• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제17권1호
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• pp.10-18
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• 2006

연구목적 : 본 연구는 청소년들의 인터넷 중독과 우울, 충동성, 강박성과의 연관성을 알아보고자 하였다. 연구방법 :경기도 남양주시 소재의 인문계 고등학교 1, 2학년 학생 1410명(남자 611, 여자 799)을 대상으로 하였다. 인터넷 사용 형태에 관한 설문과 인터넷 중독여부는 Young의 인터넷 중독척도(Internet Addiction Scale, IAS)를 사용하였고, 우울증상의 평가는 Beck 우울 척도(Beck Depression Inventory, BDI)를 사용하였다. 충동성 측정을 위하여 Barratt의 충동성 척도(Barratt Impulsiveness Scale, BIS)를 사용하였으며, 강박성은 모즐리 강박 척도(Maudsley obsessive compulsive inventory, MOCI)를 사용하여 평가하였다. 본 연구에서 인터넷 중독 척도 상위 25%를 중독군으로 하위 25%를 비중독군으로 분류하였다. 결 과 : 1) 남학생이 여학생보다 인터넷 중독 점수에서 유의미하게 높았고, 중독군에 포함되는 비율도 더 높았다. 2) 중독군이 비중독군보다 하루 평균 인터넷 사용시간이 유의미하게 많았고, 사용분야에서는 게임에 몰두하는 경향이 있었다. 두 군 간의 인터넷 사용기간의 차이는 없었다. 3) 인터넷 중독군이 비중독군에 비해 우울정도, 충동성, 강박성 점수가 유의미하게 더 높게 나타났다. 4) 인터넷 중독 점수는 우울정도, 충동성, 강박성 점수들과 각각 의미 있는 상관관계를 보였다. 결 론 : 우울정도, 충동성, 강박성 모두 인터넷 중독을 설명하는 변인이었으며, 그 중 충동성의 직접효과가 인터넷 중독을 가장 잘 설명하는 변인이었다. 청소년에서 높은 충동성이 인터넷 중독의 위험 인자가 될 수 있음을 시사한다. 침전물이 전반적으로 관찰되었다. Tensile strength는 NaOCl군에서 다른 군에 비해 유의성 있는 증가를 보였으며 (p < 0.05). elongation rate는 3 종의 소독제 모두 대조군에 비해 유의성 있는 증가를 보였으나 (p < 0.05), 특히 ChloraPrep군에서 가장 큰 증가를 보였다. 본 연구 결과 3 종의 소독제 모두 근관충전 전 가타파차 콘의 rapid sterilization을 위해 유용하게 사용할 수 있음을 시사한다.

• 생물정신의학
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• 제4권2호
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• pp.179-187
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• 1997

The clinical efficacy of serotonin reuptake inhibitors such as clomipramine in the treatment of obsessive compulsive disorder(OCD) has fueled interest in the neurobiological basis of this illness. OCD is responsive exclucively to potent serotonin reuptake inhibitors clomipramine, fluoxetine, fluvoxamine, sertraline, and paroxetine and this point forms the important evidence supporting a cental role for serotonin in the pathogenesis of the disorder. Other serotonergic medications such as lithium, buspirone, trazodone, or fenfluramine may be useful as adjuvant treatments in treatmentrefractory OCD and adjuvant antipsychotics are useful in tic disorders, personality disorders, and psychotic disorders. This paper reviews results of treatment studies, investigations of biological markers, and neuroendocrine challenges and implications for the role of serotonin in pathophysiology and treatment of OCD.

• 대한불안의학회지
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• 제3권1호
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• pp.20-25
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• 2007

The definite causes of obsessive-compulsive disorder (OCD) are still unknown. OCD has been suggested to be related to many neurotransmitters in brain, such as serotonin, dopamine and glutamate. It has been shown that serotonergic neurons play a crucial role in the pathophysiology of OCD. Recently, it is known that neurotransmitters other than serotonin also play a role in the pathophysiology of OCD, and a series of studies have provided a few evidence that glutamate may be involved in some OCD patients. The purpose of this article was to review the literatures on glutamatergic dysfunction in OCD. We suggest that glutamatergic dysfunction may be implicated in the pathophysiology of OCD.

• 보험의학회지
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• 제29권1호
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• pp.7-11
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• 2010

Anxiety disorders Anxiety disorders are among the most prevalent mental disorders in the general population. Anxiety disorders can be viewed as a family of related but distinct mental disorders, which include following as classified in the text revision of fourth edition of Diagnostic and Statistical Manual Disorders(DSM-IV-TR): (1) panic disorder with or without agoraphobia; (2) agoraphobia with or without panic disorder; (3) specific phobia; (4) social phobia; (5) obsessive-compulsive disorder; (6) posttraumatic stress disorder; (7) acute stress disorder; (8) generalized anxiety disorder. An acute intense attack of anxiety accompanied by feeling of impending doom is known as panic disorder. The term phobia refer to an excessive fear of a specific object, circumstance, or situation. Obsessivecompulsive disorder is represented by a diverse group of symptoms that include intrusive thoughts, rituals, preoccupations, and compulsions. Posttraumatic stress disorder is a condition marked by development of symptoms after exposure to traumatic life events. Generalized anxiety disorder is defined as excessive anxiety and worry about several events or activities for most days during at least a 6-month period.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제4권1호
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• pp.164-172
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• 1993

저자는 한 청소년 강박장애 환자의 정신치료에서, 무의식을 다루는 전통적 정신치료보다는 역동적 이해를 바탕으로 의식의 영역을 다루는 비특이적 정신치료와 가족치료를 병행하여 좋은 치료 결과를 경험하여 이를 보고하였고, 특히 환자 자신이 이러한 것을 치료 과정에서 스스로 찾아내었고 또 치유되었다는 것을 환자의 표현을 통해서 제시하고자 하였다. 또 이러한 복합적인 치료 과정이 의식의 영역을 다루는 것이라는 점에서 행동요법이나 인지치료 등 기존 치료 경험과 일치함을 문헌 고찰을 통해 밝히고 있다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제16권2호
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• pp.183-191
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• 2005

뚜렛 장애는 음성틱과 운동틱을 특징으로 하는 소아기의 대표적인 신경발달학적 행동장애이다. 소아기 발병 강박장애는 강박장애의 한 아형으로써 틱장애와의 연관성이 알려져 있다. 두 질환은 처음 진단시, $40\~75\%$에서 서로 공존질환으로서 발견되며, 유전학적으로도 관련성이 있으며 신경해부학적으로도 피질-선초체-시상 회로(cortico-striato-thalmic circuit)의 이상이 보고되며 증상적인 면에서도 유사점이 발견되고 있다. 최근 10여년 동안 틱장애와 소아기 발병 강박장애 영역에서는 놀라울 정도로 많은 연구들이 진행되었다. 본 연구는 뚜렛 장애를 포함하는 틱장애와, 소아 청소년 발병 강박 장애에서 1) 임상 양상 2) 유전학 및 역학 연구 3) 뇌영상 연구 4)신경화학 5) 연쇄구균 감염 관련 소아기 자가면역성 신경정신과적 질환(pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection : PANDAS)에 대해 고찰하고자 한다.

• 생물정신의학
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• 제6권2호
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• pp.253-258
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• 1999

The fluoxetine is one of the most frequently prescribed drugs for the treatment of depression and obsessive-compulsive disorder(OCD). This has been known as one of the most safest medication. But since the advent of this drug, there have been several reports of side effects-the mania and suicidal ideation-encountered during coadministration of fluoxetine with or without other psychotropic drugs. We experienced a case of 20 years old male OCD patient who developed into abrupt manic state and also was preoccupied with intense suicidal ideation following fluoxetine use. He was a only child in his family and his father had a history of alcoholism about 15years ago. Our patient's obsessive-compulsive symptoms have been occured since puberty. His OCD symptoms and anxiety were aggravated since joining the army. Beside these facts, we could not find any other psychiatric history such as depressive disoder and bipolar disorder. We used the fluoxetine starting dosage of 20mg and increased to 40mg at second week. About 3 weeks after the treatment, he developed sudden manic symptom and more aggravated suicidal ideation without any OCD symptoms. He felt vitalized and energetic without having enough sleep and food. These symptoms were ceased over two weeks by stopping medication. Up to this point, the reason why fluoxetine induces mania and suicidal preoccupation is unclear. But somehow the fluoxetine has effects on serotonin receptor and serotonin-dopamine regulations, thus we could make an assumption that fluoxetine can induce mania, extrapyramidal symptoms(EPS) and suicidal ideation in some part of the serotonin unbalanced patients. We think this would be the first report to remark on fluoxetine's suicidal and manic side effects in Korea. So here we present the case with the summary of reviewed articles.

• 생물정신의학
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• 제12권2호
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• pp.151-158
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• 2005

Background:Clozapine is a unique atypical antipsychotic medication. It is considered to be superior, even amongst the newer agents, in treatment-resistant schizophrenia. However, de novo emergence or exacerbation of obsessive-compulsive(OC) symptoms during treatment with clozapine has been reported. We prospectively evaluated 19 cases which newly developed OC symptoms during clozapine treatment and discussed the treatment of OC symptoms induced by it. Methods:We recruited 19 patients(8 males, 11 females) with a DSM-IV diagnosis of schizophrenia and schizoaffective disorder who had developed OC symptoms during clozapine treatment. OC symptoms were assessed using the Padua-ICMA and YBOCS on a monthly basis over three months. Results:Eleven female and eight male patients were enrolled and the average age of patients was 32.8 years. At baseline, no patients showed OC symptoms. Moderate to severe OC symptoms appeared with mean daily dose of 298.68 mg of clozapine. There were no significant differences in improving OC symptoms between the clozapine dose reduction group and the OC treatment group. Conclusion:We noticed the possibility that the appearance of OC symptoms is connected with the effect of clozapine. The clozapine-induced OC symptoms were improved both by reducing clozapine daily doses, and by adding OC treatment drugs. With other atypical antipsychotics now available, to know and treat the side effects of clozapine would be of considerable value, offering clinical guidance in making a decision on treatment-resistant schizophrenia.

• 한국콘텐츠학회논문지
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• 제11권6호
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• pp.155-166
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• 2011

본 연구는 예능프로그램을 시청한 후 색채프로그램을 실시한 실험집단과 실시하지 않은 통제집단의 심리상태(강박증, 불안 및 적대감)에 어떠한 영향을 미치는지 확인하기 위해 실시하였으며, 결과는 다음과 같다. 첫째, 색채프로그램에 참여한 실험집단의 심리상태(강박증, 불안 및 적대감)는 사전 검사치보다 사후 검사치 모두 95% 통계수준에서 유의적으로 낮아졌으나 통제집단을 그런 변화가 나타나지 않았다. 둘째, 예능프로그램을 시청한 후 색채프로그램을 참여한 대학생들의 색채표현에서 빨강색과 파랑색의 지각이 폭넓게 나타났다. 이러한 변화는 흰색의 이성과 검정의 억압에서 현재 해야 할 일에 대한 책임감을 갖는 변화과정이라고 해석할 수 있었다. 결론적으로, 예능프로그램을 시청한 대학생들의 심리상태에 긍정적인 영향을 줄 수 있도록 다양한 색채 프로그램을 교육과정에 도입하는 것은 의미 있다고 본다.

• 한국임상보건과학회지
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• 제2권3호
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• pp.188-194
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• 2014

Purpose. The aim of this study was to provide for guidance of life, counsel and check their mental condition and analysis of correlation between MBTI personality type and emotional experience in university students. Methods. Data was analyzed by students whom participated in the research on the diagnose of mind of students from m university men and woman who accomplished to MBTI personality survey. Results. These result emotional experience of male-female that had deserved hospitality(p=0.22) statistically. This result had deserved emotional experience of extraversion personality of MBTI personality type in hospitality(p=0.000),introvert personality type in interpersonal sensitivity(p=0.002). It had deserved thinking extraversion personality type in obsessive-compulsive(p=0.000)emotional personality type in depression(p=0.000)in hostility(p=0.000). It had deserved judgement personality type in interpersonal sensitivity(p=0.043). Conclusions. The results of this study were as follow. Frist as a result of MBTI personality type of emotional experience on extraversion it was found that hospitality was leveled high and personality type of introversion is that Interpersonal sensitivity was leveled high. Thinkful personality type was leveled high on obsessive-compulsive. As a result of this study, personality indexes of MBTI of university student, it was found that there was related to emotional experience.