• Journal of Life Science
• /
• v.24 no.9
• /
• pp.1030-1038
• /
• 2014

Platelet products are used to treat hemorrhagic or platelet dysfunction diseases. Plateletpheresis involves collecting the platelet components of blood using an apheresis blood-collection system. Various indicators are available for evaluating the qualities of the apheresis platelets. The productivity of platelet collection is evaluated through both the collection efficiency and collection rates. Platelet storage quality can be evaluated in vitro using several indicators, including visual appearance, metabolic activities, volume, platelet count, white blood cell count, microparticles, and various platelet activation markers. Platelet activation markers have been used as indicators of storage quality in various studies. Post-transfusion platelet quality can be evaluated based on the corrected count increment and the percentage of platelet recovery. Although various studies have investigated the aspects of plateletpheresis, no article has systemically presented assessments of the platelet products obtained from different plateletpheresis devices. The present study provides a review of plateletpheresis, including the specifics of the process, the types of devices employed, the platelet quality, the overall efficacy, and the evaluation indicator qualities. Furthermore, the differences in functionality among the different apheresis devices are discussed. Although adverse reactions to the citrate anti-coagulant have been reported, apheresis processing may provide a safer option for donors who are at a high risk for presyncopal or syncopal reactions related to whole blood collection.

• Biomedical Science Letters
• /
• v.26 no.1
• /
• pp.47-50
• /
• 2020

Recently, decades of robust researches on degenerative brain disorder have been highlighted on the interactive connection of gut and brain. In terms of inflammatory cytokine production, others have shown that Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) is involved with Leucine-Rich Repeat Kinase 2 (LRRK2). HEK293T cells were transiently co-transfected with Myc-tagged LRRK2 and Flag-tagged NOD2 and then followed by co-immunoprecipitation assay. In this study, we provide the novel finding of physical protein-protein interaction between NOD2 and LRRK2. G2019S variant has shown stronger interactions against NOD2 than those of wild type LRRK2. In an axis of NOD2-LRRK2 communication, it is believed to pave a new way in the understanding of the bidirectional molecular mechanism of brain disorder, including Parkinson's disease into gut inflammatory disease, including Crohn's disease.

• Perspectives in Nursing Science
• /
• v.9 no.2
• /
• pp.111-118
• /
• 2012

Purpose: This study investigated the effects of simulation-based nursing education (for the care of congestive heart failure patients) on self-directed learning competency, clinical knowledge and problem-solving ability among nursing students. Methods: A one-group, pre-post design was utilized with 87 nursing students as the subjects. The scenario of simulation-based nursing education was created using a high-fidelity patient stimulator, and consisted of four states ((1) assessment, (2) reviewing laboratory data and administering medications and treatments, (3) managing increased dyspnea and decreased urine output, and (4) handling the "getting better" state). The simulation-based nursing education included orientation, team-based learning, team-based practice, and debriefing. The data were analyzed using descriptive statistics, Pearson's correlation coefficients and paired t-tests. Results: The scores on the factors for self-directed learning competency (t=-2.57, p= .011), clinical knowledge (t=-6.85, p<.001), and problem-solving ability (t=-3.01, p= .003) increased significantly after the education intervention. Conclusion: Simulation-based nursing education is useful in improving self-directed learning competency, clinical knowledge, and problem-solving ability in nursing students.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.5
• /
• pp.412-420
• /
• 2016

This study examined the effects of open laboratory self-directed practice on knowledge, self-confidence, and skill competency of intramuscular injection in nursing students. This was a quasi-experimental study using a non-equivalent control group pre-posttest design, and the participants were 32 students comprising an experimental group and 30 students comprising a control group. The experimental group was allowed to perform an open laboratory self-directed practice and traditional practice, and the control group performed traditional practice only. The score of knowledge of the control group was significantly higher than that of the experimental group (F=3.59, p=.019), and those of the self-confidence (F=2.26, p=.016) and skill competency (F=9.08, p<.001) of the experimental group were significantly higher than those of the control group. Open laboratory self-directed practice was effective in improving the nursing students' self-confidence and skill competency. Therefore, students should be encouraged to actively participate in open laboratory self-directed practice and the effective strategies should be developed.

• The Journal of Korean Academic Society of Nursing Education
• /
• v.13 no.1
• /
• pp.13-22
• /
• 2007

Purpose: The purpose of this study was to determine learning styles and preferred learning methods of undergraduate nursing students in Korea. Method: Data was collected from 724 nursing students at five universities in Seoul, Busan, Daegu, Daejeon, and Gwangju. Kolb's Learning Style Inventory, a self-report questionnaire was completed. Result: Learning styles of nursing students were diverger 43.5%, accommodator 36.7%, assimilator 10.8%, or converger 9.0% Learning styles were significantly different related to preferred future clinical practice area and grade. Furthermore, active experimentation(AE) learning mode was significantly different by grade. Concrete experience(CE), conceptualization(AC), and active experimentation(AE) learning modes were significantly different preferred future clinical practice area. preferred learning methods were lecture 40.7%, clinical practice 37.2%, self-directed learning 8.7%, laboratory practice 8.0%, and group discussion 5.4%. Preferred learning methods were significantly different by learning styles and grade. Lecture was preferred in diverger and assimilator. Clinical practice was preferred in accommodator and converger. Styles Conclusion: This study suggested that nursing education should be applied to nursing students after examining learning styles and preferred learning methods. In conclusion, nursing educators should help to develop various learning modes for student's balanced learning capabilities.

• Journal of the Korean Institute of Oriental Medical Informatics
• /
• v.21 no.2
• /
• pp.1-9
• /
• 2015

Purpose: This study was conducted to investigate the perceived image of nurses on major and non-major students. Methods: The subjects were 120 nursing school students and 120 other university students in J province. The data was collected by using structured questionnaire. T-test, ANOVA were performed by SPSS/PC 20.0. Results: The score for image of nurses was as follows. special image($3.86{\pm}0.51$), traditional image($3.71{\pm}0.53$), individual image($3.53{\pm}0.85$), social image($3.43{\pm}0.58$), and grand mean($3.66{\pm}0.48$). Perceived image of nurses was significant difference between students of a major and non-major(t=6.390, p<.001). Conclusion: It is needed to monitoring of media for the improvement the perceived image of nurses and also nurses have to try to make an individual role model.

• Journal of Korean Academy of Fundamentals of Nursing
• /
• v.23 no.3
• /
• pp.292-299
• /
• 2016

Purpose: The purpose of this study was to provide a basis for improvement and enhancement of nursing education by investigating learning outcomes that apply to fundamentals of nursing and teaching methods used in classes. Methods: Data were collected from 111 professors of fundamentals of nursing who responded to the self-report questionnaire. Data were analyzed using chi-square test. Results: For learning outcomes in fundamentals of nursing the most frequent number of outcomes was two (35.2%), or three (32.4%). For learning outcomes in fundamentals of nursing practicum, the most frequent number of outcomes was two (32.4%), or three (31.6%). In fundamental nursing classes, teaching methods used most frequently were lectures (98.2%) and videos (60.4%), and in practice classes, demonstration (98.2) and open laboratory (90.9%). Constructivist teaching methods that were utilized in fundamental nursing were team-based learning (19.8%) and case-based learning (19.8%), and for practice classes, objective structured clinical examination (29.7%). In the cross analysis, 28.8% of the nursing professor used the constructivist teaching methods in fundamental nursing and in practice classes. Conclusion: There is a need to continue to improve teaching methods for new nurse-educators and professors and to discuss learning outcomes of fundamental nursing.

• Child Health Nursing Research
• /
• v.29 no.3
• /
• pp.218-228
• /
• 2023

Purpose: This study aimed to identify clinical characteristics of South Korean pediatric inflammatory bowel disease (IBD) in a children's hospital over the past 5 years, with a specific focus on comparing the features observed between Crohn's disease (CD) and ulcerative colitis (UC). Additionally, it aimed to examine the nursing diagnoses given to patients. Methods: This retrospective study analyzed the medical records of Korean pediatric patients under 18 years of age who were diagnosed with IBD and hospitalized at a children's hospital in Seoul, South Korea, from January 2017 to December 2021. Results: The number of pediatric patients diagnosed with IBD steadily increased. This finding was particularly prominent for CD patients, the majority of whom were male. Pediatric patients with CD had significantly higher rates of abdominal pain and perianal lesions, while pediatric patients with UC had a higher rate of bloody stool. Laboratory findings indicated that CD patients had higher levels of inflammatory markers and lower albumin levels than UC patients. The nursing diagnoses given during hospitalization mostly related to safety and protection, physical comfort, and gastrointestinal function. Conclusion: This study provides insights into Korean pediatric IBD patients, enabling early detection and the development of nursing intervention strategies. From a comprehensive perspective, nursing care should not only address patients' physical needs but also their psychosocial needs.

• Journal of Korean Biological Nursing Science
• /
• v.16 no.3
• /
• pp.157-163
• /
• 2014

Purpose: This study investigated the microorganisms in the hand before and after hand washing, using plain and antibacterial soap. The purpose of this study was to provide details, for educational purposes, of hand washing methods that should be used by college students for their hand hygiene. Methods: This study was arranged using a randomized control group pretest-posttest design. Data obtained through questionnaires were collected from college students in Gangwon Province. This study involved three groups under different conditions. The first and the second group washed their hands with plain and antibacterial soap, respectively. The third group members were educated about hand washing and they then washed their hands with plain soap. In addition, we collected samples to investigate the removal rate of Escherichia coli and Staphylococcus aureus, which can cause bacterial disease, by using sterile swabs from the hands in group 3. Results: The removal rates of bacteria in the first and the second group after hand washing with plain and antimicrobial soap were 62.7% and 76%, respectively. The third group, who were educated concerning proper hand washing, showed a figure of 72.8%. Conclusion: Repeated and more consistent education of college students concerning proper hand washing would be important in order to improve their knowledge, attitude, and performance with regard to hand washing.

• Journal of Korean Clinical Nursing Research
• /
• v.14 no.3
• /
• pp.99-115
• /
• 2008

Purpose: The purpose for this study was to identify the present state of Clinical Nurses with Expanded Role (CNERs) and provide basic data to refine the roles of CNERs. In this study, CNREs refers to nurses who perform techniques traditionally done by doctors and use titles such as clinical nursing specialist, educator with consultation, research assistant, coordinator, physician assistant and special examiner. Method: This study was conducted from September 1 to November 12, 2007. Data from 684 nurses from 38 hospitals who responded to the questionnaire were analyzed with descriptive statistics using the SPSS 14.0 program. Results: The mean percentage of time spent was, for direct practice, 41.1%, for education and counseling, 22.8%, for consultation and coordination, 10.4%, for research, 6.8%, for administration, 8.9% and for other activities, 10.0%. The most frequently implemented CNERs, activities included consultation and education for patients and their families, counseling by telephone, history taking, physical examination, reading examination results, psychosocial assessment, managing treatment, input of prescriptions, and writing up patient records, Although not frequently performed, nurses in some fields carried out invasive procedures and prescribed medication and laboratory tests. Conclusion: Although the number of hospital CNERs are rapidly increasing, there is still confusion about the title and framework as well as standards. Furthermore, because some nurses are prescribing medication and laboratory tests as well as performing techniques not traditionally done by nurses, there is an absolute need for a legalized system and systematic education system for the safety of patients who are being cared by all CNERs.