• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2017년도 춘계 학술논문 발표대회
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• pp.5-6
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• 2017

Ultra high-strength concrete can prevent spalling by mixed ratio of PP and NY fiber. However, there is a lack of research on the deterioration of strength due to changes in mechanical properties after spalling prevention. In this study, the effect of high temperature on the mechanical properties of 150MPa concrete mixed with PP and NY fiber was evaluated. As a result, mixing PP and NY fiber is judge to be little effect on the mechanical properties of the 150MPa concrete at high temperature.

• 생명과학회지
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• 제19권7호
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• pp.886-891
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• 2009

Cancer/testis(CT) antigens은 여러 종료의 암에서는 발현이 되지만, 정상조직에서는 고환에서만 발현이 되는 특이성을 가지고 있다. 이러한 특이성은 immunotherapy을 하기 위한 항암백신 개발에 매력적인 유전자로 알려져 있다. 본 연구에서는 29개의 한국유방암조직에서 13개의 CT antigens (NY-SAR35, SCP-1, SSX-1, SSX-2, SSX-4, MAGE-1, MAGE-3, MAGE-4, MAGE-10, CT-7, NY-TLU57, NY-ESO-1, and LAGE-1)의 발현빈도를 RT-PCR을 통하여 조사하고 환자의 임상학적 분류와 CT antigens의 발현빈도에 대하여 조사하였다. 29개의 유방암조직에 RT-PCR결과, 13개의 CT antigen중에 MAGE-3 (66%)와 MAGE-1(57%)에서 발현빈도가 가장 높았고 LAGE-1 (55%),NY-SAR-35 (49%),MAGE-4(41%), NY-ESO-1(38%), CT-7(24%), SSX-4(24%)순으로 발현빈도를 보였다. 그러나 SSX-1, SSX-2. MAGE-10와 NY-TLU-57의 발현은 3-7%로 매우 낮았고 특히 SCP-1는 발현되지 않았다. 29 유방암 조직에서 적어도 하나 이상의 CT antigen이 발현되는 샘플은 28(98%)이였다. 그러나 환자의 임상학적 분류와 CT antigens의 발현빈도와는 특징적인 관꼐가 없음을 알수있었다. 29개의 유방암조직에서 MAGE-3와 NY-ESO-1의 Protein level에서의 발현을 알아보기 위하여monoclonal antibody를 이용하여 면역조직염색을 하였다. MAGE-3은 29개 조직중에서 12개의 조직에서 발현되었으며 NY-ESO-1은 11개의 조직에서 발현되었다. 그러므로 CT antigens은 한국 유방암 조직에서 빈번하게 발현된 것을 알 수 있었으며 CT antigens을 기반으로 한 암 백신개발의 잠재적인 표적이 될 수 있을 것이라 사료된다.

• 대한한의학회지
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• 제29권5호
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• pp.1-13
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• 2008

Objective : This study is investigate the effects of Sagunjatang-Ga-Nokyong(SGJ-NY) treatment on regenerative responses of corticospinal tract(CST) axons in the injured spinal cord. Methods :Using rats, we damaged their spinal cord, and then applied SGJ-NY extract to the lesion. Then we observed GAP-43 and NGF protein, astrcyte, axonal regeneration responses and axonal elongation. Result :Determination of GAP-43 and NGF protein levels were increased. And increased proliferation of astrocyte and enhanced processes in astrocytes were observed by SGJ-NY treatment. Higher number of astrocytes within the injury cavity in SGJ-NY treated group were showed, yet CSPG proteins were a weaker staining in the cavity in SGJ-NY. CST axons extended into the cavity and to the caudal area in SGJ-NY treated group were increased. Conclusion : SGJ-NY treatment might increase neural activity in the injured spinal cord tissue, and improved axonal regeneration responses. In this process, activation of astrocytes may play a role in promoting enhanced axonal elongation. the current study show that SGJ-NY exerts positive activity on inducing nerve regeneration responses by elevating neural tissue migration activities.

• 한국독성학회:학술대회논문집
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• 한국독성학회 1997년도 국제 심포지움 및 춘계 학술대회
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• pp.65-74
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• 1997

By using guinea pig lung mast cells, this study aimed to examine the effects of Aloe component(NY945) on the mediator releases caused by mast cell activation, and also aimed to assess the effects of NY945 on the mechanism of mediator releases in the mast cell activation. We partially purified mast cells from guinea pig lung tissues by using the enzyme digestion, the rough and the discontinuous density percoll gradient method. Mast cells were sensitized with $IgG_1$ (anti-OA) and challenged with ovalbumin. Histamine was assayed by fluorometric analyzer, leukotrienes by radioimmunoassay The phospholipase D activity was assessed more directly by the production of labeled phosphatidylethanol or phosphatidylbutanol which was produced by phospholipase D-mediated transphosphatidylation in the presence of ethanol or butanol. The amount of mass 1,2-diacylglycerol was measured by the [$^3H$]1,2-diacylgycerol produced when prelabeled with [$^3H$]myristic acid. In the mast cells prelabeled with L-[$^3H$]methyl methionine the phospholipid methylation was assessed by measuring the incorporation of the [$^3H$]methyl moiety into phospholipids. Pretreatment of NY945(10$\mu$g) significantly decreased histamine and leukotrienes releases during mast cell activation. The decrease of histamine release was stronger than that of leukotrienes during mast cell activation. The phospholipase D activity increased by the mast cell activation was decreased by the dose-dependent manner in the pretreatment of NY945. The amount of mass 1,2-diacylglycerol produced by activation of mast cells were decreased in the pretreatment of NY945. NY945 pretreatment strongly inhibited the incorporation of the [$^3H$]methyl moiety into phospholipids. The data suggest that NY945 purified from Aloe inhibits in part an increase of 1,2-diacylglycerol which is produced by activating mast cells with antigen-antibody complexes which is mediated via phosphatidylcholine-phospholipise D and phosphatidylinositole-phospholipise C systems, and then followed by the inhibition of histamine release. Furthermore, NY945 reduces the phosphatidylcholine production by inhibiting the methyltransfsrase I and II, which decrease the conversion of phosphatidylcholine into arachidonic acid and inhibits the production of leukotrines.

• 한국식품조리과학회지
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• 제26권3호
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• pp.300-306
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• 2010

Arabica coffee has been classified for trading according to the New York Board of Trade (NYBOT) green coffee classification. The aim of the present study is to evaluate the physiochemical and sensorial characteristics of coffees classified by NYBOT as NY2 (specialty coffee), NY3/4 and NY4/5 (commercial coffee). The density of green coffee was higher for the NY2 sample. The amount of total solids in brewed coffee increase as the green coffee grade decreased and the pH levels decreased as the coffee grade decreased. Descriptive analysis using a 15cm line scale was carried out by 12 trained panelists prepared by espresso coffee and consumer preference tests were carried out by 168 consumers. The NY2 sample had the highest fruity, acidity, sweetness and aftertaste characteristics. In addition, green, rio, sour and astringency characteristics increased as the coffee grade decreased. Acceptance of aroma, flavor, taste balance and overall were higher for the NY2 sample. In the consumer preference test, the NY2 and NY4/5 samples had a similar distribution, but consumers between the ages of 20 to 30 who like to drink brewed coffee more than instant coffee preferred the NY2 than sample over the NY3/4 sample. In conclusion, significant differences were observed among the three groups of green coffee classification in all physicochemical and sensory parameters.

• 콘크리트학회논문집
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• 제22권4호
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• pp.473-479
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• 2010

이 연구에서는 도로포장용 콘크리트의 성능향상을 목적으로 폴리프로필렌(PP), 나일론(NY), 폴리비닐알코올(PVA) 및 셀룰로우스(CL)의 섬유 종류에 변화를 주어 도로포장용 섬유보강 콘크리트(FRC)의 공학적 특성을 분석하였다. 그 결과 굳지 않은 콘크리트의 특성으로 유동성은 OPC에 비해 섬유를 혼입할 경우 저하하는 경향을 나타내었으나, 혼합 즉시는 PP섬유, 60분 경시변화까지도 고려하면 NY섬유에서 가장 우수한 것으로 나타났다. 공기량은 OPC와 유사한 경향을 나타내며, 섬유 혼입으로 인한 공기량의 변화는 크지 않았다. 경화 콘크리트의 특성으로 압축강도 및 휨강도는 Plain에 비하여 모든 재령에서 섬유를 혼입할 경우 증가하는 경향을 나타내었는데, 섬유 종류별로는 NY, PVA, PP, CL순이었다. 단, 인장강도에서는 NY 및 PP일 경우만 증가하는 경향이었다. 포로시미터에 의한 세공분포는 NY섬유를 혼입할 경우 섬유의 영향으로 $1{\mu}m$ 전후의 세공량이 많이 분포하여 누적 세공량이 커지는 경향을 나타내었다. 따라서 유동성 및 강도 등을 종합적으로 고려할 때, 이 연구의 실험 조건에서는 NY섬유 혼입 시 최상의 결과가 도출되는 것으로 분석되었다.

• The Plant Pathology Journal
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• 제17권6호
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• pp.373.2-373
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• 2001

• 한국식품조리과학회지
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• 제18권5호
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• pp.522-528
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• 2002

The effects of packaging materials, Ny/PE, PET/PE/Al, PET/PE/LDPE/CPP, and PET/Al/Ny/CPP, and packaging methods, atmospheric and vacuum packaging on physicochemical properties of onion Kimchi and rosemary-onion Kimchi were investigated. The maximun swelling days of packaging materials were increased more in rosemary-onion Kimchi than in onion kimchi, and they were in the order of PET/Al/Ny/CPP, PET/PE/Al, PET/PE/LDPE/CPP, and Ny/PE. The pH and reducing sugar contents of onion Kimchi and rosemary-onion Kimchi were decreased during storage. and those of lion Kimchi and rosemary-onion Kimchi packaged in PET/Al/Ny/CPP were higher than those in different packaging materials. Titratible acidity and vitamin C content of rosemary-onion Kimchi were lower than those of onion Kimchi, but there were no differences in the L and b values between two groups.

• 한국식품과학회지
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• 제26권1호
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• pp.62-67
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• 1994

김치를 Ny/PE, Ny/CPP(PP tray+Ny/CPP cover), Cryovac BK-1, BK-4, PET/Al/PE film으로 포장하여 $5^{\circ}C$ (97%RH), $20^{\circ}C$ (76%RH)에서 저장 중 품질변화를 살펴보았다. 김치의 품질을 평가하기 위하여 포장내 가스조성, pH, 산도, 색도, 젖산균 수, 기호도를 기간별로 측정하였다. 포장내 가스조성은 PET/Al/PE film 포장김치가 저장초기에 산소농도가 높았고, 저장말기에 이산화탄소농도가 거의 100% 수준에 달하였다. Cryovac BK-1, BK-4로 포장된 김치는 발효가 진행되면서 이산화탄소농도가 증가하다가 가스투과성에 의한 이산화탄소의 방출과 외부공기의 유입으로 산소농도는 증가하고 이산화탄소농도는 감소하는 형태를 보였으며 저장말기까지 Ny/PE, Ny/CPP, PET/Al/PE와는 달리 포장의 팽배화 현상은 나타나지 않았다. pH 변화는 포장재질에 따른 차이가 크지 않았으나 Cryovac BK-1, BK-4가 저장중 다른 포장재질에 비하여 약간 낮은 pH를 나타냈으며, 산도는 약간 높았다. 저장중 김치의 색도변화가 포장재질에 따라 달랐으며, 포장재질별 젖산균수, 기호도 변화는 저장온도 모두에서 유의적인 차이가 없는것으로 나타났다. 이상의 결과를 종합하여 본 실험에 사용한 포장재질이 김치의 품질에 미치는 영향은 크게 다르지 않다고 여겨졌고, 저장 및 유통시 문제점인 팽배화현상을 방지하기 위해서는 현재 업체에서 사용하는 기체차단성이 높은 포장재보다는 상대적으로 이산화탄소의 투과도가 높은 포장재의 사용이 바람직하다고 사료된다.

• The Korean Journal of Physiology and Pharmacology
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• 제2권1호
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• pp.119-131
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• 1998

It has been reported that the glycoprotein extracted from Aloe has strong anti-inflammatory response. However, there has been no research report yet about the effect of Aloe on allergic hypersensitivity reactivity. By using guinea pig lung mast cells, this study aimed to examine the effects of Aloe glycoprotein (NY945) on the mediator releases caused by mast cell activation, and also aimed to assess the effects of NY945 on the mechanism of mediator releases in the mast cell activation. We partially purified mast cell from guinea pig lung tissues by using the enzyme digestion, the rough and the discontinuous density percoll gradient method. Mast cells were sensitized with IgG1 (anti-OA) and challenged with ovalbumin. Histamine was assayed by fluorometric analyzer, leukotrienes by radioimmunoassay. The phospholipase D activity was assessed by the production of labeled phosphatidylalcohol. The amount of mass 1, 2-diacylglycerol (DAG) was measured by the $[^3H]DAG$ produced when prelabeled with $[^3H]myristic$ acid. The phospholipid methylation was assessed by measuring the incorporation of the $[^3H]methyl$ moiety into phospholipids of cellular membranes. Pretreatment of NY945 (10 ${\mu}g$) significantly decreased histamine and leukotrienes releases during mast cell activation. The decrease of histamine release was stronger than that of leukotriene during mast cell activation. The phospholipase D activity increased by the mast cell activation was decreased by the dose-dependent manner in the pretreatment of NY945. The amount of DAG produced by PLC activity was decreased by NY945 pretreatment. The amount of mass 1, 2-diacylglycerol produced by activation of mast cells was decreased in the pretreatment of NY945. NY945 pretreatment strongly inhibited the incorporation of the $[^3H]methyl$ moiety into phospholipids. The data suggest that NY945 purified from Aloe inhibits in part an increase of 1, 2-diacylglycerol which is produced by activating mast cells with antigen-antibody reactions, which is mediated via phosphatidylcholine-phospholipase D and phosphatidylinositol-phospholipase C systems, and then followed by the inhibition of histamine release. Furthermore, NY945 reduces the production of phosphatidylcholine by inhibiting the methyltransferase I and II, which decreases the conversion of phosphatidylcholine into arachidonic acid and inhibits the production of leukotrienes.