• Korean Journal of Head & Neck Oncology
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• v.9 no.1
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• pp.25-32
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• 1993

The nodular hyperplasia of the thyroid is a common thyriod disease. Nodular hyperplasia does rarely progress to thyroid cancer. The differentiation of a nodular hyperplasia from a neoplasm may be simple or difficult, both clinically and anatomically. The papillary carcinoma of the thyroid is the most common type of thyroid malignancies. There were few studies about cytogenetic observation in thyroid cancer. But only one case of banding observation in nodular hyperplasia have been reported. In order to compare the chromosomal changes in the thyroid cancer and the noncancerous thyroid disease, we performed cytogenetic analysis in two papillary carcinoma and two nodular hyperplasia after cell culture. The chromosomal pattern of the nodular hyperplasia found was very heterogenous but no clonal abnormaly in both cases was observed. Case I : A modal chromosomal number was in 42-46 range. Chromosome 8, 19, 21. 22 were commonly lost. 9 structural anomalities among 51 analysed cells were observed but they were not clonal. Case II: A modal chromosomal number was 43. Chromosome 17 and 19 were commonly lossed. Common cytogenetic characters of this two nodular hyperplasia are hypodiploidity and very heterogenous chromosomal pattern. The result about the papillary carcinoma are as follow. In one case some numerical and structural chromosomal changes were observed. But they were not clonal abnormality. In another case the chromosomal pattern found was very heterogenous with a clonal abnormality of del(11)(q23). The modal number was 46. The del(11)(q23) a chromosomal change in papillary carcinoma of the thyroid have previously been reported(Eva Olah et al. 1989). We suggest that 11q deletion may be important role to pathogenesis of papillary carcinoma of the thyroid. According to this results, we could not find out specific differences about chromosomal changes and any relationship between the papillary carcinoma and the nodular hyperplasia.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.22 no.1
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• pp.117-124
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• 2009

The p-convergent boundary element method has been proposed to analyze two-dimensional potential problem on the basis of high order Legendre shape functions that have different property comparing with the shape functions in conventional boundary element method. The location of nodes corresponding to high order shape function are not defined along the boundary, called by nodeless node, similar to the p-convergent finite element method. As the order of shape function increases, the collocation point method is used to solve linear simultaneous equations. The collocation patterns of p-convergent boundary element method consist of non-symmetric hierarchial or symmetric non-hierarchical. As the order of shape function increases, the number of collocation point increases. The singular integral that appears in p-convergent boundary element has been calculated by special numeric quadrature technique and semi-analytical integration technique. The L-shape domain problem including singularity in the vicinity of reentrant comer is analyzed and the numerical results show that the relative error is smaller than $10^{-2}%$ range as compared with other results in literatures. In case of same condition, the symmetric p-collocation point pattern shows high accuracy of solution.

• Journal of the Earthquake Engineering Society of Korea
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• v.10 no.6 s.52
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• pp.79-91
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• 2006

A new methodology of guided wave based nondestructive testing (NDT) is developed to detect crack damage in civil infrastructures such as steel bridges without using prior baseline data. In conventional guided wave based techniques, damage is often identified by comparing the "current" data obtained from a potentially damaged condition of a structure with the "past" baseline data collected at the pristine condition of the structure. However, it has been reported that this type of pattern comparison with the baseline data can lead to increased false alarms due to its susceptibility to varying operational and environmental conditions of the structure. To develop a more robust damage diagnosis technique, a new concept of NDT is conceived so that cracks can be detected without direct comparison with previously obtained baseline data. The proposed NDT technique utilizes the polarization characteristics of the piezoelectric wafers attached on the both sides of the thin metal structure. Crack formation creates Lamb wave mode conversion due to a sudden change in the thickness of the structure. Then, the proposed technique instantly detects the appearance of the crack by extracting this mode conversion from the measured Lamb waves even at the presence of changing operational and environmental conditions. Numerical and experimental results are presented to demonstrate the applicability of the proposed technique to crack detection.

• Korean Journal of Veterinary Research
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• v.38 no.4
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• pp.918-928
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• 1998

The present study was done with two aims. First, to evaluate the radiographic measurements of liver volumes in normal and hepatomegaly dogs induced by carbon tetrachloride. Second, to investigate quantitative tissue echo pattern by ultrasonography. Gray level histogram of the normal liver and the kidney were estimated with carbon tetra-chloride intoxication. In normal, r-square for liver volume to body weight was 0.93372, and this showed direct linear regression. Gray level histograms of the normal liver and the kidney were $19.150{\pm}2.490$(mean${\pm}$SD) and $13.175{\pm}2.686$(mean${\pm}$SD) respectively(p < 0.01). Liver parenchymal echogenicity was more hyperechogenic than kidney cortex echogenicity. Liver/Kidney ratio was $1.504{\pm}0.313$ and it can be used relative comparison of liver and kidney parenchymal echogenicity. In carbon-tetrachloride($CCl_4$) intoxication, changes of liver volume appeared to increase up to 24 hours after administration (p < 0.05), and decreased gradually to normal level after 2~5 days. Gray level histogram of liver parenchyma decreased up to 24hours (p < 0.01) after intoxication and then gradually increased to normal level. But that of kidney cortex had no significant change. Liver/Kidney ratio also decreased by 2 days(p < 0.01) and then gradually increased to normal level. On histopathologic features of hepatic tissues in carbon tetrachloride intoxication, both coagulative necrosis of hepatic cell and hemorrhage of centrilobular & midzonal area were identified. Conclusively, plain radiography is a useful diagnostic method for evaluating liver volume in mild hepatomegaly. Especially, it is considered that an adequate numerical processing of the liver length, depth and thoracic width and depth measurement would be helpful. Using gray level histogram, ultrasonographic evaluation was useful objective methods in early diagnosis of diffuse hepatic disease.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.9
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• pp.1364-1373
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• 2015

The purpose of this study was to determine the optimum sodium concentration (0~8%), soaking time (4~20 min) and storage time (0~60 day) for preparation of persimmon jangachi with kochujang sauce using response surface methodology. Physicochemical properties (salinity, pH, Hunter's color value, cutting force, and sensory evaluation) of persimmon kochujang jangachi were analyzed during storage at $20^{\circ}C$ for 60 days. When the proximate composition of persimmon was analyzed, moisture content, crude protein content, crude lipid content, and crude ash content were 85.41%, 0.51%, 0.22%, and 0.20%, respectively. For persimmon kochujang jangachi manufactured with different sodium concentrations, soaking times, and storage times, salinity, pH, Hunter's color value of L, a, and b, color, flavor, taste, texture, and overall preference were represented by a quadratic model. Cutting force was represented by a linear model pattern. In conclusion, the optimal formulation for persimmon kochujang jangachi, as assessed by numerical and graphical optimization methods, was a sodium concentration of 6.91%, soaking time of 11.36 minutes, and storage time of 25.18 days.

• Journal of Dental Rehabilitation and Applied Science
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• v.21 no.2
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• pp.153-167
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• 2005

The purpose of this study was to compare the v-shape thread with the square shape thread of fixture in the view of stress distribution pattern using finite element stress analysis. The finite element model was designed with the parallel placement of two standard fixtures(4.0 mm diameter ${\times}$ 11.5 mm length) on the region of mandibular 1st and 2nd molars. Three dimensional finite element model was created with the components of the implant and surrounding bone. This study simulated loads of 200 N at the central fossa in a axial direction (load A), 200 N at the buccal offset load that is 2 mm apart from central fossa in a axial direction (load B), 200 N at the buccal offset load that was 4 mm apart from central fossa in a axial direction (load C). These forces of load A',B',C' were applied to a $15^{\circ}$ inward oblique direction at that same site with 200 N. Von Mises stress values were recorded and compared in the supporting bone, fixture, and abutment screw. The following results have been made based on this study : 1. The highest stress concentration occurred at the cervical region of the implant fixture. 2. Von Mises stress value of off-site region was higher than that of central fossa region. 3. Square shape thread type showed more even stress distribution in the vertical and oblique force than V-shape thread type. 4. Stress distribution was the most effective in the case of buccal offset load (2, 4 mm distance from central fossa) in the square shape thread type. 5. V-shape thread type revealed higher von Mises stress value than square shape thread type in all environmental condition. The results from numerical analyses concluded that square shape thread type had the lower destructive stress and more stress distribution between the fixture and bone interface than V-shape thread type. Therefore, square shape thread type was regarded as optimal thread configuration in biomechanical concepts.

• Korean Journal of Remote Sensing
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• v.30 no.6
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• pp.731-742
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• 2014

In this study, we developed a new algorithm which can construct model buildings used as a surface boundary in numerical models using GIS with latitudinal and longitudinal information of building vertices. The algorithm established the outer boundary of a building first, by finding segments passing neighboring two vertices of the building and connecting the segments. Then, the algorithm determined the region inside the outer boundary as the building. The new algorithm overcame the limit that the algorithm developed in the previous study had in constructing concave buildings. In addition, the new algorithm successfully constructed a building with complicated shape. To investigate effects of the modification in building shape caused by the building-construction algorithm on flows and pollutant dispersion around buildings, a computational fluid dynamics model was used and three kinds of building type were considered. In the downwind region, patterns in flow and pollutant dispersion were little affected by the modification in building shape caused. However, because of reduction in air space resulted from the building-shape modification, vortex structure was not resolved or smaller vortex was resolved near the buildings. The changes in flow pattern affected dispersion patterns of scalar pollutants emitted around the buildings.

• Korean Journal of Remote Sensing
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• v.34 no.5
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• pp.763-775
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• 2018

In this study, the effects of wind fences on the dispersion of the particles emitted from a constructing site located in the building-congested area in Busan, Korea, using geographic information system (GIS) and a computational fluid dynamics (CFD) model. We averaged the wind speeds observed for 10 years at the Busan automated synoptic observing system (ASOS) and we used the averaged wind speed as the wind speed at the reference height (10 m above the ground level). The numerical simulations were performed for 16 inflow directions, before and after the construction of wind fences with the heights of 5 m and 10 m (total 48 simulations). The detailed flows were analyzed for the northeasterly and south-southwesterly cases which predominantly observed at the Busan ASOS. In the northeasterly case, high concentration appeared at the elementary school next to the construction site due to transport by the airflow coming from the northeast. In the 5-m wind fence case, the wind speeds were slightly weaker and the spread of the fugitive dust was slightly less than those in the no wind fence case. In the 10-m wind fence case, the dust concentration at the elementary school has the maximum reduction of 37%. In the south-southwesterly case, the flow pattern became complicated in the construction site due to the terrain and buildings. Fugitive dust was stagnant at the south side of the construction site but rather spread to the north, increasing the concentration at the elementary school. After the wind fence was built, the concentrations inside the construction site became high as the wind speeds decreased inside, but, the concentrations in the elementary school rather decreased.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.5 no.3
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• pp.186-194
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• 2000

In this study, the oceanic responses to given atmospheric boundary conditions are investigated using a mesoscale ocean circulation model. The numerical experiments are divided into two parts: One is, so called, spin-up experiment and the other is reproduction experiment. The spin-up experiment simulates climatic state of ocean by integrating the ocean model with upper boundary conditions of the monthly mean atmospheric climate data. In the reproduction experiment, for the reproduction of major oceanic changes around Korean Peninsula during the period of 1980-1998 (19 years), the model has been integrated under the boundary condition of the 19year monthly mean atmosphere data. The spined-up state of ocean generated from the spin-up experiment is assigned to the initial boundary condition of the reproduction experiment. In the spin-up experiment, the model properly simulates the major features of circulation structure around Korean Peninsula; such as separation of East Korean Warm Current (EKWC), formation of the polar front, cold water band associated with the small scale eddies in the East Sea, the formation of front along west coast, and the seasonal variation of circulation pattern caused by changing upwind current in the West Sea. In the reproduction experiment, the model has shown the interannual sea surface temperature variations and a warming trend of about 0.5$^{\circ}$C during the period around Korean Peninsula, as in the case of the observation. Therefore, it is concluded that the model is capable of simulating not only the mean states but also the variabilities of ocean under the given atmosphere boundary conditions.

• Journal of the Korean Society for Marine Environment & Energy
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• v.11 no.3
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• pp.160-163
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• 2008

$CO_2$ ocean sequestration is being considered as a way to earn a frame of time to change other industrial life pattern to overcome the global warming crisis. The method is to dilute the captured $CO_2$ into ocean by ejecting the liquefied $CO_2$ through nozzles. The main issue of such method is the effectiveness and safety, and in both problems the rising speed of those LCO2 droplet is the key parameter. In this paper, the rising speed of LCO2 droplets is numerically studied including the effect of the surfactant which can be residing along the density interface of the droplets. A front tracking method with a simple surface tension model is developed and the rising speed of the droplets is carefully investigated with varying the various parameters. It is demonstrated that the variable surface tension can change the deformation of the droplet, the flow near the interface, and the rising speed.