• 제목/요약/키워드: Optimal mixture composition

검색결과 49건 처리시간 0.03초

혼합물 실험 계획법을 활용한 세정용 계면활성제 혼합물 조성의 최적화 (Optimization of Surfactant Mixture Composition for Cleansing Using Mixture Experiment Design)

  • 송마리아;진병석
    • 공업화학
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    • 제32권5호
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    • pp.574-580
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    • 2021
  • 최고 품질의 클렌징 제품 개발을 위해서 계면활성제 혼합물 조성의 최적화를 시도하였다. 사전실험을 통해 세정력, 기포형성력, 오염률에서 각각 우수한 특성을 나타내는 계면활성제 3종 sodium cocoyl alaninate (SCoA), cocamidopropyl betaine (CPB), decyl glucoside (DG)을 선정하였다. 계면활성제 혼합물의 심플렉스 중심 설계 배열에 따른 실험을 수행하고, 실험에서 얻어진 데이터를 가지고 회귀분석을 실시하였다. 통계적으로 유의미한 반응 표면 모델식을 구하고, 세 개의 반응변수의 동시 최적화 과정을 통해 계면활성제 혼합물의 최적 조성은 SCoA (0.22), CPB (0.78), DG (0.00)으로 구해졌다.

A Mixture of Curcumin, Vitamin C, and E Prolongs the Antioxidant Effect to Beyond That of Each Component Alone in Vivo

  • Jeon, Hee-Young;Kim, Jeong-Kee;Lee, Ji-Eun;Shin, Hyun-Jung;Lee, Sang-Jun
    • Food Science and Biotechnology
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    • 제17권6호
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    • pp.1151-1155
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    • 2008
  • This study aimed to investigate the alterations in plasma antioxidant activity after the consumption of a single oral dose of curcumin, vitamin C, and E administered individually or in combination to (i) assess possible synergies or antagonism between the antioxidants and (ii) determine the optimal composition of the antioxidant mixture such that the duration of action is prolonged to beyond that of individual antioxidants. Each antioxidant was administered to male Sprague-Dawley rats, and blood samples were drawn at different time points up to 180 min to measure the plasma total antioxidant capacity (TAC). Five antioxidant compositions (M1-M5) were evaluated to assess the possible synergies or antagonisms among them and to determine the optimal composition of the antioxidant mixture. Blood samples were collected up to 360 min post-consumption. A single oral dose of individual antioxidants significantly increased the TAC values; however, the time to reach the peak TAC value varied. Among the 5 antioxidant compositions, M2 exhibited the highest and most prolonged antioxidant effect in plasma; this was greater than the proportional sum of the effects of the individual antioxidants in the composition. This result indicates a synergistic interaction among antioxidants in the optimal composition M2.

합성목재의 난연성 확보를 위한 혼합물 실험계획 사례 (A Case Study of Applying Mixture Experimental Design to Enhance Flame Retardancy of Wood-Plastic Composites)

  • 서호진;권민서;이건명;주혜진;변재현
    • 품질경영학회지
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    • 제50권1호
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    • pp.169-181
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    • 2022
  • Purpose: This paper addresses a case study of developing a flame retardant wood-plastic composites (WPC) by adding tannic acid to the existing synthetic wood. The optimal mixing ratios of six components are explored to minimize the burning time using two mixture designs. Methods: In the preliminary experiment, six components are considered to find important components and their ranges. Seven D-optimal mixture design points are generated. Two points are removed for the balance of plastic components to be maintained, and the remaining five points are augmented with two basic compositions. Four components are selected to be considered in the main experiment. In the main experiment, pellets are extruded at the eight mixture design points. In-house testing of burning time is executed three times. Specimens made of pellets from two promising flame retardant compositions are sent to the accredited laboratories and tested. Results: The test results are as follows: 1) The best composition (Wood flour, Tannic acid, PE, Lubricant) = (25, 41, 10, 2) (wt%) shows the burning time of 1 second, which is 9-fold improvement compared to the the burning time of 9 seconds from the existing composition (58, 0, 10, 2) (wt%). 2) The second best composition (41, 25, 10, 2) (wt%) results in the burning time of 2 seconds. This composition is inferior to the best composition in terms of the flame retardancy, but more economical since it needs less tannic acid which is 100-fold expensive than the wood flour. Conclusion: Flame retardant compositions are found by adding tannic acid to the existing WPC employing optimal mixture designs. This case study will be helpful to practitioners who try to develop new products with additional physical properties with as small number of experimental trials as possible. Future research direction includes exploring conditions which satisfy both performance level and cost limitation simultaneously.

Influence of Electrolyte Composition on Electrochemical Performance of Li-S Cells

  • Kim, Tae Jeong;Jeong, Bo Ock;Koh, Jeong Yoon;Kim, Seok;Jung, Yongju
    • Bulletin of the Korean Chemical Society
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    • 제35권5호
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    • pp.1299-1304
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    • 2014
  • The electrochemical performance of Li-S cells was investigated in various ternary electrolyte solutions composed of 1,2-dimethoxyethane (DME), tetra(ethylene glycol) dimethyl ether (TGM), and 1,3-dioxolane (DOX). The discharge capacity values and cycle data obtained at each composition were statistically treated with the Minitab program to obtain mixture contour plots, from which the optimal composition of the ternary solvent systems was predicted. The discharge capacities and capacity retention were quite dependent on the electrolyte composition. It was estimated from the contour plots of the capacity at 1.0 C that the discharge capacity sharply increased with a decrease in the TGM content. High capacities greater than 900 mAh/g at 1.0 C were expected for the electrolyte composition with a volume ratio of DME/TGM/DOX = 1/0/1. In contrast, it was predicted from the mixture contour plot of the capacity retention that the cycle performance would significantly increase with an increase in the DME content.

혼합물계획법에 의한 Li2O-ZrO2-SiO2 유리의 이온전도도와 조성의 관계 (Relationship between Ionic Conductivity and Composition of Li2O-ZrO2-SiO2 Glasses Determined from Mixture Design)

  • 강은태;김명중;김재동
    • 한국세라믹학회지
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    • 제44권4호
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    • pp.219-223
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    • 2007
  • The ionic conductivity of $Li_2O-ZrO_2-SiO_2$ glasses has been designed and analyzed on the basis of a mixture design experiment with constraints. Fitted models for the activation energy and the ionic conductivity are as follows: $Q(kJ/moi)=54.8565x_1+144.825x_2+133.846x_3-170.908x_1x_3-334.338x_2x_3$ $log{\sigma}(300K)=-5.00245x_1-1.17876x_2-15.5173x_3+17.4522x_1x_3$. The electrical properties are very sensitive to the ratio of $Li_2O/SiO_2$. The effect of $ZrO_2$ is less than that of this ratio but $ZrO_2$ component attributes to the reduction of the activation energy. The optimal composition for best ionic conduction based on these fitted models is $55Li_2O{\cdot}10ZrO_2{\cdot}35SiO_2$. Its activation energy and ionic conductivity at 300 K are 46.98 kJ/mol and $1.08{\times}10^{-5}{\Omega}^{-1}{\cdot}cm^{-1}$, respectively.

Comparison of Three Commercial Collagen Mixtures: Quality Characteristics of Marinated Pork Loin Ham

  • Choe, Juhui;Kim, Hack-Youn
    • 한국축산식품학회지
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    • 제39권2호
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    • pp.345-353
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    • 2019
  • Various commercial collagen mixtures aimed at improving the quality of meat products are available, but the optimal composition is unclear. This study aimed to compare the functional properties, including physicochemical characteristics and lipid oxidative stability, of loin ham marinated with three commercial collagen mixtures sold as food additives. The addition of collagen mixtures led to significant increases in the moisture content, water holding capacity (WHC), cooking yield, and instrumental tenderness, regardless of the type of collagen mixture. In particular, meat samples containing collagen mixture C showed the highest (p<0.05) WHC and tenderness among all groups. Furthermore, collagen mixture B induced increases (p<0.05) in pH values in both raw and cooked samples. The $a^*$ values of samples with collagen mixtures were lower (p<0.05) than those of samples without collagen mixtures. All collagen mixtures effectively improved oxidative stability during 7 days of storage at $4^{\circ}C$. The samples containing collagen mixture B had the lowest lipid oxidation (p<0.05) among groups. These results indicated that collagen mixture C could be used in injection brine to enhance the quality characteristics of meat products, particularly the WHC and tenderness. Collagen mixture A could be used for meat products with high fat contents based on its ability to improve lipid oxidative stability during long-term storage.

Effects of Replacement of Concentrate Mixture by Broccoli Byproducts on Lactating Performance in Dairy Cows

  • Yi, X.W.;Yang, F.;Liu, J.X.;Wang, J.K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제28권10호
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    • pp.1449-1453
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    • 2015
  • The objective of the present study was to determine the effects of feeding pelletized broccoli byproducts (PBB) on milk yield and milk composition in dairy cows. In Trial 1, an in vitro gas test determined the optimal replacement level of PBB in a concentrate mixture in a mixed substrate with Chinese wild ryegrass hay (50:50, w/w) at levels of 0, 10%, 20%, 30%, or 40% (dry matter basis). When the concentrate was replaced by PBB at a level of 20%, no adverse effects were found on the gas volume or its rate constant during ruminal fermentation. In trial 2, 24 lactating cows (days in milk = $170.4{\pm}35$; milk yield = $30{\pm}3kg/d$; body weight = $580{\pm}13kg$) were divided into 12 blocks based on day in milk and milk yield and randomly allocated to two dietary treatments: a basic diet with or without PBB replacing 20% of the concentrate mixture. The feeding trial lasted for 56 days; the first week allowed for adaptation to the diet. The milk composition was analyzed once a week. No significant difference in milk yield was observed between the two groups (23.5 vs 24.2 kg). A significant increase was found in milk fat content in the PBB group (p<0.05). Inclusion of PBB did not affect milk protein, lactose, total solids or solids-not-fat (p>0.05). These results indicated that PBB could be included in dairy cattle diets at a suitable level to replace concentrate mixture without any adverse effects on dairy performance.

유증기 연소처리를 위한 난류 부분예혼합화염의 활용 및 유동장 가시화 (Utilization and Visualization of Turbulent Partially-premixed Flame for Combustion of Inert-gas-diluted VOC)

  • 안태국;남연우;박선호
    • 한국연소학회:학술대회논문집
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    • 한국연소학회 2015년도 제51회 KOSCO SYMPOSIUM 초록집
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    • pp.193-196
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    • 2015
  • Combustion of low concentration VOC in inert gas around the flammability limit has been experimentally studied. Streams of nitrogen and propane mixture with various compositions and flow conditions were treated by a turbulent partially-premixed pilot flame. HC and CO contents in exhaust gas measured and the flow patterns were visualized. The results suggested that there exists an optimal mixture velocity range for efficient combustion treatment for each flow condition and composition of the mixture.

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메탄올-아세톤 분리를 위한 압력 변환 증류 공정에서 환류를 통한 유입 조성 최적화 (Optimal feed compositon of pressure swing distillation system to separate methanol and acetone)

  • 윤영각;서승권;이철진
    • 플랜트 저널
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    • 제13권3호
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    • pp.26-29
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    • 2017
  • 본 연구에서는 메탄올-아세톤 압력 변환 증류 공정에서 유입 흐름의 조성 최적화를 진행하였다. 압력 변환 증류 공정에서 유입 흐름의 조성은 혼합물 분리가능성에 지대한 영향을 주는 것이 잘 알려져 있다. 분리된 순수한 물질의 환류흐름을 이용하여 유입 흐름의 조성을 조절하여 정해진 압력에서 보다 나은 분리효율을 보이는 것을 이번 연구의 목적으로 한다. 환류 흐름이 없는 압력 변환 증류 공정을 기본 공정으로 하여, 메탄올의 환류 흐름이 있는 경우와 아세톤의 환류 흐름이 있는 경우 두 가지 공정이 설계되었다. 각 공정은 Total annual cost로 비교되었으며, 그 결과 환류 흐름이 없는 기본 공정이 가장 유리한 것으로 나타났다.

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실험 계획법을 적용한 세라마이드 고함량의 수화 액정형 베시클의 최적설계 (Design Optimization of Hydrated Liquid Crystalline Vesicles Containing a High Content of Ceramide Using DOE)

  • 신주영;진병석
    • 한국응용과학기술학회지
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    • 제39권5호
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    • pp.623-631
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    • 2022
  • 실험 계획법을 활용하여 세라마이드가 고함량으로 함유된 수화 액정형 베시클의 입자 사이즈에 영향을 미치는 인자를 분석하고 혼합물 조성의 최적화를 시도하였다. 베시클 입자 사이즈에 영향을 주는 주요 변수로 제조 온도, 에탄올 양, 초음파 시간을 각각 정하고, 다구찌 방법의 S/N비 산출과 ANOVA 분석을 통해, 이들 변수들이 입자 사이즈에 미치는 영향을 살펴보았다. 또한 혼합물 실험 계획법의 심플렉스 중심 설계에 따라, 베시클 막을 구성하는 세 지질 성분, 인지질(HPC), 콜레스테롤(Chol), 세라마이드(Cer)의 혼합 조성 실험을 수행하였다. 실험에서 얻어진 데이터로부터 회귀분석을 실시하여 모델식을 구하고, 베시클 입자 사이즈를 최소로 만들기 위한 세 지질 성분의 최적 혼합 조성은 HPC(0.6), Chol(0.1), Cer(0.3)으로 구해졌다.