• Title/Summary/Keyword: Oh Kyu-won

Search Result 576, Processing Time 0.026 seconds

Compositions of Astragali Radix and Angelicae Radix by DPPH Radical Scavenging Activity (당귀(當歸)와 황기(黃芪)의 배합 변화가 DPPH 자유기 소거에 미치는 영향 연구)

  • Kang, Soon-Ah;Oh, Myung-Sook;Kim, Do-Rim;Kang, Ji-Ung;Kim, Won-Nam;Park, Eun-Hwa;Chang, Mun-Seog;Park, Seong-Kyu
    • The Korea Journal of Herbology
    • /
    • v.21 no.1
    • /
    • pp.17-24
    • /
    • 2006
  • Objectives : This study was conducted to compare antioxidant activity of ratio-related Angelicae Radix and Astragali Radix compositions by DPPH radical scavenging activity. Methods : The species of Angelicae Radix was compared as Angelica gigas, A. sinensis and A. acutiloba. Then various compositions of Angelicae Radix with Astragali Radix were prepared with different ratio. Diphenyl-picryl-hydrazyl (DPPH) radical scavenging activity was measured after 10, 20 and 30 minutes. Each extracts were tested by 1, 5, 10, 50, 100, 500 and 1,000 ${\mu}g/ml$ concentrations. Results : The results showed that Angelica gigas, A. sinensis and A. acutiloba scavenged DPPH radical with 66.8, 61.7 and 56.7% in 1,000 ${\mu}g/ml$ concentration, respectively. According to this result, Angelicae Radix and Astragali Hadix compositions with 100:0, 10:1, 5:1, 3:1, 1:1, 1:3, 1:5, 1:10 and 0:100 ratio were scavenged DPPH radical with 56.3, 49.9, 61.2, 55.7, 54.7, 55.0, 52.8 ,md 50.2% in 1,000 ${\mu}g/ml$ concentration, respectively. The extract of Angelicae Radix and Astragali Radix compositions with 100:0, 10:1, 5:1, 3:1, 1:1, 1:3, 1:5, 1:10 and 0:100 ratio scavenged DPPH radical with the $IC_{50}$ being 85,21, 1016.26, 656.51, 785.67 and 956.74 ${\mu}g/ml$ respectively. Conclusion : In conclusion, the extract of Angelicae Radix and Astragali Radix compositions with 1:1 ratio showed dose-dependent DPPH radical scavenging activity.

  • PDF

Effects of Chronic Disease Management Based on Clinics for Blood Pressure or Glycemic Control in Patients with Hypertension or Type 2 Diabetes Mellitus (고혈압·당뇨병 환자의 혈압·혈당 조절에 미치는 의원 기반 만성질환관리사업의 효과)

  • Cheong, Won;Yim, Jun;Oh, Dae-Kyu;Im, Jeong-Soo;Ko, Kwang Pil;Kim, Yun Mi
    • Journal of agricultural medicine and community health
    • /
    • v.38 no.2
    • /
    • pp.108-115
    • /
    • 2013
  • Objective: This study aimed to examine the effects of chronic disease management program based on clinics for blood pressure control or glycemic control in patients with hypertension or type 2 diabetes mellitus in Incheon. Methods: An observational follow up study was done on 11,501 patients registrated at clinics from January 1st to December 31st, 2010 in Incheon. Experience of education and mandatory laboratory tests were assessed with the registration data and income status was identified by National Health Insurance data. The odds ratio and 95% confidence intervals were derived from logistic regression models. Results: The experience of education has a positive effect for blood pressure control in the non-control group with hypertension at the time of registration (Odds ratio 1.357, confidence intervals: 1.112~1.655). The experience of mandatory laboratory tests has a positive effect for blood pressure control in the control group with hypertension at the time of registration (Odds ratio 1.738, confidence intervals: 1.387~2.178). But the effects of the experience of education and mandatory laboratory test in patients with type 2 diabetes mellitus were not identified. Conclusions: This study revealed the relationship between the experience of education or mandatory laboratory testing and blood pressure control in patients with hypertension.

INHIBITION OF ARTIFICIAL PLAQUE BY MUTANASE PRODUCED FROM Streptomyces exfoliatus (Streptomyces exfoliatus가 생성하는 mutanase에 의한 인공치태 억제 작용)

  • Song, Do-Won;Yang, Kyu-Ho;Chung, Jin;Oh, Jong-Suk
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.24 no.2
    • /
    • pp.449-459
    • /
    • 1997
  • The main component of dental plaque is the mutan containing the a-1,3 bond. The following results were obtained by using a blue mutan to assess the factors affecting the mutan-digesting activity of Streptomyces exfoliatus isolated from soil. A clear zone was produced by mutanase-producing Streptomyces exfoliatus on the minimal essential agar containing blue mutan. Streptomyces exfoliatus digested more blue mutan in the minimal essential broth at pH 7.0 than at pH 5.5 or 8.5. Streptomyces exfoliatus digested more blue mutan at $37^{\circ}C$ than at $32^{\circ}C$ or $42^{\circ}C$ (P<0.05). When the concentration of $CaCl_2$ was increased in the minimal essential broth, the digestion of blue mutan was increased (P<0.05). The optimal concentration of KCl was 10mM to digest blue mutan, but a similar amount of blue mutan was digested at the range of 0.1mM to 6.4mM of $MgCl_2$. When the culture supernatant of Streptomyces exfoliatus was mixed with 2X brain heart infusion broth containing 0.5% yeast extract and 10% sucrose, less artificial plaque was formed by Streptococcus mutans on the orthodontic wire (P<0.05). These results indicated that the secretion of mutanase was identified in culture supernatant of mutan-digesting Streptomyces exfoliatus, suppressing the formation of artificial plaque by Streptococcus mutans.

  • PDF

Thermoelectric Properties of ZnkIn2O3+k(k=1∼9) Homologous Oxides (Homologous 산화물 ZnkIn2O3+k(k=1∼9)의 열전 특성)

  • Nam, Yun-Sun;Choi, Joung-Kyu;Hong, Jeong-Oh;Lee, Young-Ho;Lee, Myung-Hyun;Seo, Won-Seon
    • Korean Journal of Materials Research
    • /
    • v.13 no.8
    • /
    • pp.543-549
    • /
    • 2003
  • In order to investigate the thermoelectric properties of $Zn_{k}$ $In_2$$O_{ 3+k}$ homologous compounds, the samples of $Zn_{k}$ /$In_2$$O_{3+k}$ / (k = integer between 1 and 9) were prepared by calcining the mixed powders of ZnO and $In_2$$O_3$fellowed by sintering at 1823 K for 2 hours in air, and their electrical conductivities and Seebeck coefficients were measured as a function of temperature in the range of 500 K to 1150 K. X-ray diffraction analysis of the sintered samples clarified that single-phase specimens were obtained for $Zn_{k} /$In_2$$O_{3+k}$ with k = 3, 4, 5, 7, 8, 9. Electrical conductivity of the $Zn_{k}$ $In_2$$O_{3+k}$ / decreased with increasing temperature, and decreased with increasing k for k $\geq$ 3. The Seebeck coefficient was negative at all the temperatures for all compositions, confirming that $Zn_{k}$ $In_2$$O_{3+k}$ / is an n-type semiconductor. Absolute values of the Seebeck coefficient increased linearly with increasing temperature and increased with increasing k for k $\geq$ 3. The temperature dependence of the Seebeck coefficient indicated that Z $n_{k}$I $n_2$ $O_{3+k}$ could be treated as an extrinsic degenerate semiconductor. Figure-of-merits of Z $n_{k}$I $n_2$ $O_{3+k}$ were evaluated from the measured electrical conductivity and Seebeck coefficient, and the reported thermal conductivity. Z $n_{7}$ I $n_2$ $O_{10}$ has the largest figure-of-merit over all the temperatures, and its highest value was $1.5{\times}$10$^{-4}$ $K^{-1}$ at 1145 K.5 K.

Bioethanol production from wood biomass hydrolysate with supercritical water treatment (초임계수 처리로 가수분해된 목질계 바이오매스를 이용한 바이오 에탄올 생산)

  • Seo, Hyeon-Beom;Han, Jae-Gun;Choi, Won-Seok;Lee, Oh-Kyu;Lee, Soo-Min;Choi, Seok-Hwan;Lee, Hyeon-Yong;Jung, Kyung-Hwan
    • KSBB Journal
    • /
    • v.23 no.6
    • /
    • pp.494-498
    • /
    • 2008
  • We investigated the bioethanol production using wood biomass hydrolysate which obtained from the supercritical water (SCW) treatment. SCW-treated hydrolysate was used C-source of culture medium in shaking flask culture for bioethanol production. When the concentrated SCW-treated hydrolysate (SCW3) was used, yeast cell growth was slower compared with those in other SCW-treated hydrolysate (SCW1, SCW2). In addition, the bioethanol productions were 0.51 to 0.56 (%,w/v) when SCW1, SCW2, and SCW3 were used. Therefore, we removed the toxic phenolic compound in SCW-treated hydrolysate by pretreatments of activated charcoal and calcium hydroxide. Activated charcoal reduced more efficiently the phenolic compounds in SCW3 by 94.6%. Finally, when we pretreated SCW3 by activated charcoal and this was used for bioethanol production, 0.96 (%,w/v) bioethanol was produced and the ethanol yield based on reducing sugar reached 0.5.

Destruction of Spent Organic ion Exchange Resins by Ag(II)-Mediated Electrochemical Oxidation (Ag(II)매개산화에 의한 폐 유기이온교환수지의 분해)

  • Choi Wang-Kyu;Nam Hyeog;Park Sang-Yoon;Lee Kune-Woo;Oh Won-Zin
    • Journal of the Korean Electrochemical Society
    • /
    • v.2 no.4
    • /
    • pp.183-189
    • /
    • 1999
  • A study on the destruction of organic cation and anion exchange resins by electro-generated Ag(II) as a mediator was carried out to develop the ambient-temperature aqueous process, known as Ag(II)-mediated electro-chemical oxidation (MEO) process, for the treatment of a large quantity of spent organic ion exchange resins as the low and Intermediated-level radioactive wastes arising from the operation, maintenance and repairs of nuclear facilities. The effects of controllable process parameters such as applied current density, temperature, and nitric acid concentration on the MEO of organic ion exchange resins were investigated. The cation exchange resin was completely decomposed to $CO_2$. The current efficiency increased with a decrease in applied current density while nitric acid concentration and temperature on the MEO of cation exchange resin did not affect the MEO. On the other hand, anion exchange resins were decomposed to CO and $CO_2$. The ultimate conversion to CO was about $10\%$ regardless of temperature. The destruction efficiencies to $CO_2$ were dependent upon temperature and the effective destruction of anion exchange resin could be obtained above $60^{\circ}C$.

Correlation Analysis between Head Rice Ratio and Agronomic Traits in RILs for Developing A Promising Rice Culitivar Adaptable to The Early-Transplanting Cultivation (조기재배 적합 벼품종 육성을 위한 재조합집단에서 완전미율과 농업형질과의 상관분석)

  • Lee, Jong-Hee;Choi, Jun-Hyun;Kim, Sang-Yeol;Lee, Ji-Yoon;Kim, Choon-Song;Yeo, Un-Sang;Song, You-Chen;Sohn, Young-Bo;Oh, Myung-Kyu;Kang, Hang-Won;Nam, Min-Hee
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.57 no.1
    • /
    • pp.1-6
    • /
    • 2012
  • In this study, we conducted to identify predictive parameters affecting the head rice ratio for developing high quality rice cultivar adaptable to the early-transplanting cultivation. The recombinant inbred lines (RILs) population from a cross between the parents of Pungmi and Koshihikari was used for test materials. Variations were observed in most of the measurements, eg culm length (ranging from 51.0 cm to 97.0 cm), amylose content (14.0~20.1%), protein content (5.2~7.4%), pasting properties (peak viscosity, 227.2~309.8 RVU) and head rice ratio (67.7~96.7%). Significant correlations between head rice ratio versus culm length (0.443) and head rice ratio versus protein content (-0.458) were detected in RIL population. However, culm length was negatively related to lodging tolerance. In order to develop a commercially suitable cultivar, selection for short culm and high head rice ratio of rice grains with physiochemical properties such as protein content, amylase content and taste value should be considered. This results can be used to increase the efficiency of breeding program for developing a new early-maturing rice variety adaptable to early transplanting cultivation in Korea.

Designing A V2V based Traffic Surveillance System and Its Functional Requirements (V2V기반 교통정보수집체계 설계 및 요구사항분석)

  • Hong, Seung-Pyo;Oh, Cheol;Kim, Won-Kyu;Kim, Hyun-Mi;Kim, Tae-Hyung
    • Journal of Korean Society of Transportation
    • /
    • v.26 no.4
    • /
    • pp.251-264
    • /
    • 2008
  • One of the crucial elements to fully facilitate the various benefits of intelligent transportation systems (ITS) is to obtain more reliable traffic monitoring in real time. To date, point and section-based traffic measurements have been available through existing surveillance technologies, such as loops and automatic vehicle identification (AVI) systems. However, seamless and more reliable traffic data are required for more effective traffic information provision and operations. Technology advancements including vehicle tracking and wireless communication enable the acceleration of the availability of individual vehicle travel information. This study presents a UBIquitous PRObe vehicle Surveillance System (UBIPROSS) using vehicle-to-vehicle (V2V) wireless communications. Seamless vehicle travel information, including origin-destination information, speed, travel times, and other data, can be obtained by the proposed UBIPROSS. A set of parameters associated with functional requirements of the UBIPROSS, which include the market penetration rate (MPR) of equipped vehicles, V2V communication range, and travel time update interval, are investigated by a Monte Carlo simulation- (MCS) based evaluation framework. In addition, this paper describes prototypical implementation. Field test results and identified technical issues are also discussed. It is expected that the proposed system would be an invaluable precursor to develop a next-generation traffic surveillance system.

Zoonotic Intestinal Trematodes in Stray Cats (Felis catus) from Riverside Areas of the Republic of Korea

  • Shin, Sung-Shik;Oh, Dae-Sung;Ahn, Kyu-Sung;Cho, Shin-Hyeong;Lee, Won-Ja;Na, Byoung-Kuk;Sohn, Woon-Mok
    • Parasites, Hosts and Diseases
    • /
    • v.53 no.2
    • /
    • pp.209-213
    • /
    • 2015
  • The present study was performed to survey the infection status of zoonotic intestinal trematode (ZIT) in stray cats from 5 major riverside areas in the Republic of Korea. Total 400 stray cats were captured with live-traps in riverside areas of Seomjingang ('gang' means river) (203 cats) from June to October 2010, and of Yeongsangang (41), Nakdonggang (57), Geumgang (38), and Hangang (61 cats) from June to October 2011, respectively. Small intestines resected from cats were opened with a pair of scissors in a beaker with 0.85% saline and examined with naked eyes and under a stereomicroscope. More than 16 ZIT species were detected in 188 (92.6%) cats from Seomjingang areas, and the number of worms recovered was 111 per cat infected. In cats from riverside areas of Yeongsangang, Nakdonggang, Geumgang, and Hangang, more than 9, 8, 3, and 5 ZIT species were recovered, and the worm burdens were 13, 42, 11, and 56 specimens per infected cat, respectively. As the members of family Heterophyidae, more than 10 species, i.e., Metagonimus spp., Pygidiopsis summa, Heterophyes nocens, Stellantchasmus falcatus, Heterophyopsis continua, Acanthotrema felis, Centrocestus armatus, Procerovum varium, Cryptocotyle concava, and Stictodora lari, were recovered. More than 5 species of echinostomes, i.e., Echinostoma hortense, Echinochasmus japonicus, Echinochasmus sp., Echinoparyphium sp., and unidentified larval echinostomes, were collected. Plagiorchis spp. were detected in cats from areas of Seomjingang and Yeongsangang. From the above results, it has been confirmed that stray cats in 5 major riverside areas of Korea are highly infected with various species of ZITs.

Developmental Roles of D-bifunctional Protein-A Zebrafish Model of Peroxisome Dysfunction

  • Kim, Yong-Il;Bhandari, Sushil;Lee, Joon No;Yoo, Kyeong-Won;Kim, Se-Jin;Oh, Gi-Su;Kim, Hyung-Jin;Cho, Meyoung;Kwak, Jong-Young;So, Hong-Seob;Park, Raekil;Choe, Seong-Kyu
    • Molecules and Cells
    • /
    • v.37 no.1
    • /
    • pp.74-80
    • /
    • 2014
  • The peroxisome is an intracellular organelle that responds dynamically to environmental changes. Various model organisms have been used to study the roles of peroxisomal proteins in maintaining cellular homeostasis. By taking advantage of the zebrafish model whose early stage of embryogenesis is dependent on yolk components, we examined the developmental roles of the D-bifunctional protein (Dbp), an essential enzyme in the peroxisomal ${\beta}$-oxidation. The knockdown of dbp in zebrafish phenocopied clinical manifestations of its deficiency in human, including defective craniofacial morphogenesis, growth retardation, and abnormal neuronal development. Overexpression of murine Dbp rescued the morphological phenotypes induced by dbp knockdown, indicative of conserved roles of Dbp during zebrafish and mammalian development. Knockdown of dbp impaired normal development of blood, blood vessels, and most strikingly, endoderm-derived organs including the liver and pancreas - a phenotype not reported elsewhere in connection with peroxisome dysfunction. Taken together, our results demonstrate for the first time that zebrafish might be a useful model animal to study the role of peroxisomes during vertebrate development.