• Title/Summary/Keyword: Nuclear factors

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CORRELATION OF METASTASIS AND PROGNOSTIC FACTORS IN SQUAMOUS CELL CARCINOMA OF HEAD AND NECK (두경부 편평세포암종에서 전이와 예후 인자에 대한 연구)

  • Seo, Gu-Jong;Ryu, Sun-Youl;Kim, Ok-Joon;Choi, Hong-Ran
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.28 no.1
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    • pp.7-15
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    • 2002
  • The present study was carried out to evaluate the correlation of metastasis and prognostic factors in squamous cell carcinoma of head and neck. Examination was performed on a series of thirty-seven patients who were confirmed to squamous cell carcinoma and its lymphatic metastasis by pathologist. Correlations of metastasis and other factors such as angiogenesis, histologic grading, and p53 expression and ras oncogene were studied. The depth of tumors was around 1 to 27mm. Twenty cases were more than 10mm deep, of which seventeen cases were shown lymphatic metastasis. Total score of histologic grading including keratinization, nuclear atypia, growth pattern and intensity of inflammation was ranged from 5 to 10 points. Of these factors, nuclear atypia with intensity of inflammation, and nuclear atypia with growth pattern was correlated with nuclear atypia each. For angiogenesis, number of new-formed vessels were counted 13 to 58 each. Twenty-eight cases were shown to lymphatic metastasis. No correlation with histologic grading and lymphatic metastasis was found. The results of immunohistochemical staining for p53 and ras oncogene revealed that positive cases were 16 and 22, negative for 21 and 15 each. However, both were not correlated with histologic grading and lymphatic metastasis. These results were revealed that angiogenesis was not correlated with lymphatic metastasis of squamous cell carcinoma arising in head and neck. Nuclear atypia with intensity of inflammation and dysplasia with growth pattern were correlated with histologic grading, which suggested that more careful and adequate advice is needed for effective treatment.

Parts Stresss Analysis for Reliability Prediction of Control Module in Plant (부품부하분석을 이용한 발전소 제어모듈의 신뢰도 예측)

  • 김대웅;강희정
    • Journal of Energy Engineering
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    • v.4 no.3
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    • pp.338-343
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    • 1995
  • The objective of this study is to predict the reliability of the electronic control module at ROD control system in nuclear power plant. Maintaining of the reliability is important issue in the complext system like nuclear plower plant, military equipment, satelite system, etc., because the failure of reliability brings etravagant economic loss and deteriorates public acceptance. In addition to the prediction of reliability, the fators affect the reliability including operating condition, environment, temperature and quality factors were analyzed and simulated. The result shows that the quality factors are more critical for the higher reliability than other two factors.

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A Study on the selection of technology alternatives using AHP (AHP를 이용한 기술개발 대안평가에 관한 연구)

  • 이병욱;정수일
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.18 no.36
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    • pp.341-348
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    • 1995
  • The AHP is a good methodology for the multicriterion decision-making process such as nuclear fuel cycle technology selection, which requires consideration of international circumstances, social factors, economic factors as well as technological factors. This paper presents the prioritization of technologies using AHP at back-end fuel cycle development strategy and it would be useful for the national nuclear development planners.

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