• Microbiology and Biotechnology Letters
• /
• v.34 no.1
• /
• pp.35-39
• /
• 2006

One of the fermentative metabolism of enteric Escherichia coli was imitated after rumen bacteria, which have high C4 metabolism. E. coli expresses phosphenolpyruvate carboxylase (PPC) for the pathway between phosphoenolpyruvate (PEP) and oxaloacetate (OAA) during glycolytic condition while expresses phosphoenolpyruvate carboxykinase (PCK) during gluconeogenic condition. In contrast to enteric E. coli, rumen bacteria express the PEP-OAA pathway only by PCK. To verify the effect of the regulation imitation on the C4 metabolism of E. coli, PPC-deficient E. coli strain with PCK expression in glycolytic condition was constructed. The PEP-OAA regulation modified E. coli strain increased 2.5-folds higher C4 metabolite than the wild type strain. The potential use of C4 metabolism by regulation control is discussed.

• Journal of the Korea Institute of Military Science and Technology
• /
• v.20 no.3
• /
• pp.337-344
• /
• 2017

In this paper, the optical axis alignment(OAA) of an infrared sensor(IRS) using a microwave sensor(MWS) was presented as a method of an axis alignment to minimize the problems that could be caused by the misalignment of the two sensors in the missile including the dual-mode sensor. The azimuth(AZ) and elevation(EL) angles of the two targets used for each sensor test were calculated by using the transformation equation and the test results of the MWS and IRS, and then the proposed OAA was verified by comparing the angles. Furthermore, the validity of the proposed OAA was demonstrated by confirming the abnormality of the OAA through the test results of the electro optical head(EOH) of the IRS which was equipped with a tilt on the missile fuselage.

• Korean Journal of Medicinal Crop Science
• /
• v.19 no.6
• /
• pp.491-500
• /
• 2011

Ursolic acid, triterpenoid compound has been shown to stimulate osteoblast differentiation and enhance bone formation. In the present study, we examined the effects of similar triterpenoid compounds, oleanolic acid (OA) and its derivatives, such as oleanolic acid acetate (OAA) and oleanolic acetate methyl ester (OAM) on the bone formation in MC3T3-E1 osteoblast cells. We determined cellular proliferation, alkaline phosphatase (ALP) activity, mineralization, and expression of osteoblast specific genes and mitogen activated protein kinase phosphorylation. Treatment of $0.1-10{\mu}m$ OA, OAA, and OAM increased cellular proliferation, but not significantly increased as compared with dimethyl sulfoxide (DMSO). OA, OAA, and OAM at 5uM concentration enhanced ALP expression, mineralization, and osteocalcin (OCN) mRNA level. In conclusion, OA and its derivatives stimulated the osteoblast differentiation by increasing ALP, mineralization, and OCN mRNA expression. However, there were no significantly difference on osteoblast differentiation among treatment of OA, OAA, and OAM.

• The Journal of the Petrological Society of Korea
• /
• v.27 no.1
• /
• pp.1-15
• /
• 2018

The characteristics of the rock cleavage of Jurassic Geochang granite were analysed using the distribution of microcrack lengths and spacings. The length and spacing-cumulative diagrams for the six directions of rock cleavages were arranged in increasing order ($H2{\rightarrow}R1$) on the density (${\rho}$) of microcrack length. The various parameters were extracted through the combination of above two types of diagrams. The evaluation for the six directions of rock cleavages was performed using the four groups (I~IV) of parameters such as (I) intersection angle (${\alpha}-{\beta}$), exponent difference (${\lambda}_S-{\lambda}_L$), length of line (ol and ll'), length ratio (ol/os and ll'/sl'), mean length ((ss'+ll')/2), area of right-angled triangle (${\Delta}oaa_a^{\prime}$ and ${\Delta}obb_a^{\prime}$) and area difference (${\Delta}obb^{\prime}-{\Delta}oaa^{\prime}$ and ${\Delta}obb_a^{\prime}-{\Delta}oaa_a^{\prime}$), (II) length of line (oa and os) and area (${\Delta}oaa^{\prime}$), (III) length of line (sl') and length ratio (ss'/ll') and (IV) length of line (ob, ss' and ls') and area (${\Delta}obb^{\prime}$, ${\Delta}ll^{\prime}s^{\prime}$, ${\Delta}ss^{\prime}l^{\prime}$ and ⏢ll'ss'). The results of correlation analysis between the values of parameters for three rock cleavages and those for three planes are as follows. The values of parameters for three rock cleavages are in orders of (I) H(hardway, (H1 + H2)/2) < G(grain, (G1 + G2)/2) < R(rift, (R1 + R2)/2), (II) R < G < H, (III) G < H < R and (IV) H < G < R. On the contrary, the values of parameters for three planes are in orders of (I) R' < G' < H', (II) H' < G' < R' and (III and IV) R' < H' < G'. Especially the values of parameters belonging to group I and group II show mutual reverse orders. In conclusion, this type of correlation analysis is useful for discriminating three quarrying planes.

• The Journal of the Petrological Society of Korea
• /
• v.28 no.1
• /
• pp.1-13
• /
• 2019

The characteristics of the rock cleavage of Jurassic Geochang granite were analysed using the parameters from the length and spacing-cumulative frequency diagrams. The evaluation for three planes and three rock cleavages was performed using the 25 parameters such as (1~2) slope angle(${\alpha}^{\circ}$and ${\beta}^{\circ}$), (3) intersection angle(${\alpha}-{\beta}^{\circ}$), (4) exponent difference(${\lambda}_S-{\lambda}_L$), (5~12) length of line(oa, ob, ol, os, ss', ll' and sl') and (13~15) length ratio(ol/os, ss'/ll' and ll'/sl'), (16) mean length((ss'+ll')/2), (17~23) area (${\Delta}oaa^{\prime}$, ${\Delta}obb^{\prime}$, ${\Delta}obb^{\prime}$, ${\Delta}oaa_a^{\prime}$, ${\Delta}obb_a^{\prime}$, ${\Delta}ll^{\prime}s^{\prime}$, ${\Delta}ss^{\prime}l^{\prime}$ and ⏢$ll^{\prime}ss^{\prime}$) and (24~25) area difference(${\Delta}obb^{\prime}-{\Delta}oaa^{\prime}$ and ${\Delta}obb_a^{\prime}-{\Delta}oaa_a^{\prime}$). Firstly, the values of the 11 parameters(group I: No. 1, 3~4, 7, 9~10, 13, 15~16, 20 and 25), the 3 parameters(group II: No. 5, 8 and 17) and the 2 parameters(group III: No. 12 and 22) are in orders of H(hardway) < G(grain) < R(rift), R < G < H and G < H < R, respectively. On the contrary, the values of parameters belonging to the above three groups show reverse orders for three planes. Secondly, the generalized chart for three planes and three rock cleavages were made. From the related chart, the distribution types formed by the two diagrams related to lengths and spacings were derived. The diagrams related to spacings show upward curvature in the chart of rift plane(G1 & H1, R') and hardway(H1 & H2, H). On the contrary, the diagrams related to lengths show downward curvature. These two diagrams take the form of a convex lens in the upper section. Besides, the two diagrams cross each other in the lower section. The overall shape formed by the above two diagrams between three planes($H^{\prime}{\rightarrow}G^{\prime}{\rightarrow}R^{\prime}$) and three rock cleavages($R{\rightarrow}G{\rightarrow}H$) display in reverse order. Lastly, these types of correlation analysis is useful for discriminating three quarrying planes.

• Asian-Australasian Journal of Animal Sciences
• /
• v.23 no.3
• /
• pp.312-317
• /
• 2010

Complete oxidation of fatty acid in the liver of ketotic cows was investigated. Serum non-esterified fatty acid (NEFA), beta-hydroxybutyric acid (BHBA) and glucose concentrations were measured using biochemical techniques. Carnitine palmitoyl transferase II (CPT II), 3-hydroxy acyl-CoA dehydrogenase (HAD) and oxaloacetic acid (OAA) concentrations in the liver were detected by ELISA. Serum glucose was lower in ketotic cows than controls (p<0.05). Serum BHBA and NEFA concentrations were higher in ketotic cows than controls (p<0.05). OAA, CPT II, and HAD contents in the liver of ketotic cows were lower than in controls (p<0.05). There were negative correlations between serum NEFA concentration and OAA, CPT II and HAD, but no correlation between serum BHBA concentration and capacity for complete oxidation of fatty acid. Overall, the capacity for complete fatty acid oxidation in the liver of ketotic cows might have been decreased. High serum NEFA concentrations may be unfavorable factors for the pathway of complete oxidation of fatty acid in the liver.

• The Transactions of the Korea Information Processing Society
• /
• v.4 no.9
• /
• pp.2280-2288
• /
• 1997

An agent is a software element that, by making use of knowledge and inference, performs tasks on behalf of the user. In general, an agent has the properties of autonomy, social ability, reactivity, and durability. Many researches on agents are more and more aiming at the multiagent systems since it is not sufficient to let a single agent do the whole things, especially in a real world where tasks require many diverse activities. However, the multiagent frameworks still have some limitations in the processing of user queries that are often ambiguous and goal-oriented. Also, a series of procedures or plans could not be generated from a single query directly. In order to give more intelligence to the multiagent framework, we propose a method of extending the framework with a plan generation module. The open agent architecture (OAA), which is a multiagent framework that we developed, is integrated with UCPOP, which is a AI planner. A travel schedule management agent (TSMA) system is implemented to explore the effects of the method. The extended system enables the user to only specify goal-oriented queries, and the plans and procedures to satisfy these goals are generated automatically. Also, this system provides a cooperative and knowledge-sharing environment that integrates several knowledge-based systems and planning systems that are distributed and used independently.

• Journal of Korean Library and Information Science Society
• /
• v.38 no.1
• /
• pp.257-276
• /
• 2007

The major concern of scholarly communication system that consists of libraries, researchers, and publishers is scholarly journals. But there is a huge chasm between the groups that have their own respects and strategies, compensations, and rights about scholarly journals. This difference makes open access movement which has two strategies: Open Access Journal(OAJ) and Open Access Archives (OAA). This paper describes the current status and analyses serious limitations of OAJ and OAA, especially, including the present address in the field of library and information science.

• Archives of Plastic Surgery
• /
• v.38 no.1
• /
• pp.7-14
• /
• 2011

Purpose: Many patients have fear for surgery owing to the injection of lidocaine and the possible pain in the course of the operation. To resolve such a problem the cases to do plastic surgery with monitored anesthetic care are increasing, in which something like sedatives is injected into vein without endotracheal intubation and under voluntary respiration, but the usage is now under the controversy. Methods: There were 25 patients who had surgery with local anesthesia, and another 25 patients who had surgery with monitored anesthetic care which belongs to ASA class 1 and 2 from January to April, 2009. Their anesthesia records were collected and surveys were given before and after the surgery and the surgery staff recorded OAA/S during the surgery. The postoperative surveys included the awakening during the surgery, pain, anxiety, and the degree of patient's satisfaction through visual analogue scale to identify the difference between the two methods. Results: The OAA/S results according to time lapse show that it is possible to lead a fast effective sedation and recovery with monitored anesthetic care, and monitored anesthetic care enhances both surgeon's convenience level and patient's satisfaction level, and reduces awakening, pain, and anxiety, compared to local anesthesia. Conclusion: The current paper shows about the plastic surgery, particularly the outpatient surgery, when monitored anesthetic care method is applied, it could gain a fast sedation and recovery or an effective sedation of patients. The method also has some affirmative effects in regard with surgeon's convenience and the patients' satisfaction degree and the reduction of their awakening, pain, and anxiety. With careful and adequate watch on the measures about vital signs like electrocardiogram, the degree of oxygen saturation, and blood pressure, it could clinically be very useful.

• Journal of The Korean Dental Society of Anesthesiology
• /
• v.8 no.2
• /
• pp.113-117
• /
• 2008

Background: The purpose of this study was to compare the use of midazolam only with midazolam with fentanyl or propofol in IV sedation. Methods: 24 cases were divided to midazolam group (M group), midazolam + fentanyl group (MF group), midazolam + propofol group (MP group) and midazolam + fentanyl + propofol group (MFP group). In M group, 2 ml midazolam was injected at first, than at 2 minutes interval 1-2 ml injected continuously depending on the level of sedation. In MP, MFP groups, propofol was injected at the speed of 15-20 ml/hr by infusion pump. In this study, the sedation level was evaluated by using OAA/S scale. In each groups, the recovery time was measured until OAA/S scale score level was 5, and pre and postoperative blood pressure change was measured. Each group's data was statistically analyzed using one-way ANOVA. If significant statistical difference were observed, Dunnet test was performed, and control group was M group. Results: Pre and postoperative blood pressure change were not represent significant statistical difference in 4 groups (P value = 0.679 [systolic], P value = 0.206 [diastolic]). But recovery time were represent significant statistical difference (M group: 35.6, MF group: 32.5, MP group: 17.9, MFP group: 19.6 [P value = 0.002]). The result of Dunnet test on recovery time showed significant statistical difference on MF, MFP group when M group was control group. In MFP group, sedation was increased by using supplemental fentanyl, and postoperative pain control was dominant. Conclusion: To achieve the effect of anxiolysis, analgesia, amnesia effectively, and short recovery time, MFP group is mostly recommended.