• Title/Summary/Keyword: Optimal alternative

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Financial Feasibility Analysis for the Development of Urban Telecommunication Facility Purpose Site (도심 통신기반시설용지의 개발을 위한 재무타당성 분석에 관한 연구)

  • Park, Kyungyong;Jeong, Moonoh;Lee, Sangyoub
    • Korean Journal of Construction Engineering and Management
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    • v.16 no.5
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    • pp.31-41
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    • 2015
  • The telecommunication industry has been considered as a national fundamental infrastructure. However, due to the rapid evolution of technology and the change of industry market conditions, the telecommunication infrastructure needs no more huge space for facility and it leads its use to the mixed-use development based on private investment. This study intends to examine the financial feasibility of the development project for the optimal alternative use of telecommunication facility purpose site as a case study based on two types: contributed acceptance and multi-level designation. The NPA and IRR has been analyzed by the simulation of stochastic variables including rent price and its variation rate, vacancy rate, construction cost, capitalization rate and discount rate. The research finding indicates that the two types of development are satisfied with the financial feasibility and it is noteworthy that the rent price turns out to be the most critical factor for the project. Accordingly, it is expected that these research finding can be applied for providing the solid cases of financial feasibility analysis for the development project in limited use of telecommunication facility purpose site.

Establishment of Quality Control System for Angiographic Unit (IVR장치의 성능 평가 기준 개발)

  • Kang, Byung-Sam;Son, Jin-Hyun;Kim, Seung-Chul
    • The Journal of the Korea Contents Association
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    • v.11 no.1
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    • pp.236-244
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    • 2011
  • Recently, the number of interventional procedures has increased dramatically as an alternative of invasive surgical procedure. The need for the quality control program of the angiographic units has also increased, because of concerns about the increased patient dose and the importance of image quality of angiographic units for the successful procedures. The purpose of this study was to propose an optimal guideline for the quality control program of the angiographic units. We reviewed domestic and international standards about medical imaging system and we evaluated the quality of 61 angiographic units in Korea with the use of NEMA 21 phantom. According to the results of our study, we propose a guideline for the quality control program of the angiographic units. Quality control program includes tube voltage test, tube current test, HVL test, image-field geometry test, spatial resolution test, low-contrast iodine detectability test, wire resolution test, phantom entrance dose test. Proposed reference levels are as follows: PAE < $\pm$ 10% in tube voltage test, PAE < $\pm$ 15% in tube current test, minimum 2.3 mmAl at 80 kVp in HVL test, minimum 'acceptable' level at image-field geometry test, 0.8 lp/mm for detector size of 34-40cm, 1.0 lp/mm for detector size of 28-33cm, 1.2 lp/mm for detector size of 22-27cm in spatial resolution test, minimum 200mg/cc in low contrast iodine detectability test, phantom entrance dose should be under 10R/min, 0.012 inch wire should be seen at static wire resolution test, and 0.022 inch wire should be seen at moving wire resolution test.

Enhanced Production of Astaxanthin in Paracoccus haeundaensis Strain by Physical and Chemical Mutagenesis (물리·화학적 돌연변이 유도를 통한 Paracoccus haeundaensis의 astaxanthin 생산량 증대)

  • Seo, Yong Bae;Jeong, Tae Hyug;Choi, Seong Seok;Lim, Han Kyu;Kim, Gun-Do
    • Journal of Life Science
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    • v.27 no.3
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    • pp.339-345
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    • 2017
  • Carotenoids are natural lipid-soluble pigments, which are produced primarily by bacteria, algae, and plants. Many studies have focused on the identification, production, and utilization of natural sources of astaxanthin from algae, yeast, and crustacean byproducts as an alternative to the synthetic pigment, which is mostly used today. The aim of the present study was to identify a mutant of Paracoccus haeundaensis by exposure to UV and ethyl methanesulfonate (EMS). The mutant was then exposed to nutrient stress conditions to isolate an astaxanthin-hyperproducing strain, followed by characterization of the mutant. The survival rate decreased in accordance with an increase in the UV exposure time and an increase in the EMS concentration. A mutant of the original P. haeundaensis strain was identified that showed hyperproduction of astaxanthin following exposure to UV irradiation (20 min) and EMS treatment (0.4 M concentration). The optimal culture conditions for the PUE mutant were $25^{\circ}C$, pH 7-8, and 3% NaCl. The effects of various carbon and nitrogen sources on the growth and astaxanthin production of PUE were examined. The addition of 1% raffinose and 3% potassium nitrate influenced cell growth and astaxanthin production. The selected mutant exhibited an increase of 1.58 folds in astaxanthin content compared to initial wild type strain. A genetically stable mutant strain obtained using mutagen (UV irradiation and EMS treatment) may be a suitable candidate for further industrial scale production of astaxanthin.

AUTOTRANSPLANTATION OF IMPACTED MAXILLARY CANINES (매복된 상악 견치의 자가치아이식을 통한 치험례)

  • Kim, Tae-Wan;Kim, Hyun-Jung;Kim, Young-Jin;Nam, Soon-Hyeun
    • Journal of the korean academy of Pediatric Dentistry
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    • v.30 no.2
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    • pp.326-333
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    • 2003
  • The appropriate treatment for eruption guide of impacted teeth necessitates the formulation of a comprehensive treatment plan, which is dependent upon a number of factors such as the condition of the deciduous teeth, dental and skeletal relationship, dental age of the patient, willingness of the patient to undergo extensive dental treatment and financial considerations. If the etiology of the eruption disturbance has been identified, the elimination of the causes and various procedures can be used for eruption guide. Particularly the transplantation is a valuable alternative to extraction of impacted teeth, where surgical exposure and subsequent orthodontic realignment are difficult or impossible. This report present three cases of autotransplantation of impacted maxillary canine. As the result in these cases, atraumatic removal of donor tooth during operation is prerequisite to an optimal clinical result. Due to a high possibility of pulp necrosis, endodontic treatment of fully developed transplanted teeth should be undertaken. In complex case, autotransplantation can save time and less expensive than orthodontic forced eruption. Recipient socket should be prepared to a size that is slightly larger than the root of the donor tooth, and can be prepared with open or close procedure depends on root size of donor tooth and buccolingual width at transplantion site.

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Long-term clinical outcome of acute myocardial infarction according to the early revascularization method: a comparison of primary percutaneous coronary interventions and fibrinolysis followed by routine invasive treatment

  • Min, Hyang Ki;Park, Ji Young;Choi, Jae Woong;Ryu, Sung Kee;Kim, Seunghwan;Song, Chang Sup;Kim, Dong Shin;Song, Chi Woo;Kim, Se Jong;Kim, Young Bin
    • Journal of Yeungnam Medical Science
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    • v.34 no.2
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    • pp.191-199
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    • 2017
  • Background: This study was conducted to provide a comparison between the clinical outcomes of primary percutaneous coronary intervention (PCI) and that of fibrinolysis followed by routine invasive treatment in ST elevation myocardial infarction (STEMI). Methods: A total of 184 consecutive STEMI patients who underwent primary PCI or fibrinolysis followed by a routine invasive therapy were enrolled from 2004 to 2011, and their major adverse cardiovascular events (MACEs) were compared. Results: Among the 184 patients, 146 patients received primary PCI and 38 patients received fibrinolysis. The baseline clinical characteristics were similar between both groups, except for triglyceride level ($68.1{\pm}66.62$ vs. $141.6{\pm}154.3mg/dL$, p=0.007) and high density lipoprotein level ($44.6{\pm}10.3$ vs. $39.5{\pm}8.1mg/dL$, p=0.005). The initial creatine kinase-MB level was higher in the primary PCI group ($71.5{\pm}114.2$ vs. $35.9{\pm}59.9ng/mL$, p=0.010). The proportion of pre-thrombolysis in MI 0 to 2 flow lesions (92.9% vs. 73.0%, p<0.001) was higher and glycoprotein IIb/IIIa inhibitors were administered more frequently in the primary PCI group. There was no difference in the 12-month clinical outcomes, including all-cause mortality (9.9% vs. 8.8%, p=0.896), cardiac death (7.8% vs. 5.9%, p=0.845), non-fatal MI (1.4% vs. 2.9%, p=0.539), target lesion revascularization (5.7% vs. 2.9%, p=0.517), and stroke (0% vs. 0%). The MACEs free survival rate was similar for both groups (odds ratio, 0.792; 95% confidence interval, 0.317-1.980; p=0.618). The clinical outcome of thrombolysis was not inferior, even when compared with primary PCI performed within 90 minutes. Conclusion: Early fibrinolysis with optimal antiplatelet and antithrombotic therapy followed by appropriate invasive procedure would be a comparable alternative to treatment of MI, especially in cases of shorter-symptom-to-door time.

Hierarchical Internet Application Traffic Classification using a Multi-class SVM (다중 클래스 SVM을 이용한 계층적 인터넷 애플리케이션 트래픽의 분류)

  • Yu, Jae-Hak;Lee, Han-Sung;Im, Young-Hee;Kim, Myung-Sup;Park, Dai-Hee
    • Journal of the Korean Institute of Intelligent Systems
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    • v.20 no.1
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    • pp.7-14
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    • 2010
  • In this paper, we introduce a hierarchical internet application traffic classification system based on SVM as an alternative overcoming the uppermost limit of the conventional methodology which is using the port number or payload information. After selecting an optimal attribute subset of the bidirectional traffic flow data collected from the campus, the proposed system classifies the internet application traffic hierarchically. The system is composed of three layers: the first layer quickly determines P2P traffic and non-P2P traffic using a SVM, the second layer classifies P2P traffics into file-sharing, messenger, and TV, based on three SVDDs. The third layer makes specific classification of the entire 16 application traffics. By classifying the internet application traffic finely or coarsely, the proposed system can guarantee an efficient system resource management, a stable network environment, a seamless bandwidth, and an appropriate QoS. Also, even a new application traffic is added, it is possible to have a system incremental updating and scalability by training only a new SVDD without retraining the whole system. We validate the performance of our approach with computer experiments.

A Classified Space VQ Design for Text-Independent Speaker Recognition (문맥 독립 화자인식을 위한 공간 분할 벡터 양자기 설계)

  • Lim, Dong-Chul;Lee, Hanig-Sei
    • The KIPS Transactions:PartB
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    • v.10B no.6
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    • pp.673-680
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    • 2003
  • In this paper, we study the enhancement of VQ (Vector Quantization) design for text independent speaker recognition. In a concrete way, we present a non-iterative method which makes a vector quantization codebook and this method performs non-iterative learning so that the computational complexity is epochally reduced The proposed Classified Space VQ (CSVQ) design method for text Independent speaker recognition is generalized from Semi-noniterative VQ design method for text dependent speaker recognition. CSVQ contrasts with the existing desiEn method which uses the iterative learninE algorithm for every traininE speaker. The characteristics of a CSVQ design is as follows. First, the proposed method performs the non-iterative learning by using a Classified Space Codebook. Second, a quantization region of each speaker is equivalent for the quantization region of a Classified Space Codebook. And the quantization point of each speaker is the optimal point for the statistical distribution of each speaker in a quantization region of a Classified Space Codebook. Third, Classified Space Codebook (CSC) is constructed through Sample Vector Formation Method (CSVQ1, 2) and Hyper-Lattice Formation Method (CSVQ 3). In the numerical experiment, we use the 12th met-cepstrum feature vectors of 10 speakers and compare it with the existing method, changing the codebook size from 16 to 128 for each Classified Space Codebook. The recognition rate of the proposed method is 100% for CSVQ1, 2. It is equal to the recognition rate of the existing method. Therefore the proposed CSVQ design method is, reducing computational complexity and maintaining the recognition rate, new alternative proposal and CSVQ with CSC can be applied to a general purpose recognition.

An Analysis of Stress Transfer Behaviors within the Necrotic Cancellous Bone following Surgical Procedures or the Management of the Osteonecrosis of the Femoral Head (대퇴골두 무혈성 괴사증의 수술적 기법 적용 후 괴사 망상골 내에서의 응력 변화 해석)

  • Kim, J.S.;Lee, S.J.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.11
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    • pp.245-248
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    • 1997
  • Operative interventions for the management of osteonecrosis of the femoral head (ONFH) include core drilling, with or without vascularized fibular bone grafting. Nevertheless, their clinical results have not been consistently satisfactory. Recently, a new surgical procedure that incorporates cementation with polymethylmethacrylate (PMMA) after core drilling has been tried clinically. In this study, a biomechanical analysis using a finite element method(FEM) was undertaken to evaluate surgical methods and their underlying surgical parameter. Our finite element models included five types. They were (1) normal model (Type I), (2) necrotic model (Type II), (3) core decompressed model (Type III). (4) fibular bone grafted model (Type IV), and (5) cemented with PMMA model (Type V). The geometric dimensions of the femur were based on digitized CT-scan data of a normal person. Various physiological loading conditions and surgical penetration depths by the core were used as mechanical variables to study their biomechanical contributions in stress transfer within the femoral head region. In addition. the peak von Mises stress(PVMS) within the necrotic cancellous bone of the femoral head was obtained. The fibular bone grafted method and cementation method provided optimal stress transfer behaviors. Here. substantial increase in the low stress level was observed when the penetration depth was extended to 0mm and 5mm from the subchondral region. Moreover, significant decrease in PVMS due to surgery was observed in the fibular bone grafted method and the cementation method when the penetration depths were extended up to 0 and 5mm from the subchondral region. The drop in PVMS was greater during toe-off than during heel-strike (57% vs. 28% in Type IV and 49% vs. 22% in Type V). Both the vascularized fibular bone grafting method (Type IV) and the new PMMA technique (Type V) appear to be very effective in providing good stress transfer and reducing the peak Von-Mises stress within the necrotic region. Overall results show that fibular bone grafting and cementation methods are quite similar. In light of above results, the new cementation method appears to be a promising surgical alternative or the treatment of ONFH. The use of PMMA for the core can be less prone to surgical complication as opposed to preparation of fibular bone graft and can achieve more immediate fixation between the core and the surrounding region.

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Reverse Transcription Loop-Mediated Isothermal Amplification Assay for Rapid Detection of Soybean yellow mottle mosaic virus (콩황화모틀모자이크바이러스의 신속검출을 위한 역전사 등온증폭법)

  • Bae, Dae Hyeon;Park, Chung Youl;Kim, Bong-Sub;Lee, Yeong-Hoon;Yoon, Young-Nam;Kang, Hang Won;Oh, Jonghee;Lee, Su-Heon
    • Research in Plant Disease
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    • v.22 no.3
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    • pp.178-183
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    • 2016
  • Soybean yellow mottle mosaic virus (SYMMV) is a new emerging plant virus detected in soybean (Glycine max) in Korea. Reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for rapid detection of SYMMV has been developed. In this study, we have designed primers (SYMM-F3/B3/FIP/BIP) specific to sequences from the coat protein gene of SYMMV genome. Sensitivity analysis showed that RT-LAMP was 10 to 100 times more sensitive than reverse transcription polymerase chain reaction (RT-PCR). The optimal reaction condition of RT-LAMP was determined at $65^{\circ}C$ for 50 minutes. The result indicates that RT-LAMP assay does not require special equipment and long time for SYMMV detection. Therefore, it can be an alternative detection method of RT-PCR in laboratory.

Dynamic traffic assignment based on arrival time-based OD flows (도착시간 기준 기종점표를 이용한 동적통행배정)

  • Kim, Hyeon-Myeong
    • Journal of Korean Society of Transportation
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    • v.27 no.1
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    • pp.143-155
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    • 2009
  • A dynamic traffic assignment (DTA) has recently been implemented in many practical projects. The core of dynamic model is the inclusion of time scale. If excluding the time dimension from a DTA model, the framework of a DTA model is similar to that of static model. Similar to static model, with given exogenous travel demand, a DTA model loads vehicles on the network and finds an optimal solution satisfying a pre-defined route choice rule. In most DTA models, the departure pattern of given travel demand is predefined and assumed as a fixed pattern, although the departure pattern of driver is changeable depending on a network traffic condition. Especially, for morning peak commute where most drivers have their preferred arrival time, the departure time, therefore, should be modeled as an endogenous variable. In this paper, the authors point out some shortcomings of current DTA model and propose an alternative approach which could overcome the shortcomings of current DTA model. The authors substitute a traditional definition for time-dependent OD table by a new definition in which the time-dependent OD table is defined as arrival time-based one. In addition, the authors develop a new DTA model which is capable of finding an equilibrium departure pattern without the use of schedule delay functions. Three types of objective function for a new DTA framework are proposed, and the solution algorithms for the three objective functions are also explained.