• Title/Summary/Keyword: Observation Amount

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A Study on Metabolic Effects of Norinyle Administration on Female Guinea Pig (Norinyle 복용이 체내대사에 미치는 영향에 대한 연구)

  • Kim, Chang-Yeon;Ju, Soon-Jin
    • Journal of Nutrition and Health
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    • v.12 no.4
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    • pp.29-42
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    • 1979
  • In order to observe metabolic effects of an oral conceptive, Norinyle, on female Guinea pig, the changes of ascorbic acid amount and alkaline phosphatase activity in the liver and serum were determined, and histochemical changes of the uterus were observed by microscopic and electronmicroscopic methods by administration of Norinyle with or without ascorbic acid. The results obtained are summerized as follows: 1) The metabolic changes were clearly influenced by the administration of Norinyle alone, but the changes were diminshed by administration of Norinyle with ascorbic acid. 2) The adimnistration of Norinyle influenced to increases the requirment of ascorbic acid in the liver. 3) The uterus weight of the Norinyle administered group was much increased, while the weight was less increased in the group of administered Norinyle with ascorbic acid than the control. 4) The Norinyle administration was brought about an atrophy of endometrium, of uterus especially, functional layer, that the formation of glands were inadequately and the fromation of basal layer and stroma were diminished. 5) An acute infarction on the all layers of the uterus was developed at 9th and 25th days of Norinyle administration and 20th day of Norinyle with ascorbic acid administration. 6) A hypertrophy of stromal and endovascular cells were observed on the groups administered of Norinyle alone(group II ) or Norinyle with ascorbic acid(group IV). 7) It was observed that amount of collagen fiber in the basal and muscular layeres of uterus were diminished under a microscopical observation by the special stained specimen on the Norinyle administered group, but the amount and distribution of reticulin fiber were not changed significantly. 8) The fille structure of outer functional layer of the uterus were significantly changed by administration of Norinyle which were shown irregurarity of nuclear membrane, poor development ana significant expansion of enaoplasmic reticulum, decreases of the amount of ribosome due to slip off, increases of the number of dense bodies, obvious formation of vaccule, an4 decreases the amount of collagen in inner and outer layer of the stroma. 9) The amount of ascorbic acid in the serum did not much changed but the amount in the liver was much decreased by the administration of Norinyle, And the administration of Norinyle with ascorbic acid induced for a significant diminishing on the changes of uterus which might be able to developed by the administration of Norinyle alone.

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Impact of IPCC RCP Scenarios on Streamflow and Sediment in the Hoeya River Basin (대표농도경로 (RCP) 시나리오에 따른 회야강 유역의 미래 유출 및 유사 변화 분석)

  • Hwang, Chang Su;Choi, Chul Uong;Choi, Ji Sun
    • Journal of Korean Society for Geospatial Information Science
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    • v.22 no.3
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    • pp.11-19
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    • 2014
  • This study is analyze future climate and land cover change affects behaviors for amount of streamflow and sediment discharge within basin. We used the climate forecast data in RCP 4.5 and 8.5 (2011-2100) which is opposite view for each other among RCP scenarios that are discussed for 5th report for IPCC. Land cover map built based on a social economic storyline in RCP 4.5/8.5 using Logistic Regression model. In this study we set three scenarios: one scenario for climate change only, one for land cover change only, one for Last both climate change and land cover change. It simulated amount of streamflow and sediment discharge and the result showed a very definite change in the seasonal variation both of them. For climate change, spring and winter increased the amount of streamflow while summer and fall decreased them. Sediment showed the same pattern of change steamflow. Land cover change increases the amount of streamflow while it decreases the amount of sediment discharge, which is believed to be caused by increase of impervious Surface due to urbanization. Although land cover change less affects the amount of streamflow than climate change, it may maximize problems related to the amount of streamflow caused by climate change. Therefore, it's required to address potential influence from climate change for effective water resource management and prepare suitable measurement for water resource.

An Empirical Analysis of the Relationship between Advertisement Expenses and Business Performance (광고선전비와 경영성과 간의 실증적 분석)

  • Park, Kyung-Lak
    • Korean Business Review
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    • v.11
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    • pp.277-293
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    • 1998
  • The purpose of this study is to analyse the overall relationship between the advertisement expenses and the two major indicies of business performance, that is, the total amount of sales and the discipline have contrasted the expenses for commercial advertisement with the total amount of sales or with the business performance, respectively, utilizing data on a specific product observed through 3 to 5 years. This study attempts to enlarge the scope of observation and the content of analysis. In order to attain the purpose of this study, the rate of increase in the advertisement expenses is taken as the independent variable and the two major indicies of business performance, the total amount of sales and the resultant interest, as the dependent variables. Business companies or firms which have continually been listed on the board of Korea Stock Exchange for 14 years, from 1982 to 1995, were grouped into four major business categories; 1)Food and beverage industries, 2)Fiber, clothings, and leather industries, 3) Medicine, chemistry, oil, coal, and rubber industries, and 4) Assembled mechanics and metallurgy, machinery, and maintenance industries. Utilizing the KIS-DATA, compiled by Korea Credit Evaluation, Ltd., 30 to 40 samples of business companies or firms were randomly selected from each category. Finally 125 samples were selected and put into regression analyses and follow-up tests by appropriate statistical models, in order to verify if there were any noticeable correlations. The final result obtained through the afore-mentioned research method shows that the amount of advertisement expenses has strong correlations with the amount of sales and the resultant interest. Viewed by business category, in the case of fiber, clothings, and leather industries, the relationship turned out to be significant only with the rate of increase in the total amount of sales, while, in the case of food and beverage industries, the rate of increase in the total amount of sales showed a negatively significant correlations.

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Regional Climate Simulations over East-Asia by using SNURCM and WRF Forced by HadGEM2-AO (HadGEM2-AO를 강제자료로 사용한 SNURCM과 WRF의 동아시아 지역기후 모의)

  • Choi, Suk-Jin;Lee, Dong-Kyou;Oh, Seok-Geun
    • Journal of the Korean earth science society
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    • v.32 no.7
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    • pp.750-760
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    • 2011
  • In this study, the reproducibility of the simulated current climate by using two regional climate models, such as Seoul National University Regional Climate Model (SNURCM) and Weather Resuearch and Forecasting (WRF), is evaluated in advance to produce the standard regional climate scenario of future climate. Within the evaluation framework of a COordinated Regional climate Downscaling EXperiment (CORDEX), 28-year-long (1978-2005) regional climate simulation was conducted by using the Hadley Centre Global Environmental Model (HadGEM2-AO) global simulation data of the National Institute of Meteorological Research (NIMR) as a lateral boundary forcing. The simulated annual surface temperatures were in good agreement with the observation; the spatial correlation coefficients between each model and observation were over 0.98. The cold bias, however, were shown over the northern boundary in the both simulated results. In evaluation of the simulated precipitation, the skill was reasonable and good. The spatial correlation coefficients for the precipitation over the land area were 0.85 and 0.79 in SNURCM and WRF, respectively. It is noted that two regional climate models (RCMs) have different characteristics for the distribution of precipitation over equatorial and midlatitude areas. SNURCM shows better distribution of the simulated precipitation associated with the East Asia summer monsoon in the mid-latitude areas, but WRF shows better in the equatorial areas in comparison to each other. The simulated precipitation is overestimated in summer season (JJA) rather than in spring season (MAM), whereas the spatial distribution of the precipitation in spring season corresponds to the observation better than in summer season. Also the RCMs were capable of reproducing the annual variability of the maximum amount and its timing in July, in which the skills over the inland area were in better agreement with the observation than over the maritime area. The simulated regional climates, however, have the limitation to represent the number of days for extremely hot temperature and heavy rainfall over South Korea.

Influence of Panax Ginseng upon mating Behavior of Male Rats (인삼이 흰쥐의 성 행위에 미치는 영향)

  • Kim, Chul;Choi, Hyun;Kim, Chung-Chin;Kim, Jong-Kyu;Kim, Myung-Suk;Ahn, Byung-Tae;Park, Hyoung-Jin
    • The Korean Journal of Physiology
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    • v.8 no.1
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    • pp.15-22
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    • 1974
  • The influence, upon male rat's mating behavior, of Korean Panax Ginseng administered for 3 and 5 days was investigated by direct behavioral observation and also by counting the number of copulation plugs the animals deposited. Four쇼-four male albino rats were used. Part of the animals received ginseng for 3 days (ginseng-3 day group, N= 12) or for 5 days(ginseng-5 day group, H=10), while the remaining animals received saline for 3 days (saline-3 day group, N=12) or for 5 days (saline-S day group, N=10). Each animal belonging to the 2 ginseng groups received subcutaneously 0.5 ml/100 g body weight of ginseng alcohol extract solution (4 mg of the ethyl alcohol extract in 1 ml of physiological saline), and each rat belonging to the 2 saline groups received the same amount of saline per day. During the dark period of the light-dark cycle on the next day following the last drug administration, a female rat in the artificial estrus was introduced to each male and the mating behavior was observed for 45 minutes. The observation session was divided into two parts and, in the early part which terminated with the first ejaculation and succeeding intromission, following behavioral measures were taken: mounting latency, intromission latency, inter-intromission period, ejaculatory latency(time from the first intromission until the first ejaculation), occurrence of mounting with intromission, occurrence of mounting without intromission, and postejaculatory interval. Behavioral measures taken in the later part of the session after the first ejaculation were: occurrence of mounting with intromission, occurrence of mounting without intromission, and occurrence of ejaculation. Immediately after the behavioral observation session the experiment turned to measure, for 10 days, the number of copulation plug which each pair of rats deposited. Following results were obtained: 1. After several mountings mounting with intromission, males of the 2 ginseng groups finished the first ejaculation significantly earlier than the corresponding 2 saline groups did. 2. The postejaculatory latency was significantly reduced in the ginseng-5 day group compare with the value of the saline-5 day group and also compared with the value of the ginseng-3 day group. 3. The 2 ginseng groups ejaculated significantly more often in 45 minutes' observation session than the corresponding 2 saline groups did. 4. The number of copulation plug deposited in 10 days by the animals of the 2 ginseng groups. significantly exceeded the number deposited by the corresponding 2 saline group animals. The animals of the ginseng-5 day group deposited copulation plugs significantly more than the animals of the ginseng-3 day group did. It is inferred from the above results that the ginseng facilitates mating behavior of male rats, and that the degree of facilitation may be influenced by the duration of drug administration.

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The Effect that the Application of Time-Based Electrolysis Has on Acute Ischemia

  • Lee, Jung Sook;Song, Young Wha;Kim, Sung Won
    • Journal of International Academy of Physical Therapy Research
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    • v.6 no.2
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    • pp.846-851
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    • 2015
  • This neurological damage accelerates the infection reaction of cells and apoptosis at the time of reperfusion after ischemia occurs. BCL-2/BCL-2 allogeneic begeminum has a function of suppressing the apoptosis of cells, and thus it is inferred that the susceptibility of cells to apoptosis is determined by the amount of allogeneic begeminum present which is determined based on the amount of BAX. Ischemia was induced in SD mice by occluding the common carotid artery for 5 minutes, after which blood was re-perfused. NEES was applied to acupuncture points, at 12, 24, and 48 hours post-ischemia on the joksamri, Hapgok. Protein expression was investigated through BAX antibody immuno-reactive cells in the cerebral nerve cells and Western blotting. The results were as follows: In the present study as well, as a result of observation of the change in the number of the BAX reaction cells after the inducement of GI, there was the aspect of most of the BAX reaction cells being observed in the corpus striatum area of the GI group 24 hours after the inducement of ischemia. This revealed the same results as those of previous studies in which the change in the number of BAX reaction cells occurred in all areas while ischemia was in progress. The change in the expression of BAX protein after 24 hours showed that there was a very significant reduction in the NEES group compared to the GI group (p<.01). As a result, a greatest amount of change in the number of BAX immunoreactive cells related to apoptosis 24 hours after ischemia appeared in the NEES group. This study that ischemia increases the expression of BAX that induces apoptosis. Thus, it is determined that ischemia is the main cause of the apoptosis of neurons, and this study reveals that low frequency needle electrode electrical stimulation has the effect of blocking the apoptosis of neurons by reducing protein related to the apoptosis of cells that has increased after ischemia has occurred.

A Study on the Effect of Ca and P on the Microstructure in Solidification of Al-7wt%Si-0.3wt%Mg Alloy (Al-7wt%Si-0.3wt%Mg 합금의 응고시 미세조직에 미치는 Ca 및 P의 영향에 관한 연구)

  • Kwon, Il-Soo;Kim, Jeong-Ho;Kim, Kyoung-Min;Yoon, Eui-Pak
    • Journal of Korea Foundry Society
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    • v.18 no.4
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    • pp.349-356
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    • 1998
  • In this study, the influence of impurity element Ca, P on solidification behavior and morphology of eutectic silicon was examined by observation of microstructure and by DSC analysis. In the case of 1.3 ppm P, eutectic Si was fine and fibrous when the added amount of Ca was 500 ppm, However, the modification of eutectic Si was depressed by formation of polygonal Ca-Si compounds when the addition amount of Ca was greater than 1000 ppm. The addition of Ca 500 ppm depressed the primary and eutectic temperature. The primary and eutectic temperature were depressed with Ca 500 ppm but rather ascended when the addition amount of Ca was more than 1000 ppm. When the content of P was 17.5 ppm, eutectic Si had modified morphology with Ca addition. DAS was increased, the primary temperature was ascended and eutectic temperature was depressed with Ca added. Eutectic Si appeared as coarse flake phase and DAS was decreased with the increase of P content. The existence of P in the melt depressed the primary temperature and ascended eutectic temperature.

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Microstructure of Non-Sintered Inorganic Binder using Phosphogypsum and Waste Lime as Activator

  • Kim, Ji-Hoon;An, Yang-Jin;Mun, Kyung-Ju;Hyung, Won-Gil
    • Journal of the Korea Institute of Building Construction
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    • v.18 no.3
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    • pp.305-312
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    • 2018
  • This study is about the development of a non-sintered binder (NSB) which does not require a sintering process by using the industrial by-products Phosphogypsum (PG), Waste Lime (WL) and Granulated Blast Furnace Slag (GBFS). In this report, through SEM analysis of the NSB paste hardening body, micropore analysis of paste using the mercury press-in method and microstructure observation were executed to consider the influence of the formation of the pore structure and the distribution of pore volume on strength, and the following conclusions were reached. 1) Pore structure of NSB paste of early age is influenced by hydrate generation amount by GBFS and activator. 2) Through observing the internal microstructure of NSB binder paste, it was found that the strength expression at early age due to hydration reaction was achieved with a large amount of ettringite serving as the frame with C-S-H gel generated at the same time. It was confirmed that C-S-H gel wrapped around ettringite, and as time passed, the amount generated continually increased, and C-S-H gel tightly filled the pores of hardened paste, forming a dense network-type web structure. 3) For NSB-type cement, the degree of formation of gel pores below $10{\mu}m$ had a greater influence on strength improvement than simple pore reduction by charging capillary pores, and the pore size that had the greatest effect on strength was micropores with diameter below $10{\mu}m$.

An Optimization of distributed Hydrologic Model using Multi-Objective Optimization Method (다중최적화기법을 이용한 분포형 수문모형의 최적화)

  • Kim, Jungho;Kim, Taegyun
    • Journal of Wetlands Research
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    • v.21 no.1
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    • pp.1-8
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    • 2019
  • In this study, the multi-objective optimization method is attemped to optimize the hydrological model to estimate the runoff through two hydrological processes. HL-RDHM, a distributed hydrological model that can simultaneously estimate the amount of snowfall and runoff, was used as the distributed hydrological model. The Durango River basin in Colorado, USA, was selected as the watershed. MOSCEM was used as a multi-objective optimization method and parameter calibration and hydrologic model optimization were tried by selecting 5 parameters related to snow melting and 13 parameters related to runoff. Data from 2004 to 2005 were used to optimize the model and verified using data from 2001 to 2004. By optimizing both the amount of snow and the amount of runoff, the RMSE error can be reduced from 7% to 40% of the simulation value based on the initial solution at three SNOTEL points based on the RMSE. The USGS observation point of the outflow is improved about 40%.

Quality Characteristics of Sulgidduk Added with Fresh Sweet Potato (생고구마를 첨가한 설기떡의 품질특성)

  • Oh, Hyun-Eui;Hong, Jin-Sook
    • Korean journal of food and cookery science
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    • v.24 no.4
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    • pp.501-510
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    • 2008
  • In this study, we evaluated the quality characteristics of sweet potato Sulgidduk produced with varying amounts of fresh sweet potato, after three days of storage. The more fresh sweet potato was added, the higher were the levels of crude protein and crude lipid; however, crude ash contents were lowest in the control sample, and no significant differences in this value were detected among the samples to which fresh sweet potatoes were added. Moisture contents evidenced a tendency to decrease with increases in the amount of added fresh sweet potato and increased storage time, but pH rose with increases in the amount of added sweet potato. Total cell counts showed a tendency toward decrease with increases in the amount of added fresh sweet potato. L values tended to be low with increases in the amount of added fresh sweet potato and a values were lowest immediately after its production, although no consistent tendencies were noted in correlation with the amount of added fresh sweet potato. b values tended to increase directly with the amount of added sweet potato . With increasing storage time, the L and a values decreased, whereas the b value tended to increase. Upon textural assessment, it was observed that hardness, adhesiveness, springiness, gumminess, and chewiness(all textural components except for cohesiveness) increased with increasing quantities of added fresh sweet potato, and these factors also tended to increase with the progression of storage time. After observation via scanning electron microscopy(SEM), it was noted that the cohesiveness also increased with increasing amounts of added sweet potato. With regard to the sensory evaluation, the samples to which 15% fresh sweet potato had been added evidenced the highest acceptability in terms of color, flavor, and s0weetness, and softness and moistness in these samples decreased with increasing percentages of added sweet potato. It has been previously demonstrated that the addition of 15% fresh sweet potato resulted in optimal overall acceptability. In accordance with the aforementioned results, it has been verified that the use of fresh sweet potato in Sulgidduk is possible and probably desirable, and an addition of 15% sweet potato appears to be the optimal approach in terms of overall quality and functionality.