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Active Prosthetic Valve Endocarditis: The Clinical Profile, Laboratory Findings and Mid-term Surgical Results (활동성 인공판막 심내막염: 임상 양상, 검사 소견 및 중기 수술 성적)

  • Kim, Hwan-Wook;Joo, Seok;Kim, Hee-Jung;Choo, Suk-Jung;Song, Hyun;Lee, Jae-Won;Chung, Cheol-Hyun
    • Journal of Chest Surgery
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    • v.42 no.4
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    • pp.447-455
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    • 2009
  • Background: Prosthetic valve endocarditis usually presents with clinical symptoms that are more severe than native valve endocarditis, and prosthetic valve endocarditis shows the spread of infection into the surrounding tissue as well as into the superficial endocardial layers. The postoperative prognosis is especially poor for valve re-replacement for the cases of active endocarditis that are unable to receive a full-course of pre-antibiotic therapy due to complications and the ensuing clinical aggravation. The aim of this study was to evaluate the clinical profiles, laboratory findings and mid-term surgical results of active prosthetic valve endocarditis. Material and Method: Among the 276 surgically treated infective endocarditis patients who were treated during the period from January 1998 to July 2008, 31 patients were treated for prosthetic valve endocarditis. Among these patients, 24 received surgical treatment for an 'active' state, and they were selected for evaluation. Result: The most frequently encountered symptom was a febrile sensation. Eight cases (33.3%) were accompanied by systemic thromboembolism, among which 5 cases (20.8%) had an affected central nervous system. 'Vegetations' were most commonly found on transesophageal echocardiography, and the 'Staphylococcus species' were the most frequent pathogens. There were 4 deaths in the immediate postoperative period, and an additional 4 patients died during the follow-up period (Mean$\pm$SD, 42.1$\pm$36.9 months). The cumulative survival rate was 79% at 1 year, 73% at 3 years, 66% at 5 year, and 49.5% at 7 years. Conclusion: The cases of active prosthetic valve endocarditis that were unable to receive a full course of preoperative antibiotics therapy generally have a poor prognosis. Nevertheless, early surgery and extensive resection of all the infected tissue is pivotal in improving the survival rate of patients with surgically treated active prosthetic valve endocarditis.

Altered Expression of ${\beta}_3$ Integrin on Sclerotic Aortic Valves in a Hypercholesterolemic Rabbit Model (고콜레스테롤혈증을 유발한 토끼의 대동맥 판막에서 ${\beta}_3$ Integrin 발현의 변화)

  • Park, Chan-Beom;Kim, Young-Du;Choe, Mi-Sun;Jin, Ung;Moon, Seok-Whan;Kim, Yong-Han;Kim, Chi-Kyung;Jo, Keon-Hyon;Kweon, Jong-Bum
    • Journal of Chest Surgery
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    • v.41 no.6
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    • pp.687-694
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    • 2008
  • Background: Although aortic valve sclerosis causes no significant hemodynamic alterations, it is associated with an increased risk of cardiovascular death and myocardial infarction. However, the role of ${\beta}_3$ integrin in aortic valve sclerosis remains unclear. Material and Method: Twenty male New Zealand rabbits were divided into two groups. Group 1 rabbits (n=10) received a normal chow diet, while group 2 (n=10) rabbits received a diet containing 1% cholesterol for 12 weeks. After the rabbits were euthanized, their aortic valves and ascending aortas were excised for analysis. Result: Total serum cholesterol ($2,148.3{\pm}1,012.5\;mg/dL$ versus $53.7{\pm}31.8\;mg/dL$, p<0.05), triglyceride ($240.4{\pm}218.3\;mg/dL$ versus $31.6{\pm}6.4\;mg/dL$, p<0.05), and low density lipoprotein (LDL)-cholesterol($2,065.3{\pm}960.9\;mg/dL$ versus $29.1{\pm}30.9\;mg/dL$, p<0.05) levels were significantly higher in the cholesterol diet group compared with the normal diet group. Myofibroblasts and macrophages were more highly expressed in the aortic valve leaflets of rabbits in the cholesterol diet group than of those in the normal diet group. A real-time polymerase chain reaction revealed decreased ${\beta}_3$ integrin mRNA levels in the hypercholesterolemic aortic valves and aortas. Conclusion: The present study shows that hypercholesterolemia induces aortic valve sclerosis. These findings suggest that alterations in ${\beta}_3$ integrin may playa role in the development of aortic valve sclerosis.

Midterm Results of the Bioprosthesis in Mitral Position (조직판막을 이용한 승모판 치환술의 중기 성적)

  • Cho, Hyun-Jin;Lee, Jae-Won;Jung, Sung-Ho;Je, Hyoung-Gon;Choo, Suk-Jung;Song, Hyun;Chung, Cheol-Hyun
    • Journal of Chest Surgery
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    • v.41 no.6
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    • pp.695-702
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    • 2008
  • Background: The choice between a bioprosthetic and a mechanical valve is an important decision in cardiac valve surgery, and the durability of the tissue valve is a major decision factor. We retrospectively evaluated the midterm results of bioprosthetic valve replacement in the mitral position. Material and Method: The subjects were all patients who had undergone mitral bioprosthesis replacement between July 1989 and August 200.7. Among the 216 patients, there were 236 surgical cases. The mean age was $63{\pm}15$ years, and the male to female ratio was 1 : 3. We retrospectively analyzed hospital and outpatient records such that the total follow-up duration amounted to 760.2 patient-years, and the mean follow-up duration was $41.9{\pm}40.7$ months (range $0{\sim}212$ months). Result: Early death occurred in 18 patients (8.3%), and 13 of these underwent concomitant cardiac procedures. The survival rate after 5 years was $79.9{\pm}3.5%$, and the survival rate after 8 years was $65.5{\pm}5.5%$, while freedom from structural valve deterioration (SVD) was $96.2{\pm}2.2%$ at 5 years and $85.9{\pm}5.3%$ at 8 years. Freedom from reoperation was $90.6{\pm}1.7%$ at 5 years and $90.4{\pm}4.2%$ at 8 years, while freedom from reoperation for SVD was $98.1{\pm}1.2%$ at 5 years and $92.3{\pm}4.1%$ at 8 years. On multivariate analysis of preoperative risk factors, small valve size (between 25mm and 27mm) was a significant risk factor for reoperation, and low LV ejection fraction (<40%) was a significant risk factor for SVD and mortality. Conclusion: Survival and freedom from reoperation for SVD in mitral bioprosthesis replacement had acceptable midterm results, but freedom from SVD Was relatively low. In particular, since SVD increased sharply at the eighth postoperative year, frequent follow-up and echocardiograms around that time will be helpful for the early detection of SVD. It will be necessary to conduct further studies involving long-term follow-up and more patients.

Determination of Flood Reduction Alternatives for responding to climate change in Gyeongan Watershed (기후변화 대응을 위한 경안천 유역의 홍수저감 대안 선정)

  • Han, Daegun;Choi, Changhyun;Kim, Duckhwan;Jung, Jaewon;Kim, Jungwook;Kim, Soo Jun
    • Journal of Wetlands Research
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    • v.18 no.2
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    • pp.154-165
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    • 2016
  • Recently, the frequency of extreme rainfall event has increased due to climate change and impermeable area also has increased due to rapid urbanization. Therefore, we ought to prepare countermeasures for flood reduction to reduce the damage. To consider climate change, the frequency based rainfall was calculated according to the aimed period(reference : 1971~2010, Target period I : 2011~2040, Target period II : 2041~2070, Target period III : 2071~2100) and the flood discharge was also calculated by climate change using HEC-HMS model. Also, the flood elevation was calculated by each alternative through HEC-RAS model, setting 5 sizes of drainage pumps and reservoirs respectively. The flood map was constructed using topographical data and flood elevation, and the economic analysis was conducted for reduction of flood damage using Multi dimension - Flood Damage Analysis, MD-FDA. As a result of the analysis on the flood control effect, a head of drainage pump was reduced by 0.06m up to 0.44m while it was reduced by 0.01m up to 1.86m in the case of a detention pond. The flooded area shrunk by up to 32.64% from 0.3% and inundation depth also dropped. As a result of a comparison of the Benefit/Cost index estimated by the economic analysis, detention pond E in period I and pump D in period II and III were deemed appropriate as an alternative for climate change. The results are expected to be used as good practices when implementing the flood control works considering climate change.

Study on the Community Structure of Benthic Macro-Invertebrates in Jangsu-cheon, an Urban Restoration Stream of Incheon City (인천시 도시복원하천 장수천의 저서성대형무척추동물의 군집구조에 관한 연구)

  • Song, Yeong-Ju;Ju, Yong-Don;Park, Bo-Sun;Kim, Jong-Myung;Kwon, Eun-Ho;Chae, Do-Young;Lee, Hee-Jo;Bae, Yang-Seop
    • Journal of Wetlands Research
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    • v.18 no.1
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    • pp.32-38
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    • 2016
  • The purpose of this study is to investigate the effects of the natural river conservation work and to find remedies for them, targeting Jangsu-cheon with high frequency of use by citizens among the rivers in Incheon Metroplitan City, Korea; for this, this study conducted investigations and analyses of Jangsu-cheon completed in December, 2008. As a result of investigating 3 spots for the water system of Jangsu-cheon over a total of 3 years (2009, 2010, 2014), it was found that benthic macro-invertebrates of a total of 3 phyla, 5 classes, 11 orders, 26 families, 56 species, and 980 specimens were distributed there. When they were analyzed by year, 18 families and 30 species in 2009, right after the natural river conservation work, and 22 families and 37 species in 2010, 2 years after the work, were found, with 7 species increasing in number; after that, as a result of the investigation in 2014, 22 families and 38 species were found, which tells the river has entered the stabilization stage since the recovery in 2010.Therefore, this study could identify: the water environment of the river was improved due to the natural river conservation work for Jangsu-cheon; in addition, Jangsu-cheon showed good ecological environment due to the continuous maintenance of the good wetlands in Incheon Grand Park in the upper area of the river; and the natural river conservation work of Jangsu-cheon created positive effects.

Changes of Physical Structure of Hangang(Riv.) in Seoul City Area (서울시 구간 한강의 물리적 구조 변화에 관한 연구)

  • Hong, Sukhwan;Yeum, Junghun;Han, Bongho
    • Journal of Wetlands Research
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    • v.19 no.4
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    • pp.403-408
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    • 2017
  • This study aims to set up the basic data to manage the waterfowl habitat through the analysis of the changes of physical structure according to the time series of Hangang(Riv.) as water birds' habitat. Study area was 41.5km in length from Paldang bridge to Hangju bridge. during total length of 497.52km and horizontal boundary was based on the protected lowland in year 1975. As the analysis result of land use from the center of water to adjacent road to the river, ratio of year 1975 was in order of sedimentary land(22.7%), surface water(20.7%), built-up area(16.9%), field(16.2%), paddy field(15.9%), and afterwards most of the areas were changed through the construction of arterial highway and submerged weir in order to use Hangang(Riv.). In year 1985, the area ratio of protected lowland(57.8%) and surface water(32.8%) dramatically increased. After construction of river bank the recreational areas continually increased and relatively natural areas decreased. In year 2005, the area ratio of protected lowland was enlarged to 57.6% and surface water also to 33.3%. While the length of both riversides and naturalness decreased by 10.9%, 91.5% respectively in year 2005 compared to year 1975, the depth of water increased by 1.46m. Comprehensively, the flow of changes by physical structure in Hangang(Riv.) for 30 years was divided into two periods. The main characteristics in the first period were decrease of riverside area and enlargement of the surface water through the massive construction before middle of year 1980, and afterwards revetments were intensively artificialized with changes of land use for amusement area. In terms of water fowl habitat, Hangang(Riv.) which previously had various types of habitat condition was changed into simplified habitat for few of species, and the active improvement apporach was needed for habitat diversity.

End-use analysis of household water by metering (가정용수의 용도별 사용량 조사 및 원단위 분석)

  • Kim, Hwa-Soo;Lee, Doo-Jin;Kim, Ju-Whan;Kim, Jung-Hyun;Jung, Kwan-Soo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2008.05a
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    • pp.869-877
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    • 2008
  • The purpose of this study is to investigate the trends and patterns of variou kind of water uses in a household by metering in Korea. Water use components are classified by toilet, washbowl, bathing, laundry, kitchen, etc. Flow meters are installed in 146 household selected by sampling in all around Korea. The data are gathered by web-based data collection system from the year 2002 to 2006, considering pre-investigated data such as occupation, revenue, family members, housing types, age, floor area, water saving devices, education, etc. Reliable data are selected by upper fence method for each observed water use component and statistical characteristics are estimated for each residential type to determine liter per capita per day. Estimated domestic per capita day show an indoor water use with the range from $150{\ell}pcd$ to $169{\ell}pcd$ for each housing type as the order of high rise apartment, multi-house, and single house. As the order of consuming amount among water use components, it is investigated that toilet($38.5{\ell}pcd$) is the first, and the second is laundry water($30.8{\ell}pcd$), the third is kitchen($28.4{\ell}pcd$), the fourth is bathtub($24.7{\ell}pcd$), the next is washbowl($15.4{\ell}pcd$). The results are compared with water uses in U.K. and U.S. As life style has been changed into western style, pattern of water use in Korea is tend to be similar with the U.S. water use pattern. Compared with the surveying results by Bradley, on 1985. Thirty liter of total use increased with the advancement of economic level, and a little change of water use pattern can be found. Especially, toilet water take almost half part of total water use and laundry water shows lowest as 11% in surveying at the year of 1985. But, this study shows that 39 liter, 28% of toilet water, has been decreased by the spread of saving devices and campaign. It is supposed that the spread large sized laundry machine make by-hand laundry has been decreased and water use increased. Unit water amount of each end-use in household can be applied to design factor for water and wastewater facilities, and it play a role as information in establishing water demand forecasting and conservation policy.

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The Effect of Sex Education Using Multimedia Program - Focusing on Elementary School Sixth-Grade - (멀티미디어 프로그램을 활용한 성교육의 효과 - 초등학교 6학년을 중심으로 -)

  • Back, Un-Seck;Park, Young-Soo
    • The Journal of Korean Society for School & Community Health Education
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    • v.1 no.1
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    • pp.83-93
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    • 2000
  • The purpose of this study were to suggest the method of sex education by designing and implementing multimedia program about sex education, to search the efficiency between a teaching using multimedia program and a teaching of traditional method. To put above aims into practice, these were required : 1. are there any differences in the alteration of sex attitude according to teaching methods. 2. are there any differences in the completion of sex knowledge according to teaching methods. 3. are there any differences in the alteration of sex attitude according to learning level and teaching methods. 4. are there any differences in the completion of sex knowledge according to learning level and teaching methods. 5. are there any differences in the alteration of sex attitude according to sex and teaching methods. 6. are there any differences in the completion of sex knowledge according to sex and teaching methods. To carry out a reseach for this purpose, the subjects for this study were 160 sixth grade students from 2 elementary schools in Pu-Chun, Kyung Ki. The tools for study were two kind of questionnaires: sex knowledge test, sex attitude test. Each test consists of 20 items. Collected data was analysed with t-test by means of SPSS program. The main results of this study are as follow: 1. The Alteration of sex attitude according to teaching methods. There was a significant difference among teaching methods(P<.001). a teaching using multimedia program was more efficient than a teaching of traditional method in the alteration of sex attitude. 2. The Completion of sex knowledge according to teaching methods. There was a significant difference among teaching methods(P<.001). a teaching using multimedia program was more efficient than a teaching of traditional method in the completion of sex knowledge. 3. The Alteration of sex attitude according to learning level and teaching methods. There was a significant difference among teaching methods in the superior class. a teaching using multimedia program was more efficient than a teaching of traditional method in the alteration of sex attitude(P<.001). However, there was not a significant difference among teaching methods in the inferior class(P>.05). 4. The Completion of sex knowledge according to learning level and teaching methods. There was a significant difference among teaching methods in the superior class. a teaching using multimedia program was more efficient than a teaching of traditional method in the completion of sex knowledge(P<.001). Also, there was a significant difference among teaching methods in the inferior class. a teaching using multimedia program was more efficient than a teaching of traditional method in the completion of sex knowledge(P<.001). 5. The Alteration of sex attitude according to sex and teaching methods. There was a significant difference among teaching methods in the man class. a teaching using multimedia program was more efficient than a teaching of traditional method in the alteration of sex attitude(P<.01). However, There was not a significant difference among teaching methods in the woman class(P>.05). 6. The Completion of sex knowledge according to sex and teaching methods. There was a significant difference among teaching methods in the man class. a teaching using multimedia program was more efficient than a teaching of traditional method in the completion of sex knowledge(P<.001). Also, there was a significant difference among teaching methods in the woman class. a teaching using multimedia program was more efficient than a teaching of traditional method in the completion of sex knowledge(P<.05).

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Teachers' Understanding of Environment around Schools and Actual Survey in Prejudical Business in Taegu City (대구지역(大邱地域) 학교주변(學校周邊) 환경(環境)에 대한 교사(敎師)의 인식(認識)과 유해업소(有害業所) 실지조사(實地調査))

  • Yang, Myung Sook;Kim, Sang Soon
    • Journal of the Korean Society of School Health
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    • v.7 no.1
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    • pp.45-55
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    • 1994
  • The purpose of this study is to contribute to improvement of educational environment by analysing all problems related to environment around the school. To accomplish this purpose, this study was carried out by examining the problems in controlling the areas required for cleanup with 220 teachers in charging the cleanup duties of the primary and secondary schools in Taegu between June 1 and July 15, 1993 and by actually surveying the prejudical business stores around 72 primary schools between August 10 and September 20, 1993. Although most teachers answered to the questionnaires that it is necessary to cleanup the bad environment around the school, the duties of its cleanup tend not to be considered as an important matter. The teachers considered that the most prejudical business store around the school is totally the game room, and in such order as comic books' store, liquor selling shop and causing noise and pollution. 57.3% of total respondents answered that the present cleanup movements have resulted in failure mostly because of both supervising authorities' careless promotion and store owners' excessive commercial transactions. The result of actual survey in environmental and sanitary cleanup area around 72 primary schools showed that the greatest number of 1,258 prejudical stores was the video tapes shop, and then in such order as lodgings, and game rooms, while the number of prejudical store by the schools was 17.5 stores per school on the average which showed a various distribution from zero to 77 places. In general, these prejudical stores were mainly located around the schools in Jung-gu and Seo-gu areas. In addition, it was shown that the more the number of students, the more the number of the prejudical stores. In order to improve the environment around the school, it is necessary to strictly carry out the zoning system relating to the usage of land, to strongly restrict the stores without permit and abnormal stores and to establish the basis asking the city development authorities to go through the environmental evaluation. Moreover, it is absolutely required to make efforts to establish the national right sense of education, and to closely cooperate with the related authorities.

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Comparison of the measurement methods of soil water content by error analysis (토양수분(土壤水分) 함량(含量) 측정방법별(測定方法別) 오차분석(誤差分析)에 의(依)한 비교(比較))

  • Eom, K.C.;Ryu, K.S.;Um, K.T.
    • Korean Journal of Soil Science and Fertilizer
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    • v.21 no.4
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    • pp.367-372
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    • 1988
  • A series of field experiment was conducted to find out error range and to compare precision based on error analysis of soil water content measured with gravimetric, surface & depth neutron and gypsum block methods in a sandy loam soil. The error of soil water content measured with gravimetric (core-sampling), surface and depth neutron method showed quardratic curve, whereas that with gypsum block was exponential curve in relation to soil water content. Within the range of volumetric soil water content from 11 to 33%, the error of soil water content measured with gravimetric, surface neutron, depth neutron and gypsum block method was ranged from 0.28 to 3.49%, 0.71 to 2.63%, 0.52% to 1.01% and 0.05 to 21.89%, respectively. The error of soil water content measured with depth neutron method was lower than those of other methods, when the soil water content was more than 14% in sandy loam soil. The relative number of replicates of soil water measurement for surface neutron, depth neutron and gypsum block method to attain same precision for gravimetric method was 0.6-1.7, 0.07-0.8 and 0.1-125, respectively.

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