• Korean Journal of Biological Psychiatry
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• v.6 no.2
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• pp.240-245
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• 1999

Object : This study was designed to evaluate the effects of olanzapine on the schedule-induced polydipsia(SIP) which is one of animal model of obsessive-compulsive disorder in rats. We administered olanzapine as a serotonin and dopamine blocking agent, fluoxetine as a selective serotonin reuptake inhibitor, and haloperidol for the dopamine antagonist to rats which showed schedule-induced polydipsic behavior. Methods : Spraque-Dawley rats weighing 200-250gm were individually housed and maintained and allowed free access to water. The rats were placed on a restricted diet. To induce polydipsia, rats were placed in the cage where a pellet dispenser automatically dispensed 90mg pellets on a fixed-time 60 seconds(FT-60s) feeding schedule over 150 minute test session per day. Water was available at all times in the cage. After 4 weeks of daily exposure to the FT 60s feeding schedule, experimental rats met a predetermined criterion for polydipsic behavior(greater than 3 times of water per session on average). 5 groups of rats were administered olanzapine(3mg/kg, i.p), olanzapine(10mg/kg, i.p), fluoxetine(5mg/kg, i.p.), haloperidol(0.1mg/kg, i.p.), and vehicle(1cc/kg, i.p.) for 3 weeks. The rats were tested once a week to access schedule induced polydipsic behavior. Water bottles were weighed before and after the 150-minute test session. The chronic effects of administration of experimental drugs on schedule induced polydipsic behavior were analyzed with ANOVA and Scheffe test as a posthoc comparison. In order to measure water consumption in non-polydipsic food-deprived rats, a separate group of rats(N=8) were individually housed and given a single bolus(14.5gm) of food per day which maintained them at their average body weight. Results and Conclusion : The results were as follows ; 1) After 4 weeks of scheduled feeding procedure, the experimental group showed significant differences than the bolus control in the amount of water consumption as compared with their average water intakes for 4 weeks. At the same periods, there were no differences between the experimental group and the bolus control in the body weight. 2) The fluoxetine group showed significant decrease in the amount of water intake over the 3 weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 3mg group showed significant decrease in the amount of water intake at 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 10mg group showed significant decrease in the amount of water intake at 2nd and 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. However, the haloperidol group and the vehicle control group showed no changes of amounts of water intake for 3 weeks of treatment as compared with their average amount of polydipsic water intakes. 3) The fluoxetine group showed significantly lower amounts of water intake than the haloperidol group at 2nd weeks of drug treatment. And also the fluoxetine group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. The olanzapine 3mg group and the olanzapine 10mg group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. Above findings suggest that the fixed time feeding procedure for schedule-induced polydipsia as an animal model of obsessive compulsive disorder was effective to the evaluation of pharmacological challenge study. The authors assume that the serotonin hypothesis and the serotonin-dopamine interaction hypothesis are preferred to the dopamine hypothesis in the biological etiology of obsessive-compulsive disorder.

• Korean Journal of Child Studies
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• v.15 no.1
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• pp.91-108
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• 1994

This study investigated the relation between verbal abuse by parents and children's maladjusted emotional behavior. The sampling consisted of 628 children in 16 classes out of every three elementary schools and one middle school. Instruments used for this study were the Verbal Abuse Measure, Parent-to-child violence items of the Conflict Tactics Scales, Emotional Maladjustment Behavior Scale, and Socioeconmic Status. Methods applied to data analysis were multiple regression, logistic regression and logistic curve graphic display. The major findings were ; (1) Of all subjects, almost 20% experienced at least one instance in which they were victims of verbal abuse during the year covered by this study. (2) As the amount of physical abuse by parents increased the verbal abuse by parents increased. The older children experienced more verbal abuse than the younger ones. (3) Verbal abuse by parents was more highly related to maladjusted emotional behavior of the children than physical abuse by parents. (4) Regardless of the physical violence by parents, verbal abuse by parents was associated with maladjusted emotional behavior of children. Children who were subjected to both verbal and physical abuse were more strongly related to withdrawal, hyperactivity, and obsessive-compulsions than children experienced either one or the other.

• Journal of Korean Public Health Nursing
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• v.17 no.2
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• pp.299-316
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• 2003

A phenomenological methodology was used to identify the life of children living with alcoholic parents. Nine adolescents participated in the in-depth interviews, done between October and December 2001. The Colaizzi's method was used for data analysis. The results of this study are as follows. One theme and thirteen meanings were identified, The one theme is Paradoxical Coping in Life. The meanings are obsessive behavior as a way to control father's behavior, always on the defensive due to anxiety and tension, being afraid of life alone due to paranoid thoughts, contradictory expectations about father's drinking behavior due to life with chronic tension, stress becoming familiar and life being boring and tendious without stimulation, life that is fake and filled with misinterpretations about reality, affection sought from others due to loneliness, compensatory life within peer group, negative expectation about the future due to negative experiences, controling others to protect ego, denial of real emotion to protect self from hurt, life of regretting self, and strong need for approval from others. The results of this study can provide a foundation for the development of programs for children of alcohol dependent parents.

• Journal of Korea Multimedia Society
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• v.24 no.4
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• pp.583-592
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• 2021

Obsessive-compulsive disorder (OCD) is a mental disorder in which a person repeated a particular thought or feels. The domain of beliefs and guilt predicted OCD symptoms. Although there were some neuroimaging studies investigating OCD symptoms, resting-state functional magnetic resonance imaging (rs-fMRI) study investigating intra-network functional connectivity associated with guilt for OCD is not reported yet. Therefore, in the current study, we assessed the differences between intra-network functional connectivity of healthy control group and OCD group using independent component analysis (ICA) method. In addition, we also aimed to investigate the correlation between changed functional connectivity and guilt score in OCD. Total 86 participants, which consisted of 42 healthy control volunteers and 44 OCD patients, acquired rs-fMRI data using the 3T MRI. After preprocessing the fMRI data, a functional connectivity was used for group independent component analysis. The results showed that OCD patients had higher score in emotion state in beliefs and lower functional connectivity in fronto-parietal network (FPN) than control group. A decrease of functional connectivity in FPN was negatively correlated with feelings of guilt in OCD. Our results suggest excessive increase in guilt negatively affect to process emotional state and behavior or cognitive processing by influencing intrinsic brain activity.

• Child Health Nursing Research
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• v.18 no.2
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• pp.76-84
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• 2012

Purpose: This study was done to develop a cell phone addiction scale for Korean children. Methods: The process included construction of a conceptual framework, generation of initial items, verification of content validity, selection of secondary items, preliminary study, and extraction of final items. The participants were 268 children from grades 4 to 6 in two urban elementary schools. Construct validity, internal consistence reliability, and split-half reliability were used to analyze the data. Results: Nine items were categorized into 2 factors explaining 61.29% of total variance. The factors were labeled as obsessive compulsion (6 items) and dependency (3 items). Cronbach's alpha coefficient for the 9 items was .87, and Spearman-Brown coefficient was .83. Scale scores identified children as high risk users, at risk users, or average users by standard scores. Conclusion: The above findings indicate that the cell phone addiction scale for children has good validity and reliability when used with Korean children.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.30 no.2
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• pp.50-56
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• 2019

Most patients with Tourette's disorder experience an uncomfortable sensory phenomenon called the premonitory urge immediately before experiencing tics. It has been suggested that premonitory urges are associated with comorbidities such as obsessive compulsive disorder, anxiety disorders, and attention-deficit/hyperactivity disorder, although these associations have been inconsistent. Most patients experience tics as a result of the premonitory urges, and after the tics occur, most patients report that the premonitory urges are temporarily relieved. As a consequence, several studies have assessed the premonitory urge and its potential therapeutic utility. Based on the concept that the premonitory urge induces tics, behavioral treatments such as Exposure and Response Prevention and Habit Reversal Therapy have been developed. However, it is still unclear whether habituation, the main mechanism of these therapies, is directly related to their effectiveness. Moreover, the observed effects of pharmacological treatments on premonitory urges have been inconsistent.

• Journal of mucopolysaccharidosis and rare diseases
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• v.5 no.1
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• pp.29-33
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• 2021

Prader-Willi Syndrome (PWS) is a neurodevelopmental genomic imprinting disorder involving a lack of gene expression from the paternal chromosome 15q11-q13 region. This is typically due to paternal 15q11-q13 deletions (in approximately 60% of cases), maternal uniparental disomy 15, or when both 15s are from the mother (about 35% of cases). An imprinting center controls the expression of imprinted genes in the chromosome 15q11-q13 region. PWS is a neurodevelopmental disorder characterized by mental retardation and distinct physical, behavioral, and psychiatric features. Characteristic behavioral disturbances in PWS include excessive interest in food, skin picking, difficulty with a change in routine, temper tantrums, obsessive and compulsive behaviors, and mood fluctuations. Individuals with PWS typically have intellectual disabilities (borderline to mild/moderate mental retardation) and exhibit a higher overall level of behavior disturbances compared to individuals with similar intellectual disabilities. This condition severely limits social adaptations and quality of life. Different factors have been linked to the intensity and form of these behavioral disturbances, but there is no consensus regarding the cause. Consequently, there is still controversy surrounding management strategies and there is a need for new data. PWS is a multisystem disorder. Family members, caregivers, physicians, dieticians, and speech-language pathologists all play an important role in the management and treatment of symptoms in an individual with PWS. Here we analyze behavioral problems in children and adults with PWS by age and review appropriate management and treatment strategies for these symptoms.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.2 no.1
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• pp.125-134
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• 1991

In an attempt to study sex differences in child behavior disorders, 834 clinic-refered children(582 boys and 252 girls) between the ages of 6 to 11 were assessed using CBCL parental form and the data were factor analysed to form empirically derived syndromes for each sex. The analyses yielded eight behavior disorder syndromes for boys and ten, for girls. Six syndromes(aggressive, hyperactive, delinquent, social withdrawal, emotional lability, physical complaints) were found in both sexes while obsessive, depressive and psychotic syndromes were organized differently in boys and girls. There were also considerable differences in item composition of the six syndromes common to box sexes, suggesting that clinical features of common behavior disorders such as aggression and hyperactiveity might be different for boys and girls despite their apparent similarity. The results were discussed in terms of culturally shared attitudes and beliefs concerning sex differences in behaviors.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.9 no.8
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• pp.199-208
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• 2019

The escape theory is the theory of problem behavior such as suicide. The purpose of this study is to investigate the causes of gaming disorder, which has been attracting attention as a typical youth problem, through escape theory. Suicide theory is a process in which the problem triggered by the negative external environment flows into internal attribution and self-criticism, and this leads to a process leading to problematic behavior with disgust self-awareness. This process was applied to the environment, psychology, and behavior of adolescents. As a result, the lack of affection and consistency of the parents resulted in negative external environment, which affected the self-esteem of children by creating a negative external environment. And low self-esteem caused negative emotions, lowered self control, and confirmed to induce game addiction. The results of this analysis show that game addiction has a structure similar to obsessive behaviors such as binge eating and shopping addiction explained through the escape theory model and it is necessary to concentrate more on the environmental psychological factors for game addiction research.

• Journal of the Korean Applied Science and Technology
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• v.40 no.4
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• pp.897-905
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• 2023

This study attempted to reveal the influence of amateur golfers' passionate behavior on training satisfaction and training performance. Accordingly, according to the sample plan from April 1 to June 23, 2023, the key words were set for the first expert interview, "golf player," "golf training," and "golf match" to extract factors that meet the study, and are as follows through SPSS & AMOS 21.0. First, it was discovered that amateur golfers' harmony and obsessive passion had an impact (+) on training satisfaction, and second, passionate behavior had an impact on training performance. Third, it was found that training satisfaction affects training performance. Therefore, rather than distinguishing between success and failure in the process of converting to professional golf, the growth process and positive emotions should be equipped, and the expression of internalization in which self-determination is significant? Efficiency in training? The results are expected to vary depending on how it is handled.