• Genomics & Informatics
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• v.12 no.4
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• pp.136-144
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• 2014

Besides single-nucleotide variants in the human genome, large-scale genomic variants, such as copy number variations (CNVs), are being increasingly discovered as a genetic source of human diversity and the pathogenic factors of diseases. Recent experimental findings have shed light on the links between different genome architectures and CNV mutagenesis. In this review, we summarize various genomic features and discuss their contributions to CNV formation. Genomic repeats, including both low-copy and high-copy repeats, play important roles in CNV instability, which was initially known as DNA recombination events. Furthermore, it has been found that human genomic repeats can also induce DNA replication errors and consequently result in CNV mutations. Some recent studies showed that DNA replication timing, which reflects the high-order information of genomic organization, is involved in human CNV mutations. Our review highlights that genome architecture, from DNA sequence to high-order genomic organization, is an important molecular factor in CNV mutagenesis and human genomic instability.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.3
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• pp.1722-1737
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• 2019

We developed an insider threat detection model to be used by organizations that repeat tasks at regular intervals. The model identifies the best combination of different feature selection algorithms, unsupervised learning algorithms, and standard scores. We derive a model specifically optimized for the organization by evaluating each combination in terms of accuracy, AUC (Area Under the Curve), and TPR (True Positive Rate). In order to validate this model, a four-year log was applied to the system handling sensitive information from public institutions. In the research target system, the user log was analyzed monthly based on the fact that the business process is processed at a cycle of one year, and the roles are determined for each person in charge. In order to classify the behavior of a user as abnormal, the standard scores of each organization were calculated and classified as abnormal when they exceeded certain thresholds. Using this method, we proposed an optimized model for the organization and verified it.

• Educational Technology International
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• v.9 no.2
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• pp.143-164
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• 2008

The purpose of this study was to find the existential meanings of the culturally marginalized community organization. Based on the findings, the study examined the issues related to operating the organization and found the ways of helping such organization through service learning programs. For the study, the researcher chose the Korean school of Knoxville in the USA as a service community organization. This study used a qualitative method using narrative construction in the nature of the text shapes with first-person point of views. The research findings were discussed based on the observations and participation in the organization. The study found that the Korean school plays a role as a cultural liaison connecting the Korean culture to other cultures while enabling students to critically accept their native systems, values, and customs through understanding of their native language. However, problems were found in operating the school due to the lack of skills and knowledge of the school administration. Suggestions were made and implemented to the school in order to improve the performance of the school.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.11a
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• pp.382.1-382
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• 2002

This paper presents a new approach integrated Case-Based Reasoning with Self- Organization Map(SOM) in diagnosis systems. The causes of faults are obtained by case-base trained from SOM. When the vibration problem of rotating machinery occurs, this provides an exact diagnosis method that shows the fault cause of vibration problem. In order to verify the performance of algorithm, we applied it to diagnose the fault cause of the electric motor.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2008.05a
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• pp.46-49
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• 2008

This research does Complexity form, Interior epidermis cell re-organization, Object discovery that have correct numerical value concept by purpose. Research applied by Grid re-organization in form generation, Parameter variation of cell unit (morphor, tweener), Symbol, pattern of variation, self-organization cell substitution order. Representation through 3d digital modeler of polygon, Nurbs and street-sheet program(x,y,z coordinates & Network way of points) etc. of main work. Investigator specified numbers of U profiles*30, V point-20 that is 600 Paramaters individual in volume, and define circle radius of lighting in object, Projection size variously and tried difference. Transposition cell to point and Heightened brightness of color using pointillism of painting. Led lighting cell object is expressed being decoded by digital code.

• Journal of Fisheries and Marine Sciences Education
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• v.26 no.2
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• pp.382-391
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• 2014

The purpose of this study was to confirm the relationship between teacher's resilience and job satisfaction and observe the mediating effect of organization in the relationship. For the study, a survey about resilience, job satisfaction, and organization was conducted on 913 elementary, middle, and high school teachers working at Busan and Ulsan. The result was statistically treated using SPSS 18.0 program. The results of this study are as follows: First, there were as positive relationships among teacher's resilience, job satisfaction, and organization. Second, the mediating effect of organization in the relationship between teacher's resilience and job satisfaction was shown by the partial mediating effect. The result of the study shows that teacher's resilience is the variables influencing job satisfaction but organization is more important variables. Therefore, it suggests to establish organizational ethical climate for active communication among school members in order to improve teacher's job satisfaction.

• Journal of Korean Academy of Nursing Administration
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• v.9 no.1
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• pp.75-88
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• 2003

Purpose : The Purposes of this study was to develop a learning organization measurement for nurses, and to test the validity and reliability of the measurement. Method : This study was conducted through 3 phases -theoretical framework choice, measurement items selection, and the testing of validity and reliability. In order to test reliability and validity of the measurement, data were collected from the 261 nurses, working in the 1 hospital with more 800 beds. The data obtained were analyzed by SPSS for Window program using percentages, Factor Analysis, Cronbach's alpha coefficients. Result : As a result of the study, 2 scales -Learning Organization Building Scale, and Knowledge Management Process Scale- were developed. Learning Organization Building Scale was consisted of 23 items, 5 factors. 5 factors explained 60.26% of the total variance, and the Cronbach's alpha of this scale was .8807. Knowledge Management Process Scale was consisted of 17 items, 4 factors. 4 factors explained 66.14% of the total variance, and the Cronbach's alpha of this scale was .9147. Conclusion : The Study supports the validity and reliability of the scales. Therefore, these scales can be effectively utilized for many researches about Learning organization of Nurse, and Nursing organization in the Hospital Setting.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.43 no.4
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• pp.84-92
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• 2020

In order to analyze the organizational performance of government-funded research institutes, four independent variables (organization size, organization age, evaluation system, organization location) and goal ambiguity were empirically analyzed. Although there are existing studies on institutional evaluation, which is the organizational performance of government-funded research institutes, there are differences in research in that it is an empirical analysis analyzed from the perspective of goal ambiguity and that the evaluation system, which is the specificity of institutional evaluation, is included in the analysis. As a result of the analysis, organizational location was the only independent variable that had a direct significant effect on organizational performance, and goal ambiguity showed a significant mediating effect for all independent variables. This indicates that goal ambiguity plays an important role in the organizational performance of government-funded research institutes, and to reduce this, increase the size of the organization, pay attention to establishment of the organization for organizational age, and that it is desirable to have an independent research group in the government department for the organization location. In addition, it was supported that the improvement effect of the evaluation system is proceeding in a desirable direction in terms of goal ambiguity.

• Journal of Korean Academy of Nursing Administration
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• v.12 no.1
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• pp.151-158
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• 2006

Purpose: This study was undertaken in order to suggest self-leadership as a way to promote organization efficiency of nursing organization. So the relation between self-leadership and outcome of nursing practice in organization was studied. Method: The subjects of study were nurses as a population who were working for the 2 of university hospitals which have over 500 beds in Kyong Ki Province as well as who have been working for over 6 months. The data was collected by questionnaires from 215 nurses and analyzed using descriptive statistics, perason correlation coefficient, t-test and ANOVA on SAS Program. Results: Self-leadership of nurse got 3.51 grade out of 5 as a mean point. Each of the segments got 3.74 in self-compensation, 3.57 in self-expectation, 3.53 in goal-setting, 3.45 in rehearsal, 3.37 in self-criticism and 3.30 in constructive thinking in order. Independent performance of nursing practice at each items of outcome of nursing practice showed the highest correlations with the self-expectation among self-leadership segments. Constructive thinking, self-compensation, rehearsal, goal-setting were related like this in order, but self-criticism was related just a little. Dependent nursing practice has the highest correlation with the self-expectation, goal-setting, rehearsal, constructive thinking, self-compensation were similar as aboves in order, but self-criticism didn't show any similar correlations. Relationship practice has the highest correlation with the self-expectation, and goal-setting, constructive thinking, self-compensation, rehearsal were similar, while self-criticism did not show any correlations. Conclusion: In conclusion the result was obtained that self-leadership is much correlated with outcome of nursing practice. Therefore, as a way to promote efficiency of nursing organization, the constant study about self-leadership with the various aspects is needed focusing on self-management and inner motivation as a new leadership paradigm.

• The Korean Journal of Health Service Management
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• v.8 no.3
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• pp.1-11
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• 2014

The present study aimed to survey doctors working in five university hospitals about internal customer satisfaction and organization commitment level in order to identify casual relationships through structure equations. According to the analysis, organization management had the biggest impact on internal customer satisfaction level, and the sooner the factor was named personnel, leadership, job, and compensation, the bigger the impact it had on the level. The research model was generally found to be good in terms of goodness of fit, considering the value of $x^2$ calculated as 103.314, the degrees of freedom of 38, GFI 0.924, AGFT 0.868, NFI 0.888, CFI 0.925, and RMSEA 0.086. In conclusion, the internal customer satisfaction level of doctors was significantly proportionate to organization commitment by means of their general satisfaction level, while also being directly proportionate to organization commitment (p<0.05). Meanwhile, statistical significance could not be found when measuring the effects of the doctors' basic characteristics on the levels of internal customer satisfaction and general satisfaction in hospitals.