• Title/Summary/Keyword: Obsessive

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Comorbid Obsessive Compulsive Disorder and Social Function in Stable Patients with Chronic Schizophrenia (안정화된 만성 정신분열병 환자에서 강박장애 동반과 사회적 기능)

  • Kang, Suk-Hoon;Seok, Jung-Ho;Kim, Chan-Hyung;Kim, Yoon-Joong;Kim, Hyoung-Ju;Choi, Jong-Hyuck
    • Anxiety and mood
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    • v.7 no.1
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    • pp.40-47
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    • 2011
  • Objective : This study aimed to investigate the prevalence of obsessive-compulsive disorder (OCD) in schizophrenia, and the relationship among OCD, severity of psychopathology, and social function in stable patients with chronic schizophrenia. Methods : We interviewed 138 symptom-stable inpatients who had been on a constant dose of antipsychotics for at least 1 month prior and diagnosed as chronic schizophrenia. Subsequently, patients were classified according to the existence of OCD as investigated using the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I) and the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). Further, all clinical and demographic data was investigated. To investigate potential interrelationships, the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Korea-Positive and Negative Symptom Scale (K-PANSS), and the Korean Personal and Social Performance (K-PSP) were used. An independent ttest and Chi-square test were used to compare groups and a Pearson's correlation coefficient was used to assess the relationship between the Y-BOCS and other clinical rating scales. Results : The prevalence of OCD in schizophrenia patients was 18.1%. Patients with schizophrenia and OCD exhibited significantly earlier onset of schizophrenia, more severe psychiatric symptoms, and lower personal and social performance ability as compared to those without OCD. There was no significant relationship among Y-BOCS, K-PANSS, and K-PSP. Conclusion : We found that comorbid OCD was relatively more frequent in patients with schizophrenia. An investigation involving larger samples of schizophrenia patients with OCD with respect to social function and thus, the effect on quality of life is required.

Association between the GRIN2B Gene and Age of Onset in Obsessive-Compulsive Disorder (글루타메이트 수용체(GRIN2B) 유전자와 강박장애 발병 연령과의 관련성)

  • Hwang, Syung-Shick;Roh, Dae-Young;Kim, Chan-Hyung
    • Anxiety and mood
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    • v.7 no.1
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    • pp.34-39
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    • 2011
  • Objectives : An early age at onset of obsessive compulsive symptoms in family studies has been strongly associated with a more familial form of obsessive compulsive disorder (OCD). Further, many reports have suggested that early- and late- onset OCD represent separate subtypes of the disorder. The aim of this study was to investigate the associations between the glutamate receptor, the ionotropic, n-methyl-d-aspartate (NMDA) subunit 2B gene (GRIN2B) polymorphisms, and onset of OCD in the Korean population. Methods : We recruited 109 OCD patients and classified them into early- (age of onset <18 years) and late-onset groups (age of onset${\geq}$18). Genomic DNA was extracted from their blood after which the genotypes and allelic frequencies of the two GRIN2B polymorphisms (5072T/G and 5988T/C) were compared in the two groups. We also compared genetic data between child- (age of onset${\leq}$15) and adult-onset groups (age of onset${\geq}$19) using the same protocol. Results : There were no significant differences between the early- and late-onset groups with respect to genotype. Moreover, we could not find any differences in genotype frequencies between child and adult-onset groups. Conclusions : Our study suggested that GRIN2B polymorphisms (5072T/G and 5988T/C) do not affect the onset of OCD in Koreans. However, this finding has resulted from a preliminary study and thus, further study is required.

Conceptual Understanding of Thought-Action Fusion and Cognitive Fusion : Focus on Obsessive-Compulsive Symptoms (사고-행동 융합과 인지적 융합의 개념적 이해 : 강박증을 중심으로)

  • Lee, Sang Won;Lee, Kyung-Uk;Choi, Mina;Lee, Seung Jae
    • Anxiety and mood
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    • v.15 no.1
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    • pp.1-12
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    • 2019
  • Thought-action fusion (TAF) is a tendency to blindly assume causal relations between their thoughts and external reality. On the other hand, cognitive fusion (CF) is a tendency to take internal experiences, such as thoughts and feeling, literally rather than view them as random events. However, these two terms are often confusedly used and, in fact, have conceptual overlaps. Therefore, this study aimed to identify their distinctive features through a comprehensive review of the definition, origin, measurements and clinical implications especially on the understanding of obsessive-compulsive symptoms. The cognitive-behavioral concept of TAF is confined to erroneous and maladaptive beliefs about the connection between thoughts and behaviors. The CF is a broader construct that entails taking thoughts and feelings as facts and engaging or struggling with them such that the quality of life is lowered. They also have different theoretical backgrounds, developing processes and therapeutic approaches. From the perspective of the obsessive-compulsive disorder, both concepts have been studied as mid-structures for this illness. Recently, the effectiveness of psychological therapies related to these concepts such as defusion therapy has been tested. However, it is yet still in its infancy. In the future, complementary advances between the two concepts with studies on biological substrates is needed.

Is Grit Different from Passion? Assessing Cross-Cultural Differences Through the Use of Multiple-Group Factor Analysis (그릿(Grit)과 열정은 변별되는가? 다집단요인분석을 이용한 비교문화 연구)

  • Kim, Jungeun;Yang, Sujin
    • Korean Journal of Culture and Social Issue
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    • v.27 no.4
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    • pp.411-434
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    • 2021
  • The purpose of this research was to examine the discrimination between grit and passion; and to compare the relationship between grit and passion between eastern and western culture. The participants were 208 Korean and 251 American undergraduates. Multiple-group factor analysis confirmed the model of four (consistency of interest, perseverance of efforts, harmonious passion, and obsessive passion) factors by configural invariance and partial measurement invariance. Also we found positive correlation between consistency of interest and harmonious passion as well as negative correlation between consistency of interest and obsessive passion in the American sample. However, the correlation between grit(consistency of interest, perseverance of efforts) and passion(harmonious passion, obsessive passion) was not significant in the Korean sample. The results suggest that grit is not accompanied by passion among Korean university students. Findings empirically highlight the distinctiveness of grit and passion and the possibility of cultural differences in grit and passion, which were usually discussed western cultures.

The Role of Intolerance of Uncertainty in Anxiety and Depressive Disorders (불안 및 우울 장애에 있어서 불확실성에 대한 불내성의 역할)

  • Lee, Jun-Yeob;Lee, Sang-Hyuk;Suh, Ho-Suk
    • Anxiety and mood
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    • v.9 no.1
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    • pp.3-9
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    • 2013
  • Intolerance of uncertainty (IU) is defined as the tendency to react negatively on an emotional, cognitive, and behavioral level to uncertain situations and events. However, this definition is somewhat categorical and does not explain the phenomenology of IU. Intolerance of uncertainty scale (IUS), the standard measure of IU, was considered to have two factors : 'unacceptability and avoidance of uncertainty' and 'uncertainty leading to the inability to act'. IU may be a cognitive vulnerability factor for clinical worry and generalized anxiety disorder (GAD). A number of moderators and mediators including cognitive avoidance, experiential avoidance and rumination influence the relationship between IU, worry, obsessive-compulsive symptoms, anxious and depressive symptoms. IU may be more strongly related to the symptoms of GAD than to symptoms of other anxiety disorders including obsessive-compulsive disorder (OCD), and major depressive disorder. IU may serve as an important transdiagnostic feature across anxiety and depressive disorders. Incorporating IU-specific treatment components into therapeutic protocols may result in pervasive benefits, and not only for those with GAD or OCD, but for people with any anxiety disorder or with depression.

A Retrospective Study on the Effect of Traditional Korean Medicine on Obsessive-Compulsive Disorder (강박장애 환자의 한방치료 효과에 대한 후향적 연구)

  • Choi, Kang-Eah;Lee, Yu-Jin;Kim, Yeonju;Yoo, Jong-Ho
    • Journal of Oriental Neuropsychiatry
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    • v.33 no.3
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    • pp.329-337
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    • 2022
  • Objectives: To examine effects of traditional Korean medical treatment on obsessive-compulsive disorder (OCD). Methods: Effects of Korean medical treatment on patients with OCD who visited the neuropsychiatric clinic of Korean medicine were examined. Patients were treated with acupuncture, herbal medication, and oriental psychotherapy. Padua-ICMA, Y-BOCS, BDI-2, STAI-X1/X2, BAI were compared before and after 8 and 12 weeks of treatment to determine whether symptoms of patients were improved. Results: After 8 weeks treatment (n=19), Padua-ICMA, Y-BOCS, BDI-2, STAI-X1/X2, and BAI scores were significantly decreased. After 12 weeks treatment (n=12), Padua-ICMA, Y-BOCS, BDI-2, STAI-X1/X2, and BAI scores were also significantly decreased. Conclusions: Traditional Korean medicine is clinically effective in treating OCD.

A STUDY ON MENTAL HEALTH STATE OF HIGH SCHOOL STUDENTS (고등학생의 정신건강 상태에 관한 연구 -SCL-90을 이용, 서울시 인문계 1 . 3학년을 중심으로-)

  • 김은주
    • Korean Journal of Health Education and Promotion
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    • v.5 no.2
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    • pp.110-141
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    • 1988
  • This study was conducted to find out the mental health state of high school students. First-year students and third-year students af liberal high schools is Seoul were subject to this study. Questionnaire of Symptom Checklist-90 and various factors was adopted for the survey. A total of 916 questionnaires was sellected for the analysis, and the results are obtained as follows; 1) The characteristics in responses to mental health scale showed that obsessive-compulsive scale score was the highest, followed by interpersonal-sensitivity, depression, hostility, and anxiety. The subject group of the students showed higher scores in nine symptom dimensions except somatization than other normal group. 2) Girl-students showed higher scores than boy-students in somatization, depression, and anxiety, whereas the opposite was true in hostility. 3) Third-year students got high scores, in somatization, anxiety and Depression. 4) Parental marriage state of the repondents showed significant differences in nine symptom dimensions of mental health. Scores of the students with parents was the lowest, followed by those of students with only mother, only father and the rest(no parents, divorced, sepaerated, step-parent) in increasing order. 5) Smoking students showed high score in obsessive-compulsive, depression, hostility, paranoid ideation, and psychoticism. Especially in hostility, they got much higher score. 6) Students with poor record at school got higher scores in every symptom dimension than those with good record at school, especially in obsessive-compulsive and depression scale. 7) Parents' attitude toward student showed significant effect on every scale. Students under over-expectation or indifference from parents were in bad mental health state. 8) Students who have advisor proved to be in better mental health state than those who never consult their personal problems with others. 9) He who has family history got higher scores in some scales. 10) Respondents who looked upon what they have learned in high school as being rather an obstacle to sound social life got high scores in all the symptom dimensions and next came those of the students who answered that there were a lot of unnecessary things in their learning. 11) Those for whom it would not quite necessary to enter college if there were little formal schooling discrimination in society got high scores in obsessive-compulsive, interpersonal sensitivity, depression, hostility, and in psychoticism, especially higher in obsessive-compulsive scale. 12) Mental health state of the students who are influenced by the social surroundings, mass media, and the home environments showed high score in 8 symptom dimensions. 13) Abnormal response frequency of this sample is as follows; 24.0% of boys, 23.8% of girls, 22.5% of the first-year students, and 26.9% of the third-year students. There were significant difference among the grades. 14) The factors of distinctive correlation between the dimensions of SCL-90 and 16 factors were the father's negative attitude and depression, negative responses on teaching contents and anxiety, and smoking and hostility. In conclusion, mental health state of liberal highschool students on the whole showed worse than other normal groups. It had close terms with relation with their parents, schoolwork, smoking, teaching contents, the social surrounding, mass media, and the home environments. Thus I believe there need not only mental health education of students, training of teachers, counceling of parents, but also changes in teaching contents, and the improvement of educational system and the social surroundings under the national support.

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Lifetime Prevalence and Comorbidity in Obsessive-Compulsive Disorder and Subclinical Obsessive-Compulsive Disorder in Korea (강박장애 및 아임상형 강박장애의 평생 유병률과 병발성)

  • Hong, Jin-Pyo;Lee, Dong-Eun;Hahm, Bong-Jin;Lee, Jun-Young;Suh, Tong-Woo;Cho, Seong-Jin;Park, Jong-Ik;Lee, Dong-Woo;Bae, Jae-Nam;Park, Su-Bin;Cho, Maeng-Je
    • Anxiety and mood
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    • v.5 no.1
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    • pp.29-35
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    • 2009
  • Background : In spite of the worldwide relevance of obsessive-compulsive disorder Ed-highlight : Unclear. Perhaps consider changing word choice. (OCD), there are considerable differences in prevalence, sex ratio, comorbidity patterns, and sociodemographic correlates. Data on subclinical OCD have been sparse to date. Methods : Data stemmed from the Korea Epidemiologic Catchment Area (KECA) study which had been carried out from April to December 2001. Korean versions of DSM-IV adapted Composite International Diagnostic Interview were administered to a representative sample of 6275 persons aged 18-64 living in the community. DSM-IV based criteria for subclinical OCD were applied. Results : The lifetime prevalence rates for OCD and subclinical OCD were 0.8% and 6.6%, respectively. In both OCD and subclinical OCD, the rates for males and females were not statistically different. OCD was demonstrated to be associated with depressive disorder, bipolar disorder, social phobia, generalized anxiety disorder, and alcohol and nicotine dependence. Additionally, subclinical OCD was associated with posttraumatic stress and somatoform disorders. Comorbidity rates in subclinical OCD were lower than those in OCD. Conclusions : The lifetime prevalence rate for OCD was less than 1% in the Korean general population. Age distribution and comorbidity patterns suggest that subclinical OCD represents a broad and heterogeneous syndrome and not simply a milder form of OCD.

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A Case Report : Hypersexuality and Obsessive-Compulsive Behaviors in a Stroke Patient with the Left Mesial Frontal Cortex and Both Basal Ganglia Lesion (좌측 정중 전두엽과 양측 기저절 경색 후 과잉성욕 증상과 강박 증상을 보인 환자 1례)

  • Kim, Se Joo;Kim, Young Shin;Choi, Nak Kyung;Lee, Byung-Chul;Lee, Man Hong
    • Korean Journal of Biological Psychiatry
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    • v.8 no.2
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    • pp.271-275
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    • 2001
  • Hyposexuality after stroke has been frequently observed, but hypersexuality as a sequela of stroke has not been commonly documented. We report a patient who exhibited hypersexuality and obsessive-compulsive behaviors after stroke in the region of the left mesial frontal cortex and both basal ganglia. At 2 months after stroke, he visited psychiatric unit due to these symptoms. His motor function was almost full recovered. He was treated with fluvoxamine and perphenazine. With two-month medication, his hypersexuality and obsessive-compulsive behavior disappeared. This case may indicate that basal ganglia-thalamocortical circuit plays an important role in the mediation of sexual behavior and obsessive-compulsive behavior. Since changes in sexual activity may not be spontaneously reported, a systemic inquiry into patient's sexual functioning after infarction in frontal lobe or basal ganglia is warranted.

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DEVELOPMENT OF KOREAN FORM OF CHILDREN'S YALE-BROWN OBSESSIVE-COMPULSIVE SCALE(CY-BOCS):A RELIABILITY AND VALIDITY STUDY (한국판 아동용 예일-브라운 강박 척도 ; 신뢰도와 타당도 연구)

  • Lee, Jeoung-Seop;Kang, Yun-Hyong;Cho, Seong-Jin;Suh, Dong-Hyuck;Hong, Kang-E;Chung, Sung-Ju
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.11 no.1
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    • pp.60-69
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    • 2000
  • Objective:This study was carried out to evaluate the reliability and validity of the Korean form of the Children's Yale-Brown Obsessive Compulsive Scale(CY-BOCS). Method:Forty-two children with obsessive-compulsive disorder(OCD)(31 boys and 11 girls, aged 7 to 18 years) were assessed with CY-BOCS. Interrater agreement was assessed by two raters in subsample(n=20). discriminant and convergent validity were assessed by comparing CY-BOCS scores to Clinical Global Impression-OCD(CGI-OCD), Leyton Obsessional Inventory-Child Version (LOI-CV), State-Trait Anxiety Inventory for Children(STAI-C), and Child Depression Inventory(CDI). Results:Internal consistency was high, measuring 0.86 for the 10 items and total score. The intraclass correlations for the CY-BOCS total, obsession, and compulsion scores were 0.94, 0.94, 0.84, suggesting excellent interrater agreement for subscale and total scores. The CY-BOCS total score showed highest correlation with CGI-OCD(r=0.88), and significant correlation with LOI-CV(r=0.51), Trait Anxiety score(r=0.43), and CDI scores(r=0.49), but it was not correlated with State-Anxiety score(r=0.25). Conclusion:The results of this study indicate that the Korean form of CY-BOCS is a reliable and valid scale for rating obsessive-compulsive symptom severity.

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