• Preventive Nutrition and Food Science
• /
• 제20권4호
• /
• pp.246-252
• /
• 2015

The hot water extract of leather carp (Cyprinus carpio nudus) has been used as a nourishing tonic soup and as an aid for recovery from physical fatigue. In this study, we investigated the effect of leather carp extract on exercise performance in mice. Swimming endurance and forelimb grip strength were assessed following oral administration of the extract (once per day for 7 days) at a dose of $0.5 mg/10{\mu}L/g$ body weight. After 7 days, mice given the leather carp extract had significantly greater swimming endurance [$105{\pm}18s$ (P<0.05); 52% longer than day 0] and forelimb grip strength [$1.18{\pm}0.05$ Newton (P<0.01); 17% greater than day 0]. The extract increased muscle mass, but had little effect on body weight. Following the swimming exercise, blood glucose, glutathione peroxidase, and superoxide dismutase levels in extract-fed mice were significantly higher (145%, 131%, and 106%, respectively) than in the saline control group. Blood levels of high-density lipoprotein cholesterol were also significantly increased (128%) in mice given the extract compared to the controls. These results suggest that leather carp extract can improve physical exercise performance and prevent oxidative stress caused by exhaustive workouts.

• Journal of Yeungnam Medical Science
• /
• 제16권1호
• /
• pp.34-42
• /
• 1999

고혈당과 고지질혈증이 운동 중 골격근의 당원절약효과가 있는지 또는 골격근섬유의 특생에 따른 차이가 있는지를 규명하기 위해서 흰쥐(Sprague Dawley)를 대상으로 실험한 연구결과를 요약하면 다음과 같다. 먼저 고혈당에 의한 결과는 하지근 중 족척근의 운동부하 45분군의 당원농도가 고혈당군에서 대조군의 그것보다 약 13% 높아서 고혈당에 의한 족척근의 당원절약효과를 관찰할 수 있었으며 또한 백색 비복근의 운동부하 45분군에서 절약효과를 관찰할 수 있었다. 그러나 서근인 가자미근과 서근의 특성이 강한 적색 비복근에서는 모든 실험군에서 5-13%의 절약경향이 있었다. 이때 고혈당군의 혈당농도는 운동부하 전, 운동부하 30 및 45분후에 각각 $145.7{\pm}7.4$, $164{\pm}6.2$ 및 $156{\pm}6.8mg/dL$로서 대조각군의 혈당농도보다 유익하게 높았다. 고지질혈증은 복강내 heparin투여와 10% 인트라리포즈를 경구 투여하여 유도하였으며 대조군, 대조운동부하군 및 고지질혈증군에서 유리지방산 농도(uEq/L)가 $247{\pm}41.1$, $260{\pm}58.6$ 및 $444{\pm}23.1$로서 고지질혈증군이 다른 양 군보다 유의하게 높았다. 고지질혈증에 의한 근당원절약효과가 있는지 여부를 관찰한 결과 가자미근, 적색 비복근 및 족척근 등에서 통계적으로 유의한 절약효과를 관찰할 수 없었으나 백색 비복근에서 절약의 경향을 보였다. 이상의 결과로 보아 흰쥐에서 비교적 단시간의 운동부하 중 평균 155mg/dL의 고혈당을 유지하였을 때 족척근과 백색 비복근에서 근 당원이 절약되었으며 고지질혈증에 의해서는 근당원의 절약효과가 없었다. 또한 속근섬유의 근육에서 고혈당에 의한 당원절약효과가 서근보다 뚜렷하였다.

• 음성과학
• /
• 제15권3호
• /
• pp.103-116
• /
• 2008

Cerebral palsy children represent abnormal vocalization pattern caused by respiration problem and paralyzed oral motor muscle that are the basics of speech production. Thus, this study examined the effect of respiration and articulator training programs on the basic ability of speech production in CP children. The subjects of this study were 4 children with 3 of spastic CP and 1 of ataxia CP. The respiration and articulator program was conducted in 30 sessions for 30 minutes each. Pre-test was administered twice before the program, ongoing test was administered every 5 session during the period of experiment, and post-test was administered twice. The program included speech production such as respiration training, lips, jaw, cheek, and tongue exercise, and velopharyngeal training, and related articulator training. The following results were obtained. First, all subject children were less than 5 seconds in maximum phonation time before the experiment and 2 were improved by more than 4$\sim$5 seconds during the experiment, but 2 had relatively low rising width. Second, while children with less than 30dB before the experiment became bigger in strength during the experiment, children with more than 35dB before the experiment showed a minor change. Subject child 4 had lower vocal strength in the post-test period. Finally, although each subject had individual difference in syllable diadochokinetic ability, the function was improved and the number of repetition in one respiration was also increased.

• Preventive Nutrition and Food Science
• /
• 제20권2호
• /
• pp.133-136
• /
• 2015

Freshwater softshell turtle (Trionyx sinensis) extract has been used traditionally as a tonic soup, and to recover from physical fatigue. To support these claims, the forelimb grip strength of mice was measured after feeding a soft-shell turtle extract for 7 days. The T. sinensis extract significantly increased the grip strength to $1.25{\pm}0.07N$ (P<0.01), which is 16.8% higher than the force on day 0. After exercising, the blood glucose levels in extract-fed mice were 202% higher and urea levels were 73% lower, which were both significantly different than the levels observed after control treatment. Lactate dehydrogenase was significantly higher by 314%, and glutathione peroxidase increased by 165%. In addition, the obesity markers, serum triglyceride and cholesterol, decreased to 62% and 49%, respectively, after mice were fed the extract. These data show that the T. sinensis extract provided more energy for forelimb exercise, prevented protein catabolism and muscle fatigue, and decreased the oxidative stress caused by an exhaustive workout.

• 근관절건강학회지
• /
• 제20권1호
• /
• pp.31-42
• /
• 2013

Purpose: The purpose of this study was to develop an evidence-based dysphagia nursing care protocol for nursing home (NH) residents in Korea. Methods: The protocol was developed based on international guidelines and literatures. After testing content validity by experts, the protocol was applied to the intervention group (n=35) for 4 weeks at one NH in December, 2011, whereas the control group (n=34) received routine care. Results: The protocol was composed of one-page algorithm and detailed guidelines. Algorithm pathway was organized in 3 parts, including screening dysphagia risk, grouping by dysphagia risk level, and assigning nursing care into each group. The nursing care included positioning, oral care, meal time care, diet modification, providing exercise and maneuver, and checking dysphagia signs and symptoms. The experts verified the content validity. Protocol was revised to fit NH practice after the participant observation. Clinical validity was established upon evaluating usefulness, appropriateness, and convenience of the protocol by NH nurses. Dysphagia risk of the intervention group was significantly decreased. Conclusion: Developed protocol will improve the quality of dysphagia care in nursing homes as it can serve as a consistent and integrated standard for nursing care of residents with dysphagia.

• Journal of Pharmaceutical Investigation
• /
• 제25권1호
• /
• pp.1-7
• /
• 1995

After oral administration of various drinking solutions, the initial absorption rate of water through gastrointestinal tract of the rabbits was evaluated using tritinated water $(^3H_2O)$ as a marker to develop the sports drinking beverage for Korean people. The polynomial curve fitting over 20 min was performed using computer program to obtain the initial absorption rate of water from the tangent line of the fitted equation because initial absorption rate of water was more critical compared to elimination rate during exercise. The amount of water absorbed was increased but a large variation was observed among testing preparations in a small study group $(2{\leq}n{\leq}6)$. The initial absorption rate of water from isotonic sports drinking beverages was statistically significant when compared to hypertonic cola but was not significant when compared to hypotonic solutions (potable water and barley water). In case of hypertonic sports dringking beverages (i.e. Takeda), initial absorption rate of water was not improved and efficient when compared to other isotonic sports dringking beverages. The initial absorption rate of water from prescribed isotonic sample solution containing electrolytes, carbohydrates, and vitamins was not statistically significant when compared to other isotonic drinking beverages but showed similar absorption profile. It was obvious that isotonic solutions simultaneously containing electrolytes, vitamins and carbohydrates (sugar and glucose) had a tendency to increase the initial absorption of water compared to hypotonic (potable water and barley water) and hypertonic preparations (orange juice and cola). Although statistical significance of initial absorption rate of water between isotonic sports drinking beverages and hypotonic potable and barley water was not observed, unlike the hypertonic solutions, isotonic sports drinking beverages may aid not only to replenish loss of water, electrolytes and other nutrients during the exercise but also to prevent dehydration and muscle fatigue, resulting in improved physical performance in an exhausted condition.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제14권4호
• /
• pp.327-339
• /
• 1992

This study was undertaken to investigate the effect of orthognathic surgery on occlusal force. The maximum bite force was measured in 26 dentofacial deformity patients, aged 14-26(mean age 20.3) years, before surgery and at IMF removal, 3, 6, and 12months postsurgery. To grope the correlation of bite force and skeletal change after orthognathic surgery, the cephalometric headplates were measured, tabulated and statistically analyzed. The results were as follows. 1. The presurgical maximum bite force was 13.7kg in upper first molar(rt. Side 12.7kg, it. Side 14.6kg). There was remarkable difference with that of normal occlusion. 2. The recovery of bite force was very significant in according to the operation method and the duration of IMF that was 7.6kg at IMF removal, 14.2kg at 3 months, 19.7kg at 6 months. 26.1kg at 12 months postsurgery. 3. To fasten the recovery and to increase the bite force after orthognathic surgery, the long IMF time and the injury to the masticatory muscle should be avoided by the internal rigid fixation and early physical exercise. 4. The bite force was positively correlated to the changes of mandibular plane angle, the angle between platatal plane and mandibular plan, the angle between occlusal plane and mandibular plane, and negatively correlated to the changes of mandibular body length in craniofacial structure. 5. There was no correlationship between bit force and mesial inclination of tooth long axis of first molar in this subject. 6. There was no correlation between the changes of bite force and the changes of mechanical advantage of the temporal and masseter muscle.

• 대한소아치과학회지
• /
• 제32권2호
• /
• pp.256-261
• /
• 2005

피부 경화증(scleroderma)은 만성 결체조직 질환으로 정확한 원인은 밝혀지지 않았으나 자가 면역 질환으로 알려져 있다. 대개 $30{\sim}50$세의 여성에서 호발하며 소아에서는 매우 드물다. 장기의 이환여부에 따라 국소성과 전신성 피부 경화증으로 분류할 수 있다. 국소적 형태는 예후가 양호하고 피부에만, 또는 피하 근육까지 이환되며, 내부 장기에는 이환되지 않는다. 전신적인 형태는 피부와 구강점막 및 위장계, 호흡계, 심혈관계 등을 포함하늘 전신 다발적 발생 (multisystemic involvement)이 특징적이다. 안면피부 이환시 작고 예리한 코, 무표정한 응시 (expressionless stare), 좁아진 입모양(narrow oral aperture) 등이 특징적이다. 대개 레이노 현상(Raynaud's phenomenon)이 존재하며 질환이 진행되면서 개구장애와 혀, 치은의 경화가 나타나게 된다. 피부 석회증(calcinosis cutis), 레이노현상(Raynaud's phenomenon). 식도 기능부전(esophageal dysfunction), 공지증(sclerodactyly), 모세혈관 확장증(telangioectasia)이 복합된 질환을 크레스트 증후군(CREST syndrome)이라 부른다. 피부 경화증의 치료는 국소적 및 전신적 스테로이드 치료, collagen cross-link inhibitor (D-penicillamine), 면역억제제 등을 사용한다. 개구제한의 치료는 설압자를 이용한 mouth stretching exercise를 통해 개선될 수 있다. 본 증례에서는 국소성 피부 경화증으로 진단되고 개구제한이 있는 6세 남아에게 아산화질소와 enflurane을 이용한 깊은 진정요법을 이용하여 상하악 제 1, 2 유구치의 우식치료 치험례를 보고한다.

• Tuberculosis and Respiratory Diseases
• /
• 제50권2호
• /
• pp.245-251
• /
• 2001

저자들은 신장의 혈관근지방종을 동반한 폐임파관평활근종증 1예를 경험하였기에 폐임파관평활근종증에 대한 문헌고찰과 함께 보고하는 바이다.

• 구강회복응용과학지
• /
• 제29권1호
• /
• pp.101-110
• /
• 2013

T4K는 혼합치열기의 2급 부정교합 환자에게 사용되는 기능성, 가철성 교정장치이다. 기능성 교정장치의 경우 치열과 악골의 성장에 영향을 주는 구강안면부의 근육의 부조화를 개선시키는 역할을 한다. T4K에 포함된 lip bumper는 과도한 하순의 힘을 차단하여 주고, 하순 내측 전정을 자극하는 요소가 포함되어 있다. 부적절한 혀의 위치를 교정할 수 있는 요소는 환자들이 장치를 장착하는 동안 부가적인 혀 운동을 할 필요성을 감소시킨다. 2급 부정교합 환자의 경우 하악 열성장을 동반하는 경우가 대부분을 차지한다. 이 장치는 상악 치아를 고정원으로 하여, 하악을 전방으로 성장할 수 있도록 자극하여 부족한 하악 성장을 촉진하는 역할을 하고 있다. 이와 함께 부가적으로 Labial bow와 같은 역할을 하는 요소는 상악 치열의 개선에 도움을 준다. T4K는 기성품으로 작은 부피와 부드러운 질감으로 어린 환자들의 장착 동의율을 높이는 데 장점을 가진다. 원광대학교 치과대학 산본치과병원 소아치과에 내원한 혼합치열기의 2급 부정교합 환자에서 만족스러운 결과를 얻었기에 이를 보고하는 바이다. 요약 1. T4K를 혼합치열기의 2급 부정교합 환자에게 사용하여 안모의 개선을 얻었다. 2. 과도한 수직, 수평 피개교합이 개선되었다. 3. 하악 열성장 환자에서 T4K를 장착하여 하악 성장을 촉진하는 결과를 얻었다. 4. 구호흡 등과 같은 구강악습관의 개선을 얻었다.