠 인가의 증가로 대두되는 사안은 경영활동에 드는 자금을 어떻게 조달하는지와 투자 자금을 효율성 있게 운용함으로써 기대 수익률과 경영 극대화를 목표 설정에 맞게 실현될 수 있는지 대한 문제로 귀결되는 듯하다. 이에 본 연구는 국내 리츠가 운용된 2002년부터 2015년(2007~2009년, 글로벌 금융위기 기간의 파급효과 기간은 제외하였음)까지 리츠의 사업현황, 투자, 재무 등 경영 전반에 관련 자료를 구축하여 투자 유형별 특성을 분석하고 리츠의 부채비율에 영향을 미치는 요인을 분석하였다. 분석결과 리츠의 최대주주 성향이 법인, 연기금, 공제회, 은행, 증권, 보험 등의 비중이 높게 나타나며 최근 최대주주와 주요주주의 비중이 상승하고 있다. 리츠 투자에서 기관투자자 역할이 증대되면서 기관투자자가 리츠성장을 견인한 것으로 보인다. 기관투자자에서 자주 목격되는 동시 투자자에게 다른 금융기관보다 더 높은 이자율을 지급된 것으로 분석되어, 리츠가 동시투자자에 대하여 유인과 보상을 병행한 것으로 판단된다. 부채비율과 관련 변수 간의 영향요인에 대하여 다중회귀분석을 수행한 결과 부채비율이 수익성과는 음(-)의 관계를 맺어 자본조달순위이론을 지지하며, 투자기회(성장성)는 음(-)의 관계, 자산 규모와는 양(+)의 관계를 맺어 상충이론을 따르는 것으로 분석되었다. 이와 같은 연구결과는 국내 리츠가 공모형 리츠보다는 사모형 리츠 위주로 운용되고 있어 타인자본 조달 시 주식시장의 자금조달보다는 유형자산(대부분 부동산)의 담보에 의한 차입으로 운영되고 있는 리츠시장을 반영한 것으로 보인다. 또한, 글로벌 금융위기 이후 타인자본을 리츠 사업에 적극적으로 활용하고 있으며, 최대주주의 비중과 성향, 투자상품에 따라 부채비율이 결정되고 있음을 보여준다.

스퍼터링 증확 CdTe 박막의 두께 불균일 현상 개선을 위한 화학적기계적연마 공정 적용 및 광특성 향상 (Application of CMP Process to Improving Thickness-Uniformity of Sputtering-deposited CdTe Thin Film for Improvement of Optical Properties)

  • 박주선;임채현;류승한;명국도;김남훈;이우선
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2010년도 하계학술대회 논문집
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    • pp.375-375
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    • 2010
  • CdTe as an absorber material is widely used in thin film solar cells with the heterostructure due to its almost ideal band gap energy of 1.45 eV, high photovoltaic conversion efficiency, low cost and stable performance. The deposition methods and preparation conditions for the fabrication of CdTe are very important for the achievement of high solar cell conversion efficiency. There are some rearranged reports about the deposition methods available for the preparation of CdTe thin films such as close spaced sublimation (CSS), physical vapor deposition (PVD), vacuum evaporation, vapor transport deposition (VTD), closed space vapor transport, electrodeposition, screen printing, spray pyrolysis, metalorganic chemical vapor deposition (MOCVD), and RF sputtering. The RF sputtering method for the preparation of CdTe thin films has important advantages in that the thin films can be prepared at low growth temperatures with large-area deposition suitable for mass-production. The authors reported that the optical and electrical properties of CdTe thin film were closely connected by the thickness-uniformity of the film in the previous study [1], which means that the better optical absorbance and the higher carrier concentration could be obtained in the better condition of thickness-uniformity for CdTe thin film. The thickness-uniformity could be controlled and improved by the some process parameters such as vacuum level and RF power in the sputtering process of CdTe thin films. However, there is a limitation to improve the thickness-uniformity only in the preparation process [1]. So it is necessary to introduce the external or additional method for improving the thickness-uniformity of CdTe thin film because the cell size of thin film solar cell will be enlarged. Therefore, the authors firstly applied the chemical mechanical polishing (CMP) process to improving the thickness-uniformity of CdTe thin films with a G&P POLI-450 CMP polisher [2]. CMP process is the most important process in semiconductor manufacturing processes in order to planarize the surface of the wafer even over 300 mm and to form the copper interconnects with damascene process. Some important CMP characteristics for CdTe were obtained including removal rate (RR), WIWNU%, RMS roughness, and peak-to-valley roughness [2]. With these important results, the CMP process for CdTe thin films was performed to improve the thickness-uniformity of the sputtering-deposited CdTe thin film which had the worst two thickness-uniformities of them. Some optical properties including optical transmittance and absorbance of the CdTe thin films were measured by using a UV-Visible spectrophotometer (Varian Techtron, Cary500scan) in the range of 400 - 800 nm. After CMP process, the thickness-uniformities became better than that of the best condition in the previous sputtering process of CdTe thin films. Consequently, the optical properties were directly affected by the thickness-uniformity of CdTe thin film. The absorbance of CdTe thin films was improved although the thickness of CdTe thin film was not changed.

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형질전환 비만모델 수컷 hGHTg rats에서 경신해지환(輕身解脂丸)이 혈중 항비만지표에 미치는 영향 (The effects GeongshinhaeGihwan 1(GGT1) has on the hGHTg (human growth hormone transgenic) obese male rats' blood-antiobestic index)

  • 정양삼;총배금;최승배;김경철;신순식
    • 대한한의학방제학회지
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    • 제13권2호
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    • pp.1-16
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    • 2005
  • Objectives: To find out the effects GGTl, an antiobestic drug widely used in clinics, has on the blood-antiobestic index and the toxicity index using the data from the hGHTg obese male rats. We looked closely into both of the two indices because GGTl antiobestic effect can happen not only by pharmacological action, but also by its toxicity. Also, we verified the difference in effect between GGTl and reductil (sibutramine), which has been approved by the FDA of the United States. Methods: After performing the experiments for 8 weeks on the hGHTg obese male rats divided into three groups: the control group, the GGTl group, and the reductil (RD) group, we anesthetized the rats with Diethyl ether and took a 3ml blood sample from the heart. Then, after coagulating the blood in room temperature by using the plasma separator, we centrifuged it for 25 minutes in 3,000rpm using the high-speed refrigerated centrifuge. We kept the separated plasma in a deep freezer at $-80^{\circ}C$, and repeatedly measured the antiobestic index and the toxicity index twice using the hematology biochemistry analyzer. Also, in order to judge the indirect toxicity index, we separated liver from kidney and observed them. Results: When we looked at the results of the analysis of covariance on the measuring elements related to the antiobestic index (TC, HDL, LDL, TG, and GLU), there was no significant difference among the groups in all measuring elements. Also, the results of the analysis of covariance on the two roups (RD group and GGTl group) showed that the p-values had no significant difference under the level of significance 0.05. When we looked at the result of the analysis of covariance on the measuring elements related to the toxicity index (GOT, GPT, GGT, CREA, UA, ALB, and TP), we could see that the p-values in GPT, ALB, and TP have a significant difference among the groups. Also, the results of the analysis of covariance about the measuring elements related to the toxicity index on both groups, RD group and GGTl group, showed no significant difference in the p-values of all of the measuring elements in the two groups, RD and GGTl group. Conclusions: In conclusion, through this experiment, the safety of GGTl has been approved, and although the verification on its medical effect has not been clearly approved, when we consider the fact that it belongs to the same group as reductil, an antiobestic drug approved by the FDA of the United States, we could indirectly verify that GGTl has an antiobestic effect. We believe that when doing a sample design for a future experiment, it needs to be performed on a greater sample size based on the power analysis that needs to be performed primarily in experiments, and a more accurate verification is needed through more systematic experiment plans.

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한국 특산식물 변산바람꽃 자생지의 환경 특성과 식생 (Environmental Characteristics and Vegetation of the Natural Habitats of Korean Endemic Plant Eranthis byunsanensis B.Y. Sun)

  • 김현지;정혜란;구자정;최경;박광우;조도순
    • 환경생물
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    • 제30권2호
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    • pp.90-97
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    • 2012
  • 본 연구는 한국 특산식물인 변산바람꽃(Eranthis byunsanensis B.Y. Sun)의 분포현황 및 서식지에 대한 생태적 특성과 식생에 대해 조사하고 분석함으로써 향후 자생식물을 활용한 자원화 및 보전과 복원의 기초 자료로 활용하고자 수행되었다. 조사는 2010년 2월부터 7월까지 변산, 여수, 거제, 울산, 경주, 제주, 안양 등 7개 지역에서 수행되었다. 각 지역에 $1m{\times}1m$의 방형구를 총 59개 설치하고 방형구 내에 분포하는 모든 종의 피도와 빈도를 기록하였고, 상층부 교목의 우점종을 기록하고 서식지의 환경특성을 조사하였다. 조사 결과 변산바람꽃은 해발 84m~585 m 사이에 분포하였고, 총 59개 방형구 중 43개의 방형구가 북동사면에 위치하였다. 또한 경사 $10{\sim}20^{\circ}$의 계곡을 따라 불연속적으로 분포하였으며 토양분석결과 유기물은 평균 9.6%, pH는 4.9로 대부분 약산성이며 토양수분함량은 평균 16.5%로 나타났다. 고도에 대해 경사는 음의 상관관계를 보여 고도가 낮아질수록 경사가 완만해지며, 토양은 산성을 띄는 경향을 보였다. pH와 토양수분 함량, 변산바람꽃의 분포와 유기물은 정의 상관관계를 보여 수분이 풍부하고, 영양분의 공급이 원활한 지역을 선호하는 것으로 나타났다. 총 59개 방형구에서 144개 분류군이 나타났으며 서식지 주변의 교목으로서 고로쇠나무와 까치박달나무, 비목나무, 서어나무 등이 높은 빈도로 출현하였다. 이 연구 결과는 한국 특산식물인 변산바람꽃의 자생지 보전 및 복원의 자료로 활용할 수 있을 것이며, 변산바람꽃을 활용한 분화용 소재개발 및 재배 시 최적의 서식환경에 대한 정보를 제공할 수 있을 것으로 판단된다.