• 한국자동차공학회논문집
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• 제23권2호
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• pp.185-190
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• 2015

The purpose of this study is developing the quantify the seat belt pulling Noise index and evaluation method. This paper presents the objective method to evaluate the emotional feeling about the pulling Noise of the seat belt. The physical quantification is required to objectively evaluate the emotional feeling of the pulling Noise. This is called the "Noise metric." The Noise metric is should correlated to the subjective rating of the pulling Noise. The pulling Noise index is developed throughout the linear regression of the Noise metric and the subjective rating. The developed index is used for the objective evaluation of the emotional feeling about the pulling Noise of a seat belt throughout the modification of seat belt components.

• 대한핵의학회지
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• 제38권3호
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• pp.241-252
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• 2004

목적: 다수의 뇌 자료를 기반으로 구성된 통계적 화률뇌지도는 복잡하고 개인적인 편차가 큰 뇌의 형태학적, 기능적 특성을 분석하는데 유용하다. 특히 최근에 한국인의 정상 MR 영상을 기반으로 한 구조적 기능적 뇌 표준판과 구조적 확률뇌지도가 완성되었으며. 부검뇌의 조직절편을 활용한 세포구축학적 확률뇌지도가 도입되었다. 이 연구에서는 이들 자료를 활용하여 뇌 영상의 국소계수를 객관적으로 측정하기 위한 정량화 기법을 개발하였으며, 이를 이용하여 정상 한국인의 뇌 영상자료를 분석하였다. 대상 및 방법 : T1 MRI와 FDG PET에 대한 뇌 표준판을 성별, 연령별로 개발하였으며, 한국인 정상 MR 영상으로 만들어진 89개 뇌 영역의 구조적 확률뇌지도와 독일 율리히 연구센터에서 도입한 13개 브로드만 영역에 대한 세포구축학적 확률뇌지도를 뇌 표준판 위로 각각 비선형 변환하였다. 확률뇌지도에 정의된 각 뇌 영상의 국소계수는 확률에 의한 가중평균 또는 가중합으로 구하였다. 확률뇌지도를 이용한 예비 연구로 정상 노화에 따른 포도당대사의 변화가 대상회 내에서 전 후 위치에 따라 다르게 나타나는 가를 조사하였다. 결과: SPM과의 연계된 사용을 고려하여 Matlab 상에서 작성된 정량화 프로그램은 20초 미만에 1개의 공간정규화된 영상을 처리할 수 있었다. 대상회 포도당 대사에 대한 분석에서 후대상회에 대한 문측-전대상회 및 미측-전대상회의 계수 비는 정상 노화에 따라 매우 유의하게 감소하였다. 즉. 문측-전대상회/후대상회는 매 10년마다 3.1%씩 감소하였으며($P<10^{-11}$, r=0.81) 미측-전대상회/후대상회는 1.7%씩 감소하였다($P<10^{-8}$, r=0.72). 문측-전대상회와 미측-전대상회의 계수비 감소 역시 유의하였다(P<0.0005. r=0.52, 1.5%/year). 결론: 서양인 뇌에 기반한 확률뇌지도는 그동안 제한적으로만 사용되어 왔으나 한국인 뇌 표준판과 확률뇌지도 및 이 연구에서 개발한 정량화 기법은 일반에 공개하기로 하여 더욱 널리 쓰이게 되면 국내 뇌 연구 활성화에 기여할 것으로 기대 된다.

• Journal of Pharmaceutical Investigation
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• 제33권1호
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• pp.37-43
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• 2003

The objective of this study is to prepare ketoprofen (KP) - poly(ethylene glycol) (PEG) conjugates and to investigate their degradation kinetics. KP-PEG conjugates were synthesized from KP and PEG methy1ester by esterification in the presence of DCC. The KP-PEG conjugates (KPEG) were characterized by IR and $^{1}H-NMR$ spectroscopy. The hydrolysis of KPEG with time was studied using HPLC by simultaneous quantification of KP and KPEG. The hydrolysis rate constant was high at low and high pHs, and showed minimum at pH 4 and 5. As the size of KPEG increases, hydrolysis rate increased. The slope of degradation rate profile suggests that catalytic reaction seems to occur by specific acid/base catalysis. These results suggest that KPEG could be used as a prodrug for KP, which releases KP slowly in the body.

• 오토저널
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• 제11권5호
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• pp.76-89
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• 1989

With the objective of studying the response of brain tissue in a transient rotational acceleration of the head, as occurs in car crash, the problem of a cylindrical case containing a prototype brain material of silicone gel and subjected to a rotational acceleration around the axis of the cylinder is analysed. The prototype material is considered to be homogeneous and isotropic, and is modeled alternatively as a linear elastic or a linear viscoelastic solid. The computational model for the present problem consists of a 3-dimensional isoparametric finite element model, wherein large deformations and large strains are treated through the updated Lagrangian approach. A comparison of the results of the present 3-dimensional computations, with the attendant assumptions on material data, is made with the results of independent experimental study. The deformation profiles and the major characteristics of response of the brain material are in good agreement with the test results. Moreover, the study suggests the possibility that the use of more accurate material data may yield very useful results even appropriate for accurate quantification of deformations.

• 한국경영과학회지
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• 제16권2호
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• pp.79-79
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• 1991

This paper presents an automated visual inspection/measuring system for the door inner panel manufacturing process. The main objective of this research is to develop inspection applications with a machine vision system related to the determination or quantification of parameters such as dimension, shape, quality of surfaces, number of holes in a panel, and presence or absence of specific features. For quality measurements, we showed a subpixel image processing technology that will improve the consistency of results and level of precision. Also presented is a data analysis method th detect process shifts so that corrective action can be undertaken before more defective units are manufactured.

• 대한인간공학회지
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• 제17권1호
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• pp.11-22
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• 1998

When grasping a movable object or making an object move, humans feel kinesthetic sense. The kinesthetic sense is the human sense that the human feels in response to the motion acted on him. The objective of the paper is to transform the kinesthetic sense associated with the human arm into the quantified data that are useful from the engineering viewpoint. A 2-dimensional motion generator composed of two linear motors was developed to provide various motion patterns. It can change its stiffness and damping values on the real-time basis by properly regulating the force generated by the linear motors. Based on Taguchi method, the most dominant factors to affect the kinesthetic sense were investigated. Also, a reference function adequate to quantify the kinesthetic sense was found. Based on this function, the effects of changes in stiffness and damping on the kinesthetic sense were investigated. Various tests show that the damping is a more dominant factor than the stiffness in forming the kinesthetic sense.

• 경영과학
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• 제16권2호
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• pp.79-92
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• 1999

This paper presents an automated visual inspection/measuring system for the door inner panel manufacturing process. The main objective of this research is to develop inspection applications with a machine vision system related to the determination or quantification of parameters such as dimension, shape, quality of surfaces, number of holes in a panel, and presence or absence of specific features. For quality measurements, we showed a subpixel image processing technology that will improve the consistency of results and level of precision. Also presented is a data analysis method th detect process shifts so that corrective action can be undertaken before more defective units are manufactured.

• 대한핵의학회지
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• 제39권2호
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• pp.124-132
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• 2005

Cardiac PET emerged as a powerful tool that allowed in vivo quantification of physiologic processes including myocardial perfusion and metabolism, as well as neuronal and receptor function for more than 25 years. Wow PET imaging has been playing an important role in the clinical evaluation of patients with known or suspected ischemic heart disease. This important clinical role is expected to grow with the availability of PET/CT scanner that allow a true integration of structure and function. The objective of this review is to provide an update on the current and future role of PET in clinical cardiology with a special eye on the great opportunities now offered by PET/CT.

• 농촌계획
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• 제3권2호
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• pp.102-111
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• 1997

For rational agricultural land use planning, it is quite necessary to get hold of land suitability precisely and to make decision on land use patterns accordingly. In the methodological viewpoint, objective and scientific evaluation techniques for land suitability classification should be supported for the systematic land use planning. As one of technical development approaches to rational land use planning, this study tried to frame a land suitability evaluation system for agricultural purposes. Evaluation unit is defined as a tract of land bounded by road, other land units and topographical features. And quantification theory was applied in the determination works of evaluation criteria. The administrative area of Namsa-myon(district), Yongin-si(city), Kyunggi-do(province) was selected for the case study. In order to check the feasibility of the evaluation system developed in the study, field check team, consisting of 2 government officers and 2 representative farmers, carried out evaluation works by observation on 148 sample land units, 10% of total 1,480 ones. Between estimated and observed results, there showed very good relationship of its multiple correlation coefficient, R=0.9467.

• 한국자동차공학회논문집
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• 제8권5호
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• pp.138-147
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• 2000

Vehicle suspension systems are parts which effect performances of a vehicle such as ride quality, handing characteristics, straight performance and steering effort etc. Kinematic design is a decision of joints` position for straight performance and steering effort. But, when vehicle is rebounding and bumping, chang of joints` displacement is nonlinear and a surmise of straight performance and steering effort at that joints` position is difficult. So design of suspension systems is done through a inefficient method of tried-and-error depending on designer`s experience. In this paper, kinematic design of suspension systems was done through the optimal design using a genetic algorithm. For this optimal design, the function for quantification of straight performance and steering effort was made, and the kinematic design method of suspension systems having this function as the objective function was suggested.