• 한국식품영양과학회지
• /
• 제46권9호
• /
• pp.1137-1142
• /
• 2017

본 연구는 고지방식이(열량의 40%를 지방으로 공급)로 유도한 비만마우스에게 아피오스 분말(10%, w/w)을 12주간 급여한 후 내장지방 감소 및 지방간 개선 효과를 살펴보았다. 아피오스 분말 급여로 인한 유의적인 체중 감소는 보이지 않았으나, 부고환지방과 후복막지방 무게가 유의적으로 감소하여 총 내장지방 무게는 대조군에 비해 14.3% 감소하였다. 부고환지방조직의 지방세포 크기 역시 아피오스 분말군에서 현저히 감소되었다. 혈청의 유리지방산, 중성지질과 총 콜레스테롤 함량은 실험군 간의 유의적인 차이가 없었으나 총 콜레스테롤에 대한 HDL-콜레스테롤 비와 동맥경화 지수는 아피오스 분말군이 대조군에 비해 각각 18.9%와 47.2% 유의적으로 개선되었다. 혈청의 렙틴 함량은 아피오스 분말군이 대조군에 비해 유의적으로 낮았다. 고지방식이를 급여한 마우스에 아피오스 분말 급여는 간 조직 중의 지질축적 및 유리지방산과 중성지질 함량을 유의적으로 낮추는 것으로 나타났다. 간 조직의 지질합성 관련 유전자인 Pparg, Fasn과 Dgat2의 발현이 아피오스 분말 급여로 억제되었다. 이상의 결과에서 아피오스 분말은 고지방식이로 인한 내장지방 축적과 지방간을 개선할 수 있을 것으로 평가되었다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제25권4호
• /
• pp.515-523
• /
• 2012

The objective of this study was to investigate the variability in broiler performance, apparent metabolisable energy (AME) and ileal digestible energy (IDE) between five different maize samples fed with and without xylanase at 16,000 U/kg. Various in vitro characterisations were conducted to determine if any could predict performance or AME. Samples of the maize were harvested in five diverse regions and fed individually in a mash diet as follows (g/kg): test maize 608.3; soya bean meal (SBM) 324.1; poultry fat 25.2; salt 4.6; met 2.6; lys 1.6; thr 0.5; limestone 9.7, dical 18.4; vit/min 5.0; CP 210 and ME (kcal/kg) 3,085. The diets were fed to 720 broilers with 6 replicates, each containing 12 birds per treatment, from 0 to 18 d of age. Maize samples were analysed for starch, protein, crude fibre, fat, protein solubility index (PSI) and vitreousness using near infra red reflectance spectroscopy (NIR). They were also assayed using an in vitro starch digestibility method. The results showed that there was no effect of harvest region on the feed intake (FI), body weight gain (BWG) or feed conversion ratio (FCR) of the broilers over the 18 d period (p = 0.959, 0.926, 0.819 respectively). There was an improvement in all parameters with the addition of xylanase (FI p = 0.011; BWG and FCR p<0.001). There was a significant positive effect of xylanase on IDE, AME, IDE Intake (IDEI) and AME intake (AMEI) (p<0.0001 in all cases). Although there was no significant effect of maize source, there was a strong trend towards variability in IDE (p = 0.066) and AME (p = 0.058). There were no significant correlations (p<0.05) between any proximate or physiochemical values and any performance or AME values. This may suggest that none of those selected were suitable predictors for performance or AME. The broilers performed well according to the breed guidelines, with slightly increased FI, increased BWG and similar FCR prior to the addition of xylanase. When FCR and BWG were analysed with FI as a covariate, xylanase addition remained significant suggesting that the improvement in BWG and FCR was driven by an increase in digestibility and nutrient availability.

• Asian-Australasian Journal of Animal Sciences
• /
• 제27권6호
• /
• pp.886-897
• /
• 2014

The aim of the present study was to get a total physical and chemical characterization and comparison of the principal components in Bangladeshi buffalo (B), Holstein cross (HX), Indigenous cattle (IC) and Red Chittagong Cattle (RCC) milk. Protein and casein (CN) composition and type, casein micellar size (CMS), naturally occurring peptides, free amino acids, fat, milk fat globule size (MFGS), fatty acid composition, carbohydrates, total and individual minerals were analyzed. These components are related to technological and nutritional properties of milk. Consequently, they are important for the dairy industry and in the animal feeding and breeding strategies. Considerable variation in most of the principal components of milk were observed among the animals. The milk of RCC and IC contained higher protein, CN, ${\beta}$-CN, whey protein, lactose, total mineral and P. They were more or less similar in most of the all other components. The B milk was found higher in CN number, in the content of ${\alpha}_{s2}-$, ${\kappa}$-CN and ${\beta}$-lactalbumin, free amino acids, unsaturated fatty acids, Ca and Ca:P. The B milk was also lower in ${\beta}$-lactoglobulin content and had the largest CMS and MFGS. Proportion of CN to whey protein was lower in HX milk and this milk was found higher in ${\beta}$-lactoglobulin and naturally occuring peptides. Considering the results obtained including the ratio of ${\alpha}_{s1}-$, ${\alpha}_{s2}-$, ${\beta}$- and ${\kappa}$-CN, B and RCC milk showed best data both from nutritional and technological aspects.

• Korean Chemical Engineering Research
• /
• 제55권4호
• /
• pp.567-573
• /
• 2017

선박용 경유(황 농도 약 230 ppmw)의 황화합물 제거를 위해 산화텅스텐($WO_x$)을 실리카로 이루어진 다공성 물질인 SBA-15에 담지한 산화 촉매를 제조하였으며 산화제로 과산화수소를 이용한 산화공정과 추출 용매로 아세토니트릴을 이용한 추출공정을 통해 촉매의 산화성능을 확인하였다. XRD 및 XRF, XPS 분석과 BET 이론을 통해 제조한 촉매의 물리적 특성에 대해 조사하였다. 담지된 $WO_x$는 삼산화텅스텐($WO_3$)으로 존재하였으며 실제 담지율이 약 10 wt% 부근일 때 단일층을 형성하는 것으로 판단된다. 제조한 촉매의 산화성능을 확인한 결과, 0.1 g의 13 wt% $WO_x$/SBA-15 촉매와 과산화수소(산소/황 몰 비=10)를 도입하여 $90^{\circ}C$에서 3시간 동안 반응이 이루어졌을 때 76.3%의 가장 높은 황 제거율을 나타냈다. 연속반응 비교 실험을 통해 1회의 산화반응으로 황 화합물의 산화가 충분히 일어났음을 확인하였다. 또한 5회의 추출공정을 통해 최대 94.4%의 황 제거율을 나타냈다.

• 한국토양비료학회지
• /
• 제42권2호
• /
• pp.98-102
• /
• 2009

유기농재배농가 토양관리 실태와 토양의 물리화학적 특성을 조사하고 분석한 결과를 요약하면 다음과 같다. 유기농 밭 토양은 인근대비 용적밀도와 경도의 개선효과가 있었고, 특히 공극률, 소형판침하량, 표토심, 경운심, 근권심은 높게 나타났다. 내수성입단은 유기농재배 밭이 인근농가 밭보다 오히려 낮았다. 이는 유기농가에서 염류집적을 고려하여 파쇄목, 나무껍질, 수피 등과 같은 C/N율이 높은 거친 유기물들을 시용하였기 때문인 것으로 생각된다. 유기농재배 밭의 유효인산 및 치환성양이온 함량 등의 토양화학성은 대부분 인근농가에 비해 높게 나타났는데, 이는 유기물을 과량 시용하였기 때문으로 분석되었다.

• Toxicological Research
• /
• 제29권1호
• /
• pp.21-25
• /
• 2013

The selective targeting of an integrin ${\alpha}_v{\beta}_3$ receptor using radioligands may enable the assessment of angiogenesis and integrin ${\alpha}_v{\beta}_3$ receptor status in tumors. The aim of this research was to label a peptidomimetic integrin ${\alpha}_v{\beta}_3$ antagonist (PIA) with $^{99m}Tc(CO)_3$ and to test its receptor targeting properties in nude mice bearing receptor-positive tumors. PIA was reacted with tris-succinimidyl aminotriacetate (TSAT) (20 mM) as a PIA per TSAT. The product, PIA-aminodiacetic acid (ADA), was radiolabeled with $[^{99m}Tc(CO)_3(H_2O)_3]^{+1}$, and purified sequentially on a Sep-Pak C-18 cartridge followed by a Sep-Pak QMA anion exchange cartridge. Using gradient C-18 reverse-phase HPLC, the radiochemical purity of $^{99m}Tc(CO)_3$-ADA-PIA (retention time, 10.5 min) was confirmed to be > 95%. Biodistribution analysis was performed in nude mice (n = 5 per time point) bearing receptor-positive M21 human melanoma xenografts. The mice were administered $^{99m}Tc(CO)_3$-ADA-PIA intravenously. The animals were euthanized at 0.33, 1, and 2 hr after injection for the biodistribution study. A separate group of mice were also co-injected with 200 ${\mu}g$ of PIA and euthanized at 1 hr to quantify tumor uptake. $^{99m}Tc(CO)_3$-ADA-PIA was stable in phosphate buffer for 21 hr, but at 3 and 6 hr, 7.9 and 11.5% of the radioactivity was lost as histidine, respectively. In tumor bearing mice, $^{99m}Tc(CO)_3$-ADA-PIA accumulated rapidly in a receptor-positive tumor with a peak uptake at 20 min, and rapid clearance from blood occurring primarily through the hepatobiliary system. At 20 min, the tumor-to-blood ratio was 1.8. At 1 hr, the tumor uptake was 0.47% injected dose (ID)/g, but decreased to 0.12% ID/g when co-injected with an excess amount of PIA, indicating that accumulation was receptor mediated. These results demonstrate successful $^{99m}TC$ labeling of a peptidomimetic integrin antagonist that accumulated in a tumor via receptor-specific binding. However, tumor uptake was very low because of low blood concentrations that likely resulted from rapid uptake of the agent into the hepatobiliary system. This study suggests that for $^{99m}Tc(CO)_3$-ADA-PIA to be useful as a tumor detection agent, it will be necessary to improve receptor binding affinity and increase the hydrophilicity of the product to minimize rapid hepatobiliary uptake.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
• /
• pp.433-433
• /
• 2012

As the requirement in patterning geometry continuously shrinks down, the termination of etch process at the exact time became crucial for the success in nano patterning technology. By virtue of real-time optical emission spectroscopy (OES), etch end point detection (EPD) technique continuously develops; however, it also faced with difficulty in low open ratio etching, typically in self aligned contact (SAC) and one cylinder contact (OCS), because of very small amount of optical emission from by-product gas species in the bulk plasma glow discharge. In developing etching process, one may observe that coupon test is being performed. It consumes costs and time for preparing the patterned sample wafers every test in priority, so the coupon wafer test instead of the whole patterned wafer is beneficial for testing and developing etch process condition. We also can observe that etch open area is varied with the number of coupons on a dummy wafer. However, this can be a misleading in OES study. If the coupon wafer test are monitored using OES, we can conjecture the endpoint by experienced method, but considering by data, the materials for residual area by being etched open area are needed to consider. In this research, we compare and analysis the OES data for coupon wafer test results for monitoring about the conditions that the areas except the patterns on the coupon wafers for real-time process monitoring. In this research, we compared two cases, first one is etching the coupon wafers attached on the carrier wafer that is covered by the photoresist, and other case is etching the coupon wafers on the chuck. For comparing the emission intensity, we chose the four chemical species (SiF2, N2, CO, CN), and for comparing the etched profile, measured by scanning electron microscope (SEM). In addition, we adopted the Dynamic Time Warping (DTW) algorithm for analyzing the chose OES data patterns, and analysis the covariance and coefficient for statistical method. After the result, coupon wafers are over-etched for without carrier wafer groups, while with carrier wafer groups are under-etched. And the CN emission intensity has significant difference compare with OES raw data. Based on these results, it necessary to reasonable analysis of the OES data to adopt the pre-data processing and algorithms, and the result will influence the reliability for relation of coupon wafer test and whole wafer test.

• 한국작물학회지
• /
• 제27권1호
• /
• pp.11-19
• /
• 1982

본 시험은 이화명충에 대한 경종적 방제법 확립의 가능성 검토의 일환으로서 합리적 시비가 이화명충 발육과 생존.피해 및 우화억제 등에 미치는 효과를 구명하고자 아끼바레와 밀양 2003를 공시하여 규산과 질소의 시비수준을 달리한 Pot시험을 실시하였던 바 그 결과를 요약하면 다음과 같다. 1. 1화기의 유충체중.유충생존율ㆍ피해 등은 밀양 2003에서 아끼바레보다 모두 높았다. 그러나 규산ㆍ질소처리수준간에는 그 차가 인정되지 않았고 우화율은 품종간의 차이뿐만 아니라 규산 수준간의 차이도 인정되었다. 2. 2화기의 유충체중은 아끼바레에서 밀양 2003보다 낮았으며 높은 질소수준에서 높았고, 품종과 규산수준 및 질소 및 규산 수준간의 교호작용이 인정되었다. 3. 2화기 유충의 생존율은 아끼바레가 낮았고 규산시용량을 증가시킬수록 낮아졌으며 경의 규질비와 유충생존율과의 사이에는 높은 부의 상관관계가 나타났다. 4. 백수피해는 품종간의 차이보다 규산시용수준간의 차이가 더 컸지만 아끼바레에서 그리고 규산시용량이 많은 구에서 피해가 적었다. 경의 규산비와 백수율과의 상관관계는 두 품종 모두 높은 부의 상관을 나타냈다. 5. 월동유충의 우화율은 규산시용수준간의 차이가 품종간의 차이보다 월등히 높았는데 밀양2003보 아끼바레에서 낮았고, 규산시용량이 많아질수록 감소하였으며 규산비의 우화율과의 사이에는 높은 부의 상관을 나타냈다. 특히 규산을 시용치 않은 질소 20kg/10a구에서 우화율은 급격히 높아졌다.

• 유기물자원화
• /
• 제10권2호
• /
• pp.92-99
• /
• 2002

본 연구는 phyllite를 수분조절제로서 이용한 퇴비에 대하여 작물에 대한 효용성 평가 및 토양의 이화학적 특성변화를 규명하기 위해 수행되었다. Phyllite 퇴비의 물리성과 화학성 및 부숙도와 안정성을 평가하기 위한 작물재배시험과 토양의 이화학적 특성변화의 실험결과 상추 및 열무의 생육 및 수확량은 PSPC10에서는 20 Mg/ha의시용량이, PSPC20에서 10 Mg/ha이 가장 좋았으며 다른 비해는 나타나지 않았다. 또한 토양의 이화학적 특성변화는 퇴비의 EC값이 높기 때문에 시비한 토양의 EC가 초기보다 높게 상승하였으며, 퇴비의 40 Mg/ha을 처리한 토양에서는 EC 값이 2dS/m 이상으로 나타났다. 공시작물인 열무와 상추의 재배시험에서는 상추의 경우가 유효인산 및 EC가 크게 증가하였다. 열무의 경우는 질소, 유기물과 EC의 함량은 시험전보다 감소하였으며 이것은 열무의 질소 이용율이 높음을 알 수 있다. 토양 물리성의 변화는 phyllite의 첨가량이 많은 퇴비일수록 용적밀도가 낮아지며 토양의 수분보유력이 증가하였다. phyllite를 이용한 퇴비를 토양에 시용하였을 경우 작물의 비해는 없었으며, 토양의 이화학적인 특성변화에서도 우려할 만한 사항은 없는 것으로 보아 phyllite를 이용한 퇴비의 활용기능성이 크다고 판단된다.

• 한국대기환경학회지
• /
• 제34권4호
• /
• pp.554-566
• /
• 2018

The rice husk contains nutrients which can be easily utilized by microorganisms, and also has a water retaining ability, which played a crucial part in enabling it to become a biofilter media. In this study, we evaluated the applicability of rice husk pellet bio-scrubber as a microbiological carrier. The pelletization experiment of rice husk as a biological media was performed using PVA and EVA binder. Also, the feasibility tests of rice husk as a biological media for odor removal were carried out in order to know whether rice-husk contains useful components as a media for microbiological growth or not. Lastly, a combined test for odor gas absorption and biological oxidation was conducted using a lab scale bio-filter set-up packed with rice-husk pellets as wet-scrubber. The major components of the rice husk were carbon, hydrogen, nitrogen, and oxygen, while carbon acted as the main ingredient which comprised up to 23.00%. The C : N : P ratio was calculated as 45 : 1 : 2. Oxygen uptake rate, yield and decay rate of the rice husk eluent was calculated to be $0.0049mgO_2/L/sec$, 0.24 mgSS/mgCOD and 0.004 respectively. The most stable form of rice husk pellets was produced when the weight of the rice husk, EVAc, PVAc, and distilled water was 10 : 2 : 0.2 : 10. The prepared rice husk pellets had an apparent density of 368 g/L and a porosity of 59.00% upon filling. Dry rice husks showed high adsorption capacity for ammonia gas but low adsorption capacity for hydrogen sulfide. The bio-filter odor removal column filled with rice husk pellets showed more than 99.50% removal efficiency for NH3 and H2S gas. Through the analysis of circulation water, the prime removal mechanism is assumed to be the dissolution by water, microbial nitrification, and sulfation. Finally, it was confirmed that the microorganisms could survive well on the rice husk pellets, which provided them a stable supply of nutrients for their activity in this long-term experiment. This adequate supply of nutrients from the rice husk enabled high removal efficiency by the microorganisms.