A Mixture of Curcumin, Vitamin C, and E Prolongs the Antioxidant Effect to Beyond That of Each Component Alone in Vivo |
Jeon, Hee-Young
(Food Research Institute, Amorepacific Corporation R&D Center)
Kim, Jeong-Kee (Food Research Institute, Amorepacific Corporation R&D Center) Lee, Ji-Eun (Food Research Institute, Amorepacific Corporation R&D Center) Shin, Hyun-Jung (Food Research Institute, Amorepacific Corporation R&D Center) Lee, Sang-Jun (Food Research Institute, Amorepacific Corporation R&D Center) |
1 | MacMahon MT, Neale G. The absorption of alpha-tocopherol in control subjects and in patients with intestinal malabsorption. Clin. Sci. 38: 197-210 (1970) DOI |
2 | Bray TM. Dietary antioxidants and assessment of oxidative stress. Nutrition 16: 578-581 (2000) DOI ScienceOn |
3 | Sharma RA, Gescher AJ, Steward WP. Curcumin: The story so far. Eur. J. Cancer. 41: 1955-1968 (2005) DOI ScienceOn |
4 | Tayyem RF, Heath DD, Al-Delaimy WK, Rock CL. Curcumin content of turmeric and curry powders. Nutr. Cancer. 55: 126-131 (2006) DOI ScienceOn |
5 | Miller NJ, Johnston JD, Collis CS, Rice-Evans C. Serum total antioxidant activity after myocardial infarction. Ann. Clin. Biochem. 34: 85-90 (1997) DOI |
6 | Blanchard J, Conrad KA, Mead RA, Garry PJ. Vitamin C disposition in young and elderly men. Am. J. Clin. Nutr. 51: 837-845 (1990) DOI |
7 | Somparn P, Phisalaphong C, Nakornchai S, Unchern S, Morales NP. Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives. Biol. Pharm. Bull. 30: 74-78 (2007) DOI ScienceOn |
8 | Kadoma Y, Ishihara M, Okada N, Fujisawa S. Free radical interaction between vitamin E (alpha-, beta-, gamma-, and delta-tocopherol) ascorbate and flavonoids. In Vivo 20: 823-827 (2006) |
9 | Ratnam DV, Ankola DD, Bhardwaj V, Sahana DK, Kumar MN. Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective. J. Control Release 113: 189-207 (2006) DOI ScienceOn |
10 | McArdle F, Rhodes LE, Parslew RAG, Close GL, Jack CIA, Friedmann PS, Jackson MJ. Effects of oral vitamin E and supplementation on ultraviolet radiation-induced oxidative stress in human skin. Am. J. Clin. Nutr. 80: 1270-1275 (2004) DOI |
11 | Breslin DS, Jiao K, Habib AS, Schultz J, Gan TJ. Pharmaco-dynamic interactions between cisatracurium and rocuronium. Anesth. Analg. 98: 107-110 (2004) |
12 | Eybl V, Kotyzova D Leseticky L, Bludovska M, Koutensky J. The influence of curcumin and manganese complex of curcumin on cadmium-induced oxidative damage and trace elements status in tissues of mice. J. Appl. Toxicol. 26: 207-212 (2005) DOI ScienceOn |
13 | Cohn W. Bioavailability of vitamin E. Eur. J. Clin. Nutr. 51: S80-S85 (1997) |
14 | Yogeeta SK, Gnanapragasam A, Kumar SS, Subhashini R, Sathivel A, Devaki T. Synergistic interactions of ferulic acid with ascorbic acid: Its cardioprotective role during isoproterenol induced myocardial infarction in rats. Mol. Cell. Biochem. 283: 139-146 (2006) DOI |
15 | Sies H. Strategies of antioxidant defense. Eur. J. Biochem. 215: 213-219 (1993) DOI ScienceOn |
16 | Ferslew KE, Acuff RV, Daigneault EA. Pharmacokinetics and bioavailability of the RRR and all racemic stereoisomers of alpha-tocopherol in humans after single oral administration. J. Clin. Pharmacol. 33: 84-88 (1993) DOI |
17 | Cheng AL, Hsu CH, Lin JK. Phase I clinical trial of curcumin a chemopreventive agent in patients with high-risk or pre-malignant lesions. Anticancer Res. 21: 2895-2900 (2001) |
18 | Julianto T, Yuen KH, Noor AM. Improved bioavailability of vitamin E with self emulsifying formulation. Int. J. Pharm. 200: 53-57 (2000) DOI ScienceOn |
19 | Levine M, Conry-Cantilena C, Wang Y. Vitamin C pharmacokinetics in healthy volunteers: Evidence for a recommended dietary allowance. P. Natl. Acad. Sci. USA 93: 3704-3709 (1996) |
20 | Calabrese V, Butterfield DA, Stella AM. Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: Novel targets for neuroprotection in Alzheimer's disease. Ital. J. Biochem. 52: 177-181 (2003) |
21 | Manea C, Souquet JM, Ollea D, Verrieas C, Vearan F, Mazerolles G, Cheynier V, Fulcrand H. Optimization of simultaneous flavanol phenolic acid and anthocyanin extraction from grapes using an experimental design: Application to the characterization of champagne grape varieties. J. Agr. Food Chem. 55: 7224-7233 (2007) DOI ScienceOn |
22 | Ermer JC, Shojaei A, Pennick M, Anderson CS, Silverberg A, Youcha SH. Bioavailability of triple-bead mixed amphetamine salts compared with a dose-augmentation strategy of mixed amphetamine salts extended release plus mixed amphetamine salts immediate release. Curr. Med. Res. Opin. 23: 1067-1075 (2007) DOI ScienceOn |
23 | Leichtnam ML, Rolland H, Wüthrich P, Guy RH. Formulation and evaluation of a testosterone transdermal spray. J. Pharm. Sci. 95: 1693-1702 (2006) DOI ScienceOn |
24 | Cheeseman KH, Holley AE, Kelly FJ. Biokinetics in humans of RRR-alpha-tocopherol: The free phenol acetate ester and succinate ester forms of vitamin E. Free Radical Bio. Med. 19: 591-598 (1995) DOI ScienceOn |
25 | Reboul E, Thap S, Tourniaire F, André M, Juhel C, Morange S, Amiot MJ, Lairon D, Borel P. Differential effect of dietary antioxidant classes (carotenoids, polyphenols, vitamins C and E) on lutein absorption. Brit. J. Nutr. 97: 440-446 (2007) DOI ScienceOn |
26 | Chen CY, Milbury PE, Lapsley K, Blumberg JB. Flavonoids from almond skins are bioavailable and act synergistically with vitamins C and E to enhance hamster and human LDL resistance to oxidation. J. Nutr. 135: 1366-1373 (2005) DOI |
27 | Richelle M, Sabatier M, Steiling H, Williamson G. Skin bioavailability of dietary vitamin E, carotenoids, polyphenols, vitamin C, zinc, and selenium. Brit. J. Nutr. 96: 227-238 (2006) DOI ScienceOn |
28 | Serafini M, Ghiselli A, Ferro-Luzzi A. In vivo antioxidant effect of green and black tea in man. Eur. J. Clin. Nutr. 50: 28-32 (1996) |
29 | Flood P. The importance of myorelaxants in anesthesia. Curr. Opin. Pharmacol. 5: 322-327 (2005) DOI ScienceOn |
30 | Tyssandier V, Cardinault N, Caris-Veyrat C, Amiot MJ, Grolier P, Bouteloup C, Azais-Braesco V, Borel P. Vegetable-borne lutein lycopene and compete for incorporation into chylomicrons with no adverse effect on the medium-term (3-wk) plasma status of carotenoids in humans. Am. J. Clin. Nutr. 75: 526-534 (2002) DOI |
31 | Choi JM, Han J, Yoon BS, Chung JH, Shin DB, Lee SK, Hwang JK, Ryang R. Antioxidant properties of tannic acid and its inhibitory effects on paraquat-induced oxidative stress in mice. Food Sci. Biotechnol. 15: 728-734 (2006) 과학기술학회마을 |
32 | Lin JH. Pharmacokinetic and pharmacodynamic variability: A daunting challenge in drug therapy. Curr. Drug Metab. 8: 109-136 (2007) DOI ScienceOn |
33 | El-Malah Y, Nazzal S, Khanfar NM. D-Optimal mixture design: Optimization of ternary matrix blends for controlled zero-order drug release from oral dosage forms. Drug Dev. Ind. Pharm. 32: 1207-1218 (2006) DOI ScienceOn |
34 | van den Berg H. Carotenoid interactions. Nutr. Rev. 57: 1-10 (1999) |
35 | Yang KY, Lin LC, Tseng TY, Wang SC, Tsai TH. Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS. J. Chromatogr. B 853: 183-189 (2007) DOI ScienceOn |
36 | Murugan P, Pari L. Effect of tetrahydrocurcumin on plasma antioxidants in streptozotocin-nicotinamide experimental diabetes. J. Basic Clin. Physiol. Pharmacol. 17: 231-244 (2006) |
37 | Niki E. Interaction of ascorbate and alpha-tocopherol. Ann. NY Acad. Sci. 498: 186-199 (1987) DOI ScienceOn |
38 | Hornig D. Metabolism and requirements of ascorbic acid in man. S. Afr. Med. J. 60: 818-823 (1981) |
39 | Schwedhelm E, Maas R, Troost R, Boger RH. Clinical pharmacokinetics of antioxidants and their impact on systemic oxidative stress. Clin. Pharmacokinet. 42: 437-459 (2003) DOI ScienceOn |
40 | Miller NJ, Rice-Evans C, Davies MJ, Gopinathan V, Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin. Sci. 84: 407-412 (1993) DOI |
41 | Banfi G, Malavazos A, Iorio E, Dolci A, Doneda L, Verna R, Corsi MM. Plasma oxidative stress biomarkers nitric oxide and heat shock protein 70 in trained elite soccer. Eur. J. Appl. Physiol. 96: 483-486 (2006) DOI ScienceOn |
42 | Blanchard J. Depletion and repletion kinetics of vitamin C in humans. J. Nutr. 121: 170-176 (1991) DOI |
43 | Ko SH, Choi SW, Ye SK, Cho BL, Kim HS. Comparison of the antioxidant activities of nine different fruits in human plasma. J. Med. Food. 8: 41-46 (2005) DOI ScienceOn |
44 | Ma Z, Shayeganpour A, Brocks DR, Lavasanifar A, Samuel J. High performance liquid chromatography analysis of curcumin in rat plasma: Application to pharmacokinetics of polymeric micellar formulation of curcumin. Biomed. Chromatogr. 21: 546-552 (2007) DOI ScienceOn |