• The Korean Journal of Physiology
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• v.23 no.1
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• pp.51-66
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• 1989

Mammalian cardiocytes secrete atrial natriuretic peptides (ANPs) into plasma, which cause marked natriuresis, diuresis, vasorelaxation and inhibition of hormone secretions. Aging influences the ability of the kidney both to conserve and to excrete sodium; i.e., in old animals, the excretory capacity of sodium is reduced and the time required to excrete sodium load is prolonged. Therefore, it is possible that animals differing in ages may respond differently to ANP. In the present study, we determined whether the renal, hormonal and vascular effects of ANP may be influenced by aging in conscious rabbits. The plasma renin concentration decreased with aging but plasma ANP concentration was significantly lower only in 24-month-old rabbits. Plasma aldosterone concentration and atrial ANP content did not change by aging. In 1-month-old rabbits, ANP (atriopeptin III, 3 ug/kg) administered intravenously caused hypotension and decreased in plasma renin and aldosterone concentrations, but did not cause diuresis and natriuresis. In 2 to 5 month-old rabbits, ANP caused hypotension, decreases in Plasma renin and aldosterone concentrations and marked renal effects. However, in 24-month-old rabbits, all the above effects of ANP was blunted. With hydration of physiological saline at a rate of 15 ml/kg/h for 2hr, urine volume and glomerular filtration rate did not change but the electrolyte excretion as well as fractional excretion of sodium significantly increased. The plasma concentrations of active renin and aldosterone were decreased but plasma inactive renin and ANP concentrations were increased. The changes in renal function and plasma level of hormone showed no differences in different ages. These results suggest that the peripheral vascular receptors to ANP may develop earlier than those in the kidney, and the attenuated vascular and renal responses to ANP in the old age may be due to age-related modifications in renal function and blood vessel.

• Journal of Family Resource Management and Policy Review
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• v.13 no.3
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• pp.137-155
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• 2009

The purpose of this study is to analyze the effects of the degree of preparation for old age and perception of successful aging on the life satisfaction of middle-aged women. The participants in this study were 300 women ranging in age from 35 years to 65years who reside in Seoul, Gyeonggi-do, and other cities. Two hundred eight self-reported questionnaires were used for final analysis by SPSS WIN14. The major results of this study were as follows: First, there were differences in the degree of preparation for old age of middle-aged women by age, academic career, income, area, and religion. Second, there were differences in self-efficacy in the perception of successful aging by academic career, an income, and area. Third, there were differences in the degree of life satisfaction of middle-aged women by academic career and income. Finally, the most effective variables on the degree of life satisfaction were the degree of preparation for old age, perception of successful aging, and income. Consequently, to improve the life satisfaction of middle-aged women, social groups, local self-governments, and the government have to educate women on economic management for preparation for old age and human relationship progress programs, as well as promote healthy leisure cultures.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.12
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• pp.1645-1656
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• 2010

This study was conducted to investigate the effects of strain on broiler performance, and age at slaughter and postchilling (PC) aging time on meat quality traits. A total of 500 one-day-old chicks (250 Hubbard classic and 250 Lohman) were reared under commercial conditions. Half of the broiler birds from each strain were slaughtered at 32 days and the other half at 42 days old. At each processing day, 168 carcasses were randomly selected (84 Hubbard and 84 Lohman) and divided into groups of 28 carcasses within each strain, and aged for 0, 4 and 24 h after chilling. Average weekly body weight was comparable between strains. Feed conversion ratio was higher (p<0.05) for the Hubbard strain during the second and third week of age. Initial carcass pH was significantly (p<0.05) affected by age where younger birds (32-d-old) had lower pH values than older (41-d-old) birds. Breast temperature was higher (p<0.001) for Lohman than Hubbard at 0, 2 and 4 h of PC. Younger birds had a lower breast temperature (p<0.001) at all measured times of PC. Thaw loss, cook loss and water holding capacity were not significantly affected by strain, age or aging time. Lohman strain had more tender meat (p<0.05) than Hubbard strain, and tenderness was improved with the increase of broiler age and aging time. Meats from Hubbard were lighter and less red than those from Lohman strain where younger birds had darker color. In conclusion, strain, age at slaughter and PC aging duration are critical to breast meat quality characteristics, and 4 h of aging are required before deboning in order to obtain more tender fillets.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.8
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• pp.1497-1505
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• 2010

The present study was performed to investigate the effect of aging on muscular activity of older subjects under the condition of fixed load muscle contraction. SEMG signals were recorded from old (46 women) and young (45 women) groups performing sustained isometric elbow flexion contraction with a fixed load during 30 seconds. Linear regression and mean square error (MSE) analysis with four characteristic variables (ARV, RMS, MDF, MNF) were used to compare the age-related difference (of local muscle fatigue and fluctuation of the amplitude and frequency) in the SEMG signal. The main results can be summarized as follows: During sustained muscle contraction with a fixed load: i) the MSE values of amplitude (ARV, RMS) and frequency (MDF, MNF) variables were more than 30% higher for the young than for the old adults; ii) the measures of local muscle fatigue (slope of the MDF and MNF) indicated greater fatigue in the old; and iii) the rate of increase of the SEMG amplitude was higher for the young than the old.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2023.05a
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• pp.275-276
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• 2023

In order to prevent disaster risks caused by building aging in advance, the prevailing opinion is that it is urgent to actively improve systems such as mandatory safety inspections, and to calculate risks and develop safety management systems due to building aging. The need for systematic risk management continues to be emphasized in the process of safety inspection and repair of old buildings, but the risk management and safety management techniques of each construction entity have not been established in practice. Accordingly, this study aims to analyze the vulnerability factors of aging buildings and provide basic data on the development of a risk rating calculation model for old buildings and the efficiency of safety management systems in the future.

• KIEAE Journal
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• v.12 no.4
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• pp.47-57
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• 2012

The purpose of this study is to develop an aging friendly guideline aging friendly outdoor exercise environment in Universal design aspect. The aim for this guideline is to suggest a creative method to cope with forthcoming aging society and meet the various demands of all park users. Documentary survey and field survey were used to extract notion of universal design and aging friendly design; based from the extracted notions three types of exercise environment were suggested, Small scale, Medium scale and Large scale. The significant of this guideline is as fallow: First, negative aspects of aging friendly design can be eliminated by adopting universal design; therefore the guideline can have social integration aspect. Second, reflected needs of residents can be suggested on the guideline; and it was extracted from documentary survey, PPP UD checklist and field survey. Third, classifying universal design and aging friendly design in one guideline can enhance ability to manage various composition of population. Fourth, by studying young child and old people's likeness and parallel resemblance, design guideline for forthcoming aging society can be suggested. Fifth, from three developed exercise environments, the guideline can be applied into different conditions of location. Sixth, canopy type design model can be very useful for old people.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.22 no.1
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• pp.27-39
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• 1996

Recently, in vitro stratum curneum model was a useful tool to evaluate the skin condition such as tranespidermal water loss, skin hydration and etc.. In this study to evaluate the alteration of SC with aging in hairless mouse, we measured TEWL using in vitro SC model, SC lipid, and outer corneocytes area. Although the total SC lipid was rich about 30% in 8 week old mouse compared with that of 82 week old mouse, the TEWL values were higher in the former than that of the latter. The outer corneocytes area was 559 $\pm$ 65 $mu extrm{m}$2 in 8 week old mouse and 755 $\pm$ 56 ${\mu}{\textrm}{m}$2 in 82 week old mouse. So the barrier function was reinforced with aging. This result suggested that the reinforced barrier function is one of the defense systems against the outer enviornment and the decreased skin function with aging.

• Genomics & Informatics
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• v.4 no.1
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• pp.23-32
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• 2006

In order to investigate the molecular basis of the aging process in brain, we have employed high-density oligonucleotide microarrays providing data on 10,108 gene clusters to define transcriptional patterns in three brain regions, cerebral cortex, cerebellum, and hippocampus. Comparison of the expression patterns between young (6-week-old) and aged (17-month-old) C57BL/6 male micerevealed that about ten percent (1098) of the genes showed a significant change in the expression level in at least one of the three tissues. Among them, 23 genes were upregulated and 62 genes were downregulated in all three tissues of the old mice. The number of genes upregulated exclusively in hippocampus (337) was much larger compared to other tissues. Gene ontology-based analysis showed the genes related with signal transduction or molecular transports are more likely to be upregulated than downregulated in the aging process of hippocampus. These data may provide some useful means for elucidating the molecular aspect of aging in hippocampus and other regions in brain.

• Journal of the Korean Home Economics Association
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• v.42 no.7
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• pp.145-164
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• 2004

The purpose of this study is to understand how late middle-aged women in our society view and adapt to “aging”. This is a crucial step forward linking two stages, the growing young age and the declining old age, which eventually improves the qualify of life in old a9e. This qualitative study used Personal narratives extracted from tape-recorded interviews of 20 late middle-aged women in their fifties and analyzed key experiences of late middle-aged women in their transition to old age. Participants were observed to perceive not only many limitations but also alternative potentialities. First, the major challenges due to the closing young era were ‘physical declines’, including health problems and wrinkles, and ‘leaving children’. Second, the potentialities to start a new era also could be found. Many participants found themselves to be generous enough to assist others in need. In addition, they looked to adapt to new challenges. It was likely that the many adversities that they had faced made them resilient. These results show that late middle-aged women were actively negotiating with themselves and their surroundings in order to overcome their losses, maintain their potentialities, and, in the process, acknowledge their impending old age for better preparation.

• Management & Information Systems Review
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• v.16
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• pp.139-159
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• 2005

In many countries the demographics clearly informs us that an aging population represent a serious problem. To this extent senior citizens welfare does matter it has developed into a public debate and genuine concern. it seems that the social issues are focused on how the socity views the social welfare policies. In a modern welfare state where the emphasis lies in pursing a high standard of living and thereby high quality of life. This does not cover the very well the old people in society, but the government clearly carries an obligation to look after and care for the retired & old people in the society. This obligation the social and economic impact that an old person faces as he/she grows old. it is important ensure that their lives carries a meaning and that they as a group will not be estranged from the mainstream of society just because they are considered to be part of the aging population. The key issues that must be addressed are 1) The impact of reduced spending power from less income. a lower income stream; 2) increasing health problems and costs; 3) the natural degradation of ones physical & mental powers; 4) and thereby an isolation from the public in general. So clearly the social policy related to the old people in society should be developed with the consent of what they believe is important to them. To ensure their minimum income level that a beneficiary of an old person's pension will receive, the monthly pension should be reflected by the official price index and be adjusted accordingly. by making the job market open for the senior citizens, expending the mandatory retirement age, give companiesincentives to hire senior citizens, there maybe an opportunity to extend to the aging population the possibility to continue to participate in the society at large.