• Title/Summary/Keyword: Optimal Margin

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Adjustable Ghajar Guide Technique for Accurate Placement of Ventricular Catheters : A Pilot Study

  • Yoon, Sang-Youl;Kwak, Youngseok;Park, Jaechan
    • Journal of Korean Neurosurgical Society
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    • v.60 no.5
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    • pp.604-609
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    • 2017
  • Objective : An adjustable Ghajar guide is presented to improve the accuracy of the original Ghajar guide technique. The accuracy of the adjustable Ghajar guide technique is also investigated. Methods : The coronal adjustment angle from the orthogonal catheter trajectory at Kocher's point is determined based on coronal head images using an electronic picture archiving and communication system. For the adjustable Ghajar guide, a protractor is mounted on a C-shaped basal plate that is placed in contact with the margin of a burrhole, keeping the central $0^{\circ}$ line of the protractor orthogonal to the calvarial surface. A catheter guide, which is moved along the protractor and fixed at the pre-determined adjustment angle, is then used to guide the ventricular catheter into the frontal horn adjacent to the foramen of Monro. The adjustable Ghajar guide technique was applied to 20 patients, while a freehand technique based on the surface anatomy of the head was applied to another 47 patients. The accuracy of the ventricular catheter placement was then evaluated using postoperative computed tomography scans. Results : For the adjustable Ghajar guide technique (AGT) patients, the bicaudate index ranged from 0.23 to 0.33 ($mean{\pm}standard$ deviation [SD] : $0.27{\pm}0.03$) and the adjustment angle ranged from $0^{\circ}$ to $10^{\circ}$ ($mean{\pm}SD:5.2^{\circ}{\pm}3.2^{\circ}$). All the AGT patients experienced successful cerebrospinal fluid diversion with only one pass of the catheter. Optimal placement of the ventricular catheter in the ipsilateral frontal horn approximating the foramen of Monro (grade 1) was achieved in 19 patients (95.0%), while a suboptimal trajectory into a lateral corner of the frontal horn passing along a lateral wall of the frontal horn (grade 3) occurred in 1 patient (5.0%). Thus, the AGT patients experienced a significantly higher incidence of optimal catheter placement than the freehand catheterized patients (95.0% vs. 68.3%, p=0.024). Moreover, none of the AGT patients experienced any tract hemorrhages along the catheter or procedure-related complications. Conclusion : The proposed adjustable Ghajar guide technique, using angular adjustment in the coronal plane from the orthogonal trajectory at Kocher's point, facilitates accurate freehand placement of a ventricular catheter for hydrocephalic patients.

Application of the ExacTrac System in Respiratory Gated Radiotherapy for Lung Cancer Patients (폐암 환자의 호흡연동방사선치료를 위한 ExacTrac 시스템 적용)

  • Ko, Seung Young;Lee, Jung Il
    • Journal of the Korean Society of Radiology
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    • v.13 no.3
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    • pp.325-332
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    • 2019
  • This study analyzed the movement of tumors using 4DCT. Appropriate uniform IM were identified using TC, II and CI depending on ITV margins. DVH and NTCP were also compared in each case. Dose analysis on tumors with uniform IM showed that the optimal treatment plan for satisfying all TC, CI, II was evaluated as 2 mm in phase 20 and 3 mm in 40%. That was compared to the dose from the normal tissues of $PTV_{20}$, $PTV_{40}$. In the 20% radiation field, V5, V10, and V20 for the lungs increased 1.49, 1.26, and 0.65%, while 40% increased by 1.9, 2.41 and 1.23%. NTCP had a dose increase of 0.57 to 0.029% from 20% and 40%. There was a dose increase in the spinal cord and heart at uniform IM, but there was no significant difference. These data suggest that the ITV setting of 20%, phase for Respiratory Gated Radiotherapy using Novalis ExacTrac system can be applied with a uniform IM 2 mm and 40% with 3 mm for optimal treatment plan.

Treatment Outcome of Thymic Epithelial Tumor: Prognostic Factors and Optimal Postoperative Radiation Therapy (흉선상피종의 치료 성적: 예후 인자 및 방사선치료 방법에 대한 연구)

  • Oh Dong Ryul;Ahn Yong Chan;Kim Kwan Min;Kim Jhingook;Shim Young Mog;Han Jung Ho
    • Radiation Oncology Journal
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    • v.23 no.2
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    • pp.85-91
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    • 2005
  • Purpose : This study was conducted to analyze treatment outcome and prognostic significance of World Health Organization (WHO)-defined thymic epithelial tumor (TET) subtype and to assess optimal radiation target volume in patients receiving surgery and adjuvant radiation therapy with TET. Materials and Methods: The record of 160 patients with TET, who received surgical resection at the Samsung medical Center, from December 1994 to June 2004, were reviewed. 99 patients were treated with postoperative radiation therapy (PORT). PORT was recommended when patients had more than one findings among suspicious Incomplete resection or positive resection margin or Wasaoka stage $II\~IV$ or WHO type $B2\~C$. PORT peformed to primary tumor bed only with a mean dose of 54 Gy. The prognostic factor and pattern of failure were analyzed retrospectively. Results : The overall survival rate at 5 years was $87.3\%$. Age (more than 60 years $77.8\%$, less than 60 years $91.1\%$; p=0.03), Wasaoka stage (I $92.2\%$, II $95.4\%$, III $82.1\%$, IV $57.5\%$; p=0.001), WHO tumor type (A-Bl $96.0\%$, B2-C $82.3\%$; p=0.001), Extent of resection (R0 resection $92.3\%$, R1 or 2 resection $72.6\%$, p=0.001) were the prognostic factors according to univariate analysis. But WHO tumor type was the only significant prognostic factor according to multivariate analysis. Recurrence was observed in 5 patients of 71 Masoka stage I-III patients who received grossly complete tumor removal (R0, R1 resection) and PORT to primary tumor bed. Mediastinal recurrence was observed In only one patients. There were no recurrence within irradiation field. Conclusion : WHO tumor type was the important prognostic factor to predict survival of patients with TET. This study suggest that PORT to only primary tumor bed was optimal. To avoid pleura- or pericardium-based recurrence, further study of effective chemotherapy should be investigated.

Subbrow Approach as a Minimally Invasive Reduction Technique in the Management of Frontal Sinus Fractures

  • Lee, Yewon;Choi, Hyun Gon;Shin, Dong Hyeok;Uhm, Ki Il;Kim, Soon Heum;Kim, Cheol Keun;Jo, Dong In
    • Archives of Plastic Surgery
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    • v.41 no.6
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    • pp.679-685
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    • 2014
  • Background Frontal sinus fractures, particularly anterior sinus fractures, are relatively common facial fractures. Many agree on the general principles of frontal fracture management; however, the optimal methods of reduction are still controversial. In this article, we suggest a simple reduction method using a subbrow incision as a treatment for isolated anterior sinus fractures. Methods Between March 2011 and March 2014, 13 patients with isolated frontal sinus fractures were treated by open reduction and internal fixation through a subbrow incision. The subbrow incision line was designed to be precisely at the lower margin of the brow in order to obtain an inconspicuous scar. A periosteal incision was made at 3 mm above the superior orbital rim. The fracture site of the frontal bone was reduced, and bone fixation was performed using an absorbable plate and screws. Results Contour deformities were completely restored in all patients, and all patients were satisfied with the results. Scars were barely visible in the long-term follow-up. No complications related to the procedure, such as infection, uncontrolled sinus bleeding, hematoma, paresthesia, mucocele, or posterior wall and brain injury were observed. Conclusions The subbrow approach allowed for an accurate reduction and internal fixation of the fractures in the anterior table of the frontal sinus by providing a direct visualization of the fracture. Considering the surgical success of the reduction and the rigid fixation, patient satisfaction, and aesthetic problems, this transcutaneous approach through a subbrow incision is concluded to be superior to the other reduction techniques used in the case of an anterior table frontal sinus fracture.

A Study on the development of a decision model on free flow and congested traffic conditions to determine the optimal ventilation capacity in highway tunnels (고속도로 터널의 적정 환기용량 계획을 위한 원활 및 지체조건 판별모델 개발에 대한 연구)

  • Kim, Hyo-Gyu;Yoo, Ji-Oh;Lee, Chang-Woo
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.14 no.4
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    • pp.375-395
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    • 2012
  • According to the local highway tunnel ventilation guideline, ventilation capacity calculation should be performed at the speed ranging from 10 km/h to 80 km/h. This is so reasonable method considering uncongested and congested traffic conditions in urban tunnels. But recently due to low traffic volume and very low congestion frequency in rural highway tunnels, it seems to be an inadequate way to apply the guideline. Therefore the calculation should be performed separately for the free flow and congested traffic cases classified by the appropriate decision model. This paper aims at determining unnecessary running speed range for reasonable tunnel ventilation design, considering free flow and congested traffic conditions. Firstly, traffic volumes in highway tunnels were collected and if any, the causes of congestion were investigated. And with concept of 'margin speed'($u-u_m$), the decision model on traffic congestion was developed. Applicability of the decision model was also analyzed with case study. According to the results, when design speed is 100 km/h, with V/C less than 0.1, then the range of unnecessary speed in tunnel ventilation design is less than 40 km/h; for $V/C{\leqq}0.35$, $V/C{\leqq}0.6$ and $V/C{\leqq}0.75$, the unnecessary speed ranges are found to be ${\leqq}30$, ${\leqq}20$ and ${\leqq}10km/h$, respectively.

Recycling of end-of-life LiNixCoyMnzO2 batteries for rare metals recovery

  • Sattar, Rabia;Ilyas, Sadia;Kousar, Sidra;Khalid, Amaila;Sajid, Munazzah;Bukhari, Sania Iqbal
    • Environmental Engineering Research
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    • v.25 no.1
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    • pp.88-95
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    • 2020
  • An investigation of rare metals recovery from LiNixCoyMnzO2 cathode material of the end-of-life lithium-ion batteries is presented. To determine the influence of reductant on the leach process, the cathode material (containing Li 7.6%, Co 20.4%, Mn 19.4%, and Ni 19.3%) was leached in H2SO4 solutions either with or without H2O2. The optimal process parameters with respect to acid concentration, addition dosage of H2O2, temperature, and the leaching time were found to be 2.0 M H2SO4, 4 vol.% H2O2, 70℃, and 150 min, respectively. The yield of metal values in the leach liquor was > 99%. The leach liquor was subsequently treated by precipitation techniques to recover nickel as Ni(C4H7N2O2)2 and lithium as Li2CO3 with stoichiometric ratios of 2:1 and 1.2:1 of dimethylglyoxime:Ni and Na2CO3:Li, respectively. Cobalt was recovered by solvent extraction following a 3-stage process using Na-Cyanex 272 at pHeq ~5.0 with an organic-to-aqueous phase ratio (O/A) of 2/3. The loaded organic phase was stripped with 2.0 M H2SO4 at an O/A ratio of 8/1 to yield a solution of 114 g/L CoSO4; finally recovered CoSO4.xH2O by crystallization. The process economics were analyzed and found to be viable with a margin of $476 per ton of the cathode material.

Study on Variable Systems for Compressor and Turbine and its Control Scheme (압축기 정익, 터빈 노즐 가변 메카니즘 및 제어기법 연구)

  • Kim, Sangjo;Kim, Donghyun;Bae, Kyoungwook;Kim, Dae-il;Son, Changmin;Kim, Kuisoon;Lee, Daewoo;Go, Jeungsang;Choi, Dong-Whan;Kim, Myungho;Min, Seongki
    • Journal of the Korean Society of Propulsion Engineers
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    • v.19 no.5
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    • pp.1-14
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    • 2015
  • In case of a gas turbine engine for supersonic operation, the engine have a wide range of operating inlet mass flow rate and required high performance such as thrust and fuel consumption. Therefore, variable system and its optimal control logic are essentially needed. In this work, a method for performance prediction of a gas turbine engine with variable system compressor and its control scheme were developed. Conceptual design of compact acuation system for the operation of the variable system was also conducted. The performance of a low-bypass ratio mixed flow turbofan engine was analyzed, and it was observed that the surge margin of the engine is improved at off-design condition by applying the control scheme.

Design of Digital PLL with Asymmetry Compensator in High Speed DVD Systems (고속 DVD 시스템에서 비대칭 신호 보정기와 결합한 Digital PLL 설계)

  • 김판수;고석준;최형진;이정현
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.26 no.12A
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    • pp.2000-2011
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    • 2001
  • In this Paper, we convert conventional low speed(1x, 6x) DVD systems designed by analog PLL(Phase Locked Loop) into digital PLL to operate at high speed systems flexibly, and present optimal DPLL model in high speed(20x) DVD systems. Especially, we focused on the design of DPLL that can overcome channel effects such as bulk delay, sampling clock frequency offset and asymmetry phenomenon in high speed DVD systems. First, the modified Early-Late timing error detector as digital timing recovery scheme is proposed. And the four-sampled compensation algorithm using zero crossing point as asymmetry compensator is designed to achieve high speed operation and strong reliability. We show that the proposed timing recovery algorithm provides enhanced performances in jitter valiance and SNR margin by 4 times and 3dB respectively. Also, the new four-sampled zero crossing asymmetry compensation algorithm provides 34% improvement of jitter performance, 50% reduction of compensation time and 2.0dB gain of SNR compared with other algorithms. Finally, the proposed systems combined with asymmetry compensator and DPLL are shown to provide improved performance of about 0.4dB, 2dB over the existing schemes by BER evaluation.

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Appropriate Timing of Surgery after Neoadjuvant Chemo-Radiation Therapy for Locally Advanced Rectal Cancer

  • Garrer, Waheed Yousry;Hossieny, Hisham Abd El Kader El;Gad, Zeiad Samir;Namour, Alfred Elias;Amer, Sameh Mohammed Ahmed Abo
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.9
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    • pp.4381-4389
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    • 2016
  • Background: Surgery is the corner stone for the management of rectal cancer. The purpose of this study was to demonstrate the optimal time of surgical resection after the completion of neoadjuvant chemo-radiotherapy (CRT) in treatment of locally advanced rectal cancer. Materials and Methods: This study compared 2 groups of patients with locally advanced rectal cancer, treated with neoadjuvant CRT followed by surgical resection either 6-8 weeks or 9-14 weeks after the completion of chemo-radiotherapy. The impact of delaying surgery was tested in comparison to early surgical resection after completion of chemo-radiotherapy. Results: The total significant response rate that could result in functional preservation was estimated to be 3.85% in group I and 15.4% in group II. Some 9.62% of our patients had residual malignant cells at one cm surgical margin. All those patients with positive margins at one cm were in group I (19.23%). There was less operative time in group II, but the difference between both groups was statistically insignificant (P=0.845). The difference between both groups regarding operative blood loss and intra operative blood transfusion was significantly less in group II (P=0.044). There was no statistically significant difference between both groups regarding the intra operative complications (P=0.609). The current study showed significantly less post-operative hospital stay period, and less post-operative wound infection in group II (P=0.012 and 0.017). The current study showed more tumor regression and necrosis in group II with a highly significant main effect of time F=61.7 (P<0.001). Pathological TN stage indicated better pathological tumor response in group II (P=0.04). The current study showed recurrence free survival for all cases at 18 months of 84.2%. In group I, survival rate at the same duration was 73.8%, however none of group II cases had local recurrence (censored) (P=0.031). Disease free survival (DFS) during the same duration (18 months) was 69.4 % for patients in group I and 82.3% for group II (P=0.429). Conclusions: Surgical resection delay up to 9-14 weeks after chemo-radiation was associated with better outcome and better recurrence free survival.

Energy Density Control for the Global Attenuation of Broadband Noise Fields (광대역 잡음의 전역 감쇠를 위한 에너지 밀도 제어)

  • Park, Young-Cheol;Yun, Jeong-Hyeon;Youn, Dae-Hee;Cha, Il-Whan
    • The Journal of the Acoustical Society of Korea
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    • v.15 no.2
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    • pp.21-32
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    • 1996
  • The performance of the energy density control algorithm for controlling a broadband noise is evaluated in a one-dimensional enclosure. To avoid noncausality problem of a control filter, which often happens in a frequency domain optimization, analyses presented in this paper are undertaken in the time domain. This approach provides the form of the causally constrained optimal controller. Numerical results are presented to predict the performance of the active noise control system, and indicate that imp개ved global attenuation of the broadband noise can be achieved by minimizing the energy density, rather than the squared pressure. It is shown that minimizing the energy density at a single location yields global attenuation results that are comparable to minimizing the potential energy. Furthermore, unlike the squared pressure control, the energy density control does not demonstrate any dependence on the error sensor location for this one-dimensional field. A practical implementation of the energy-based control algorithm is presented. Results show that the energy density control can be implemented using the two sensor technique with a tolerable margin of performance degradation.

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