• Journal of the Korean Institute of Gas
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• v.20 no.2
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• pp.49-57
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• 2016

Aqueous ammonia is widely used in household cleaners, fertilizers and denitrification process. It is usually treated in concentrations from 10 % to 30 %, and release accidents have occurred frequently. In this study, we developed a simplified estimating method and equation to calculate threat zone easily in case of emergency due to release accident of aqueous ammonia. We calculated the consequence distance for toxic endpoints of aqueous ammonia(concentration 10 % ~ 30 %) at different puddle areas($1m^2{\sim}500m^2$) using the ALOHA program. Based on the result, we analyzed the relationship between concentration and puddle area with the threat zone and created the equation.

• Lettere Italiane
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• no.37
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• pp.177-209
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• 2012

La Sicilia è una terra, difficile da governare perché è difficile da capire nella natura dei suoi abitanti, contraditoria ed estrema. In questa ricerca si cerca di comprendere la Sicilia, i suoi problemi e i problemii meridionali attraverso maggiormente 『Sicila come metafora』 di Leonardo Sciascia. La Sicilia, come sfondo, ci viene presentata nell' opera sciasciana, in un palcosenico sul quale le virtù del popolo siciliano si pervertono e tutte le loro qualità divengono radice di opposti effetti. Prima di iniziare di capirne va cercato la sua storia: senza considerare la storia non si puo e non si deve riflettere le situazioni attuali nè i problemi. Si può affermare che l'insicurezza è la componente primaria della storia siciliana, la quale regola e condiziona il proprio modo di essere, la visione di vita e dell'ambiente. È interessante studiare la propria storia di Sicilia e si fa cominciare a capirne gradualmente: uno degli elementi della realtà siciliana che ricorre spesso è la mafia, e anche il costume, le donne. Sciascia citta nel 『Il cavaliere e la morte』 che la sicurezza del potere si fonda sull'insicurezza dei cittadini. È talmente assurdo da capire ma questa è la Sicilia. Raggiungendo una definizione della natura dei siciliani con i testi di Sciascia, si potrebbe reppresentare la sicilianità o sicilitudine. Sapendo cos'è e come è la sicilianità capire la Sicilia significa per un siciliano capire se stesso. E poi si puo riflettere meglio dei problemi storici e attuali dell'Italia del Sud, di mafia, dei costumi e delle vittime in quella societa cio'è delle donne. Così il termine sicilianità caratterizza quell'insieme dei caratteri attribuiti all'uomo di Sicilia, tipici cioè del siciliano, definiti anche sicilitudine. E nel scritto Sciascia affermò che la Sicilia è in una situazione molto complicata e disperata. Ora si potrebbe capirlo anche chi sta fuori di quel luogo cosi si potrebbe cercare anche di rimettere in ordine delle cose e di risolverne finalmente.

• Journal of the Korean Institute of Gas
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• v.22 no.3
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• pp.38-44
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• 2018

Ammonia is used primarily as a refrigerant in refrigeration facility and SCR of a plant, and is frequently involved in leakage accidents. This study was conducted by selecting ammonia, a material with a wide influence range when evaluated, as a material with higher vapor pressure and lighter than air. In this study, the influence ranges were computed using KORA(Korea Off-site Risk Assessment supporting tool) with four different environmental factors : ground roughness, sealing, operating temperature, pressure, and leakage hole size. As a result, the difference in the influence range of ground roughness is approximately 4.62 times, while the ammonia storage tank shows a difference in the reduction rate of 0.64 when sealed. The extent of impact increased with increasing leakage depending on storage temperature and pressure, and when storing higher than the saturation vapor pressure, the impact range showed an average growth rate of 3.45 % per 0.1 Mpa($45^{\circ}C$). The influence ranges based on the size of the leakage holes is shown to be proportional to the area of the leakage zone.

• Journal of the Korean Home Economics Association
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• v.11 no.3
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• pp.329-344
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• 1973

The purpose of this study is to find how the mother's rearing patterns and attitudes influence on a child's social personality development. Many contemporary psychologists insist that mother's rearing attitudes and methods before age of six influence on child's social personality development a great deal. Freud divided the child's developmental stages into three : oral, anal, and phallic period. According to his assumptions the way of mother's feeding and weaning has very important relationship with the personality development through ora period and how to handle toilet training will greatly influence through anal period. In addition to this, Symonds declares that a mother's rearing attitudes will influence the establishment of social characteristics of the child. The moderate attitude-not too overprotective or rejective or submissive or dominate-is desirable. If mother's attitude declines to one aspect among these four kinds too much, the child would have chances to develop maladjusted social characteristics such as aggressiveness , submissiveness, dependency, and dominativeness. The hypotheses of this study were based on Freud and Symonds theory and tested by correlation and the difference of percentage. The results of the study were as follows : I. The relationship between rearing pattern and social characteristics 1. When the child has too strictly scheduled feeding time, he will have aggressive attitudes. 2. The longer the feeding period, the more dependency the child will have. 3. In case the toilet training was taken place too early or strictly, the child will withdraw into his shell. 4. When the child failed to perform the toilet training and was punished because of that, the child's personality will likely to be too submissive or aggressive. II. The relationship between mother's attitudes and social personality 1. When the mother's attitude is too overprotective the child showed withdrawn characteristics (r = 89) or dependency ( r = 24). 2. The child whose mother has too rejective attitude also showed withdrawn characteristics ( r = 31). As Sears insisted self-demanding schedule is recommendable and the weaning supposed to be started after age of one and a half years and finished around age of two. The toilet training which has rather severe consequences than the feeding methods should be started when the child is able to understand what is expected to him. Sears says that about two years after birth would be proper but individual difference should be considered. As a conclusion, Flexible and understanding attitudes and rearing methods is necessary for a sound establishment of social personality.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.4
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• pp.355-360
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• 2010

Purpose: Analysis performance for spectacle lens which sales in domestic market and optimization design a spectacle lens which is corrected aberration. Methods: Measured center thickness, radius and aspherical surface coefficient for spherical and aspherical lenses which were ${\pm}$5.00D. Refractive index for every lens was 1.6 and they came from 4 different companies. I used 3 types of equipment to measure lenses. ID-F150 (Mitutoyo) : Center Thickness, FOCOVISION (SR-2, Automation Robotics) : Radius, PGI 1240S (Taylor Hobson) : Aspherical surface coefficient. Designed a lens which had 27 mm of distance from lens rear surface to center of eye, 4 mm of pupil diameter and small aberration on center vision $30^{\circ}C$. To shorten axial distance compared with the measured lens rise merits for cosmetic. Lens Design tool was CODE V (Optical Research Associates). Results: -5.00D aspherical lens had somewhat high astigmatism and distortion compared with the spherical lens. But it had a merit for cosmetic because of short axial height and decrease edge thickness. Improved a performance of distortion and ascertain merits for cosmetic due to short axial height and decrease edge thickness same as (-) lens in case of +5.00 aspherical lens. Though an optimization process front surface aspherical lens had a good performance for astigmatism and distortion and the merit for beauty compared with measured spherical lens. Conclusions: Design trend for domestic aspherical lens is decrease axial height and thickness to increase a merit for cosmetic not but increase performance of aberration. From design theory for optimization design front surface aspherical spectacle lens which has improved performance of aberration and merit for cosmetic at the same time compared with the measured lens. Expect an improved performance from design back aspherical lens compared with front aspherical lens.

• Journal of Ecology and Environment
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• v.32 no.4
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• pp.237-247
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• 2009

This study was conducted to determine the carbon (C) contents in different mixed stands of P. dens if/ora and deciduous oak species in Gwangneung, central Korea. Five mixed stands with different ratios of P. densiflora and deciduous oak species were chosen based on the basal area of all trees ${\geq}\;5cm$ DBH: pure P. densiflora (P100D0), 70% P. densiflora + 30% deciduous oak species (P70D30), 44% P. densiflora + 56% deciduous oak species (P50D50), 37% P. densiflora + 63% deciduous oak species (P40D60), and 10% P. densiflora + 90% deciduous oak species (P10D90). Total C contents in the overstory (aboveground and belowground) vegetation were higher in the mixed stands (P70D30, P50D50, P40D60) than in the pure stands (P100D0, P10D90). Moreover, except for P40D60, C contents of forest floor (litter and coarse woody debris) were larger in the mixed stands (P70D30, P50D50) than in the pure stands. However, total soil C contents up to 30cm depth were highest in the pure deciduous oak stand than in the pure P. densiflora stand and mixed stands. Total ecosystem C contents (Mg/ha) were 163.3 for P100D0, 152.3 for P70D30, 188.8 for P50D50, 160.2 for P40D60, and 150.4 for P10D90, respectively. These differences in total ecosystem C contents among the different mixed stands for P. densiflora and deciduous oak species within the study stands were attributed by the differences in vegetation development and forest management practices. Among the five study stands, the total ecosystem C contents were maximized in the 1:1 mixed ratio of P. densiflora and deciduous oak species (P50D50).

• BMB Reports
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• v.46 no.11
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• pp.561-566
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• 2013

We examined the ways in which fenobam could promote not only the transduction of PEP-1-FK506BP into cells and tissues but also the neuroprotective effect of PEP-1-FK506BP against ischemic damage. Fenobam strongly enhanced the protective effect of PEP-1-FK506BP against $H_2O_2$-induced toxicity and DNA fragmentation in C6 cells. In addition, combinational treatment of fenobam with PEP-1-FK506BP significantly inhibited the activation of Akt and MAPK induced by $H_2O_2$, compared to treatment with PEP-1-FK506BP alone. Interestingly, our results showed that fenobam significantly increased the transduction of PEP-1-FK506BP into both C6 cells and the hippocampus of gerbil brains. Subsequently, a transient ischemic gerbil model study demonstrated that fenobam pretreatment led to the increased neuroprotection of PEP-1-FK506BP in the CA1 region of the hippocampus. Therefore, these results suggest that fenobam can be a useful agent to enhance the transduction of therapeutic PEP-1-fusion proteins into cells and tissues, thereby promoting their neuroprotective effects.

• BMB Reports
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• v.48 no.11
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• pp.618-623
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• 2015

FK506 binding protein 12 (FK506BP) is a small peptide with a single FK506BP domain that is involved in suppression of immune response and reactive oxygen species. FK506BP has emerged as a potential drug target for several inflammatory diseases. Here, we examined the protective effects of directly applied cell permeable FK506BP (PEP-1-FK506BP) on corneal alkali burn injury (CAI). In the cornea, there was a significant decrease in the number of cells expressing pro-inflammation, apoptotic, and angiogenic factors such as TNF-α, COX-2, and VEGF. Both corneal opacity and corneal neovascularization (CNV) were significantly decreased in the PEP-1-FK506BP treated group. Our results showed that PEP-1-FK506BP can significantly inhibit alkali burn-induced corneal inflammation in rats, possibly by accelerating corneal wound healing and by reducing the production of angiogenic factors and inflammatory cytokines. These results suggest that PEP-1-FK506BP may be a potential therapeutic agent for CAI.

• BMB Reports
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• v.49 no.7
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• pp.382-387
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• 2016

Reactive oxygen species generated under oxidative stress are involved in neuronal diseases, including ischemia. Glutathione S-transferase pi (GSTpi) is a member of the GST family and is known to play important roles in cell survival. We investigated the effect of GSTpi against oxidative stress-induced hippocampal HT-22 cell death, and its effects in an animal model of ischemic injury, using a cell-permeable PEP-1-GSTpi protein. PEP-1-GSTpi was transduced into HT-22 cells and significantly protected against H2O2-treated cell death by reducing the intracellular toxicity and regulating the signal pathways, including MAPK, Akt, Bax, and Bcl-2. PEP-1-GSTpi transduced into the hippocampus in animal brains, and markedly protected against neuronal cell death in an ischemic injury animal model. These results indicate that PEP-1-GSTpi acts as a regulator or an antioxidant to protect against oxidative stress-induced cell death. Our study suggests that PEP-1-GSTpi may have potential as a therapeutic agent for the treatment of ischemia and a variety of oxidative stress-related neuronal diseases.

• BMB Reports
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• v.50 no.9
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• pp.460-465
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• 2017

Polycystic kidney disease (PKD) is one of the most common inherited disorders, involving progressive cyst formation in the kidney that leads to renal failure. FK506 binding protein 12 (FK506BP) is an immunophilin protein that performs multiple functions, including regulation of cell signaling pathways and survival. In this study, we determined the roles of PEP-1-FK506BP on cell proliferation and cyst formation in PKD cells. Purified PEP-1-FK506BP transduced into PKD cells markedly inhibited cell proliferation. Also, PEP-1-FK506BP drastically inhibited the expression levels of p-Akt, p-p70S6K, p-mTOR, and p-ERK in PKD cells. In a 3D-culture system, PEP-1-FK506BP significantly reduced cyst formation. Furthermore, the combined effects of rapamycin and PEP-1-FK506BP on cyst formation were markedly higher than the effects of individual treatments. These results suggest that PEP-1-FK506BP delayed cyst formation and could be a new therapeutic strategy for renal cyst formation in PKD.