• Molecules and Cells
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• v.20 no.3
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• pp.354-360
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• 2005

Neuronal damage subsequent to transient cerebral ischemia is a multifactorial process involving several overlapping mechanisms. Gangliosides, sialic acid-conjugated glycosphingolipids, reduce the severity of acute brain damage in vitro. However their in vivo effects on the cerebral cortex damaged by ischemic infarct are unknown. To assess the possible protective role of gangliosides we examined their expression in the cerebral cortex damaged by ischemic infarct in the rat. Ischemia was induced by middle cerebral artery (MCA) occlusion, and the resulting damage was observed by staining with 2, 3, 5-triphenylterazolium chloride (TTC). High-performance thin-layer chromatography (HPTLC) showed that gangliosides GM3 and GM1 increased in the damaged cerebral cortex, and immunofluorescence microscopy also revealed a significant change in expression of GM1. In addition, in situ hybridization demonstrated an increase in the mRNA for ganglioside GM3 synthase. These results suggest that gangliosides GM1 and GM3 may be synthesized in vivo to protect the cerebral cortex from ischemic damage.

• The Journal of Internal Korean Medicine
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• v.22 no.2
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• pp.127-134
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• 2001

The purpose of this investigation is to evaluate the effects of Samwha-tang(三化湯) Extracts on reversible forebrain ischemia experimentally induced from the occlusion of middle cerebral artery. The volume of cerebral ischemia, the volume of cerebral edema, and the change of pyramidal neuron of the CA1 area in hippocampus through light microscopy were investigated. we obtained the following results. The volume of the control group, which had ischemic damage was 21%, and the volume of the sample group, which had ischemic damage, was 16%. The ratio of the volume of the right/left hemisphere was 117.2 in the control group, and 108.8 in the sample group. Also, the light microscopy revealed that the pyramidal cells of CA1 area in hippocampus had many damages like changes into discontinuous and unsystematic forms. But, in the sample group, the cells were less damaged compared with the control group.

• Journal of Information Processing Systems
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• v.14 no.6
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• pp.1494-1507
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• 2018

Intelligent human identification using face information has been the research hotspot ranging from Internet of Things (IoT) application, intelligent self-service bank, intelligent surveillance to public safety and intelligent access control. Since 2D face images are usually captured from a long distance in an unconstrained environment, to fully exploit this advantage and make human recognition appropriate for wider intelligent applications with higher security and convenience, the key difficulties here include gray scale change caused by illumination variance, occlusion caused by glasses, hair or scarf, self-occlusion and deformation caused by pose or expression variation. To conquer these, many solutions have been proposed. However, most of them only improve recognition performance under one influence factor, which still cannot meet the real face recognition scenario. In this paper we propose a multi-scale parallel convolutional neural network architecture to extract deep robust facial features with high discriminative ability. Abundant experiments are conducted on CMU-PIE, extended FERET and AR database. And the experiment results show that the proposed algorithm exhibits excellent discriminative ability compared with other existing algorithms.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.34 no.5
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• pp.537-542
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• 2008

BSSRO is most frequently operated among orthognathic surgery techniques for repairment of maxillofacial deformities. In case of patients with maxillofacial asymmetry accompanying mandibular protrusion who are operated by BSSRO, this study considers the recovering time for masticatory force of each tooth and Masseteric EMG and the adequate time enabling normal occlusion. The patients who are operated with BSSRO under general anesthesia in Dankook Dental Hospital, Department of OMS are selected for this study. The control group is devided into 2. 26 patients with facial asymmetry accompanying mandibular protrusion are selected for group 1 and their maximum voluntary bite force and masseteric EMG are measured. Group 2 is formed by volunteers with healthy dentition who are measured maximum bite force and masseteric EMG on both sides of the mouth. At the week of 3rd, 5th, 7th, 9th and 11th, Mann-Whitney U test is carried on for statistical analysis and the result is as follows. 1. Patients with mandibular protrusion showed apparently low maximum bite force and masseteric EMG than patients with normal occlusion. 2. In comparison with control group 1, Occlusal force is regained in incisors and canines at the 9th week and in premolars and molars, 11th week and masseteric EMG is regained at 11th week. 3. Comparing to normal occlusal patients, no recovery could be found in experimental group in every parts of the mouth.

• Archives of Plastic Surgery
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• v.40 no.5
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• pp.505-509
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• 2013

Background The aim of this study was to collect important data on the time of oxygen saturation change in relation to skin flap color alteration using non-invasive pulse oximetry to evaluate its ability to provide continuous monitoring of skin flap perfusion. Methods An experimental study on the monitoring of blood perfusion of 20 tube-island groin flaps of 10 male New Zealand rabbits was performed using pulse oximetry. The animals were randomly assigned to one of two groups representing a blockage of either arterial or venous blood flow. The oxygen saturation change and clinical color alteration were monitored from the beginning of vessel clamping until the saturation became undetectable. The result was analyzed by the t-test using SSPS ver. 10.0. Results The mean times from the vessel clamping until the saturation became undetectable were $20.19{\pm}2.13$ seconds and $74.91{\pm}10.57$ seconds for the artery and vein clamping groups, respectively. The mean time of the clinical alteration from the beginning of vein clamping was $34.5{\pm}11.72$ minutes, while the alteration in flaps with artery clamping could not be detected until 2.5 hours after clamping. Conclusions The use of neonate-type reusable flex sensor-pulse oximetry is objective and effective in early detection of arterial and vein blockage. It provides real-time data on vessel occlusion, which in turn will allow for early salvaging. The detection periods of both arterial occlusion and venous congestion are much earlier than the color alteration one may encounter clinically.

• The Journal of Korean Academy of Prosthodontics
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• v.60 no.2
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• pp.195-201
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• 2022

Hemimandibulectomy and free fibular flap (FFF) in patients with squamous cell carcinoma could disturb the functional movement of the mandible. The muscular function in the sectioned side was compromised because of the incompetency of the muscle attachment to the mandible, leading to the unstable occlusal contact in the centric and eccentric occlusion. In this report, we present a case of a 63-year-old male who underwent cancer surgery and reconstruction with fibular graft, and he needed a fixed dental prosthesis to restore tooth loss in the anterior region. Occlusal contact change and instability were found according to the bite force in the centric relation and eccentric movement. This case report aimed to present the prosthetic procedure for fabricating the functionally optimized fixed prosthesis wherein the functionally generated path (FGP) technique and digital imaging method were applied to replicate mandibular movement and vertical dimension of the patient.

• Journal of Korean Neurosurgical Society
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• v.39 no.1
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• pp.36-39
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• 2006

Objective : The present study attempts to address the change of management results over time during the past 13 years in good-grade patients with intracranial aneurysm. Methods : Six hundred twenty five [Hunt-Hess grade I to III] out of 826 patients with ruptured intracranial aneurysms operated by the same operator within 3 days after the attack from 1990 to 2002 were selected. Since 1998, endovascular aneurysmal occlusion was done in selected cases of 21 patients. The change of management results over time, including rebleeding rate, delayed ischemic neurologic deficit[DIND] as a cause of morbidity and mortality and surgical outcome were examined. Results : The ratio of poor-grade patients in all patients tended to decrease over the years. The early rebleeding rate declined from 5.0% to 1.2% with the use of tranexamic acid and computed tomography angiogram DIND as a cause of mortality and morbidity has decreased from 12.5% in 1990 to approximately 0% currently. Surgical outcome began to improve significantly in 1994 [poor outcome : 25% in 1990, 12.2% in 1994,6.8% in 2002]. Conclusion : These results suggest that the advances in care and increased experience of the operator significantly affect the change of overall outcome, and early detection of the aneurysm is needed for reducing the ratio of poor-grade patients.

• The Journal of the Korean dental association
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• v.21 no.12 s.175
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• pp.1005-1010
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• 1983

To study the eruption process of the permanent tooth, esp., 1st molar, the author took 303 cases of oblique cephalogram (Male. 162 cases, Female: 141 cases) from age 3 to 8 yea old children, and observed the vertical change and axial change. The result were as follow: 1. The mesial end of upper 1st molar was closer to the occlusal plane than the distal, and they were erupting toward the occlusal plane by aging. In the case of lower 1st molar, the distal end was closer to the occlusal plane than the mesial and the occlusion showed the tendency to accord with the plane to be settled by aging. 2. Eruption rate of the upper and lower 1st permanent molar increased rapidly at 5 or 6 years of age. 3. Axial inclination of lower 1st permanent molar to the mandibular plane decreased gradually from 3 years of age, except for 6 years of age. There was some increase at 5 or 6 years of age.

• Proceedings of the IEEK Conference
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• 2005.11a
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• pp.363-366
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• 2005

In this paper, for detecting human faces under variations of lighting condition and facial expression, distance ranking feature and detection algorithm based on the feature are proposed. Distance ranking is the intensity ranking of a distance transformed image. Based on statistically consistent edge information, distance ranking is robust to lighting condition change. The proposed detection algorithm is a matching algorithm based on FFT and a solution of discretization problem in the sliding window methods. In experiments, face detection results in the situation of varying lighting condition, complex background, facial expression change and partial occlusion of face are shown

• Journal of the korean academy of Pediatric Dentistry
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• v.10 no.1
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• pp.7-12
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• 1983

The author used cephalometric roentgenogram to observe the longitudinal change by orthodontic treatment for early class III malocclusion in primary and mixed dentition. First, the cephalometric roentgenograms were measured and following results were obtained 1. SNA, SNB, ANB, Gonial angle, and SN to mandibular plane were measured as skeletal pattern and $\underline{1}$ to SN. $\overline{1}$ to mandibular plane and interincisal angle were measured as denture pattern. 2. Angular measurements for the Class III malocclusion were compared with those for the normal occlusion of the same Hellman dental age.