• Asian-Australasian Journal of Animal Sciences
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• 제33권3호
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• pp.515-524
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• 2020

Objective: Human mesenchymal stromal cells (MSCs) exhibit variable differentiation potential and can be divided accordingly into distinct subpopulations whose ratios vary with donor age. However, it is unknown whether the same is true in pigs. This study investigated MSC subpopulations in miniature pig and compared their characteristics in young (2 to 3 months) and adult (27 to 35 months) pigs. Methods: Osteogenic, chondrogenic, and adipogenic capacity of isolated MSCs was evaluated by von Kossa, Alcian blue, and oil red O staining, respectively. Cell surface antigen expression was determined by flow cytometry. Proliferative capacity was assessed with the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Expression of marker genes was detected by quantitative real-time polymerase chain reaction. Results: Porcine MSCs comprised cells with trilineage and bilineage differentiation potential (tMSCs and bMSCs, respectively) and non-differentiating stromal cells (NDSCs). The tMSC and bMSC fractions were smaller in adult than in young pigs (63.0% vs 71.2% and 11.6% vs 24.0%, respectively, p<0.05); NDSCs showed the opposite trend (25.4% vs 4.8%; p<0.05). Subpopulations showed no differences in morphology, cell surface antigen expression, or proliferative capacity, but octamer-binding transcription factor 4 (OCT4) expression was higher in tMSCs than in bMSCs and NDSCs (p<0.05), whereas sex determining region Y-box 2 (SOX2) expression was higher in tMSCs and bMSCs than in NDSCs (p<0.05). Aging had no effect on these trends. Conclusion: Porcine MSCs comprise distinct subpopulations that differ in their differentiation potential and OCT4 and SOX2 expression. Aging does not affect the characteristics of each subpopulation but alters their ratios.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 추계 학술발표회 제20권2호
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• pp.537-540
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• 2008

터널이 장대화됨에 따라 국내외 대규모 터널 화재 발생 빈도가 점차 증가하고 있다. 최근 터널 내유조차의 폭발로 터널 내부의 최고 온도가 1,350$^{\circ}$C까지 상승한 것이 보고된 바 있고 이로 인해 인명피해 뿐 아니라 심각한 구조적 손상을 입기도 하였다. 이에 내화콘크리트 및 내화모르타르를 사용하여 터널의 대규모 화재 시 콘크리트 구조물의 내화성능을 향상시키기 위한 연구가 진행되고 있다. 본연구는 내화모르타르를 사용함으로써 터널의 내화성능 향상을 도모하고 이를 현장에서 적용하기 위한 기초연구로서, 현 연구단계에서는 내화시험에 앞서 강도 시험 및 작업성 시험 등 기본적 물성시험을 실시하여 내화모르타르의 기초적인 역학 특성을 고찰하였다. 시험결과를 통하여 내화모르타르의 기본적인 역학 특성을 파악하였으며 또한 굳지 않은 모르타르의 Flow시험을 실시함으로써 현장 적용성및 양호한 작업성을 확인하였다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2005년도 춘계학술대회 논문집
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• pp.213-221
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• 2005

광양항은 부산항과 더불어 우리나라 컨테이너 화물 처리 Two Port System의 한축으로 개발 중인 동북아 중심항만(Hub Port)으로서 향후 2011년까지 총 33개의 컨테이너 선석 등이 개발 추진 중에 있어 해상교통량이 급격히 증가하고 있으며, 또한 거대선 ${\cdot}$ 위험화물운반선 ${\cdot}$ 고속여객선의 통항이 빈번하여 대형사고의 발생우려가 상존하고 있다. 본 연구에서는 광양항을 이용하는 선박의 입출항 항로 등에 대한 해상교통환경을 면밀히 분석${\cdot}$평가하고, 통항로 및 항행보조시설 등의 적정성 검토를 통하여 미래 지향적이고 안전한 해상교통환경을 조성하기 위한 체계적이고 종합적인 항로를 설정한다.

• 대한의생명과학회지
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• 제12권3호
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• pp.241-247
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• 2006

To evaluate an effect of pathological liver damage on the cyclohexane (CH) metabolism, rats were pretreated with 50% carbon tetrachloride $(CCl_4)$ dissolved in olive oil (0.1ml/100g body weight) 10 or 17 times intraperitoneally at intervals of every other day. To these liver damaged animals, CH (a single dose of 1.56g/kg body weight, i.p.) was administered at 48hr after the last injection of $CCl_4$. The CH metabolites; cyclohexanol (CH-ol), cyclohexane-l,2-diol (CH-l,2-diol) and cyclohexane-l,4-diol (CH-l,4-diol) and cyclohexanone (CH-one) were detected in the urine of CH treated rats. After CH treatment, the serum levels of CH-ol and CH-one were remarkably increased at 4 hr and then decreased at 8hr in normal group. Whereas in liver damaged rats, these CH metabolites were higher at 8hr than at 4hr. The excretion rate of CH metabolites trom serum into urine was more decreased in liver damaged animals than normal group, with the levels of excretion rate being lower in $CCl_4$ 17 times injected animals than 10 times injected ones. It was interesting that the urinary concentration of CH metabolites was generally more increased in liver damaged animals than normal ones, and the increasing rate was higher in $CCl_4$ 17 times injected rats than 10 times injected ones. Taken all together, it is assumed that reduced urinary excretion rate of CH metabolites in liver damaged rats might be resulted from deteriorated hepatic and renal blood flow, and an increased urinary excretion amount of CH metabolites in liver damaged rats might be caused by reduced expiration amount of the metabolites due to lung damage.

• 해양환경안전학회지
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• 제11권2호
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• pp.1-8
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• 2005

현행 목포항의 항로는 달리도 등대 수역과 고하도 만곡부 지점을 대각도로 변침해야 함으로 국$\cdot$내외의 항로선계지침을 충족하지 못하고 있다. 또한 항로 주변에 천소가 존재하고 제2항로의 신설로 인한 통항선박의 항법문제, 항로표지의 재배치 및 신실 등이 필요하다. 따라서 본 연구에서는 목포항 접근수역에 대한 자연환경, 해양사고, 해상교통량 및 해상교통흐름실태조사, 어업현황 등을 조사$\cdot$분석하고, 전문가 및 이용자에 대한 설문조사 및 국내외 항로설계지침과의 적절성 등을 검토하여 개선안을 도출하고자 한다. 또한 개선안에 대한 해상교통류시뮬레이션 및 선박조종시뮬레이션을 실시하여 타당성을 검증한다.

• Tribology and Lubricants
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• 제34권3호
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• pp.75-83
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• 2018

Microturbomachinery (< 250 kW) using gas foil bearings can function without oil lubricants, simplify rotor-bearing systems, and demonstrate excellent rotordynamic stability at high speeds. State-of-the-art technologies generally use bump foil bearings or leaf foil bearings due to the specific advantages of each of the two types. Although these two types of bearings have been studied extensively, there are very few studies on leaf-bump foil bearings, which are a combination of the two aforementioned bearings. In this work, we illustrate a simple mathematical model of the leaf-bump foil bearing with leaf foils supported on bumps, and predict its static and dynamic performances. The analysis uses the simple elastic model for bumps that was previously developed and verified using experimental data, adds a leaf foil model, and solves the Reynolds equation for isothermal, isoviscous, and ideal gas fluid flow. The model predicts that the drag torques of the leaf-bump foil bearings are not affected significantly by static load and bearing clearance. Due to the preload effect of the leaf foils, rotor spinning, even under null static load, generates significant hydrodynamic pressure with its peak near the trailing edge of each leaf foil. A parametric study reveals that, while the journal eccentricity and minimum film thickness decrease, the drag torque, direct stiffness, and direct damping increase with increasing bump stiffness. The journal attitude angle and cross-coupled stiffness remain nearly constant with increasing bump stiffness. Interestingly, they are significantly smaller compared to the corresponding values obtained for bump foil bearings, thus, implying favorable rotor stability performance.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2002년도 제5회 압출 및 인발가공 심포지엄
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• pp.43-49
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• 2002

A7003 alloy has characteristics of their excellent weldability, high corrosion resistance and superior plastic working however the broadening of application for the alloy has been hampered by the lower extrudability associated by Mg content. For improvement of extrudability and enhanced recovery efficiency during Al scrap recyeling, it has been generally practiced to reduce Mg content in A7003 alloy. Therefore, it is necessary to investigate the influence of Mg content on mechanical strength and extrudability of A7003 alloy. For efficient material processing which has small amounts, life cycle assessment in material processing(MLCA) is evaluated. The quantitative analysis of energy requirements and $CO_2$ emission for production of A7003 extruded bar are estimated with different Mg content and billet pre-heating process (heating source by light oil or LPG). In particular, the estimation of energy requirements was performed within shipping and gating range (except the mining and extraction stages)to investigate the influence of the variables on energy requirements and $CO_2$ emission in detail. As Mg content increased, the flow stress and the extrusion pressure for A7003 alloy increased. It has been thought that an increment in extrusion pressure with increasing Mg content is caused by the solid solution hardening of Mg atoms in the matrix and increment in volume fraction of intermetallic compound, $Mg_2Si$. The extrudability and the tensile strength are equal to, or above that of conventional A 7003 alloy even the content of Mg varied from $1.1wt.\%\;to\;0.5wt.\%$ alloy. This means that minimizing the content of Mg in A7003 alloy can enhance recovery efficiency during Al scrap recycling. It can be quoted that rather than Mg content energy source for billet heating is a prime factor to determine the atmospheric $CO_2$ emission.

• 대한기계학회논문집B
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• 제28권12호
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• pp.1535-1548
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• 2004

Condensation heat transfer experiments were conducted with the oblong shell and plate heat exchanger without oil in a refrigerant loop using R-l34a, R-407C and R-410A. An experimental refrigerant loop has been developed to measure the condensation heat transfer coefficient h$_{r}$ and frictional pressure drop $\Delta$p$_{f}$ of the various refrigerants in a vertical oblong shell and plate heat exchanger. The effects of the refrigerant mass flux(40∼80kg/$m^2$s), average heat flux(4∼8kW/$m^2$), refrigerant saturation temperature(30∼4$0^{\circ}C$) and vapor quality of refrigerants on the measured data were explored in detail. Similar to the case of a plate heat exchanger, even at a very low Reynolds number, the flow in the oblong shell and plate heat exchanger remains turbulent. A comparison of the performance of the various refrigerants revealed that R-410A had the highest heat transfer performance followed by R-l34a, and R-407C had the lowest performance of the refrigerants tested. The pressure drops were also reported in this paper. The pressure drops for R-410A were approximately 45% lower than those of R-l34a. R-407C had 30% lower pressure drops than R-l34a. Experimental results were compared with several correlations which predicted condensation heat transfer coefficients and frictional pressure drops. Comparison with the experimental data showed that the previously proposed correlations gave unsatisfactory results. Based on the present data, empirical correlations of the condensation heat transfer coefficient and the friction factor were proposed.tor were proposed.sed.

• 한국마린엔지니어링학회:학술대회논문집
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• 한국마린엔지니어링학회 2005년도 전기학술대회논문집
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• pp.189-194
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• 2005

The evaporation heat transfer and pressure drop of $CO_2$ in a small diameter tube was investigated experimentally. The experiments were conducted without oil in a closed refrigerant loop which was driven by a magnetic gear pump. The main components of the refrigerant loop are a receiver, a variable-speed pump, a mass flow meter, a pre-heater and evaporator(test section). The test section was made of a horizontal stainless steel tube with the inner diameter of 4.57 mm, and length of 4 m. The experiments were conducted at mass flux of 200 to 700 $kg/m^2s$, saturation temperature of $0^{\circ}C$ to $20^{\circ}C$, and heat flux of 10 to 20 $kW/m^2$ . The test results showed the evaporation heat transfer of $CO_2$ has great effect on more nucleate boiling than convective boiling. The evaporation heat transfer coefficients of $CO_2$ are highly dependent on the vapor quality, heat flux and saturation temperature. The evaporation pressure drop of C02 are highly dependent on the mass flux. In comparison with test results and existing correlations, correlations failed to predict the evaporation heat transfer coefficient and pressure drop of $CO_2$, therefore, it is necessary to develop reliable and accurate predictions determining the evaporation heat transfer coefficient and friction pressure drop of $CO_2$ in a horizontal tube.

• 한국산학기술학회논문지
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• 제14권6호
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• pp.2588-2595
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• 2013

기존의 유압식 엘리베이터에서 엘리베이터 카의 하강행정 동안 손실 되는 유압 에너지를 회수하여 재사용하기 위하여 개발한 유압식 엘리베이터용 하이브리드 형 에너지 저감 장치에 대한 성능 특성에 관하여 연구하였다. 회수된 에너지는 축전지에 저장하여 재사용할 수 있도록 구성되어 있으며, 엘리베이터의 구동 조건에 따른 에너지 저감장치의 출력 특성, 효율 및 에너지 회수율 등에 관하여 실험을 통하여 규명하고자 하였다. 본 연구의 결과들은 하강행정 동안 버려지는 에너지의 회수율이 최대 약 54%로 에너지 저감 장치의 압력, 유량, 출력 전압과 전류, 효율 및 에너지 회수율 등과 같은 성능 특성들이 안정적이고 양호하다는 것을 보여주고 있으며, 본 연구를 통하여 유압식 엘리베이터의 에너지 저감 장치를 통하여 하강행정 동안 회수된 에너지를 재사용하데 매우 유용하며, 상용화 가능성이 충분하다는 것을 확인하였다.